{"id":"https://openalex.org/W793471807","doi":null,"title":"The association of nutritional status and other lifestyle factors on human papillomavirus viral load","display_name":"The association of nutritional status and other lifestyle factors on human papillomavirus viral load","publication_year":2003,"publication_date":"2003-01-01","ids":{"openalex":"https://openalex.org/W793471807","mag":"793471807"},"language":"en","primary_location":{"id":"pmh:oai:repository.arizona.edu:10150/289972","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10150/289972","pdf_url":null,"source":{"id":"https://openalex.org/S4306400271","display_name":"UA Campus Repository (The University of Arizona)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I138006243","host_organization_name":"University of Arizona","host_organization_lineage":["https://openalex.org/I138006243"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Dissertation-Reproduction (electronic)"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046487725","display_name":"Roberto Flores-Munguia","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Roberto Flores-Munguia","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5046487725"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10146","display_name":"Cervical Cancer and HPV Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10146","display_name":"Cervical Cancer and HPV Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/human-papillomavirus","display_name":"human papillomavirus","score":0.9890000224113464},{"id":"https://openalex.org/keywords/viral-load","display_name":"viral load","score":0.7940000295639038},{"id":"https://openalex.org/keywords/nutritional-status","display_name":"nutritional status","score":0.7910000085830688},{"id":"https://openalex.org/keywords/cervical-intraepithelial-neoplasia","display_name":"cervical intraepithelial neoplasia","score":0.9200000166893005},{"id":"https://openalex.org/keywords/cervical-cancer","display_name":"cervical cancer","score":0.699999988079071},{"id":"https://openalex.org/keywords/persistent-hpv-infection","display_name":"persistent HPV infection","score":0.6769999861717224},{"id":"https://openalex.org/keywords/carotenoids","display_name":"carotenoids","score":0.7200000286102295},{"id":"https://openalex.org/keywords/tocopherols","display_name":"tocopherols","score":0.9559999704360962},{"id":"https://openalex.org/keywords/antioxidants","display_name":"antioxidants","score":0.6460000276565552},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.9819999933242798},{"id":"https://openalex.org/keywords/lifestyle-factors","display_name":"lifestyle factors","score":0.5820000171661377}],"concepts":[{"id":"https://openalex.org/C2994532551","wikidata":"https://www.wikidata.org/wiki/Q184627","display_name":"Human papillomavirus","level":2,"score":0.63765549659729},{"id":"https://openalex.org/C142853389","wikidata":"https://www.wikidata.org/wiki/Q744778","display_name":"Association (psychology)","level":2,"score":0.6129641532897949},{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.43987327814102173},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.439857542514801},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4170922636985779},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.3537752330303192},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.30442261695861816},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.24267414212226868},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.23554518818855286},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.19234785437583923},{"id":"https://openalex.org/C542102704","wikidata":"https://www.wikidata.org/wiki/Q183257","display_name":"Psychotherapist","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:repository.arizona.edu:10150/289972","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10150/289972","pdf_url":null,"source":{"id":"https://openalex.org/S4306400271","display_name":"UA Campus Repository (The University of Arizona)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I138006243","host_organization_name":"University of Arizona","host_organization_lineage":["https://openalex.org/I138006243"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Dissertation-Reproduction (electronic)"},{"id":"mag:793471807","doi":null,"is_oa":false,"landing_page_url":"https://arizona.openrepository.com/handle/10150/289972","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":181,"referenced_works":["https://openalex.org/W60523107","https://openalex.org/W108835801","https://openalex.org/W112760471","https://openalex.org/W115732276","https://openalex.org/W151092707","https://openalex.org/W162980116","https://openalex.org/W166172389","https://openalex.org/W183254587","https://openalex.org/W217511437","https://openalex.org/W303337234","https://openalex.org/W1266602514","https://openalex.org/W1505967068","https://openalex.org/W1507147384","https://openalex.org/W1518721136","https://openalex.org/W1529992354","https://openalex.org/W1540356264","https://openalex.org/W1561718910","https://openalex.org/W1575377264","https://openalex.org/W1577403013","https://openalex.org/W1603751017","https://openalex.org/W1605302322","https://openalex.org/W1609870932","https://openalex.org/W1643155728","https://openalex.org/W1675517407","https://openalex.org/W1828182586","https://openalex.org/W1901952501","https://openalex.org/W1905451881","https://openalex.org/W1931438463","https://openalex.org/W1947425084","https://openalex.org/W1953661334","https://openalex.org/W1959165312","https://openalex.org/W1965718518","https://openalex.org/W1968383325","https://openalex.org/W1971660947","https://openalex.org/W1972313158","https://openalex.org/W1975924701","https://openalex.org/W1976457795","https://openalex.org/W1976756980","https://openalex.org/W1977675750","https://openalex.org/W1977934371","https://openalex.org/W1977942351","https://openalex.org/W1979212917","https://openalex.org/W1980247821","https://openalex.org/W1983043261","https://openalex.org/W1984833080","https://openalex.org/W1986169988","https://openalex.org/W1987235414","https://openalex.org/W1987453246","https://openalex.org/W1988321634","https://openalex.org/W1991490744","https://openalex.org/W1994873916","https://openalex.org/W1996176524","https://openalex.org/W1997600127","https://openalex.org/W1998947396","https://openalex.org/W2001328903","https://openalex.org/W2006019758","https://openalex.org/W2006652805","https://openalex.org/W2009080092","https://openalex.org/W2009334997","https://openalex.org/W2009588836","https://openalex.org/W2012603529","https://openalex.org/W2013884760","https://openalex.org/W2016084390","https://openalex.org/W2019032733","https://openalex.org/W2019618500","https://openalex.org/W2023524643","https://openalex.org/W2025017506","https://openalex.org/W2026712887","https://openalex.org/W2027190423","https://openalex.org/W2028967730","https://openalex.org/W2029030998","https://openalex.org/W2029369170","https://openalex.org/W2032236621","https://openalex.org/W2032263275","https://openalex.org/W2032725237","https://openalex.org/W2035591488","https://openalex.org/W2038215491","https://openalex.org/W2038423155","https://openalex.org/W2038500217","https://openalex.org/W2040568824","https://openalex.org/W2040605721","https://openalex.org/W2041246059","https://openalex.org/W2051471929","https://openalex.org/W2052164494","https://openalex.org/W2052175020","https://openalex.org/W2052429195","https://openalex.org/W2054407949","https://openalex.org/W2055703143","https://openalex.org/W2056362005","https://openalex.org/W2056564646","https://openalex.org/W2059072983","https://openalex.org/W2059326135","https://openalex.org/W2060786724","https://openalex.org/W2062836204","https://openalex.org/W2063209931","https://openalex.org/W2063642597","https://openalex.org/W2063857788","https://openalex.org/W2066037962","https://openalex.org/W2066935713","https://openalex.org/W2068797155","https://openalex.org/W2072667169","https://openalex.org/W2074888068","https://openalex.org/W2081122945","https://openalex.org/W2083658994","https://openalex.org/W2084373954","https://openalex.org/W2085208129","https://openalex.org/W2087329824","https://openalex.org/W2087907584","https://openalex.org/W2090025458","https://openalex.org/W2090280060","https://openalex.org/W2090289097","https://openalex.org/W2093901599","https://openalex.org/W2093906223","https://openalex.org/W2094555201","https://openalex.org/W2094581205","https://openalex.org/W2094662417","https://openalex.org/W2096445237","https://openalex.org/W2096478290","https://openalex.org/W2098595283","https://openalex.org/W2098925859","https://openalex.org/W2106476914","https://openalex.org/W2106962073","https://openalex.org/W2107815610","https://openalex.org/W2108119284","https://openalex.org/W2113152942","https://openalex.org/W2113364001","https://openalex.org/W2114813165","https://openalex.org/W2119862041","https://openalex.org/W2120863479","https://openalex.org/W2124263641","https://openalex.org/W2127576059","https://openalex.org/W2128737857","https://openalex.org/W2129106917","https://openalex.org/W2129745672","https://openalex.org/W2130320491","https://openalex.org/W2134410409","https://openalex.org/W2134528790","https://openalex.org/W2137192946","https://openalex.org/W2137715932","https://openalex.org/W2138521238","https://openalex.org/W2138746759","https://openalex.org/W2139573924","https://openalex.org/W2139874928","https://openalex.org/W2141195019","https://openalex.org/W2141196337","https://openalex.org/W2142033071","https://openalex