{"id":"https://openalex.org/W792093786","doi":"https://doi.org/10.1016/j.ijpara.2015.05.003","title":"RNA interference in adult Ascaris suum \u2013 an opportunity for the development of a functional genomics platform that supports organism-, tissue- and cell-based biology in a nematode parasite","display_name":"RNA interference in adult Ascaris suum \u2013 an opportunity for the development of a functional genomics platform that supports organism-, tissue- and cell-based biology in a nematode parasite","publication_year":2015,"publication_date":"2015-07-05","ids":{"openalex":"https://openalex.org/W792093786","doi":"https://doi.org/10.1016/j.ijpara.2015.05.003","mag":"792093786","pmid":"https://pubmed.ncbi.nlm.nih.gov/26149642","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4563943"},"language":"en","primary_location":{"id":"doi:10.1016/j.ijpara.2015.05.003","doi":"https://doi.org/10.1016/j.ijpara.2015.05.003","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ijpara.2015.05.003","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0020751915001654/pdf","source":{"id":"https://openalex.org/S163169856","display_name":"International Journal for Parasitology","issn_l":"0020-7519","issn":["0020-7519","1879-0135"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal for Parasitology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.sciencedirect.com/science/article/pii/S0020751915001654/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040193738","display_name":"Ciaran J. McCoy","orcid":"https://orcid.org/0009-0001-0843-5952","observed_orcids":["https://orcid.org/0009-0001-0843-5952"]},"institutions":[{"id":"https://openalex.org/I126231945","display_name":"Queen's University Belfast","ror":"https://ror.org/00hswnk62","country_code":"GB","type":"education","lineage":["https://openalex.org/I126231945"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ciaran J. McCoy","raw_affiliation_strings":["Parasitology, Institute for Global Food Security, School of Biological Sciences, Queen's University Belfast, Belfast BT9 7BL, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Parasitology, Institute for Global Food Security, School of Biological Sciences, Queen's University Belfast, Belfast BT9 7BL, UK","institution_ids":["https://openalex.org/I126231945"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017591854","display_name":"Neil D. Warnock","orcid":"https://orcid.org/0009-0001-0651-5289","observed_orcids":["https://orcid.org/0009-0001-0651-5289"]},"institutions":[{"id":"https://openalex.org/I126231945","display_name":"Queen's University Belfast","ror":"https://ror.org/00hswnk62","country_code":"GB","type":"education","lineage":["https://openalex.org/I126231945"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Neil D. Warnock","raw_affiliation_strings":["Parasitology, Institute for Global Food Security, School of Biological Sciences, Queen's University Belfast, Belfast BT9 7BL, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Parasitology, Institute for Global Food Security, School of Biological Sciences, Queen's University Belfast, Belfast BT9 7BL, UK","institution_ids":["https://openalex.org/I126231945"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029022107","display_name":"Louise E. Atkinson","orcid":"https://orcid.org/0000-0002-5184-2676","observed_orcids":["https://orcid.org/0000-0002-5184-2676"]},"institutions":[{"id":"https://openalex.org/I126231945","display_name":"Queen's University Belfast","ror":"https://ror.org/00hswnk62","country_code":"GB","type":"education","lineage":["https://openalex.org/I126231945"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Louise E. Atkinson","raw_affiliation_strings":["Parasitology, Institute for Global Food Security, School of Biological Sciences, Queen's University Belfast, Belfast BT9 7BL, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Parasitology, Institute for Global Food Security, School of Biological Sciences, Queen's University Belfast, Belfast BT9 7BL, UK","institution_ids":["https://openalex.org/I126231945"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022200259","display_name":"Erwan Atcheson","orcid":"https://orcid.org/0000-0002-8111-1516","observed_orcids":["https://orcid.org/0000-0002-8111-1516"]},"institutions":[{"id":"https://openalex.org/I126231945","display_name":"Queen's University Belfast","ror":"https://ror.org/00hswnk62","country_code":"GB","type":"education","lineage":["https://openalex.org/I126231945"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Erwan Atcheson","raw_affiliation_strings":["Parasitology, Institute for Global Food Security, School of Biological Sciences, Queen's University Belfast, Belfast BT9 7BL, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Parasitology, Institute