{"id":"https://openalex.org/W7846284","doi":"https://doi.org/10.1002/j.1460-2075.1996.tb00992.x","title":"Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation.","display_name":"Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation.","publication_year":1996,"publication_date":"1996-11-01","ids":{"openalex":"https://openalex.org/W7846284","doi":"https://doi.org/10.1002/j.1460-2075.1996.tb00992.x","mag":"7846284","pmid":"https://pubmed.ncbi.nlm.nih.gov/8947026","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/452425"},"language":"en","primary_location":{"id":"doi:10.1002/j.1460-2075.1996.tb00992.x","doi":"https://doi.org/10.1002/j.1460-2075.1996.tb00992.x","is_oa":false,"landing_page_url":"https://doi.org/10.1002/j.1460-2075.1996.tb00992.x","pdf_url":null,"source":{"id":"https://openalex.org/S127916151","display_name":"The EMBO Journal","issn_l":"0261-4189","issn":["0261-4189","1460-2075"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The EMBO Journal","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W7846284"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/452425","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009018397","display_name":"Donata Orioli","orcid":"https://orcid.org/0000-0002-3830-3408","observed_orcids":["https://orcid.org/0000-0002-3830-3408"]},"institutions":[{"id":"https://openalex.org/I4210138560","display_name":"European Molecular Biology Laboratory","ror":"https://ror.org/03mstc592","country_code":"DE","type":"government","lineage":["https://openalex.org/I4210138560"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"D. Orioli","raw_affiliation_strings":["European Molecular Biology Laboratory, Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"European Molecular Biology Laboratory, Heidelberg, Germany","institution_ids":["https://openalex.org/I4210138560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036697210","display_name":"Mark J. Henkemeyer","orcid":"https://orcid.org/0000-0002-7525-1061","observed_orcids":["https://orcid.org/0000-0002-7525-1061"]},"institutions":[{"id":"https://openalex.org/I4210138560","display_name":"European Molecular Biology Laboratory","ror":"https://ror.org/03mstc592","country_code":"DE","type":"government","lineage":["https://openalex.org/I4210138560"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"M. Henkemeyer","raw_affiliation_strings":["European Molecular Biology Laboratory, Heidelberg, Germany","Developmental Biology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"European Molecular Biology Laboratory, Heidelberg, Germany","institution_ids":["https://openalex.org/I4210138560"]},{"raw_affiliation_string":"Developmental Biology","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065903201","display_name":"Greg Lemke","orcid":"https://orcid.org/0000-0001-5805-9855","observed_orcids":["https://orcid.org/0000-0001-5805-9855"]},"institutions":[{"id":"https://openalex.org/I1307098950","display_name":"Salk Institute for Biological Studies","ror":"https://ror.org/03xez1567","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1307098950"]},{"id":"https://openalex.org/I4210138560","display_name":"European Molecular Biology Laboratory","ror":"https://ror.org/03mstc592","country_code":"DE","type":"government","lineage":["https://openalex.org/I4210138560"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"G. Lemke","raw_affiliation_strings":["European Molecular Biology Laboratory, Heidelberg, Germany","Salk Institute for Biological Studies"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"European Molecular Biology Laboratory, Heidelberg, Germany","institution_ids":["https://openalex.org/I4210138560"]},{"raw_affiliation_string":"Salk Institute for Biological Studies","institution_ids":["https://openalex.org/I1307098950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063529902","display_name":"R\u00fcdiger Klein","orcid":"https://orcid.org/0000-0002-3109-0163","observed_orcids":["https://orcid.org/0000-0002-3109-0163"]},"institutions":[{"id":"https://openalex.org/I4210138560","display_name":"European Molecular Biology Laboratory","ror":"https://ror.org/03mstc592","country_code":"DE","type":"government","lineage":["https://openalex.org/I4210138560"]},{"id":"https://openalex.org/I4210153543","display_name":"European Molecular Biology Laboratory","ror":"https://ror.org/050589e39","country_code":"DE","type":"government","lineage":["https://openalex.org/I4210138560","https://openalex.org/I4210153543"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"R. Klein","raw_affiliation_strings":["European Molecular Biology Laboratory, Heidelberg, Germany","European Molecular Biology Laboratory"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"European Molecular Biology Laboratory, Heidelberg, Germany","institution_ids":["https://openalex.org/I4210138560"]},{"raw_affiliation_string":"European Molecular Biology Laboratory","institution_ids":["https://openalex.org/I4210138560","https://openalex.org/I4210153543"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109102479","display_name":"Tony J. Pawson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I4210138560","display_name":"European Molecular Biology Laboratory","ror":"https://ror.org/03mstc592","country_code":"DE","type":"government","lineage":["https://openalex.org/I4210138560"]}],"countries":["CA","DE"],"is_corresponding":false,"raw_author_name":"T. Pawson","raw_affiliation_strings":["European Molecular Biology Laboratory, Heidelberg, Germany","University of Toronto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"European Molecular Biology Laboratory, Heidelberg, Germany","institution_ids":["https://openalex.org/I4210138560"]},{"raw_affiliation_string":"University of Toronto","institution_ids":["https://openalex.org/I185261750"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":7990,"currency":"USD","value_usd":7990},"apc_paid":null,"fwci":10.0075,"has_fulltext":false,"cited_by_count":330,"citation_normalized_percentile":{"value":0.99093141,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":100},"biblio":{"volume":"15","issue":"22","first_page":"6035","last_page":"6049"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12061","display_name":"Axon Guidance and Neuronal Signaling","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12061","display_name":"Axon Guidance and Neuronal Signaling","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/commissural-axon-guidance","display_name":"commissural axon guidance","score":0.8759999871253967},{"id":"https://openalex.org/keywords/anterior-commissure","display_name":"anterior commissure","score":0.8519999980926514},{"id":"https://openalex.org/keywords/corpus-callosum","display_name":"corpus callosum","score":0.9580000042915344},{"id":"https://openalex.org/keywords/axon-fasciculation","display_name":"axon