{"id":"https://openalex.org/W791036753","doi":null,"title":"Cholinergic Modulation of GABAergic Inhibition Dynamics In The Striatum","display_name":"Cholinergic Modulation of GABAergic Inhibition Dynamics In The Striatum","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W791036753","mag":"791036753"},"language":"en","primary_location":{"id":"pmh:oai:repository.library.georgetown.edu:10822/710037","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10822/710037","pdf_url":null,"source":{"id":"https://openalex.org/S4306402467","display_name":"DigitalGeorgetown (Georgetown University Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210145449","host_organization_name":"Center for Security and Emerging Technology","host_organization_lineage":["https://openalex.org/I4210145449"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Pharmacology","raw_type":"thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103625291","display_name":"Ruixi Luo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Ruixi Luo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5103625291"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9800000190734863,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9800000190734863,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.011099999770522118,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10919","display_name":"Deep Brain Stimulation and Movement Disorders","score":0.004000000189989805,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cholinergic-modulation","display_name":"cholinergic modulation","score":0.8659999966621399},{"id":"https://openalex.org/keywords/gabaergic-inhibition","display_name":"GABAergic inhibition","score":0.9760000109672546},{"id":"https://openalex.org/keywords/striatum","display_name":"striatum","score":0.9919999837875366},{"id":"https://openalex.org/keywords/medium-spiny-neurons","display_name":"medium spiny neurons","score":0.9980000257492065},{"id":"https://openalex.org/keywords/dopamine-d1-receptor","display_name":"dopamine D1 receptor","score":0.7139999866485596},{"id":"https://openalex.org/keywords/dopamine-d2-receptor","display_name":"dopamine D2 receptor","score":0.9990000128746033},{"id":"https://openalex.org/keywords/gaba-release","display_name":"GABA release","score":0.8880000114440918},{"id":"https://openalex.org/keywords/striatal-interneurons","display_name":"striatal interneurons","score":0.6140000224113464}],"concepts":[{"id":"https://openalex.org/C2780062018","wikidata":"https://www.wikidata.org/wiki/Q1319792","display_name":"Striatum","level":3,"score":0.7579642534255981},{"id":"https://openalex.org/C2779177108","wikidata":"https://www.wikidata.org/wiki/Q18356742","display_name":"GABAergic","level":3,"score":0.7475558519363403},{"id":"https://openalex.org/C22885893","wikidata":"https://www.wikidata.org/wiki/Q4862743","display_name":"Cholinergic","level":2,"score":0.7252258062362671},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6649430990219116},{"id":"https://openalex.org/C123079801","wikidata":"https://www.wikidata.org/wiki/Q750240","display_name":"Modulation (music)","level":2,"score":0.4943368434906006},{"id":"https://openalex.org/C145912823","wikidata":"https://www.wikidata.org/wiki/Q113558","display_name":"Dynamics (music)","level":2,"score":0.4779367744922638},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.2747461199760437},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.18678244948387146},{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.11920753121376038},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.10220104455947876},{"id":"https://openalex.org/C19417346","wikidata":"https://www.wikidata.org/wiki/Q7922","display_name":"Pedagogy","level":1,"score":0.0},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:repository.library.georgetown.edu:10822/710037","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10822/710037","pdf_url":null,"source":{"id":"https://openalex.org/S4306402467","display_name":"DigitalGeorgetown (Georgetown University Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210145449","host_organization_name":"Center for Security and Emerging Technology","host_organization_lineage":["https://openalex.org/I4210145449"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Pharmacology","raw_type":"thesis"},{"id":"mag:791036753","doi":null,"is_oa":false,"landing_page_url":"https://repository.library.georgetown.edu/bitstream/10822/710037/1/Luo_georgetown_0076D_12718.