for Global Food Security, School of Biological Sciences, Queen's University Belfast, Belfast BT9 7BL, UK","institution_ids":["https://openalex.org/I126231945"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033749081","display_name":"Richard J. Martin","orcid":"https://orcid.org/0000-0003-2422-1847","observed_orcids":["https://orcid.org/0000-0003-2422-1847"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard J. Martin","raw_affiliation_strings":["Department of Biomedical Sciences, Iowa State University, Ames, IA 50011, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, Iowa State University, Ames, IA 50011, USA","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002068300","display_name":"Alan Patrick Robertson","orcid":"https://orcid.org/0000-0002-7980-1139","observed_orcids":["https://orcid.org/0000-0002-7980-1139"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alan P. Robertson","raw_affiliation_strings":["Department of Biomedical Sciences, Iowa State University, Ames, IA 50011, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, Iowa State University, Ames, IA 50011, USA","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063393401","display_name":"Aaron G. Maule","orcid":"https://orcid.org/0000-0003-0862-2667","observed_orcids":["https://orcid.org/0000-0003-0862-2667"]},"institutions":[{"id":"https://openalex.org/I126231945","display_name":"Queen's University Belfast","ror":"https://ror.org/00hswnk62","country_code":"GB","type":"education","lineage":["https://openalex.org/I126231945"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Aaron G. Maule","raw_affiliation_strings":["Parasitology, Institute for Global Food Security, School of Biological Sciences, Queen's University Belfast, Belfast BT9 7BL, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Parasitology, Institute for Global Food Security, School of Biological Sciences, Queen's University Belfast, Belfast BT9 7BL, UK","institution_ids":["https://openalex.org/I126231945"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102918884","display_name":"Nikki J. Marks","orcid":"https://orcid.org/0000-0002-9598-4115","observed_orcids":["https://orcid.org/0000-0002-9598-4115"]},"institutions":[{"id":"https://openalex.org/I126231945","display_name":"Queen's University Belfast","ror":"https://ror.org/00hswnk62","country_code":"GB","type":"education","lineage":["https://openalex.org/I126231945"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nikki J. Marks","raw_affiliation_strings":["Parasitology, Institute for Global Food Security, School of Biological Sciences, Queen's University Belfast, Belfast BT9 7BL, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Parasitology, Institute for Global Food Security, School of Biological Sciences, Queen's University Belfast, Belfast BT9 7BL, UK","institution_ids":["https://openalex.org/I126231945"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042189168","display_name":"Angela Mousley","orcid":"https://orcid.org/0000-0001-7373-912X","observed_orcids":["https://orcid.org/0000-0001-7373-912X"]},"institutions":[{"id":"https://openalex.org/I126231945","display_name":"Queen's University Belfast","ror":"https://ror.org/00hswnk62","country_code":"GB","type":"education","lineage":["https://openalex.org/I126231945"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Angela Mousley","raw_affiliation_strings":["Parasitology, Institute for Global Food Security, School of Biological Sciences, Queen's University Belfast, Belfast BT9 7BL, UK. Electronic address: a.mousley@qub.ac.uk","Queen's University Belfast"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Parasitology, Institute for Global Food Security, School of Biological Sciences, Queen's University Belfast, Belfast BT9 7BL, UK. Electronic address: a.mousley@qub.ac.uk","institution_ids":["https://openalex.org/I126231945"]},{"raw_affiliation_string":"Queen's University Belfast","institution_ids":["https://openalex.org/I126231945"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5042189168"],"corresponding_institution_ids":["https://openalex.org/I126231945"],"apc_list":{"value":2880,"currency":"USD","value_usd":2880},"apc_paid":{"value":2880,"currency":"USD","value_usd":2880},"fwci":7.4338,"has_fulltext":true,"cited_by_count":48,"citation_normalized_percentile":{"value":0.97309797,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"45","issue":"11","first_page":"673","last_page":"678"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11074","display_name":"Helminth infection and control","score":0.9247999787330627,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11074","display_name":"Helminth infection and