{"id":"https://openalex.org/W80532103","doi":"https://doi.org/10.1096/fasebj.21.6.a1085","title":"Effect of a Brown Algae Extract on Postprandial Glucose Control in Neonatal Diabetic and Obese Rats","display_name":"Effect of a Brown Algae Extract on Postprandial Glucose Control in Neonatal Diabetic and Obese Rats","publication_year":2007,"publication_date":"2007-01-01","ids":{"openalex":"https://openalex.org/W80532103","doi":"https://doi.org/10.1096/fasebj.21.6.a1085","mag":"80532103"},"language":"en","primary_location":{"id":"doi:10.1096/fasebj.21.6.a1085","doi":"https://doi.org/10.1096/fasebj.21.6.a1085","is_oa":false,"landing_page_url":"https://doi.org/10.1096/fasebj.21.6.a1085","pdf_url":null,"source":{"id":"https://openalex.org/S25293849","display_name":"The FASEB Journal","issn_l":"0892-6638","issn":["0892-6638","1530-6860"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The FASEB Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091322910","display_name":"Jeongsu Nam","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I104338594","display_name":"Inje University","ror":"https://ror.org/04xqwq985","country_code":"KR","type":"education","lineage":["https://openalex.org/I104338594"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jeongsu Nam","raw_affiliation_strings":["Biomedical Laboratory Science, Inje University, 607 Obang-Dong, Gimhae, Korea, Republic of"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Laboratory Science, Inje University, 607 Obang-Dong, Gimhae, Korea, Republic of","institution_ids":["https://openalex.org/I104338594"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Wonjun Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I104338594","display_name":"Inje University","ror":"https://ror.org/04xqwq985","country_code":"KR","type":"education","lineage":["https://openalex.org/I104338594"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Wonjun Lee","raw_affiliation_strings":["Biomedical Laboratory Science, Inje University, 607 Obang-Dong, Gimhae, Korea, Republic of"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Laboratory Science, Inje University, 607 Obang-Dong, Gimhae, Korea, Republic of","institution_ids":["https://openalex.org/I104338594"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085606375","display_name":"Imsil Yoon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I104338594","display_name":"Inje University","ror":"https://ror.org/04xqwq985","country_code":"KR","type":"education","lineage":["https://openalex.org/I104338594"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Imsil Yoon","raw_affiliation_strings":["Biomedical Laboratory Science, Inje University, 607 Obang-Dong, Gimhae, Korea, Republic of"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Laboratory Science, Inje University, 607 Obang-Dong, Gimhae, Korea, Republic of","institution_ids":["https://openalex.org/I104338594"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103294117","display_name":"Muweon Kang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I104338594","display_name":"Inje University","ror":"https://ror.org/04xqwq985","country_code":"KR","type":"education","lineage":["https://openalex.org/I104338594"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Muweon Kang","raw_affiliation_strings":["Biomedical Laboratory Science, Inje University, 607 Obang-Dong, Gimhae, Korea, Republic of"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Laboratory Science, Inje University, 607 Obang-Dong, Gimhae, Korea, Republic of","institution_ids":["https://openalex.org/I104338594"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101925742","display_name":"Hyunsoo Jang","orcid":"https://orcid.org/0000-0001-9012-2383","observed_orcids":["https://orcid.org/0000-0001-9012-2383"]},"institutions":[{"id":"https://openalex.org/I104338594","display_name":"Inje University","ror":"https://ror.org/04xqwq985","country_code":"KR","type":"education","lineage":["https://openalex.org/I104338594"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Hyunsoo Jang","raw_affiliation_strings":["Biomedical Laboratory Science, Inje University, 607 Obang-Dong, Gimhae, Korea, Republic of"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Laboratory Science, Inje University, 607 Obang-Dong, Gimhae, Korea, Republic of","institution_ids":["https://openalex.org/I104338594"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063798948","display_name":"Jihye Youn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I104338594","display_name":"Inje University","ror":"https://ror.org/04xqwq985","country_code":"KR","type":"education","lineage":["https://openalex.org/I104338594"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jihye Youn","raw_affiliation_strings":["Biomedical Laboratory Science, Inje University, 607 Obang-Dong, Gimhae, Korea, Republic of"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Laboratory Science, Inje University, 607 Obang-Dong, Gimhae, Korea, Republic of","institution_ids":["https://openalex.org/I104338594"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100417338","display_name":"Boram Kim","orcid":"https://orcid.org/0000-0001-5695-8902","observed_orcids":["https://orcid.org/0000-0001-5695-8902"]},"institutions":[{"id":"https://openalex.org/I104338594","display_name":"Inje University","ror":"https://ror.org/04xqwq985","country_code":"KR","type":"education","lineage":["https://openalex.org/I104338594"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Boram