{"id":"https://openalex.org/W790533244","doi":null,"title":"Avalia\u00e7\u00e3o da atividade anti-inflamat\u00f3ria intestinal de Pfaffia glomerata (Spreng.) Pedersen","display_name":"Avalia\u00e7\u00e3o da atividade anti-inflamat\u00f3ria intestinal de Pfaffia glomerata (Spreng.) Pedersen","publication_year":2013,"publication_date":"2013-02-27","ids":{"openalex":"https://openalex.org/W790533244","mag":"790533244"},"language":"pt","primary_location":{"id":"pmh:oai:americanae.aecid.es:1728762","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11449/91643","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"reponame:Reposit\u00f3rio Institucional da UNESP","raw_type":"info:eu-repo/semantics/masterThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/11449/91643","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087269753","display_name":"Alexandre Tanimoto","orcid":"https://orcid.org/0000-0002-9768-8555","observed_orcids":["https://orcid.org/0000-0002-9768-8555"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Alexandre Tanimoto","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9768-8555","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5087269753"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11889","display_name":"Ginseng Biological Effects and Applications","score":0.6532999873161316,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11889","display_name":"Ginseng Biological Effects and Applications","score":0.6532999873161316,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.26809999346733093,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12657","display_name":"Phytochemistry Medicinal Plant Applications","score":0.030300000682473183,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pfaffia-glomerata","display_name":"Pfaffia glomerata","score":1.0},{"id":"https://openalex.org/keywords/brazilian-ginseng","display_name":"Brazilian ginseng","score":0.9179999828338623},{"id":"https://openalex.org/keywords/anti-inflammatory-activity","display_name":"anti-inflammatory activity","score":0.906000018119812},{"id":"https://openalex.org/keywords/inflammatory-bowel-disease","display_name":"inflammatory bowel disease","score":0.8700000047683716},{"id":"https://openalex.org/keywords/tnbs-induced-colitis","display_name":"TNBS-induced colitis","score":0.9359999895095825},{"id":"https://openalex.org/keywords/butanol-fraction","display_name":"butanol fraction","score":0.8420000076293945},{"id":"https://openalex.org/keywords/saponins","display_name":"saponins","score":0.968999981880188},{"id":"https://openalex.org/keywords/triterpenoids","display_name":"triterpenoids","score":0.9290000200271606},{"id":"https://openalex.org/keywords/20-hydroxyecdysone","display_name":"20-hydroxyecdysone","score":0.8539999723434448},{"id":"https://openalex.org/keywords/adaptogens","display_name":"adaptogens","score":0.8640000224113464},{"id":"https://openalex.org/keywords/myeloperoxidase","display_name":"myeloperoxidase","score":0.9089999794960022},{"id":"https://openalex.org/keywords/alkaline-phosphatase","display_name":"alkaline phosphatase","score":0.9980000257492065},{"id":"https://openalex.org/keywords/glutathione","display_name":"glutathione","score":0.968999981880188},{"id":"https://openalex.org/keywords/phytochemical-screening","display_name":"phytochemical screening","score":0.5690000057220459},{"id":"https://openalex.org/keywords/medicinal-plants","display_name":"medicinal plants","score":0.4480000138282776}],"concepts":[{"id":"https://openalex.org/C195475562","wikidata":"https://www.wikidata.org/wiki/Q1639139","display_name":"Phytochemical","level":2,"score":0.7950707674026489},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.6697743535041809},{"id":"https://openalex.org/C2778260677","wikidata":"https://www.wikidata.org/wiki/Q917447","display_name":"Inflammatory bowel disease","level":3,"score":0.5130907297134399},{"id":"https://openalex.org/C2779232237","wikidata":"https://www.wikidata.org/wiki/Q20817212","display_name":"Ginseng","level":3,"score":0.4971800148487091},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.44328951835632324},{"id":"https://openalex.org/C2776798904","wikidata":"https://www.wikidata.org/wiki/Q93978","display_name":"Antispasmodic","level":2,"score":0.4125581383705139},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.38962841033935547},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3211890161037445},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.1589716672897339},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.09770530462265015},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:oai:americanae.aecid.es:1728762","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11449/91643","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"reponame:Reposit\u00f3rio