{"id":"https://openalex.org/W780441360","doi":null,"title":"Perfusion Bioreactor Module","display_name":"Perfusion Bioreactor Module","publication_year":1990,"publication_date":"1990-07-01","ids":{"openalex":"https://openalex.org/W780441360","mag":"780441360"},"language":"en","primary_location":{"id":"mag:780441360","doi":null,"is_oa":false,"landing_page_url":"https://ntrs.nasa.gov/search.jsp?R=19900000377","pdf_url":null,"source":{"id":"https://openalex.org/S4306520501","display_name":"NASA Tech Briefs","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"NASA Tech Briefs","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051270501","display_name":"Dennis R. Morrison","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Dennis R. Morrison","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5051270501"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0681431,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"14","issue":"7","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10864","display_name":"Fluid Dynamics and Mixing","score":0.5814999938011169,"subfield":{"id":"https://openalex.org/subfields/1507","display_name":"Fluid Flow and Transfer Processes"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10864","display_name":"Fluid Dynamics and Mixing","score":0.5814999938011169,"subfield":{"id":"https://openalex.org/subfields/1507","display_name":"Fluid Flow and Transfer Processes"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11663","display_name":"Viral Infectious Diseases and Gene Expression in Insects","score":0.1808999925851822,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12005","display_name":"Spaceflight effects on biology","score":0.13850000500679016,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/perfusion-bioreactor","display_name":"perfusion bioreactor","score":0.9980000257492065},{"id":"https://openalex.org/keywords/microgravity","display_name":"microgravity","score":0.9169999957084656},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.7540000081062317},{"id":"https://openalex.org/keywords/cell-culture-maintenance","display_name":"cell culture maintenance","score":0.5260000228881836},{"id":"https://openalex.org/keywords/cell-secretion","display_name":"cell secretion","score":0.5120000243186951},{"id":"https://openalex.org/keywords/human-cells","display_name":"human cells","score":0.4560000002384186}],"concepts":[{"id":"https://openalex.org/C168170006","wikidata":"https://www.wikidata.org/wiki/Q864699","display_name":"Bioreactor","level":2,"score":0.8185766935348511},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5627127885818481},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.5096151828765869},{"id":"https://openalex.org/C146957229","wikidata":"https://www.wikidata.org/wiki/Q1266915","display_name":"Perfusion","level":2,"score":0.48148977756500244},{"id":"https://openalex.org/C75235859","wikidata":"https://www.wikidata.org/wiki/Q582659","display_name":"Exponential growth","level":2,"score":0.4783850908279419},{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.47648924589157104},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.4638493061065674},{"id":"https://openalex.org/C49039625","wikidata":"https://www.wikidata.org/wiki/Q84230","display_name":"Secretion","level":2,"score":0.4348011016845703},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.3930480480194092},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3726499080657959},{"id":"https://openalex.org/C21880701","wikidata":"https://www.wikidata.org/wiki/Q2144042","display_name":"Process engineering","level":1,"score":0.3713321089744568},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.35780656337738037},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3436740040779114},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3242514729499817},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.2937276363372803},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.19170141220092773},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.16444778442382812},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.07858210802078247},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.07785612344741821},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.06996974349021912},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:780441360","doi":null,"is_oa":false,"landing_page_url":"https://ntrs.nasa.gov/search.jsp?R=19900000377","pdf_url":null,"source":{"id":"https://openalex.org/S4306520501","display_name":"NASA Tech Briefs","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"NASA Tech Briefs","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2067092806","https://openalex.org/W2369543865","https://openalex.org/W1532909280","https://openalex.org/W1504780966","https://openalex.org/W2370099174","https://openalex.org/W2503347798","https://openalex.org/W4307572899","https://openalex.org/W831217753","https://openalex.org/W2127676197","https://openalex.org/W2438101936"],"abstract_inverted_index":{"Perfusion":[0],"bioreactor":[1],"module,":[2],"self-contained,":[3],"closed-loop":[4],"cell-culture":[5],"system":[6],"that":[7],"operates":[8],"in":[9,30,49,58],"microgravity":[10],"or":[11,17,24,34,66],"on":[12],"Earth.":[13],"Equipment":[14],"supports":[15],"growth":[16,51],"long-term":[18],"maintenance":[19],"of":[20,22,45,47,70,74,76],"cultures":[21],"human":[23],"other":[25],"fragile":[26],"cells":[27,48,57,77],"for":[28],"experiments":[29],"basic":[31],"cell":[32],"biology":[33],"process":[35],"technology.":[36],"Designed":[37],"to":[38,54,64],"support":[39],"proliferation":[40],"(initially":[41],"at":[42],"exponential":[43],"rates":[44],"growth)":[46],"complex":[50],"medium":[52,60],"and":[53],"maintain":[55],"confluent":[56],"defined":[59],"under":[61],"conditions":[62],"optimized":[63],"permit":[65],"encourage":[67],"selected":[68],"functions":[69],"cells,":[71],"including":[72],"secretion":[73],"products":[75],"into":[78],"medium.":[79]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}