{"id":"https://openalex.org/W77457534","doi":null,"title":"Alteracions vasculars pulmonars indu\u00efdes per l\u2019exposici\u00f3 a fum de tabac en un model animal de MPOC","display_name":"Alteracions vasculars pulmonars indu\u00efdes per l\u2019exposici\u00f3 a fum de tabac en un model animal de MPOC","publication_year":2011,"publication_date":"2011-03-18","ids":{"openalex":"https://openalex.org/W77457534","mag":"77457534"},"language":"ca","primary_location":{"id":"pmh:oai:diposit.ub.edu:2445/42332","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/2445/42332","pdf_url":null,"source":{"id":"https://openalex.org/S4306401653","display_name":"Dip\u00f2sit Digital de la Universitat de Barcelona (Universitat de Barcelona)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I71999127","host_organization_name":"Universitat de Barcelona","host_organization_lineage":["https://openalex.org/I71999127"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tesis Doctorals - Departament - Medicina","raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10803/31871","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051935316","display_name":"Elisabet Ferrer Andr\u00e9s","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Elisabet Ferrer Andr\u00e9s","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5051935316"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10728","display_name":"Pulmonary Hypertension Research and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10728","display_name":"Pulmonary Hypertension Research and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12199","display_name":"Vascular Anomalies and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-obstructive-pulmonary-disease","display_name":"chronic obstructive pulmonary disease","score":0.9929999709129333},{"id":"https://openalex.org/keywords/cigarette-smoke","display_name":"cigarette smoke","score":0.6240000128746033},{"id":"https://openalex.org/keywords/pulmonary-hypertension","display_name":"pulmonary hypertension","score":0.9160000085830688},{"id":"https://openalex.org/keywords/pulmonary-vascular-remodeling","display_name":"pulmonary vascular remodeling","score":0.7269999980926514},{"id":"https://openalex.org/keywords/endothelial-dysfunction","display_name":"endothelial dysfunction","score":0.8029999732971191},{"id":"https://openalex.org/keywords/hypoxia","display_name":"hypoxia","score":0.8059999942779541},{"id":"https://openalex.org/keywords/chronic-hypoxia","display_name":"chronic hypoxia","score":0.7279999852180481},{"id":"https://openalex.org/keywords/pulmonary-circulation","display_name":"pulmonary circulation","score":0.4729999899864197},{"id":"https://openalex.org/keywords/emphysema","display_name":"emphysema","score":0.7570000290870667},{"id":"https://openalex.org/keywords/animal-models","display_name":"animal models","score":0.5109999775886536},{"id":"https://openalex.org/keywords/rats","display_name":"rats","score":0.6320000290870667},{"id":"https://openalex.org/keywords/pulmonary-artery-pressure","display_name":"pulmonary artery pressure","score":0.47999998927116394},{"id":"https://openalex.org/keywords/smoking-cessation-interventions","display_name":"smoking cessation interventions","score":0.3400000035762787},{"id":"https://openalex.org/keywords/smoking-cessation-self-help","display_name":"smoking cessation self-help","score":0.38199999928474426},{"id":"https://openalex.org/keywords/smoking-cessation-pharmacotherapy","display_name":"smoking cessation pharmacotherapy","score":0.4449999928474426}],"concepts":[{"id":"https://openalex.org/C15708023","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Humanities","level":1,"score":0.7893686890602112},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.33871620893478394},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3208755850791931}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:oai:diposit.ub.edu:2445/42332","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/2445/42332","pdf_url":null,"source":{"id":"https://openalex.org/S4306401653","display_name":"Dip\u00f2sit Digital de la Universitat de Barcelona (Universitat de Barcelona)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I71999127","host_organization_name":"Universitat de