{"id":"https://openalex.org/W79875193","doi":null,"title":"[Iodine and delayed immunity].","display_name":"[Iodine and delayed immunity].","publication_year":1986,"publication_date":"1986-05-07","ids":{"openalex":"https://openalex.org/W79875193","mag":"79875193","pmid":"https://pubmed.ncbi.nlm.nih.gov/3714096"},"language":"it","primary_location":{"id":"pmid:3714096","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3714096","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Minerva medica","raw_type":"Comparative Study"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"L Marani","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L Marani","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5103165034","display_name":"S. Venturi","orcid":"https://orcid.org/0000-0003-1718-7927","observed_orcids":["https://orcid.org/0000-0003-1718-7927"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S Venturi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.00627023,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"77","issue":"19","first_page":"805","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9678000211715698,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9678000211715698,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14072","display_name":"Immunotoxicology and immune responses","score":0.004699999932199717,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10915","display_name":"Trace Elements in Health","score":0.003800000064074993,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/iodine-therapy","display_name":"iodine therapy","score":0.9269999861717224},{"id":"https://openalex.org/keywords/delayed-type-hypersensitivity","display_name":"delayed-type hypersensitivity","score":0.8650000095367432},{"id":"https://openalex.org/keywords/immune-response","display_name":"immune response","score":0.7680000066757202},{"id":"https://openalex.org/keywords/endemic-goiter","display_name":"endemic goiter","score":0.7160000205039978},{"id":"https://openalex.org/keywords/lugol-solution","display_name":"Lugol solution","score":0.8240000009536743},{"id":"https://openalex.org/keywords/lymphocyte-stimulation","display_name":"lymphocyte stimulation","score":0.828000009059906},{"id":"https://openalex.org/keywords/infants","display_name":"infants","score":0.4699999988079071},{"id":"https://openalex.org/keywords/leprosy","display_name":"leprosy","score":0.9139999747276306},{"id":"https://openalex.org/keywords/syphilis","display_name":"syphilis","score":0.7710000276565552},{"id":"https://openalex.org/keywords/sporotrichosis","display_name":"sporotrichosis","score":0.7599999904632568},{"id":"https://openalex.org/keywords/sweet-syndrome","display_name":"Sweet syndrome","score":0.722000002861023},{"id":"https://openalex.org/keywords/erythema-multiforme","display_name":"erythema multiforme","score":0.8479999899864197},{"id":"https://openalex.org/keywords/nodular-vasculitis","display_name":"nodular vasculitis","score":0.8190000057220459},{"id":"https://openalex.org/keywords/erythema-nodosum","display_name":"erythema nodosum","score":0.9169999957084656},{"id":"https://openalex.org/keywords/panniculitis","display_name":"panniculitis","score":0.8149999976158142}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6773154139518738},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6709494590759277},{"id":"https://openalex.org/C2779121184","wikidata":"https://www.wikidata.org/wiki/Q1166142","display_name":"Erythema","level":2,"score":0.5822769403457642},{"id":"https://openalex.org/C2777351567","wikidata":"https://www.wikidata.org/wiki/Q908822","display_name":"Toxoid","level":4,"score":0.578302800655365},{"id":"https://openalex.org/C539932907","wikidata":"https://www.wikidata.org/wiki/Q1103","display_name":"Iodine","level":2,"score":0.5731731057167053},{"id":"https://openalex.org/C2777410594","wikidata":"https://www.wikidata.org/wiki/Q1363738","display_name":"Erythema nodosum","level":3,"score":0.5392770171165466},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3854232430458069},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.35778748989105225},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.34304141998291016},{"id":"https://openalex.org/C2780801004","wikidata":"https://www.wikidata.org/wiki/Q1415366","display_name":"Immunization","level":3,"score":0.14622268080711365},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.098568856716156},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D002634","descriptor_name":"Chemotaxis, Leukocyte","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006043","descriptor_name":"Goiter, Endemic","