control","score":0.9247999787330627,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10695","display_name":"Parasites and Host Interactions","score":0.06310000270605087,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11179","display_name":"Nematode management and characterization studies","score":0.008500000461935997,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rna-interference","display_name":"RNA interference","score":0.9860000014305115},{"id":"https://openalex.org/keywords/ascaris-suum","display_name":"Ascaris suum","score":0.9980000257492065},{"id":"https://openalex.org/keywords/parasitic-nematodes","display_name":"parasitic nematodes","score":0.746999979019165},{"id":"https://openalex.org/keywords/functional-genomics","display_name":"functional genomics","score":0.8320000171661377},{"id":"https://openalex.org/keywords/drug-target-validation","display_name":"drug target validation","score":0.7360000014305115},{"id":"https://openalex.org/keywords/zoonotic-parasites","display_name":"zoonotic parasites","score":0.6620000004768372}],"concepts":[{"id":"https://openalex.org/C2779845534","wikidata":"https://www.wikidata.org/wiki/Q2062253","display_name":"Ascaris suum","level":3,"score":0.9541878700256348},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8931178450584412},{"id":"https://openalex.org/C166703698","wikidata":"https://www.wikidata.org/wiki/Q201993","display_name":"RNA interference","level":4,"score":0.7996083498001099},{"id":"https://openalex.org/C137858568","wikidata":"https://www.wikidata.org/wiki/Q7239","display_name":"Organism","level":2,"score":0.7092301845550537},{"id":"https://openalex.org/C161078062","wikidata":"https://www.wikidata.org/wiki/Q1068690","display_name":"Functional genomics","level":5,"score":0.6317571401596069},{"id":"https://openalex.org/C2778830712","wikidata":"https://www.wikidata.org/wiki/Q5185","display_name":"Nematode","level":2,"score":0.5282247066497803},{"id":"https://openalex.org/C19843653","wikidata":"https://www.wikidata.org/wiki/Q213907","display_name":"Model organism","level":3,"score":0.4974549114704132},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4629225730895996},{"id":"https://openalex.org/C2780492224","wikidata":"https://www.wikidata.org/wiki/Q310838","display_name":"Ascaris","level":3,"score":0.4570060968399048},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.38388872146606445},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.26384109258651733},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2544649839401245},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2391534149646759},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.20936059951782227},{"id":"https://openalex.org/C165901193","wikidata":"https://www.wikidata.org/wiki/Q3129936","display_name":"Helminths","level":2,"score":0.20707440376281738},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.14299696683883667},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.11719855666160583}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017165","descriptor_name":"Ascaris suum","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D034622","descriptor_name":"RNA Interference","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1016/j.ijpara.2015.05.003","doi":"https://doi.org/10.1016/j.ijpara.2015.05.003","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ijpara.2015.05.003","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0020751915001654/pdf","source":{"id":"https://openalex.org/S163169856","display_name":"International Journal for Parasitology","issn_l":"0020-7519","issn":["0020-7519","1879-0135"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal for Parasitology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3556536","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4563943","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4563943","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4563943","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Parasitol","raw_type":"Text"},{"id":"pmid:26149642","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26149642","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal for parasitology","raw_type":"Journal Article"},{"id":"pmh:oai:pure.qub.ac.uk/portal:openaire/ca17eee0-d063-4fad-982f-827073028000","doi":null,"is_oa":true,"landing_page_url":"https://pure.qub.ac.uk/en/publications/ca17eee0-d063-4fad-982f-827073028000","pdf_url":"https://pureadmin.qub.ac.uk/ws/files/16644581/Rna.pdf","source":{"id":"https://openalex.org/S4306402319","display_name":"Research Portal (Queen's University Belfast)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I126231945","host_organization_name":"Queen's University Belfast","host_organization_lineage":["https://openalex.org/I126231945"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"McCoy, C