{"id":"https://openalex.org/W78748194","doi":"https://doi.org/10.1023/a:1013017821166","title":"Evaluation of Systemically Administered Radiolabeled Epidermal growth Factor as a Brain Tumor Targeting Agent","display_name":"Evaluation of Systemically Administered Radiolabeled Epidermal growth Factor as a Brain Tumor Targeting Agent","publication_year":2001,"publication_date":"2001-10-01","ids":{"openalex":"https://openalex.org/W78748194","doi":"https://doi.org/10.1023/a:1013017821166","mag":"78748194","pmid":"https://pubmed.ncbi.nlm.nih.gov/11804279"},"language":"en","primary_location":{"id":"doi:10.1023/a:1013017821166","doi":"https://doi.org/10.1023/a:1013017821166","is_oa":false,"landing_page_url":"https://doi.org/10.1023/a:1013017821166","pdf_url":null,"source":{"id":"https://openalex.org/S175922936","display_name":"Journal of Neuro-Oncology","issn_l":"0167-594X","issn":["0167-594X","1573-7373"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuro-Oncology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102851213","display_name":"Weilian Yang","orcid":"https://orcid.org/0000-0002-7776-7539","observed_orcids":["https://orcid.org/0000-0002-7776-7539"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Weilian Yang","raw_affiliation_strings":["Department of Pathology, The Ohio State University, Columbus 43210, USA","Department of Pathology, The Ohio State University Columbus, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, The Ohio State University, Columbus 43210, USA","institution_ids":["https://openalex.org/I52357470"]},{"raw_affiliation_string":"Department of Pathology, The Ohio State University Columbus, USA","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012238012","display_name":"Rolf F. Barth","orcid":"https://orcid.org/0000-0002-2616-472X","observed_orcids":["https://orcid.org/0000-0002-2616-472X"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rolf F. Barth","raw_affiliation_strings":["Department of Pathology, The Ohio State University, Columbus, OH, USA","Department of Pathology, The Ohio State University Columbus, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, The Ohio State University, Columbus, OH, USA","institution_ids":["https://openalex.org/I52357470"]},{"raw_affiliation_string":"Department of Pathology, The Ohio State University Columbus, USA","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109458426","display_name":"Ren\u00e9e L\u00e9veill\u00e9","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Renee Leveille","raw_affiliation_strings":["Department of Veterinary Clinical Sciences, The Ohio State University, Columbus, OH, USA","Department of Veterinary Clinical Sciences; The Ohio State University; Columbus USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Clinical Sciences, The Ohio State University, Columbus, OH, USA","institution_ids":["https://openalex.org/I52357470"]},{"raw_affiliation_string":"Department of Veterinary Clinical Sciences; The Ohio State University; Columbus USA","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111168022","display_name":"Dianne M. Adams","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dianne M. Adams","raw_affiliation_strings":["Department of Pathology, The Ohio State University, Columbus, OH, USA","Department of Pathology, The Ohio State University Columbus, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, The Ohio State University, Columbus, OH, USA","institution_ids":["https://openalex.org/I52357470"]},{"raw_affiliation_string":"Department of Pathology, The Ohio State University Columbus, USA","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036910737","display_name":"Michael J. Ciesielski","orcid":"https://orcid.org/0000-0002-3373-9421","observed_orcids":["https://orcid.org/0000-0002-3373-9421"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael Ciesielski","raw_affiliation_strings":["VDIC, Clackmas, OR, USA","VDIC, Clackmas, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"VDIC, Clackmas, OR, USA","institution_ids":[]},{"raw_affiliation_string":"VDIC, Clackmas, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053202206","display_name":"Robert Alan Fenstermaker","orcid":"https://orcid.org/0000-0003-0309-8130","observed_orcids":["https://orcid.org/0000-0003-0309-8130"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robert A. Fenstermaker","raw_affiliation_strings":["VDIC, Clackmas, OR, USA","VDIC, Clackmas, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"VDIC, Clackmas, OR, USA","institution_ids":[]},{"raw_affiliation_string":"VDIC, Clackmas, USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041336753","display_name":"Jacek Capala","orcid":"https://orcid.org/0000-0001-7631-0310","observed_orcids":["https://orcid.org/0000-0001-7631-0310"]},"institutions":[{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Jacek Capala","raw_affiliation_strings":["Department of Radiation Sciences, Uppsala University, Uppsala, Sweden","Dept. of Radiation Sciences, Uppsala Univ., Uppsala (Sweden)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Sciences, Uppsala University, Uppsala, Sweden","institution_ids":["https://openalex.org/I123387679"]},{"raw_affiliation_string":"Dept. of Radiation Sciences, Uppsala Univ., Uppsala (Sweden)","institution_ids":["https://openalex.org/I123387679"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4590,"currency":"USD","value_usd":4590},"apc_paid":null,"fwci":2.3592,"has_fulltext":false,"cited_by_count":22,"citation_normalized_percentile":{"value":0.86573514,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"55","issue":"1","first_page":"19","last_page":"28"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.0034000000450760126,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/epidermal-growth-factor-receptor","display_name":"epidermal growth factor receptor","score":0.8519999980926514},{"id":"https://openalex.org/keywords/glioma","display_name":"glioma","score":0.6729999780654907},{"id":"https://openalex.org/keywords/brain-tumor-imaging","display_name":"brain tumor