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S2764685317","display_name":"Georgetown University-Graduate School of Arts & Sciences","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4323970070","host_organization_name":"Georgetown University","host_organization_lineage":["https://openalex.org/P4323970070"],"host_organization_lineage_names":["Georgetown University"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Georgetown University-Graduate School of Arts & Sciences","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.4000000059604645}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":108,"referenced_works":["https://openalex.org/W633088308","https://openalex.org/W657526032","https://openalex.org/W1511312105","https://openalex.org/W1526327880","https://openalex.org/W1550227666","https://openalex.org/W1563966782","https://openalex.org/W1594941540","https://openalex.org/W1824285989","https://openalex.org/W1885050361","https://openalex.org/W1892249233","https://openalex.org/W1893053185","https://openalex.org/W1910271824","https://openalex.org/W1931044993","https://openalex.org/W1966698116","https://openalex.org/W1969392675","https://openalex.org/W1973052095","https://openalex.org/W1973540764","https://openalex.org/W1973747047","https://openalex.org/W1986641407","https://openalex.org/W1995202163","https://openalex.org/W1995454338","https://openalex.org/W1995493882","https://openalex.org/W1996449721","https://openalex.org/W2002363647","https://openalex.org/W2006457780","https://openalex.org/W2007467910","https://openalex.org/W2008706955","https://openalex.org/W2011154084","https://openalex.org/W2011857818","https://openalex.org/W2014271878","https://openalex.org/W2014706755","https://openalex.org/W2015040491","https://openalex.org/W2016321438","https://openalex.org/W2017400430","https://openalex.org/W2019419655","https://openalex.org/W2020812209","https://openalex.org/W2021194790","https://openalex.org/W2021454300","https://openalex.org/W2022470580","https://openalex.org/W2023132644","https://openalex.org/W2025058104","https://openalex.org/W2029215893","https://openalex.org/W2032284808","https://openalex.org/W2032471499","https://openalex.org/W2033366759","https://openalex.org/W2040720903","https://openalex.org/W2044632071","https://openalex.org/W2044866059","https://openalex.org/W2046987765","https://openalex.org/W2048876704","https://openalex.org/W2050173449","https://openalex.org/W2050455764","https://openalex.org/W2052070189","https://openalex.org/W2052163800","https://openalex.org/W2052714236","https://openalex.org/W2058719793","https://openalex.org/W2059725343","https://openalex.org/W2061947653","https://openalex.org/W2062186332","https://openalex.org/W2063370969","https://openalex.org/W2067332426","https://openalex.org/W2069441590","https://openalex.org/W2072308972","https://openalex.org/W2074728660","https://openalex.org/W2075994330","https://openalex.org/W2082128892","https://openalex.org/W2083623577","https://openalex.org/W2083977571","https://openalex.org/W2087738283","https://openalex.org/W2091486815","https://openalex.org/W2092762167","https://openalex.org/W2094771978","https://openalex.org/W2096240481","https://openalex.org/W2100231995","https://openalex.org/W2101036582","https://openalex.org/W2104135721","https://openalex.org/W2105294045","https://openalex.org/W2105987091","https://openalex.org/W2108502510","https://openalex.org/W2112196515","https://openalex.org/W2115131555","https://openalex.org/W2116251480","https://openalex.org/W2118021908","https://openalex.org/W2118830830","https://openalex.org/W2121237571","https://openalex.org/W2124659766","https://openalex.org/W2124793944","https://openalex.org/W2125018051","https://openalex.org/W2125277337","https://openalex.org/W2127183925","https://openalex.org/W2129962758","https://openalex.org/W2134766199","https://openalex.org/W2135929777","https://openalex.org/W2136267239","https://openalex.org/W2137471600","https://openalex.org/W2139053364","https://openalex.org/W2139495058","https://openalex.org/W2141716990","https://openalex.org/W2149367136","https://openalex.org/W2151685070","https://openalex.org/W2157984060","https://openalex.org/W2158256695","https://openalex.org/W2158420012","https://openalex.org/W2159423248","https://openalex.org/W2166814887","https://openalex.org/W2167095271","https://openalex.org/W2171464354","https://openalex.org/W2173794755"],"related_works":["https://openalex.org/W3101289222","https://openalex.org/W2746738354","https://openalex.org/W2413087073","https://openalex.org/W1984945304","https://openalex.org/W2098068501","https://openalex.org/W2068755196","https://openalex.org/W2088743084","https://openalex.org/W2611535000","https://openalex.org/W3143188844","https://openalex.org/W2012350066"],"abstract_inverted_index":{"The":[0],"striatum":[1],"contains":[2],"medium":[3],"spiny":[4],"neurons":[5],"(MSNs)":[6],"classified":[7],"by":[8,34],"their":[9],"axonal":[10],"projection":[11],"and":[12,19,22],"expression":[13],"of":[14],"dopamine":[15],"receptors":[16],"into":[17],"D1+":[18],"D2+":[20],"MSNs;":[21],"interneurons":[23,28],"including":[24],"choline":[25],"acetyltransferase":[26],"expressing":[27],"(ChAT+)":[29],"that":[30],"influence":[31],"MSN":[32],"activity":[33],"triggering":[35],"GABA":[36],"release.":[37],"Here,":[38],"I":[39],"identify":[40],"the":[41],"potential":[42]},"counts_by_year":[],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2016-06-24T00:00:00"}