{"id":"https://openalex.org/W81118378","doi":null,"title":"Establishing a high risk CKD cohort: cross-sectional analysis and early outcomes","display_name":"Establishing a high risk CKD cohort: cross-sectional analysis and early outcomes","publication_year":2013,"publication_date":"2013-12-01","ids":{"openalex":"https://openalex.org/W81118378","mag":"81118378"},"language":"en","primary_location":{"id":"pmh:oai:etheses.bham.ac.uk:4732","doi":null,"is_oa":true,"landing_page_url":"http://etheses.bham.ac.uk/4732/1/Stringer13PhD.pdf","pdf_url":"http://etheses.bham.ac.uk/4732/1/Stringer13PhD.pdf","source":{"id":"https://openalex.org/S4306402357","display_name":"University of Birmingham Institutional Research Archive (University of Birmingham)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79619799","host_organization_name":"University of Birmingham","host_organization_lineage":["https://openalex.org/I79619799"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://etheses.bham.ac.uk/4732/1/Stringer13PhD.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069881619","display_name":"Stephanie J. Stringer","orcid":"https://orcid.org/0009-0005-3894-8539","observed_orcids":["https://orcid.org/0009-0005-3894-8539"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Stephanie Stringer","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0005-3894-8539","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5069881619"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-kidney-disease","display_name":"chronic kidney disease","score":0.9940000176429749},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.5490000247955322},{"id":"https://openalex.org/keywords/end-stage-kidney-disease-progression","display_name":"end-stage kidney disease progression","score":0.8799999952316284},{"id":"https://openalex.org/keywords/proteinuria","display_name":"proteinuria","score":0.7950000166893005},{"id":"https://openalex.org/keywords/arterial-stiffness","display_name":"arterial stiffness","score":0.8899999856948853},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.8809999823570251},{"id":"https://openalex.org/keywords/periodontitis","display_name":"periodontitis","score":0.9150000214576721},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.8619999885559082},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.9660000205039978},{"id":"https://openalex.org/keywords/unemployment","display_name":"unemployment","score":0.6909999847412109},{"id":"https://openalex.org/keywords/socioeconomic-deprivation","display_name":"socioeconomic deprivation","score":0.9110000133514404},{"id":"https://openalex.org/keywords/comorbidity","display_name":"comorbidities","score":0.8289999961853027},{"id":"https://openalex.org/keywords/estimated-glomerular-filtration-rate","display_name":"estimated glomerular filtration rate","score":0.7020000219345093},{"id":"https://openalex.org/keywords/urinary-albumin-creatinine-ratio","display_name":"urinary albumin-creatinine ratio","score":0.859000027179718}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8684283494949341},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.6704413890838623},{"id":"https://openalex.org/C2775850156","wikidata":"https://www.wikidata.org/wiki/Q4797538","display_name":"Arterial stiffness","level":3,"score":0.607551097869873},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.5645135045051575},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.563393235206604},{"id":"https://openalex.org/C159641895","wikidata":"https://www.wikidata.org/wiki/Q108377937","display_name":"Renal function","level":2,"score":0.5507300496101379},{"id":"https://openalex.org/C2779561371","wikidata":"https://www.wikidata.org/wiki/Q570197","display_name":"Proteinuria","level":3,"score":0.4696734845638275},{"id":"https://openalex.org/C142052008","wikidata":"https://www.wikidata.org/wiki/Q954027","display_name":"Cross-sectional