imaging","score":0.703000009059906},{"id":"https://openalex.org/keywords/intracarotid-administration","display_name":"intracarotid administration","score":0.8460000157356262},{"id":"https://openalex.org/keywords/blood-brain-barrier-disruption","display_name":"blood-brain barrier disruption","score":0.9279999732971191},{"id":"https://openalex.org/keywords/mannitol","display_name":"mannitol","score":0.9359999895095825},{"id":"https://openalex.org/keywords/tumor-targeting-agents","display_name":"tumor targeting agents","score":0.6179999709129333},{"id":"https://openalex.org/keywords/radioligand-biodistribution","display_name":"radioligand biodistribution","score":0.7250000238418579},{"id":"https://openalex.org/keywords/radionuclide-imaging","display_name":"scintigraphy","score":0.8230000138282776}],"concepts":[{"id":"https://openalex.org/C67847695","wikidata":"https://www.wikidata.org/wiki/Q626478","display_name":"Radioligand","level":3,"score":0.622584342956543},{"id":"https://openalex.org/C2776362946","wikidata":"https://www.wikidata.org/wiki/Q424374","display_name":"Epidermal growth factor","level":3,"score":0.5676859617233276},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.5060312151908875},{"id":"https://openalex.org/C2778445172","wikidata":"https://www.wikidata.org/wiki/Q407646","display_name":"Mannitol","level":2,"score":0.5042620897293091},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.43767327070236206},{"id":"https://openalex.org/C2779902710","wikidata":"https://www.wikidata.org/wiki/Q1130465","display_name":"Scintigraphy","level":2,"score":0.41170552372932434},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.38407596945762634},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.361420214176178},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3418229818344116},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.32698482275009155},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07287269830703735}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004815","descriptor_name":"Epidermal Growth Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004815","descriptor_name":"Epidermal Growth Factor","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":true},{"descriptor_ui":"D005910","descriptor_name":"Glioma","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D005910","descriptor_name":"Glioma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007275","descriptor_name":"Injections, Intravenous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011877","descriptor_name":"Radionuclide Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011916","descriptor_name":"Rats, Inbred F344","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014018","descriptor_name":"Tissue Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015552","descriptor_name":"Injections, Intralesional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015609","descriptor_name":"Organotechnetium Compounds","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066246","descriptor_name":"ErbB Receptors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1023/a:1013017821166","doi":"https://doi.org/10.1023/a:1013017821166","is_oa":false,"landing_page_url":"https://doi.org/10.1023/a:1013017821166","pdf_url":null,"source":{"id":"https://openalex.org/S175922936","display_name":"Journal of Neuro-Oncology","issn_l":"0167-594X","issn":["0167-594X","1573-7373"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuro-Oncology","raw_type":"journal-article"},{"id":"pmid:11804279","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11804279","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neuro-oncology","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.6499999761581421,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306084","display_name":"U.S. Department of Energy","ror":"https://ror.org/01bj3aw27"},{"id":"https://openalex.org/F4320333966","display_name":"American Regent","ror":"https://ror.org/003f1dg75"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":44,"referenced_works":["https://openalex.org/W69687228","https://openalex.org/W1506943393","https://openalex.org/W1617881058","https://openalex.org/W1898103072","https://openalex.org/W1965282431","https://openalex.org/W1967726190","https://openalex.org/W1968821699","https://openalex.org/W1977878414","https://openalex.org/W1996099807","https://openalex.org/W1998732222","https://openalex.org/W1999358182","https://openalex.org/W2007719782","https://openalex.org/W2009021377","https://openalex.org/W2033786262","https://openalex.org/W2046734012","https://openalex.org/W2053949693","https://openalex.org/W2054232940","https://openalex.org/W2057458801","https://openalex.org/W2059435192","https://openalex.org/W2063922604","https://openalex.org/W2063978979","https://openalex.org/W2064551456","https://openalex.org/W2067157437","https://openalex.org/W2071386399","https://openalex.org/W2071770777","https://openalex.org/W2076674267","https://openalex.org/W2091881303","https://openalex.org/W2097670451","https://openalex.org/W2099708088","https://openalex.org/W2107388094","https://openalex.org/W2111885759","https://openalex.org/W2117553516","https://openalex.org/W2121058401","https://openalex.org/W2132851377","https://openalex.org/W2170160933","https://openalex.org/W2197753603","https://openalex.org/W2272177119","https://openalex.org/W2325631775","https://openalex.org/W2346718807","https://openalex.org/W2413131264","https://openalex.org/W2414852757","https://openalex.org/W2415012426","https://openalex.org/W2468182085","https://openalex.org/W4236530705"],"related_works":["https://openalex.org/W2067157437","https://openalex.org/W2489130515","https://openalex.org/W2377792081","https://openalex.org/W1617881058","https://openalex.org/W2064551456","https://openalex.org/W2416899275","https://openalex.org/W2080079411","https://openalex.org/W2043710627","https://openalex.org/W2010231226","https://openalex.org/W2041473771"],"abstract_inverted_index":null,"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}