Kim","raw_affiliation_strings":["Biomedical Laboratory Science, Inje University, 607 Obang-Dong, Gimhae, Korea, Republic of"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Laboratory Science, Inje University, 607 Obang-Dong, Gimhae, Korea, Republic of","institution_ids":["https://openalex.org/I104338594"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052971913","display_name":"Hyejoo Kong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I104338594","display_name":"Inje University","ror":"https://ror.org/04xqwq985","country_code":"KR","type":"education","lineage":["https://openalex.org/I104338594"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Hyejoo Kong","raw_affiliation_strings":["Biomedical Laboratory Science, Inje University, 607 Obang-Dong, Gimhae, Korea, Republic of"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Laboratory Science, Inje University, 607 Obang-Dong, Gimhae, Korea, Republic of","institution_ids":["https://openalex.org/I104338594"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100657847","display_name":"Ki\u2010Hoon Kim","orcid":"https://orcid.org/0000-0002-8654-4046","observed_orcids":["https://orcid.org/0000-0002-8654-4046"]},"institutions":[{"id":"https://openalex.org/I104338594","display_name":"Inje University","ror":"https://ror.org/04xqwq985","country_code":"KR","type":"education","lineage":["https://openalex.org/I104338594"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Kihoon Kim","raw_affiliation_strings":["Biomedical Laboratory Science, Inje University, 607 Obang-Dong, Gimhae, Korea, Republic of"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Laboratory Science, Inje University, 607 Obang-Dong, Gimhae, Korea, Republic of","institution_ids":["https://openalex.org/I104338594"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100760941","display_name":"Yong Ho Kim","orcid":"https://orcid.org/0000-0001-7527-0134","observed_orcids":["https://orcid.org/0000-0001-7527-0134"]},"institutions":[{"id":"https://openalex.org/I104338594","display_name":"Inje University","ror":"https://ror.org/04xqwq985","country_code":"KR","type":"education","lineage":["https://openalex.org/I104338594"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Yongho Kim","raw_affiliation_strings":["Biomedical Laboratory Science, Inje University, 607 Obang-Dong, Gimhae, Korea, Republic of"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Laboratory Science, Inje University, 607 Obang-Dong, Gimhae, Korea, Republic of","institution_ids":["https://openalex.org/I104338594"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101533075","display_name":"Dongseok Lee","orcid":"https://orcid.org/0000-0002-6960-9127","observed_orcids":["https://orcid.org/0000-0002-6960-9127"]},"institutions":[{"id":"https://openalex.org/I104338594","display_name":"Inje University","ror":"https://ror.org/04xqwq985","country_code":"KR","type":"education","lineage":["https://openalex.org/I104338594"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Dongseok Lee","raw_affiliation_strings":["Biomedical Laboratory Science, Inje University, 607 Obang-Dong, Gimhae, Korea, Republic of"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Laboratory Science, Inje University, 607 Obang-Dong, Gimhae, Korea, Republic of","institution_ids":["https://openalex.org/I104338594"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102422126","display_name":"Hyunju Choi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I104338594","display_name":"Inje University","ror":"https://ror.org/04xqwq985","country_code":"KR","type":"education","lineage":["https://openalex.org/I104338594"]},{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["KR","US"],"is_corresponding":false,"raw_author_name":"Hyunju Choi","raw_affiliation_strings":["Biomedical Laboratory Science, Inje University, 607 Obang-Dong, Gimhae, Korea, Republic of","Nutritional Biology, University of California, Davis, 1 Shields Avenue, Davis, CA, 95616"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Laboratory Science, Inje University, 607 Obang-Dong, Gimhae, Korea, Republic of","institution_ids":["https://openalex.org/I104338594"]},{"raw_affiliation_string":"Nutritional Biology, University of California, Davis, 1 Shields Avenue, Davis, CA, 95616","institution_ids":["https://openalex.org/I84218800"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3740,"currency":"USD","value_usd":3740},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.01107672,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"21","issue":"6","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11390","display_name":"Seaweed-derived Bioactive Compounds","score":0.8672000169754028,"subfield":{"id":"https://openalex.org/subfields/1104","display_name":"Aquatic Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11390","display_name":"Seaweed-derived Bioactive Compounds","score":0.8672000169754028,"subfield":{"id":"https://openalex.org/subfields/1104","display_name":"Aquatic Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.13210000097751617,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12964","display_name":"Diet, Metabolism, and Disease","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/brown-algae-extract","display_name":"brown algae extract","score":0.9990000128746033},{"id":"https://openalex.org/keywords/postprandial-blood-glucose","display_name":"postprandial blood