{"id":"https://openalex.org/W77865875","doi":null,"title":"Acute Oral Toxicity Evaluation of 2,6-Dibutyl-4-Nitrophenol in Male Sprague-Dawley Rats","display_name":"Acute Oral Toxicity Evaluation of 2,6-Dibutyl-4-Nitrophenol in Male Sprague-Dawley Rats","publication_year":1999,"publication_date":"1999-06-01","ids":{"openalex":"https://openalex.org/W77865875","mag":"77865875"},"language":"en","primary_location":{"id":"pmh:ADA380383","doi":null,"is_oa":false,"landing_page_url":"http://oai.dtic.mil/oai/oai?&verb=getRecord&metadataPrefix=html&identifier=ADA380383","pdf_url":null,"source":{"id":"https://openalex.org/S4406923043","display_name":"Defense Technical Information Center (DTIC)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"DTIC AND NTIS","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002844014","display_name":"Kathleen L. MacMahon","orcid":"https://orcid.org/0000-0003-0257-3630","observed_orcids":["https://orcid.org/0000-0003-0257-3630"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"MacMahon, K. L.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044911567","display_name":"Winfield H. Baker","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Baker, W. H.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053120834","display_name":"W. Alexander","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alexander, W. K.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041132110","display_name":"K. Still","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Still, K. R.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":null,"display_name":"Briggs, G. B.","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Briggs, G. B.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.00569007,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.27250000834465027,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.27250000834465027,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10122","display_name":"Toxic Organic Pollutants Impact","score":0.15520000457763672,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14072","display_name":"Immunotoxicology and immune responses","score":0.14970000088214874,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acute-oral-toxicity","display_name":"acute oral toxicity","score":0.9459999799728394},{"id":"https://openalex.org/keywords/ld50","display_name":"LD50","score":0.6990000009536743},{"id":"https://openalex.org/keywords/no-observable-effect-level","display_name":"no-observable-effect level","score":0.6520000100135803},{"id":"https://openalex.org/keywords/2-6-di-t-butylphenol","display_name":"2,6-di-t-butylphenol","score":0.8399999737739563},{"id":"https://openalex.org/keywords/hyperthermia","display_name":"hyperthermia","score":0.7710000276565552},{"id":"https://openalex.org/keywords/subacute-toxicity","display_name":"subacute toxicity","score":0.46799999475479126}],"concepts":[{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.7262705564498901},{"id":"https://openalex.org/C2778206080","wikidata":"https://www.wikidata.org/wiki/Q856775","display_name":"Corn oil","level":2,"score":0.7148638963699341},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5975401997566223},{"id":"https://openalex.org/C116263406","wikidata":"https://www.wikidata.org/wiki/Q3299024","display_name":"Acute toxicity","level":3,"score":0.5892192125320435},{"id":"https://openalex.org/C2988377048","wikidata":"https://www.wikidata.org/wiki/Q93165","display_name":"Olive oil","level":2,"score":0.5574978590011597},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.430440753698349},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.4131268262863159},{"id":"https://openalex.org/C33070731","wikidata":"https://www.wikidata.org/wiki/Q7218","display_name":"Toxicology","level":1,"score":0.3303864002227783},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.27646806836128235},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.2547624111175537},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.20802444219589233},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.1238366961479187},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09880229830741882}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:ADA380383","doi":null,"is_oa":false,"landing_page_url":"http://oai.dtic.mil/oai/oai?&verb=getRecord&metadataPrefix=html&identifier=ADA380383","pdf_url":null,"source":{"id":"https://openalex.org/S4406923043","display_name":"Defense Technical Information Center (DTIC)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"DTIC AND NTIS","raw_type":"Text"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8371999859809875,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2044980590","https://openalex.org/W2066875529","https://openalex.org/W205110800","https://openalex.org/W247764933","https://openalex.org/W1553027596","https://openalex.org/W294581243","https://openalex.org/W2016187915","https://openalex.org/W1531245206","https://openalex.org/W2012307222","https://openalex.org/W63108408"],"abstract_inverted_index":{"This":[0],"study":[1],"investigated":[2],"the":[3,24],"acute":[4],"oral":[5],"toxicity":[6],"of":[7,89],"2,6-di-t-butyl-4-nitrophenol":[8],"(DBNP)":[9],"in":[10,17,61,91,115],"male":[11],"Sprague-Dawley":[12,55],"rats.":[13],"DBNP":[14,37,60,90,103],"is":[15,29,94,104],"formed":[16],"U.S.":[18],"submarines":[19],"when":[20],"lube":[21],"oil":[22,93],"containing":[23],"antioxidant":[25],"additive":[26],"2,6-di-t-butylphenol":[27],"(DBP)":[28],"nitrated":[30],"after":[31],"passing":[32],"through":[33],"an":[34],"electrostatic":[35],"precipitator.":[36],"has":[38],"triggered":[39],"human":[40],"health":[41],"concerns":[42],"due":[43],"to":[44,47],"its":[45],"adherence":[46],"painted":[48],"surfaces":[49],"causing":[50],"a":[51],"noticeable":[52],"yellowing.":[53],"Male":[54],"rats":[56],"were":[57,69,113],"dosed":[58],"with":[59],"corn":[62,92],"oil.":[63],"Survivors":[64],"at":[65,71,75,79,84],"each":[66],"dose":[67],"level":[68],"5/5":[70],"62.5":[72,107],"mg/kg,":[73,77,81],"4/5":[74],"78":[76],"2/5":[78],"98":[80],"and":[82,110],"015":[83],"250":[85],"mg/kg.":[86,96,108],"The":[87,97],"LD50":[88],"93":[95],"No":[98],"Observable":[99],"Effect":[100],"Level":[101],"for":[102],"less":[105],"than":[106],"Hyperthermia":[109],"severe":[111],"rigor":[112],"found":[114],"treated":[116],"animals.":[117]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2025-10-10T00:00:00"}