study","level":2,"score":0.4472106099128723},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.4420930743217468},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.4199942946434021},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.2628442645072937},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.2310386598110199},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.14465561509132385}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:etheses.bham.ac.uk:4732","doi":null,"is_oa":true,"landing_page_url":"http://etheses.bham.ac.uk/4732/1/Stringer13PhD.pdf","pdf_url":"http://etheses.bham.ac.uk/4732/1/Stringer13PhD.pdf","source":{"id":"https://openalex.org/S4306402357","display_name":"University of Birmingham Institutional Research Archive (University of Birmingham)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79619799","host_organization_name":"University of Birmingham","host_organization_lineage":["https://openalex.org/I79619799"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"mag:81118378","doi":null,"is_oa":false,"landing_page_url":"https://etheses.bham.ac.uk/id/eprint/4732/","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:etheses.bham.ac.uk:4732","doi":null,"is_oa":true,"landing_page_url":"http://etheses.bham.ac.uk/4732/1/Stringer13PhD.pdf","pdf_url":"http://etheses.bham.ac.uk/4732/1/Stringer13PhD.pdf","source":{"id":"https://openalex.org/S4306402357","display_name":"University of Birmingham Institutional Research Archive (University of Birmingham)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79619799","host_organization_name":"University of Birmingham","host_organization_lineage":["https://openalex.org/I79619799"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W81118378.pdf","grobid_xml":"https://content.openalex.org/works/W81118378.grobid-xml"},"referenced_works_count":203,"referenced_works":["https://openalex.org/W57409683","https://openalex.org/W94211350","https://openalex.org/W122349615","https://openalex.org/W123652815","https://openalex.org/W142014581","https://openalex.org/W175056851","https://openalex.org/W180946569","https://openalex.org/W204815202","https://openalex.org/W1537598136","https://openalex.org/W1550111394","https://openalex.org/W1551495402","https://openalex.org/W1569158144","https://openalex.org/W1570583414","https://openalex.org/W1603091860","https://openalex.org/W1871270394","https://openalex.org/W1892459592","https://openalex.org/W1947857303","https://openalex.org/W1966766282","https://openalex.org/W1966807518","https://openalex.org/W1967345257","https://openalex.org/W1968794790","https://openalex.org/W1969735455","https://openalex.org/W1969791968","https://openalex.org/W1972034726","https://openalex.org/W1975125777","https://openalex.org/W1976102373","https://openalex.org/W1980498033","https://openalex.org/W1982296989","https://openalex.org/W1982966161","https://openalex.org/W1985290917","https://openalex.org/W1985749449","https://openalex.org/W1986272174","https://openalex.org/W1986278462","https://openalex.org/W1986443331","https://openalex.org/W1986911412","https://openalex.org/W1988123101","https://openalex.org/W1989435598","https://openalex.org/W1989445021","https://openalex.org/W1993336979","https://openalex.org/W1994985038","https://openalex.org/W1997907679","https://openalex.org/W2000445173","https://openalex.org/W2004693666","https://openalex.org/W2005064880","https://openalex.org/W2007789292","https://openalex.org/W2009746707","https://openalex.org/W2011627164","https://openalex.org/W2013180282","https://openalex.org/W2016973128","https://openalex.org/W2018074094","https://openalex.org/W2020088825","https://openalex.org/W2021181500","https://openalex.org/W2023141934","https://openalex.org/W2025246651","https://openalex.org/W2029615800","https://openalex.org/W2030239128","https://openalex.org/W2031065729","https://openalex.org/W2031941775","https://openalex.org/W2033128019","https://openalex.org/W2035431836","https://openalex.org/W2036452124","https://openalex.org/W2036644