{"id":"https://openalex.org/W807547958","doi":null,"title":"Funktionelle und morphologische Ver\u00e4nderungen der Gef\u00e4\u00dfwand bei Patienten mit kardiovaskul\u00e4ren Risikofaktoren","display_name":"Funktionelle und morphologische Ver\u00e4nderungen der Gef\u00e4\u00dfwand bei Patienten mit kardiovaskul\u00e4ren Risikofaktoren","publication_year":2006,"publication_date":"2006-01-01","ids":{"openalex":"https://openalex.org/W807547958","mag":"807547958"},"language":"de","primary_location":{"id":"pmh:oai:docserv.uni-duesseldorf.de:3342","doi":null,"is_oa":false,"landing_page_url":"https://docserv.uni-duesseldorf.de/servlets/DocumentServlet?id=3342","pdf_url":null,"source":{"id":"https://openalex.org/S4406922359","display_name":"Univ. Duesseldorf: Duesseldorfer Dokumenten- und Publikationsserver","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dissertation"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082464821","display_name":"Michael Boos","orcid":"https://orcid.org/0000-0002-6138-6248","observed_orcids":["https://orcid.org/0000-0002-6138-6248","https://orcid.org/0000-0001-6414-2452"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Michael Boos","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5082464821"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/arterial-sclerosis","display_name":"arterial sclerosis","score":0.5709999799728394},{"id":"https://openalex.org/keywords/endothelial-dysfunction","display_name":"endothelial dysfunction","score":0.9700000286102295},{"id":"https://openalex.org/keywords/vascular-compliance","display_name":"vascular compliance","score":0.9200000166893005},{"id":"https://openalex.org/keywords/intima-media-thickness","display_name":"intima-media thickness","score":0.7509999871253967},{"id":"https://openalex.org/keywords/vessel-wall-thickening","display_name":"vascular wall thickening","score":0.6159999966621399},{"id":"https://openalex.org/keywords/cardiovascular-risk-factors","display_name":"cardiovascular risk factors","score":0.8610000014305115},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.7129999995231628},{"id":"https://openalex.org/keywords/hypercholesterolemia","display_name":"hypercholesterolemia","score":0.9829999804496765},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.9990000128746033},{"id":"https://openalex.org/keywords/nicotine-abuse","display_name":"nicotine abuse","score":0.7009999752044678},{"id":"https://openalex.org/keywords/early-detection-of-atherosclerosis","display_name":"early detection of atherosclerosis","score":0.6940000057220459},{"id":"https://openalex.org/keywords/duplex-ultrasound","display_name":"duplex ultrasound","score":0.503000020980835},{"id":"https://openalex.org/keywords/elastic-arteries","display_name":"elastic arteries","score":0.46399998664855957},{"id":"https://openalex.org/keywords/muscular-arteries","display_name":"muscular arteries","score":0.9660000205039978},{"id":"https://openalex.org/keywords/carotid-artery","display_name":"carotid artery","score":0.593999981880188},{"id":"https://openalex.org/keywords/noninvasive-vascular-imaging","display_name":"noninvasive vascular imaging","score":0.5609999895095825},{"id":"https://openalex.org/keywords/atherogenesis","display_name":"atherogenesis","score":0.3540000021457672},{"id":"https://openalex.org/keywords/endothelium-dependent-vasodilation","display_name":"endothelium-dependent vasodilation","score":0.4359999895095825}],"concepts":[{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.7931290864944458},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6610637903213501}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:docserv.uni-duesseldorf.de:3342","doi":null,"is_oa":false,"landing_page_url":"https://docserv.uni-duesseldorf.de/servlets/DocumentServlet?id=3342","pdf_url":null,"source":{"id":"https://openalex.org/S4406922359","display_name":"Univ. Duesseldorf: Duesseldorfer Dokumenten- und