fasciculation","score":0.8360000252723694},{"id":"https://openalex.org/keywords/cleft-palate","display_name":"cleft palate","score":0.7570000290870667},{"id":"https://openalex.org/keywords/receptor-redundancy","display_name":"receptor redundancy","score":0.5490000247955322},{"id":"https://openalex.org/keywords/brain-development","display_name":"brain development","score":0.5630000233650208},{"id":"https://openalex.org/keywords/facial-growth","display_name":"facial growth","score":0.8029999732971191}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9238262176513672},{"id":"https://openalex.org/C100207259","wikidata":"https://www.wikidata.org/wiki/Q489628","display_name":"Commissure","level":2,"score":0.7463535070419312},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.5385933518409729},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5072262287139893},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.41852515935897827},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.32125699520111084},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.18844953179359436}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001369","descriptor_name":"Axons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002490","descriptor_name":"Central Nervous System","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D002490","descriptor_name":"Central Nervous System","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002972","descriptor_name":"Cleft Palate","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003337","descriptor_name":"Corpus Callosum","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D003337","descriptor_name":"Corpus Callosum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005326","descriptor_name":"Fetal Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006579","descriptor_name":"Heterozygote","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006651","descriptor_name":"Histocytochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006720","descriptor_name":"Homozygote","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009419","descriptor_name":"Nerve Tissue Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010159","descriptor_name":"Palate","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011956","descriptor_name":"Receptors, Cell Surface","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011956","descriptor_name":"Receptors, Cell Surface","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013194","descriptor_name":"Staining and Labeling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013234","descriptor_name":"Stem Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018390","descriptor_name":"Gene Targeting","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D018507","descriptor_name":"Gene Expression Regulation, Developmental","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D020794","descriptor_name":"Receptor Protein-Tyrosine Kinases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D036122","descriptor_name":"Receptor, EphA4","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D036183","descriptor_name":"Receptor, EphB2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D036383","descriptor_name":"Ephrin-A2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1002/j.1460-2075.1996.tb00992.x","doi":"https://doi.org/10.1002/j.1460-2075.1996.tb00992.x","is_oa":false,"landing_page_url":"https://doi.org/10.1002/j.1460-2075.1996.tb00992.x","pdf_url":null,"source":{"id":"https://openalex.org/S127916151","display_name":"The EMBO Journal","issn_l":"0261-4189","issn":["0261-4189","1460-2075"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The EMBO Journal","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:201241","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/452425","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:8947026","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8947026","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The EMBO journal","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:452425","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC452425/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EMBO J","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:201241","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/452425","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":59,"referenced_works":["https://openalex.org/W55585949","https://openalex.org/W67864123","https://openalex.org/W194084071","https://openalex.org/W198779817","https://openalex.org/W1604510112","https://openalex.org/W1832821166","https://openalex.org/W1895213472","https://openalex.org/W1965730322","https://openalex.org/W1966697925","https://openalex.org/W1967740144","https://openalex.org/W1974130613","https://openalex.org/W1977219612","https://openalex.org/W1977455576","https://openalex.org/W1980094138","https://openalex.org/W1981298313","https://openalex.org/W1984755886","https://openalex.org/W1987237521","https://openalex.org/W1991558418","https://openalex.org/W1993193182","https://openalex.org/W1993517206","https://openalex.org/W1998645764","https://openalex.org/W2006753901","https://openalex.org/W2012116939","https://openalex.org/W2013293997","https://openalex.org/W2016010426","https://openalex.org/W2017519742","https://openalex.org/W2023023843","https://openalex.org/W2023381747","https://openalex.org/W2026897880","https://openalex.org/W2028408655","https://openalex.org/W2029240437","https://openalex.org/W2029441863","https://openalex.org/W2034064964","https://openalex.org/W2038894508","https://openalex.org/W2046080148","https://openalex.org/W2051453643","https://openalex.org/W2059324182","https://openalex.org/W2069019173","https://openalex.org/W2074242619","https://openalex.org/W2074345277","https://openalex.org/W2082581761","https://openalex.org/W2084329240","https://openalex.org/W2088023367","https://openalex.org/W2088609693","https://openalex.org/W2088904620","https://openalex.org/W2090116482","https://openalex.org/W2092396168","https://openalex.org/W2134334134","https://openalex.org/W2141568746","https://openalex.org/W2150561524","https://openalex.org/W2163547089","https://openalex.org/W2337949001","https://openalex.org/W2394876538","https://openalex.org/W2410436091","https://openalex.org/W2410604860","https://openalex.org/W2412344525","https://openalex.org/W2413470816","https://openalex.org/W2417871234","https://openalex.org/W4212811418"],"related_works":["https://openalex.org/W4240147589","https://openalex.org/W2074345277","https://openalex.org/W2110172543","https://openalex.org/W2102505480","https://openalex.org/W2413470816","https://openalex.org/W2143730384","https://openalex.org/W2123143418","https://openalex.org/W4224439016","https://openalex.org/W2001116008","https://openalex.org/W2013369476"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":16}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2016-06-24T00:00:00"}