.org/W2142054229","https://openalex.org/W2145119829","https://openalex.org/W2145704650","https://openalex.org/W2145907568","https://openalex.org/W2146697637","https://openalex.org/W2147235018","https://openalex.org/W2150086028","https://openalex.org/W2150481857","https://openalex.org/W2151164686","https://openalex.org/W2151892297","https://openalex.org/W2152202163","https://openalex.org/W2152349999","https://openalex.org/W2152820745","https://openalex.org/W2153342521","https://openalex.org/W2153350694","https://openalex.org/W2154115145","https://openalex.org/W2160110525","https://openalex.org/W2161342571","https://openalex.org/W2164578725","https://openalex.org/W2166666129","https://openalex.org/W2169183151","https://openalex.org/W2169767104","https://openalex.org/W2183740206","https://openalex.org/W2189040616","https://openalex.org/W2266890614","https://openalex.org/W2283472986","https://openalex.org/W2323652843","https://openalex.org/W2337028134","https://openalex.org/W2400563373","https://openalex.org/W2405087813","https://openalex.org/W2405840674","https://openalex.org/W2413997174","https://openalex.org/W2460269057","https://openalex.org/W2481961322","https://openalex.org/W2526241552"],"related_works":["https://openalex.org/W2040605721","https://openalex.org/W649773789","https://openalex.org/W2266890614","https://openalex.org/W2013403745","https://openalex.org/W4413370753","https://openalex.org/W2032290422","https://openalex.org/W2068292819","https://openalex.org/W2269195265","https://openalex.org/W2570988022","https://openalex.org/W349333138"],"abstract_inverted_index":{"Infection":[0],"with":[1,71,86,120,150,188,201,216,246,257],"mucosotropic":[2],"human":[3],"papillomavirus":[4],"(HPV)":[5],"is":[6],"necessary":[7],"but":[8],"not":[9],"sufficient":[10],"for":[11,263,302],"development":[12],"of":[13,25,35,44,57,67,93,112,136,145,153,184,197,204,227,284],"cervical":[14,21,45,58,68,121,137,157,217],"intraepithelial":[15,158],"lesions":[16],"and":[17,30,38,90,134,155,167,208,230,241,250,273],"its":[18],"ultimate":[19],"stage":[20],"cancer.":[22,59,122],"The":[23],"majority":[24],"HPV":[26,73,87,114,147,185,198,288,292,303],"infections":[27,36],"are":[28,52],"transient":[29],"only":[31],"a":[32,102,142,181,242,282,299],"minor":[33],"proportion":[34],"persist":[37],"progress":[39],"to":[40,108,127],"more":[41],"advanced":[42],"stages":[43],"dysplasia.":[46,138],"This":[47,123],"suggests":[48],"that":[49],"other":[50],"factors":[51,78],"involved":[53,210],"in":[54,211,287],"the":[55,129,195,202],"pathogenesis":[56],"Previous":[60],"studies":[61],"have":[62,100],"determined":[63],"an":[64,224],"increased":[65,151],"risk":[66,92,135,152],"cancer":[69],"associated":[70,85,119,215],"high":[72,146],"viral":[74,110,132,148,186,199,220,228,259,289,293],"load.":[75,290],"Other":[76],"host":[77],"such":[79],"as":[80,298],"nutritional":[81],"status":[82],"may":[83,295],"be":[84,296],"infection":[88],"persistence":[89],"higher":[91],"developing":[94],"neoplasia.":[95],"In":[96,191],"this":[97,178,279],"study,":[98],"we":[99,193],"developed":[101],"real-time":[103],"polymerase":[104],"chain":[105],"reaction":[106],"assay":[107],"quantitate":[109],"burden":[111,229],"eight":[113],"types":[115],"most":[116],"frequently":[117],"found":[118],"methodology":[124],"was":[125,261],"used":[126],"study":[128,179,222,280],"association":[130,144,196,226,245,256],"between":[131],"load":[133,149,187,200,260,294],"Our":[139,219],"results":[140],"indicate":[141],"strong":[143],"low-grade":[154],"high-grade":[156],"neoplasia":[159],"(OR":[160],"=":[161,165,169,173],"47.7,":[162],"95%":[163,171],"CI":[164,172],"17.04-133.58;":[166],"OR":[168],"58.05,":[170],"18.43-182.89,":[174],"respectively).":[175],"Findings":[176,277],"from":[177,278],"suggest":[180,281],"linear":[182],"increase":[183],"cytological":[189],"grade.":[190],"addition,":[192],"studied":[194],"concentration":[203],"circulating":[205,231,285],"antioxidant":[206],"nutrients":[207,209,286],"DNA":[212],"methylation":[213],"previously":[214],"carcinogenesis.":[218],"load-nutrient":[221],"identified":[223],"inverse":[225],"trans-lycopene":[232],"(p,":[233,236,239,248,252,265,268,271,275],"0.0375),":[234],"\u03b2-cryptoxanthin":[235],"0.0494),":[237],"trans-\u03b2-carotene":[238],"0.0105),":[240],"possible":[243],"protective":[244],"cis-lycopene":[247],"0.0544)":[249],"lutein":[251],"0.0977).":[253],"A":[254],"direct":[255],"total":[258],"observed":[262],"\u03b1-carotene":[264],"0.0038),":[266],"\u03b1-tocopherol":[267],"0.0207),":[269],"\u03b3-tocopherol":[270],"0.0288),":[272],"\u03b4-tocopherol":[274],"0.0446).":[276],"role":[283],"Overall,":[291],"useful":[297],"surrogate":[300],"biomarker":[301],"persistence.":[304]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-06-24T00:00:00"}