Publikationsserver","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dissertation"},{"id":"mag:807547958","doi":null,"is_oa":false,"landing_page_url":"https://docserv.uni-duesseldorf.de/servlets/DocumentServlet?id=3342","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":160,"referenced_works":["https://openalex.org/W70198236","https://openalex.org/W77900456","https://openalex.org/W128011898","https://openalex.org/W1512144932","https://openalex.org/W1515618057","https://openalex.org/W1555489744","https://openalex.org/W1607892649","https://openalex.org/W1623505186","https://openalex.org/W1845594264","https://openalex.org/W1854161682","https://openalex.org/W1965116502","https://openalex.org/W1965205653","https://openalex.org/W1972202718","https://openalex.org/W1977181703","https://openalex.org/W1978343052","https://openalex.org/W1979807766","https://openalex.org/W1980097897","https://openalex.org/W1980445357","https://openalex.org/W1982362818","https://openalex.org/W1984187686","https://openalex.org/W1985431943","https://openalex.org/W1985700677","https://openalex.org/W1989760753","https://openalex.org/W1990864597","https://openalex.org/W1992202750","https://openalex.org/W1995800794","https://openalex.org/W1996728375","https://openalex.org/W1997122358","https://openalex.org/W1999502024","https://openalex.org/W2000881220","https://openalex.org/W2001322138","https://openalex.org/W2003667937","https://openalex.org/W2003803897","https://openalex.org/W2006911187","https://openalex.org/W2007141088","https://openalex.org/W2009148489","https://openalex.org/W2009641798","https://openalex.org/W2011841738","https://openalex.org/W2014231512","https://openalex.org/W2014607508","https://openalex.org/W2014914292","https://openalex.org/W2016746678","https://openalex.org/W2016880082","https://openalex.org/W2017499355","https://openalex.org/W2022605831","https://openalex.org/W2024950456","https://openalex.org/W2025130216","https://openalex.org/W2027499184","https://openalex.org/W2028669985","https://openalex.org/W2032071324","https://openalex.org/W2032974881","https://openalex.org/W2034122612","https://openalex.org/W2038273086","https://openalex.org/W2039126062","https://openalex.org/W2042027402","https://openalex.org/W2044290562","https://openalex.org/W2044634951","https://openalex.org/W2049748917","https://openalex.org/W2050304253","https://openalex.org/W2050548878","https://openalex.org/W2055720801","https://openalex.org/W2057116025","https://openalex.org/W2057147472","https://openalex.org/W2058063912","https://openalex.org/W2058331351","https://openalex.org/W2059107906","https://openalex.org/W2059793862","https://openalex.org/W2060003084","https://openalex.org/W2063506869","https://openalex.org/W2064666060","https://openalex.org/W2064809465","https://openalex.org/W2065314431","https://openalex.org/W2071680557","https://openalex.org/W2073274738","https://openalex.org/W2075063725","https://openalex.org/W2077244492","https://openalex.org/W2080943041","https://openalex.org/W2081658317","https://openalex.org/W2082089299","https://openalex.org/W2082162243","https://openalex.org/W2082291507","https://openalex.org/W2083481797","https://openalex.org/W2086045918","https://openalex.org/W2090443364","https://openalex.org/W2091181219","https://openalex.org/W2091983820","https://openalex.org/W2094918238","https://openalex.org/W2096237016","https://openalex.org/W2096656439","https://openalex.org/W2106478344","https://openalex.org/W2108249447","https://openalex.org/W2109667273","https://openalex.org/W2111562769","https://openalex.org/W2112280221","https://openalex.org/W2113446450","https://openalex.org/W2114098249","https://openalex.org/W2115268091","https://openalex.org/W2116693349","https://openalex.org/W2121900849","https://openalex.org/W2122648697","https://openalex.org/W2122758598","https://openalex.org/W2122787929","https://openalex.org/W2123258346","https://openalex.org/W2123403285","https://openalex.org/W2124164874","https://openalex.org/W2126090408","https://openalex.org/W2127523891","https://openalex.org/W2128247746","https://openalex.org/W2128319000","https://openalex.org/W2129300622","https://openalex.org/W2131382850","https://openalex.org/W2132440861","https://openalex.org/W2133496376","https://openalex.org/W2134037613","https://openalex.org/W2134138509","https://openalex.org/W2136503561","https://openalex.org/W2140148701","https://openalex.org/W2141337462","https://openalex.org/W2144127447","https://openalex.org/W2145559517","https://openalex.org/W2145899271","https://openalex.org/W2147275213","https://openalex.org/W2147346175","https://openalex.org/W2148637873","https://openalex.org/W2149042652","https://openalex.org/W2149572242","https://openalex.org/W2150274268","https://openalex.org/W2151241107","https://openalex.org/W2157453590","https://openalex.org/W2157598728","https://openalex.org/W2158424661","https://openalex.org/W2160094856","https://openalex.org/W2162558534","https://openalex.org/W2162759134","https://openalex.org/W2163223476","https://openalex.org/W2168378909","https://openalex.org/W2170541055","https://openalex.org/W2171271146","https://openalex.org/W2171404