365","https://openalex.org/W2036702893","https://openalex.org/W2038393248","https://openalex.org/W2039499065","https://openalex.org/W2043299715","https://openalex.org/W2043325685","https://openalex.org/W2043575472","https://openalex.org/W2045516356","https://openalex.org/W2046233471","https://openalex.org/W2046809996","https://openalex.org/W2047597909","https://openalex.org/W2048196288","https://openalex.org/W2051236746","https://openalex.org/W2052948254","https://openalex.org/W2053091007","https://openalex.org/W2053959062","https://openalex.org/W2055623658","https://openalex.org/W2055864845","https://openalex.org/W2056196448","https://openalex.org/W2058028170","https://openalex.org/W2061564255","https://openalex.org/W2063868657","https://openalex.org/W2063967797","https://openalex.org/W2066846767","https://openalex.org/W2069882560","https://openalex.org/W2070031467","https://openalex.org/W2071658406","https://openalex.org/W2071823802","https://openalex.org/W2072075701","https://openalex.org/W2074794423","https://openalex.org/W2076692936","https://openalex.org/W2078586154","https://openalex.org/W2084101371","https://openalex.org/W2084692594","https://openalex.org/W2085634927","https://openalex.org/W2086978939","https://openalex.org/W2089082626","https://openalex.org/W2089480273","https://openalex.org/W2091786740","https://openalex.org/W2092276602","https://openalex.org/W2093707453","https://openalex.org/W2095766668","https://openalex.org/W2095948376","https://openalex.org/W2096169471","https://openalex.org/W2096875294","https://openalex.org/W2097501487","https://openalex.org/W2097859955","https://openalex.org/W2099628040","https://openalex.org/W2099843007","https://openalex.org/W2100230373","https://openalex.org/W2100779316","https://openalex.org/W2100860750","https://openalex.org/W2101364180","https://openalex.org/W2102026592","https://openalex.org/W2103015566","https://openalex.org/W2103632941","https://openalex.org/W2103868761","https://openalex.org/W2104613999","https://openalex.org/W2104620275","https://openalex.org/W2104920355","https://openalex.org/W2105493454","https://openalex.org/W2106212115","https://openalex.org/W2106403351","https://openalex.org/W2107031719","https://openalex.org/W2108629029","https://openalex.org/W2109232495","https://openalex.org/W2111346120","https://openalex.org/W2114720788","https://openalex.org/W2115102916","https://openalex.org/W2115421882","https://openalex.org/W2115931410","https://openalex.org/W2117362890","https://openalex.org/W2118286022","https://openalex.org/W2118561903","https://openalex.org/W2120235169","https://openalex.org/W2121637153","https://openalex.org/W2122983268","https://openalex.org/W2123699204","https://openalex.org/W2124174184","https://openalex.org/W2126505950","https://openalex.org/W2127355999","https://openalex.org/W2127906346","https://openalex.org/W2127958770","https://openalex.org/W2130343300","https://openalex.org/W2131684681","https://openalex.org/W2132190388","https://openalex.org/W2132991599","https://openalex.org/W2133872737","https://openalex.org/W2134132325","https://openalex.org/W2134310604","https://openalex.org/W2135326848","https://openalex.org/W2135655969","https://openalex.org/W2136066105","https://openalex.org/W2138225782","https://openalex.org/W2138670606","https://openalex.org/W2138689448","https://openalex.org/W2138785517","https://openalex.org/W2139012057","https://openalex.org/W2140052337","https://openalex.org/W2141348928","https://openalex.org/W2142794866","https://openalex.org/W2146454460","https://openalex.org/W2146901169","https://openalex.org/W2148026472","https://openalex.org/W2148593775","https://openalex.org/W2148983669","https://openalex.org/W2149460835","https://openalex.org/W2149968632","https://openalex.org/W2151287731","https://openalex.org/W2151638673","https://openalex.org/W2152182062","https://openalex.org/W2152281954","https://openalex.org/W2153132322","https://openalex.org/W2154153544","https://openalex.org/W2155965977","https://openalex.org/W2157053766","https://openalex.org/W2158520275","https://openalex.org/W2158978306","https://openalex.org/W2160134719","https://openalex.org/W2160691052","https://openalex.org/W2161985073","https://openalex.org/W2163425767","https://openalex.org/W2165112616","https://openalex.org/W2165817472","https://openalex.org/W2166004824","https://openalex.org/W2166090859","https://openalex.org/W2166543040","https://openalex.org/W2167914628","https://openalex.org/W2168202940","https://openalex.org/W2168536185","https://openalex.org/W2168556156","https://openalex.org/W2170831516","https://openalex.org/W2323905806","https://openalex.org/W2338143469","https://openalex.org/W2375194089","https://openalex.org/W2400183095","https://openalex.org/W2410085699","https://openalex.org/W2416918281","https://openalex.org/W2487377689","https://openalex.org/W2615684303","https://openalex.org/W3010153256","https://openalex.org/W4248649471"],"related_works":["https://openalex.org/W4318672291","https://openalex.org/W3101197606","https://openalex.org/W7220858121","https://openalex.org/W4378347867","https://openalex.org/W4410415444","https://openalex.org/W4205372858","https://openalex.org/W4404469551","https://openalex.org/W1988276235","https://openalex.org/W4316091377","https://openalex.org/W2762496777"],"abstract_inverted_index":{"Introduction":[0],"\\nPatients":[1],"with":[2,59,110,199],"Chronic":[3],"Kidney":[4],"Disease":[5],"(CKD)":[6],"are":[7,96,104],"at":[8],"increased":[9],"risk":[10,61],"of":[11,23,45,57,92,159],"both":[12],"cardiovascular":[13,176],"disease":[14],"and":[15,78,95,136,144,161,167,173,175,180,186,201],"progression":[16],"to":[17,42,213],"end-stage":[18],"kidney":[19,68],"disease;":[20],"our":[21],"understanding":[22],"the":[24,114,124],"factors":[25],"that":[26,205,210],"determine":[27],"these":[28,46],"poor":[29],"outcomes":[30,177],"is":[31,130],"incomplete.":[32],"The":[33,101],"study":[34,56],"reported":[35],"in":[36,106],"this":[37,107],"thesis":[38,108,192],"has":[39],"been":[40],"designed":[41],"address":[43],"some":[44,111],"shortfalls.":[47],"\\n":[48,117,189],"\\nMethods":[49],"\\nI":[50,119],"established":[51],"a":[52,88,203],"prospective,":[53],"observational":[54],"cohort":[55],"patients":[58,198],"high":[60],"CKD":[62,200],"as":[63],"defined":[64],"by":[65],"i)":[66,157],"declining":[67],"function":[69],"and/or":[70,73],"ii)":[71,169],"proteinuria":[72],"iii)":[74,178],"advanced":[75],"(stage":[76],"4":[77],"5)":[79],"CKD.":[80],"Participants":[81],"undergo":[82],"repeated":[83],"detailed":[84],"bio-clinical":[85],"assessment":[86],"over":[87],"follow":[89],"up":[90],"period":[91],"ten":[93],"years":[94],"tracked":[97],"for":[98],"clinical":[99,215],"outcomes.":[100,216],"baseline":[102],"data":[103,112,122],"presented":[105],"along":[109],"form":[113],"six-month":[115],"visit.":[116],"\\nResults":[118],"report":[120],"cross-sectional":[121],"from":[123,197],"first":[125],"500":[126],"participants;":[127],"mean":[128],"age":[129],"65":[131],"years,":[132],"60%":[133],"were":[134],"male":[135,163],"72%":[137],"white":[138],"ethnicity.":[139],"Mean":[140],"eGFR":[141],"was":[142,148],"27mL/min/1.73m2":[143],"median":[145],"urine":[146],"ACR":[147],"26.9":[149],"mg/mmol.":[150],"Detailed":[151],"analyses":[152],"demonstrated":[153],"important":[154,194],"associations":[155],"between":[156],"quality":[158],"life":[160],"unemployment,":[162],"gender,":[164],"deprivation,":[165],"co-morbidity":[166],"inflammation":[168,172,185],"arterial":[170,181,187],"stiffness,":[171],"renal":[174],"periodontitis":[179],"stiffness":[182],"iv)":[183],"mortality,":[184],"stiffness.":[188],"\\nConclusions":[190],"\\nThis":[191],"reports":[193],"new":[195],"findings":[196],"establishes":[202],"resource":[204],"will":[206],"provide":[207],"future":[208],"insights":[209],"should":[211],"contribute":[212],"improving":[214]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}