Barcelona","host_organization_lineage":["https://openalex.org/I71999127"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tesis Doctorals - Departament - Medicina","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"pmh:oai:dnet:tdr_________::462b497d09a6f08eef94d6560b70d605","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10803/31871","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"TDX (Tesis Doctorals en Xarxa)","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"pmh:oai:www.tdx.cat:10803/31871","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10803/31871","pdf_url":"http://hdl.handle.net/10803/31871","source":{"id":"https://openalex.org/S4306401111","display_name":"Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210090028","host_organization_name":"Consorci de Serveis Universitaris de Catalunya","host_organization_lineage":["https://openalex.org/I4210090028"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"TDX (Tesis Doctorals en Xarxa)","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:77457534","doi":null,"is_oa":false,"landing_page_url":"http://diposit.ub.edu/dspace/bitstream/2445/42332/2/EFA_TESI.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S4306531624","display_name":"TDX (Tesis Doctorals en Xarxa)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"TDX (Tesis Doctorals en Xarxa)","raw_type":null}],"best_oa_location":{"id":"pmh:oai:www.tdx.cat:10803/31871","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10803/31871","pdf_url":"http://hdl.handle.net/10803/31871","source":{"id":"https://openalex.org/S4306401111","display_name":"Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210090028","host_organization_name":"Consorci de Serveis Universitaris de Catalunya","host_organization_lineage":["https://openalex.org/I4210090028"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"TDX (Tesis Doctorals en Xarxa)","raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[{"score":0.9907000064849854,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320309764","display_name":"Fundaci\u00f3n BBVA","ror":"https://ror.org/01jzs3b90"},{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320323113","display_name":"Banco Bilbao Vizcaya Argentaria","ror":"https://ror.org/0537dnd74"},{"id":"https://openalex.org/F4320324494","display_name":"Sociedad Espa\u00f1ola de Neumolog\u00eda y Cirug\u00eda Tor\u00e1cica","ror":"https://ror.org/028h6g607"},{"id":"https://openalex.org/F4320334923","display_name":"Instituto de Salud Carlos III","ror":"https://ror.org/00ca2c886"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W77457534.pdf","grobid_xml":"https://content.openalex.org/works/W77457534.grobid-xml"},"referenced_works_count":224,"referenced_works":["https://openalex.org/W14872226","https://openalex.org/W35343555","https://openalex.org/W89952529","https://openalex.org/W123409649","https://openalex.org/W145204650","https://openalex.org/W158756034","https://openalex.org/W1473568274","https://openalex.org/W1485310175","https://openalex.org/W1519918054","https://openalex.org/W1537128240","https://openalex.org/W1567245406","https://openalex.org/W1568547719","https://openalex.org/W1588925236","https://openalex.org/W1644644121","https://openalex.org/W1782873284","https://openalex.org/W1835557501","https://openalex.org/W1857179464","https://openalex.org/W1892949664","https://openalex.org/W1905314305","https://openalex.org/W1941094264","https://openalex.org/W1962501432","https://openalex.org/W1964000264","https://openalex.org/W1964519011","https://openalex.org/W1965199428","https://openalex.org/W1965314960","https://openalex.org/W1966368391","https://openalex.org/W1970911936","https://openalex.org/W1971095820","https://openalex.org/W1973124530","https://openalex.org/W1973176928","https://openalex.org/W1974528705","https://openalex.org/W1975852659","https://openalex.org/W1975878727","https://openalex.org/W1976232102","https://openalex.org/W1980191732","https://openalex.org/W1980761600","https://openalex.org/W1981316991","https://openalex.org/W1981421731","https://openalex.org/W1981695910","https://openalex.org/W1982153589","https://openalex.org/W1987920125","https://openalex.org/W1997356019","https://openalex.org/W2000439023","https://openalex.org/W2001306556","https://openalex.org/W2001426234","https://openalex.org/W2003879854","https://openalex.org/W2006712928","https://openalex.org/W2009630486","https://openalex.org/W2009878890","https://openalex.org/W2010245527","https://openalex.org/W2012009584","https://openalex.org/W2013489935","https://openalex.org/W2014585321","https://openalex.org/W2016927483","https://openalex.org/W2017082953","https://openalex.org/W2019329939","https://openalex.org/W2019405521","https://openalex.org/W2023712580","https://openalex.org/W2025165995","https://openalex.org/W2026540690","https://openalex.org/W2026939372","https://openalex.org/W2028522067","https://openalex.org/W2030666214","https://openalex.org/W2030845834","https://openalex.org/W2032599764","https://openalex.org/W2032994157","https://openalex.org/W2034178928","https://openalex.org/W2038045721","https://openalex.org/W2038161096","https://openalex.org/W2039068212","https://openalex.org/W2039172749","https://openalex.org/W2041075406","https://openalex.org/W2044067781","https://openalex.org/W2045229154","https://openalex.org/W2046069669","https://openalex.org/W2050052243","https://openalex.org/W2051205461","https://openalex.org/W2052174437","https://openalex.org/W2052688542","https://openalex.org/W2053205239","https://openalex.org/W2054767155","https://openalex.org/W2055727906","https://openalex.org/W2055962798","https://openalex.org/W2059378625","https://openalex.org/W2059694924","https://openalex.org/W2060849426","https://openalex.org/W2061024429","https://openalex.org/W2062538521","https://openalex.org/W2063433296","https://openalex.org/W2065827751","https://openalex.org/W2066083814","https://openalex.org/W2067740038","https://openalex.org/W2067920235","https://openalex.org/W2069718808","https://openalex.org/W2070807328","https://openalex.org/W2073882417","https://openalex.org/W2074248400","https://openalex.org/W2075297735","https://openalex.org/W2075502845","https://openalex.org/W2075919386","https://openalex.org/W2078852567","https://openalex.org/W2079293612","https://openalex.org/W2079648278","https://openalex.org/W2082476238","https://openalex.org/W2082737488","https://openalex.org/W2082795276","https://openalex.org/W2082828974","https://openalex.org/W2083628313","https://openalex.org/W2085467958","https://openalex.org/W2086006446","https://openalex.org/W2090134402","https://openalex.org/W2092587325","https://openalex.org/W2093382413","https://openalex.org/W2095538229","https://openalex.org/W2096399692","https://openalex.org/W2096692326","https://openalex.org/W2098142497","https://openalex.org/W2099548121","https://openalex.org/W2103916161","https://openalex.org/W2105166354","https://openalex.org/W2105461208","https://openalex.org/W2107023570","https://openalex.org/W2107277218","https://openalex.org/W2110040793","https://openalex.org/W2110378267","https://openalex.org/W2111190622","https://openalex.org/W2112492665","https://openalex.org/W2112861506","https://openalex.org/W2113236035","https://openalex.org/W2113311606","https://openalex.org/W2113966427","https://openalex.org/W2115980523","https://openalex.org/W2116784557","https://openalex.org/W2116936653","https://openalex.org/W2117417680","https://openalex.org/W2117574981","https://openalex.org/W2117733780","https://openalex.org/W2118987880","https://openalex.org/W2119097771","https://openalex.org/W2119630077","https://openalex.org/W2120787671","https://openalex.org/W2121822802","https://openalex.org/W2122037815","https://openalex.org/W2123113465","https://openalex.org/W2123848794","https://openalex.org/W2124006946","https://openalex.org/W2125576273","https://openalex.org/W2125605790","https://openalex.org/W2126475210","https://openalex.org/W2127951128","https://openalex.org/W2128055117","https://openalex.org/W2128108814","https://openalex.org/W2129032743","https://openalex.org/W2130100726","https://openalex.org/W2130449101","https://openalex.org/W2130514108","https://openalex.org/W2131290734","https://openalex.org/W2131450462","https://openalex.org/W2132591373","https://openalex.org/W2133666391","https://openalex.org/W2133986939","https://openalex.org/W2134062132","https://openalex.org/W2134074027","https://openalex.org/W2137187223","https://openalex.org/W2140377941","https://openalex.org/W2141061213","https://openalex.org/W2143410589","https://openalex.org/W2143927454","https://openalex.org/W2144473231","https://openalex.org/W2144477621","https://openalex.org/W2145237733","https