glucose","score":0.8920000195503235},{"id":"https://openalex.org/keywords/neonatal-diabetes-mellitus","display_name":"neonatal diabetes","score":0.7360000014305115},{"id":"https://openalex.org/keywords/streptozotocin-induced-diabetes","display_name":"streptozotocin-induced diabetes","score":0.9900000095367432},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.6779999732971191},{"id":"https://openalex.org/keywords/high-fat-diet","display_name":"high-fat diet","score":0.9340000152587891},{"id":"https://openalex.org/keywords/serum-glucose","display_name":"serum glucose","score":0.7480000257492065},{"id":"https://openalex.org/keywords/antidiabetic-effect","display_name":"antidiabetic effect","score":0.5429999828338623},{"id":"https://openalex.org/keywords/seaweed","display_name":"seaweed","score":0.42899999022483826}],"concepts":[{"id":"https://openalex.org/C2778199505","wikidata":"https://www.wikidata.org/wiki/Q2992990","display_name":"Postprandial","level":3,"score":0.9684326648712158},{"id":"https://openalex.org/C2778197599","wikidata":"https://www.wikidata.org/wiki/Q170002","display_name":"Maltose","level":3,"score":0.7229552268981934},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6452209949493408},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6211881637573242},{"id":"https://openalex.org/C559758991","wikidata":"https://www.wikidata.org/wiki/Q37868","display_name":"Algae","level":2,"score":0.5359405279159546},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.47972267866134644},{"id":"https://openalex.org/C2778977261","wikidata":"https://www.wikidata.org/wiki/Q11358","display_name":"Carbohydrate","level":2,"score":0.468772828578949},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.44625455141067505},{"id":"https://openalex.org/C140793950","wikidata":"https://www.wikidata.org/wiki/Q168091","display_name":"Animal science","level":1,"score":0.36874085664749146},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.35911959409713745},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3294111490249634},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.2191600799560547},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.14959019422531128},{"id":"https://openalex.org/C2778597767","wikidata":"https://www.wikidata.org/wiki/Q4027534","display_name":"Sucrose","level":2,"score":0.08694201707839966}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1096/fasebj.21.6.a1085","doi":"https://doi.org/10.1096/fasebj.21.6.a1085","is_oa":false,"landing_page_url":"https://doi.org/10.1096/fasebj.21.6.a1085","pdf_url":null,"source":{"id":"https://openalex.org/S25293849","display_name":"The FASEB Journal","issn_l":"0892-6638","issn":["0892-6638","1530-6860"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The FASEB Journal","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9789000153541565,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G6627038494","display_name":null,"funder_award_id":"KRF\u2010F00014, BK21","funder_id":"https://openalex.org/F4320307266","funder_display_name":"Foundation for Ichthyosis and Related Skin Types"}],"funders":[{"id":"https://openalex.org/F4320307266","display_name":"Foundation for Ichthyosis and Related Skin Types","ror":"https://ror.org/01fq70c03"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2370097205","https://openalex.org/W4200500980","https://openalex.org/W4389553352","https://openalex.org/W22097439","https://openalex.org/W2613128641","https://openalex.org/W4361009261","https://openalex.org/W4296327522","https://openalex.org/W4256144426","https://openalex.org/W2336484606","https://openalex.org/W6920799142"],"abstract_inverted_index":{"In":[0,132],"this":[1],"study,":[2],"the":[3,29,82,115],"effect":[4,142],"of":[5],"brown":[6,78,86,119,135],"algae":[7,79,87,120,136],"extract":[8,80,88,121,137],"on":[9,143],"postprandial":[10,145],"glucose":[11,92,112,146],"control":[12,129],"was":[13,22,57],"examined":[14],"in":[15,62,110,118,128,148,164],"male":[16],"Sprague-Dawley":[17],"rats.":[18,151],"Neonatal":[19],"diabetes":[20],"mellitus":[21],"induced":[23],"by":[24,96,153],"Stretozotocin":[25],"i.p.":[26],"injection":[27],"to":[28,64],"1":[30],"day":[31],"old":[32],"pups.":[33],"When":[34],"these":[35],"rats":[36],"reached":[37],"approximately":[38],"300g":[39],"body":[40],"weight,":[41],"a":[42,97,134,140],"high":[43],"fat":[44],"diet":[45],"(40%":[46],"energy":[47],"as":[48,51,54,89],"fat,":[49],"40%":[50],"carbohydrate,":[52],"and":[53,81,158,161,166],"20%":[55],"protein)":[56],"fed":[58],"for":[59],"two":[60,72],"weeks":[61],"order":[63],"induce":[65],"obesity.":[66],"Rats":[67],"were":[68,94,123],"then":[69],"divided":[70],"into":[71],"groups:":[73],"one":[74],"group":[75,84,122,130],"with":[76],"5%":[77],"other":[83],"w/o":[85],"control.":[90],"Postprandial":[91],"levels":[93,113,147],"measured":[95],"maltose":[98],"oral":[99],"loading":[100],"test":[101],"(0.2g":[102],"maltose/kg":[103],"Bwt)":[104],"after":[105],"12hr":[106],"overnight":[107],"fasting.":[108],"Increments":[109],"serum":[111],"during":[114],"0~180":[116],"min":[117],"significantly":[124],"lower":[125],"than":[126],"those":[127],"(p<0.05).":[131],"conclusion,":[133],"may":[138],"have":[139],"beneficial":[141],"controlling":[144],"diabetic":[149],"obese":[150],"(Supported":[152],"KRF-F00014,":[154],"BK21,":[155],"NURI,":[156],"FIRST,":[157],"Inje":[159],"Research":[160],"Scholarship":[162],"Foundation":[163],"2005":[165],"2006)":[167]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}