Institucional da UNESP","raw_type":"info:eu-repo/semantics/masterThesis"},{"id":"pmh:oai:repositorio.unesp.br:11449/91643","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11449/91643","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"instacron:UNESP","raw_type":"info:eu-repo/semantics/masterThesis"},{"id":"pmh:oai:acervodigital.unesp.br:11449/91643","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11449/91643","pdf_url":"http://hdl.handle.net/11449/91643","source":{"id":"https://openalex.org/S4306400256","display_name":"Acervo Digital da Universidade Estadual Paulista (Universidade Estadual Paulista)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210115194","host_organization_name":"Funda\u00e7\u00e3o para o Desenvolvimento da UNESP","host_organization_lineage":["https://openalex.org/I4210115194"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"outro"},{"id":"mag:790533244","doi":null,"is_oa":false,"landing_page_url":"http://repositorio.unesp.br/handle/11449/91643","pdf_url":null,"source":{"id":"https://openalex.org/S4210186100","display_name":"Aleph UCLA Undergraduate Research Journal for the Humanities and Social Sciences","issn_l":"2639-6440","issn":["2639-6440","2639-6459"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Aleph UCLA Undergraduate Research Journal for the Humanities and Social Sciences","raw_type":null}],"best_oa_location":{"id":"pmh:oai:americanae.aecid.es:1728762","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11449/91643","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"reponame:Reposit\u00f3rio Institucional da UNESP","raw_type":"info:eu-repo/semantics/masterThesis"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W790533244.pdf","grobid_xml":"https://content.openalex.org/works/W790533244.grobid-xml"},"referenced_works_count":86,"referenced_works":["https://openalex.org/W159222244","https://openalex.org/W279093606","https://openalex.org/W307279479","https://openalex.org/W1523941392","https://openalex.org/W1536246920","https://openalex.org/W1553784037","https://openalex.org/W1559903407","https://openalex.org/W1734901513","https://openalex.org/W1800250437","https://openalex.org/W1820107909","https://openalex.org/W1880062250","https://openalex.org/W1966010545","https://openalex.org/W1966882632","https://openalex.org/W1967461227","https://openalex.org/W1967659825","https://openalex.org/W1970815880","https://openalex.org/W1976827888","https://openalex.org/W1981245565","https://openalex.org/W1982478802","https://openalex.org/W1985374023","https://openalex.org/W1993678556","https://openalex.org/W1997127851","https://openalex.org/W1999161684","https://openalex.org/W2000984739","https://openalex.org/W2001167492","https://openalex.org/W2003583857","https://openalex.org/W2004608617","https://openalex.org/W2004870799","https://openalex.org/W2004994974","https://openalex.org/W2007185453","https://openalex.org/W2008544782","https://openalex.org/W2009163734","https://openalex.org/W2017443683","https://openalex.org/W2020770216","https://openalex.org/W2021426245","https://openalex.org/W2028304696","https://openalex.org/W2029667275","https://openalex.org/W2030491651","https://openalex.org/W2030631780","https://openalex.org/W2031596649","https://openalex.org/W2035414622","https://openalex.org/W2037950861","https://openalex.org/W2042780000","https://openalex.org/W2044598920","https://openalex.org/W2047148667","https://openalex.org/W2048764296","https://openalex.org/W2060298073","https://openalex.org/W2065853716","https://openalex.org/W2067835081","https://openalex.org/W2069437810","https://openalex.org/W2071865325","https://openalex.org/W2072016770","https://openalex.org/W2074500248","https://openalex.org/W2080308960","https://openalex.org/W2082980948","https://openalex.org/W2083637493","https://openalex.org/W2083759302","https://openalex.org/W2092185230","https://openalex.org/W2092762214","https://openalex.org/W2093452758","https://openalex.org/W2095164057","https://openalex.org/W2100393265","https://openalex.org/W2101176370","https://openalex.org/W2106244265","https://openalex.org/W2109832047","https://openalex.org/W2110238320","https://openalex.org/W2112324990","https://openalex.org/W2124162