{"id":"https://openalex.org/W7903920","doi":"https://doi.org/10.1007/978-1-4899-0750-9_4","title":"Carbonic Anhydrase Kinetics and Molecular Function","display_name":"Carbonic Anhydrase Kinetics and Molecular Function","publication_year":1991,"publication_date":"1991-01-01","ids":{"openalex":"https://openalex.org/W7903920","doi":"https://doi.org/10.1007/978-1-4899-0750-9_4","mag":"7903920"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-4899-0750-9_4","doi":"https://doi.org/10.1007/978-1-4899-0750-9_4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4899-0750-9_4","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Carbonic Anhydrases","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4234949855","display_name":"The Carbonic Anhydrases"},"type":"book-chapter","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111589331","display_name":"Raja G. Khalifah","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210154663","display_name":"Kansas City VA Medical Center","ror":"https://ror.org/050mdr969","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210154663","https://openalex.org/I4210165236"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Raja G. Khalifah","raw_affiliation_strings":["Biochemistry Department, Kansas University Medical School, and Research Service, Veterans Administration Medical Center, Kansas City, Missouri, 64128, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biochemistry Department, Kansas University Medical School, and Research Service, Veterans Administration Medical Center, Kansas City, Missouri, 64128, USA","institution_ids":["https://openalex.org/I4210154663"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111475805","display_name":"David N. Silverman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800717037","display_name":"University of Florida Health","ror":"https://ror.org/04tk2gy88","country_code":"US","type":"education","lineage":["https://openalex.org/I2800717037","https://openalex.org/I33213144"]},{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David N. Silverman","raw_affiliation_strings":["Department of Pharmacology, University of Florida College of Medicine, Gainesville, Florida, 32610, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, University of Florida College of Medicine, Gainesville, Florida, 32610, USA","institution_ids":["https://openalex.org/I2800717037","https://openalex.org/I33213144"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6835,"has_fulltext":false,"cited_by_count":31,"citation_normalized_percentile":{"value":0.70877394,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":null,"issue":null,"first_page":"49","last_page":"70"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12412","display_name":"Enzyme function and inhibition","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12412","display_name":"Enzyme function and inhibition","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12191","display_name":"Physical Organic Chemistry and Reaction Kinetics","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12827","display_name":"Biochemical and Molecular Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/carbonic-anhydrase","display_name":"carbonic anhydrase","score":1.0},{"id":"https://openalex.org/keywords/enzyme-kinetics","display_name":"enzyme kinetics","score":0.9430000185966492},{"id":"https://openalex.org/keywords/zinc-enzymes","display_name":"zinc metalloenzyme","score":0.8759999871253967},{"id":"https://openalex.org/keywords/enzyme-mechanism","display_name":"enzyme mechanism","score":0.6850000023841858},{"id":"https://openalex.org/keywords/ca-i","display_name":"CA I","score":0.7070000171661377},{"id":"https://openalex.org/keywords/ca-ii","display_name":"Ca II","score":1.0},{"id":"https://openalex.org/keywords/skeletal-muscle","display_name":"skeletal muscle","score":0.7429999709129333},{"id":"https://openalex.org/keywords/isoenzymes","display_name":"isozymes","score":0.7369999885559082}],"concepts":[{"id":"https://openalex.org/C2775914622","wikidata":"https://www.wikidata.org/wiki/Q284089","display_name":"Carbonic anhydrase","level":3,"score":0.8568094968795776},{"id":"https://openalex.org/C119795356","wikidata":"https://www.wikidata.org/wiki/Q407801","display_name":"Isozyme","level":3,"score":0.802751362323761},{"id":"https://openalex.org/C148898269","wikidata":"https://www.wikidata.org/wiki/Q1108792","display_name":"Kinetics","level":2,"score":0.6809917092323303},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.574608325958252},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5724655389785767},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.4969811737537384},{"id":"https://openalex.org/C2780416268","wikidata":"https://www.wikidata.org/wiki/Q18021049","display_name":"Carbonic anhydrase II","level":4,"score":0.47735050320625305},{"id":"https://openalex.org/C56856141","wikidata":"https://www.wikidata.org/wiki/Q883112","display_name":"Enzyme