147","https://openalex.org/W2181682560","https://openalex.org/W2217533211","https://openalex.org/W2229977340","https://openalex.org/W2253649569","https://openalex.org/W2318963073","https://openalex.org/W2324841714","https://openalex.org/W2326823272","https://openalex.org/W2329306090","https://openalex.org/W2329619445","https://openalex.org/W2343351896","https://openalex.org/W2401429484","https://openalex.org/W2405078949","https://openalex.org/W2410578900","https://openalex.org/W2413819262","https://openalex.org/W2417124267","https://openalex.org/W2441831948","https://openalex.org/W2472621252","https://openalex.org/W2617392052","https://openalex.org/W3112270648","https://openalex.org/W4230196112","https://openalex.org/W4317523496"],"related_works":["https://openalex.org/W466884397","https://openalex.org/W2014210519","https://openalex.org/W2398393672","https://openalex.org/W2440148288","https://openalex.org/W1965384828","https://openalex.org/W2416604276","https://openalex.org/W1409609652","https://openalex.org/W2271258082","https://openalex.org/W2516325686","https://openalex.org/W2615263026"],"abstract_inverted_index":{"Veranderungen":[0,116,151,207],"der":[1,9,21,38,42,48,50,81,83,102,133,149,152,166,174,196,208,219,250,266,274],"Gefaswand":[2,209],"in":[3,20,101,223,227,230,260],"Form":[4],"einer":[5,27,46,98,241,246],"endothelialen":[6,242],"Dysfunktion,":[7,203],"Erniedrigung":[8],"vaskularen":[10,51],"Compliance":[11,52],"und":[12,41,53,57,119,143,190,205],"strukturelle":[13],"Wandverdickungen":[14,55],"scheinen":[15,58],"eine":[16,85,139,162,201],"zentrale":[17],"Rolle":[18],"sowohl":[19,181,222,239],"Entstehung,":[22],"als":[23,184,225,244],"auch":[24,110,185,226,245],"dem":[25],"Fortschreiten":[26],"Arteriosklerose":[28,84,153,175,275],"zuzukommen.":[29],"Kardiovaskulare":[30,235],"Risikofaktoren":[31,217,236],"wie":[32],"die":[33,36,259],"arterielle":[34],"Hypertonie,":[35],"Hypercholesterinamie,":[37],"Diabetes":[39],"mellitus":[40],"Nikotinabusus":[43],"sind":[44],"mit":[45,148,165,240],"Storung":[47],"Endothelfunktion,":[49],"struktureller":[54],"assoziiert":[56],"hieruber":[59],"ihre":[60],"proatherogene":[61],"Wirkung":[62],"zu":[63,146,176],"vermitteln.":[64],"Neuere":[65],"klinische":[66],"Ansatze":[67],"deuten":[68],"darauf":[69],"hin,":[70],"dass":[71,258],"alle":[72,171],"diese":[73,113],"drei":[74,114,172],"Marker":[75],"therapeutisch":[76],"ruckfuhrbar":[77],"sein":[78],"konnen.":[79,157],"Obwohl":[80],"Fruherkennung":[82,97],"grose":[86],"soziookonomische":[87],"Bedeutung":[88],"zukommt,":[89],"existiert":[90],"derzeit":[91],"noch":[92],"kein":[93],"einfaches":[94],"Verfahren":[95],"zur":[96,272],"Arteriosklerose,":[99],"welches":[100],"klinischen":[103],"Routine":[104],"eingesetzt":[105],"wird.":[106],"Unklar":[107],"war":[108,136,169],"bisher":[109],"inwiefern":[111],"sich":[112],"unterschiedlichen":[115],"untereinander":[117],"beeinflussen":[118],"ob":[120],"sie":[121],"an":[122,182,186,265],"histologisch":[123],"unterschiedlich":[124],"aufgebauten":[125],"Gefasen":[126],"im":[127],"gleichen":[128],"Ausmas":[129,232],"verandert":[130],"sind.":[131],"Ziel":[132],"vorliegenden":[134],"Arbeit":[135,262],"es":[137,167],"daher":[138],"einfach":[140],"anwendbare":[141],"nicht-invasive":[142],"kostengunstige":[144],"Ultraschalluntersuchung":[145,264],"entwickeln":[147],"fruhe":[150],"hochsensitiv":[154,210],"erfasst":[155,211],"werden":[156],"In":[158,214],"diesem":[159],"Zusammenhang":[160],"wurde":[161,180,256],"Untersuchungsmethode":[163],"entwickelt":[164],"moglich":[168],"simultan":[170,200],"Fruhmarker":[173],"quantifizieren.":[177],"Diese":[178],"Untersuchung":[179],"elastischen":[183,224],"muskularen":[187,228],"Leitungsarterien":[188,229],"angewendet":[189],"verglichen.":[191],"1.":[193],"Mit":[194],"Hilfe":[195],"digitalen":[197],"Duplexsonographie":[198],"konnen":[199],"Endotheliale":[202],"morphologische":[204],"physiko-mechanische":[206],"werden.":[212],"2.":[213],"Anwesenheit":[215],"kardiovaskularer":[216],"ist":[218],"Intima-Media":[220],"Komplex":[221],"gleichem":[231],"verdickt.":[233],"3.":[234],"gehen":[237],"parallel":[238],"Dysfunktion":[243],"Verdickung":[247],"des":[248],"Intima-Media-Komplexes":[249],"A.":[251],"brachialis":[252,268],"einher.":[253],"Daraus":[255],"geschlossen,":[257],"dieser":[261],"vorgestellte":[263],"Arteria":[267],"einen":[269],"Wichtigen":[270],"Beitrag":[271],"Fruhdiagnose":[273],"leisten":[276],"kann.":[277]},"counts_by_year":[],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-06-24T00:00:00"}