221","https://openalex.org/W2129463597","https://openalex.org/W2130947879","https://openalex.org/W2137064221","https://openalex.org/W2138291177","https://openalex.org/W2144424601","https://openalex.org/W2146906769","https://openalex.org/W2147377616","https://openalex.org/W2152468499","https://openalex.org/W2154750914","https://openalex.org/W2156953890","https://openalex.org/W2157002193","https://openalex.org/W2164381959","https://openalex.org/W2164582479","https://openalex.org/W2169152679","https://openalex.org/W2170726428","https://openalex.org/W2180470224","https://openalex.org/W2283020313","https://openalex.org/W4302069788"],"related_works":["https://openalex.org/W864489222","https://openalex.org/W7220607193","https://openalex.org/W2009506548","https://openalex.org/W2762742551","https://openalex.org/W7054953494","https://openalex.org/W1579466424","https://openalex.org/W2169152679","https://openalex.org/W2893778795","https://openalex.org/W7120512849","https://openalex.org/W2767338041"],"abstract_inverted_index":{"Pfaffia":[0],"glomerata":[1,72,115,198],"(Spreng.)":[2],"Pedersen":[3],"(\u201cginseng":[4],"brasileiro\u201d)":[5],"\u00e9":[6,63,85,89],"uma":[7],"planta":[8],"medicinal":[9],"que":[10,65,222,236],"apresenta":[11],"um":[12,36,217,237],"amplo":[13],"espectro":[14],"de":[15,28,39,47,79,113,122,178,187,196,202,212,216,235,246],"usos":[16],"como":[17,32,44,88,103],"t\u00f4nico,":[18],"antiestresse":[19,249],"e":[20,34,77,152,154,159,163,180,185,210],"afrodis\u00edaco.":[21],"Esta":[22],"esp\u00e9cie":[23],"pertence":[24],"ao":[25],"complexo":[26],"grupo":[27,37],"plantas":[29,40],"medicinais":[30],"conhecidas":[31],"\u201cginseng\u201d":[33],"comp\u00f5e":[35],"espec\u00edfico":[38],"denominadas":[41],"adapt\u00f3genas,":[42],"definidas":[43],"produtos":[45],"capazes":[46,201],"aumentar":[48],"a":[49,56,106,176,183,193,204,232],"resist\u00eancia":[50],"n\u00e3o":[51,199],"espec\u00edfica":[52],"do":[53,149,168],"organismo":[54],"frente":[55],"diferentes":[57],"est\u00edmulos":[58],"estressores;":[59],"considerando-se":[60],"tal":[61],"defini\u00e7\u00e3o,":[62],"previs\u00edvel":[64],"os":[66],"compostos":[67,188],"fitoqu\u00edmicos":[68],"presentes":[69],"na":[70,81,214],"P.":[71,114,197],"sejam":[73],"\u00fateis":[74],"no":[75],"controle":[76],"preven\u00e7\u00e3o":[78],"doen\u00e7as":[80],"qual":[82],"o":[83,90,99,120,241],"estresse":[84],"fator":[86],"etiol\u00f3gico,":[87],"caso":[91],"da":[92,110,142,145,157,160,165],"Doen\u00e7a":[93],"Inflamat\u00f3ria":[94],"Intestinal":[95],"(DII).":[96],"Dessa":[97],"forma,":[98],"presente":[100],"trabalho":[101],"possui":[102],"objetivo":[104],"avaliar":[105],"atividade":[107],"anti-inflamat\u00f3ria":[108],"intestinal":[109,125,220],"fra\u00e7\u00e3o":[111,194],"butan\u00f3lica":[112,195],"(rica":[116],"em":[117,133],"saponinas),":[118],"sobre":[119],"modelo":[121],"doen\u00e7a":[123],"inflamat\u00f3ria":[124],"induzida":[126],"por":[127,244],"\u00e1cido":[128],"2,":[129],"4,":[130],"6-trinitrobenzenosulf\u00f4nico":[131],"(TNBS)":[132],"ratos.":[134],"Para":[135],"tal,":[136],"foram":[137,200],"estudados":[138],"par\u00e2metros":[139],"macrosc\u00f3picos":[140],"(escore":[141],"les\u00e3o,":[143,146],"extens\u00e3o":[144],"rela\u00e7\u00e3o":[147],"peso/comprimento":[148],"c\u00f3lon,":[150],"diarreia":[151],"ader\u00eancia)":[153],"bioqu\u00edmicos":[155],"(atividade":[156],"mieloperoxidase":[158],"fosfatase":[161],"alcalina":[162],"quantifica\u00e7\u00e3o":[164],"glutationa":[166],"total)":[167],"processo":[169],"inflamat\u00f3rio":[170,219],"intestinal.":[171],"An\u00e1lises":[172],"fitoqu\u00edmicas":[173],"mostraram":[174],"principalmente":[175],"presen\u00e7a":[177],"triterpenos":[179],"saponinas,":[181],"incluindo":[182],"ecdisterona,":[184],"ind\u00edcios":[186],"fen\u00f3licos.":[189],"Os":[190],"tratamentos":[191],"com":[192],"impedir":[203],"forma\u00e7\u00e3o":[205],"les\u00f5es":[206],"induzidas":[207],"pelo":[208,226],"TNBS":[209],"nem":[211],"auxiliar":[213],"resolu\u00e7\u00e3o":[215],"quadro":[218],"pr\u00e9-existente,":[221],"tamb\u00e9m":[223],"foi":[224,250],"causado":[225],"TNBS.":[227],"Com":[228],"base":[229],"nestes":[230],"dados,":[231],"hip\u00f3tese":[233],"inicial":[234],"produto":[238],"adapt\u00f3geno":[239],"modularia":[240],"sistema":[242],"imune":[243],"meio":[245],"sua":[247],"a\u00e7\u00e3o":[248],"rejeitada":[251],"nas":[252],"condi\u00e7\u00f5es":[253],"experimentais":[254],"utilizadas":[255]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}