kinetics","level":4,"score":0.4556891620159149},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.4263782799243927},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2677421569824219},{"id":"https://openalex.org/C41183919","wikidata":"https://www.wikidata.org/wiki/Q423026","display_name":"Active site","level":3,"score":0.16838207840919495},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.12871822714805603},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-1-4899-0750-9_4","doi":"https://doi.org/10.1007/978-1-4899-0750-9_4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4899-0750-9_4","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Carbonic Anhydrases","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":105,"referenced_works":["https://openalex.org/W99068490","https://openalex.org/W188267455","https://openalex.org/W658839705","https://openalex.org/W1484418190","https://openalex.org/W1484765693","https://openalex.org/W1495326083","https://openalex.org/W1498408076","https://openalex.org/W1524910142","https://openalex.org/W1530537945","https://openalex.org/W1564924642","https://openalex.org/W1572651262","https://openalex.org/W1573899446","https://openalex.org/W1585542991","https://openalex.org/W1589380177","https://openalex.org/W1605257743","https://openalex.org/W1611707636","https://openalex.org/W1646610592","https://openalex.org/W1648076034","https://openalex.org/W1963889508","https://openalex.org/W1963970506","https://openalex.org/W1965648605","https://openalex.org/W1970794990","https://openalex.org/W1970864720","https://openalex.org/W1972548580","https://openalex.org/W1972736163","https://openalex.org/W1973164496","https://openalex.org/W1976489967","https://openalex.org/W1976584967","https://openalex.org/W1978578205","https://openalex.org/W1979819808","https://openalex.org/W1983219972","https://openalex.org/W1983563055","https://openalex.org/W1985562961","https://openalex.org/W1988295340","https://openalex.org/W1991845997","https://openalex.org/W1993038817","https://openalex.org/W1997830784","https://openalex.org/W2002398620","https://openalex.org/W2006057889","https://openalex.org/W2006391622","https://openalex.org/W2011300931","https://openalex.org/W2011598602","https://openalex.org/W2012132546","https://openalex.org/W2012506672","https://openalex.org/W2013259170","https://openalex.org/W2014549495","https://openalex.org/W2015369153","https://openalex.org/W2016065841","https://openalex.org/W2020524973","https://openalex.org/W2023518846","https://openalex.org/W2026081513","https://openalex.org/W2027322752","https://openalex.org/W2030788726","https://openalex.org/W2030855834","https://openalex.org/W2031846520","https://openalex.org/W2033144722","https://openalex.org/W2035179880","https://openalex.org/W2036005020","https://openalex.org/W2038203477","https://openalex.org/W2038373026","https://openalex.org/W2043288008","https://openalex.org/W2045570939","https://openalex.org/W2045975124","https://openalex.org/W2046883456","https://openalex.org/W2048016835","https://openalex.org/W2061010116","https://openalex.org/W2064223913","https://openalex.org/W2064422557","https://openalex.org/W2067132543","https://openalex.org/W2067564894","https://openalex.org/W2069339816","https://openalex.org/W2070967751","https://openalex.org/W2072665004","https://openalex.org/W2072693069","https://openalex.org/W2079312975","https://openalex.org/W2080666337","https://openalex.org/W2080785168","https://openalex.org/W2081652699","https://openalex.org/W2081844661","https://openalex.org/W2082954445","https://openalex.org/W2084774359","https://openalex.org/W2086272406","https://openalex.org/W2087062176","https://openalex.org/W2087227246","https://openalex.org/W2087903652","https://openalex.org/W2088451388","https://openalex.org/W2094991001","https://openalex.org/W2100594010","https://openalex.org/W2113127234","https://openalex.org/W2118262335","https://openalex.org/W2151412416","https://openalex.org/W2153023761","https://openalex.org/W2162703779","https://openalex.org/W2168935917","https://openalex.org/W2238928746","https://openalex.org/W2329265014","https://openalex.org/W2330333810","https://openalex.org/W2335362505","https://openalex.org/W2403242971","https://openalex.org/W2466762135","https://openalex.org/W2503757290","https://openalex.org/W3005034699","https://openalex.org/W4237190377","https://openalex.org/W4239075469","https://openalex.org/W4254743406"],"related_works":["https://openalex.org/W2269746293","https://openalex.org/W2219677798","https://openalex.org/W54934979","https://openalex.org/W128113274","https://openalex.org/W99068490","https://openalex.org/W1576380884","https://openalex.org/W1957404494","https://openalex.org/W2035046825","https://openalex.org/W102152435","https://openalex.org/W2151117408"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2016-06-24T00:00:00"}