J, Warnock, N D, Atkinson, L E, Atcheson, E, Martin, R J, Robertson, A P, Maule, A G, Marks, N & Mousley, A 2015, 'RNA interference in adult Ascaris suum - an opportunity for the development of a functional genomics platform that supports organism-, tissue- and cell-based biology in a nematode parasite', International Journal for Parasitology, vol. 45, no. 11, pp. 673-678. https://doi.org/10.1016/j.ijpara.2015.05.003","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1016/j.ijpara.2015.05.003","doi":"https://doi.org/10.1016/j.ijpara.2015.05.003","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ijpara.2015.05.003","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0020751915001654/pdf","source":{"id":"https://openalex.org/S163169856","display_name":"International Journal for Parasitology","issn_l":"0020-7519","issn":["0020-7519","1879-0135"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal for Parasitology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6000000238418579}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2220325819","display_name":"ASCARIS SUUM, A NEW FUNCTIONAL GENOMICS PLATFORM FOR NEMATODE PARASITES","funder_award_id":"BB/M010392/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G286866916","display_name":"Pharmacological Diversity of nAChRs in Clade III Nematodes: Brugia malayi","funder_award_id":"R01AI047194","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G5667337229","display_name":"FLPing around aids behavioural adaptability in nematodes","funder_award_id":"BB/H019472/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320311563","display_name":"British Society For Parasitology","ror":"https://ror.org/04bjtaq20"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332167","display_name":"Directorate for Biological Sciences","ror":"https://ror.org/001xhss06"},{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W792093786.pdf","grobid_xml":"https://content.openalex.org/works/W792093786.grobid-xml"},"referenced_works_count":28,"referenced_works":["https://openalex.org/W1534366773","https://openalex.org/W1964887411","https://openalex.org/W1989706787","https://openalex.org/W2002202509","https://openalex.org/W2019539444","https://openalex.org/W2020639485","https://openalex.org/W2024454793","https://openalex.org/W2025767497","https://openalex.org/W2029125407","https://openalex.org/W2030785900","https://openalex.org/W2046649749","https://openalex.org/W2048407401","https://openalex.org/W2048858568","https://openalex.org/W2055032691","https://openalex.org/W2061103226","https://openalex.org/W2087587061","https://openalex.org/W2108138763","https://openalex.org/W2108244474","https://openalex.org/W2122546565","https://openalex.org/W2123983056","https://openalex.org/W2136579622","https://openalex.org/W2139902443","https://openalex.org/W2141765318","https://openalex.org/W2142305917","https://openalex.org/W2155159152","https://openalex.org/W2168549429","https://openalex.org/W2482376982","https://openalex.org/W4252894290"],"related_works":["https://openalex.org/W7066857149","https://openalex.org/W2061103226","https://openalex.org/W2030785900","https://openalex.org/W2590102073","https://openalex.org/W1976394015","https://openalex.org/W3043951911","https://openalex.org/W2016795682","https://openalex.org/W2041797719","https://openalex.org/W1820461576","https://openalex.org/W2025767497"],"abstract_inverted_index":{"The":[0],"sustainable":[1],"control":[2],"of":[3,10,26,33,70,100],"animal":[4],"parasitic":[5],"nematodes":[6],"requires":[7],"the":[8,24,31,65],"development":[9],"efficient":[11],"functional":[12],"genomics":[13],"platforms":[14],"to":[15,82,92],"facilitate":[16],"target":[17,94],"validation":[18,32,95],"and":[19,49,63,68,87],"enhance":[20,93],"anthelmintic":[21],"discovery.":[22],"Unfortunately,":[23],"utility":[25],"RNA":[27],"interference":[28],"(RNAi)":[29],"for":[30,97],"novel":[34],"drug":[35],"targets":[36],"in":[37],"nematode":[38,98],"parasites":[39,99],"remains":[40],"problematic.":[41],"Ascaris":[42],"suum":[43,59],"is":[44,60],"an":[45],"important":[46],"veterinary":[47],"parasite":[48],"a":[50,79],"zoonotic":[51],"pathogen.":[52],"Here":[53],"we":[54],"show":[55],"that":[56],"adult":[57],"A.":[58],"RNAi":[61,71],"competent,":[62],"highlight":[64],"induction,":[66],"spread":[67],"consistency":[69],"across":[72],"multiple":[73],"tissue":[74],"types.":[75],"This":[76],"platform":[77],"provides":[78],"new":[80],"opportunity":[81],"undertake":[83],"whole":[84],"organism-,":[85],"tissue-":[86],"cell-level":[88],"gene":[89],"function":[90],"studies":[91],"processes":[96],"veterinary/medical":[101],"significance.":[102]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}