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006043","descriptor_name":"Goiter, Endemic","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006968","descriptor_name":"Hypersensitivity, Delayed","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D007454","descriptor_name":"Iodides","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D007455","descriptor_name":"Iodine","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":false},{"descriptor_ui":"D007455","descriptor_name":"Iodine","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D007455","descriptor_name":"Iodine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D007558","descriptor_name":"Italy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008213","descriptor_name":"Lymphocyte Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009000","descriptor_name":"Monocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D012882","descriptor_name":"Skin Tests","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D012996","descriptor_name":"Solutions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013745","descriptor_name":"Tetanus Toxoid","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:3714096","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3714096","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Minerva medica","raw_type":"Comparative Study"},{"id":"mag:79875193","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3714096","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W205933644","https://openalex.org/W2376761243","https://openalex.org/W94160132","https://openalex.org/W2392759580","https://openalex.org/W2359993338","https://openalex.org/W2037129253","https://openalex.org/W1441649678","https://openalex.org/W245115962","https://openalex.org/W7023749549","https://openalex.org/W2410558951"],"abstract_inverted_index":{"Iodine":[0,53],"was":[1,126,140,153,166,187],"and":[2,34,69,93,120,136,144,147],"is":[3,14,74,221,237],"sometimes":[4],"used":[5,57],"therapeutically":[6],"in":[7,23,58,61,64,78,99,164,189,202],"various":[8],"pathologies":[9],"where":[10,37],"the":[11,50,79,129,172,190,194,197,203],"immune":[12,94,124,226,235],"mechanism":[13,230],"known":[15],"to":[16,27,86,214,239],"play":[17],"a":[18,88,114,137],"dominant":[19],"role.":[20],"It":[21],"has":[22],"fact":[24],"been":[25],"administered":[26],"patients":[28],"with":[29],"tubercular":[30],"granulomatous,":[31],"lepromatous,":[32],"syphilitic":[33],"mycotic":[35],"lesions":[36],"it":[38],"facilitates":[39],"cure.":[40],"This":[41],"effect":[42],"does":[43],"not":[44],"depend":[45],"on":[46,49],"iodine's":[47],"action":[48],"micro-organism":[51],"responsible.":[52],"may":[54],"also":[55,75],"be":[56,240],"Villanova-Panol":[59],"Panniculitis,":[60],"erythema":[62,67],"nodosum,":[63],"nodular":[65],"vasculitis,":[66],"multiforme":[68],"Sweet's":[70],"syndrome.":[71],"Oral":[72],"iodine":[73,92,219,233],"very":[76],"effective":[77],"lymphatic-cutaneous":[80],"form":[81],"of":[82,102,159,175,193],"sporotrichosis.":[83],"In":[84],"order":[85],"establish":[87],"relationship":[89],"between":[90,142],"dietary":[91],"response,":[95],"607":[96],"infants":[97],"residing":[98],"an":[100,157,217],"area":[101],"endemic":[103],"goitre":[104],"were":[105,108,182],"studied:":[106],"215":[107],"given":[109],"Lugol":[110],"solution":[111],"(2":[112],"drops":[113],"week":[115],"for":[116,223],"about":[117],"8":[118],"months)":[119],"392":[121],"not.":[122],"The":[123,151,211,228],"response":[125,236],"assessed":[127],"by":[128,231],"skin":[130,200],"test":[131,152,201],"method":[132],"using":[133],"tetanic":[134,198],"toxoid":[135,199],"clear":[138],"correlation":[139],"shown":[141,167],"this":[143],"lymphocyte":[145],"stimulation":[146],"monocytic":[148],"chemotaxis":[149],"tests.":[150],"considered":[154,206],"positive":[155],"when":[156],"infiltration":[158],"at":[160],"least":[161],"5":[162],"mm":[163],"diameter":[165,192],"after":[168,196],"48":[169],"hours":[170],"(in":[171],"U.S.":[173],"80%":[174],"paediatric":[176],"cases":[177],"aged":[178],"2-10":[179],"years":[180],"old":[181],"positive).":[183],"A":[184],"significant":[185],"difference":[186],"noted":[188],"average":[191],"infiltrations":[195],"two":[204],"groups":[205],"(P":[207],"less":[208],"than":[209],"0.001).":[210],"results":[212],"appear":[213],"indicate":[215],"that":[216],"adequate":[218],"intake":[220],"necessary":[222],"normal":[224],"retarded":[225],"response.":[227],"molecular":[229],"which":[232],"increases":[234],"still":[238],"decided.":[241]},"counts_by_year":[{"year":2017,"cited_by_count":2},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}