://openalex.org/W2145245837","https://openalex.org/W2145621175","https://openalex.org/W2146033970","https://openalex.org/W2146234408","https://openalex.org/W2146572449","https://openalex.org/W2147064547","https://openalex.org/W2147854094","https://openalex.org/W2150235382","https://openalex.org/W2150747753","https://openalex.org/W2154239113","https://openalex.org/W2156692732","https://openalex.org/W2157668111","https://openalex.org/W2158026075","https://openalex.org/W2159536730","https://openalex.org/W2163559718","https://openalex.org/W2164732757","https://openalex.org/W2165946847","https://openalex.org/W2166413791","https://openalex.org/W2167377685","https://openalex.org/W2167716603","https://openalex.org/W2167762171","https://openalex.org/W2169235268","https://openalex.org/W2169934928","https://openalex.org/W2171216672","https://openalex.org/W2171669504","https://openalex.org/W2179714439","https://openalex.org/W2180221472","https://openalex.org/W2182954747","https://openalex.org/W2183644045","https://openalex.org/W2184088679","https://openalex.org/W2195395987","https://openalex.org/W2203362636","https://openalex.org/W2222294260","https://openalex.org/W2277818519","https://openalex.org/W2313098007","https://openalex.org/W2316732921","https://openalex.org/W2331798828","https://openalex.org/W2334924346","https://openalex.org/W2336686419","https://openalex.org/W2336807915","https://openalex.org/W2340993926","https://openalex.org/W2341304214","https://openalex.org/W2343934094","https://openalex.org/W2396549906","https://openalex.org/W2403310127","https://openalex.org/W2409302887","https://openalex.org/W2415032012","https://openalex.org/W2416411509","https://openalex.org/W2419319331","https://openalex.org/W2470154218","https://openalex.org/W2472329600","https://openalex.org/W2614800967","https://openalex.org/W2745117750"],"related_works":["https://openalex.org/W2967415431","https://openalex.org/W7120877386","https://openalex.org/W7009897756","https://openalex.org/W2317056888","https://openalex.org/W7161557214","https://openalex.org/W7120629210","https://openalex.org/W142525846","https://openalex.org/W4396501532","https://openalex.org/W3027169437","https://openalex.org/W7037477132"],"abstract_inverted_index":{"Existeixen":[0],"evid\u00e8ncies":[1],"de":[2,9,30,39,52,59,69,83,94,119,127,135,138,146,150,204,243,255,277,281,324,336,342,358,372,381,386,389,393,396,399,424,437,450,459,467,474,484,500,513,527,534,548,572,575,609,612,616,619,634],"que":[3,13,66,78,333,414,544,582,593,640],"els":[4,132,144,299,375,419,441,454,479,587,599,642],"canvis":[5],"en":[6,16,54,91,102,117,174,228,239,294,330,344,363,391,418,434,453,478,541,601,622,628,637],"la":[7,10,17,28,31,50,60,79,92,95,99,139,153,164,199,331,339,345,359,430,435,528,546,553,560,576,579,610,617],"funci\u00f3":[8,237,580],"circulaci\u00f3":[11,140,346],"pulmonar,":[12,555],"tenen":[14,23],"lloc":[15],"malaltia":[18,120],"pulmonar":[19,47,97,121,167,173,347,452,530],"obstructiva":[20],"cr\u00f2nica":[21,290],"(MPOC),":[22],"el":[24,44,67,72,106,170,175,224,274,322,334,494,508,525,556,567,623,629,638],"seu":[25],"origen":[26],"a":[27,49,98,130,148,180,191,198,234,286,288,305,354,370,422,457,482,511,595,632],"lesi\u00f3":[29,343],"c\u00e8l.lula":[32],"endotelial":[33,238,379],"i":[34,77,85,152,159,169,209,227,246,321,429,471,550,559,574,615,636],"estan":[35],"causats":[36],"pel":[37,532,592],"consum":[38],"tabac.":[40,485],"No":[41],"obstant":[42],"aix\u00f2,":[43,181],"desenvolupament":[45],"d'hipertensi\u00f3":[46],"s'associa":[48],"pres\u00e8ncia":[51,392,473,519,611],"hipox\u00e8mia":[53],"les":[55,136,229,364,501],"fases":[56],"m\u00e9s":[57,287],"greus":[58],"malaltia.":[61],"La":[62],"nostra":[63],"hip\u00f2tesi":[64,332],"\u00e9s":[65,71,338,515],"fum":[68,82,126,149,254,335,371,423,458,483,512,533,571,633],"tabac":[70,84,151,337,373,425,433,460,514,549,573,635],"factor":[73],"iniciador":[74],"del":[75,81,310,312,432,448,465,504,562,570,589],"proc\u00e9s":[76],"combinaci\u00f3":[80,547],"hip\u00f2xia":[86,154,289,551,577],"t\u00e9":[87,109],"un":[88,114,202,446,463,607],"paper":[89,568],"cr\u00edtic":[90],"patog\u00e8nesi":[93],"hipertensi\u00f3":[96],"MPOC.":[100],"Tenint":[101],"compte":[103],"aquests":[104],"antecedents,":[105],"present":[107],"projecte":[108],"dos":[110,643],"objectius.":[111],"1:":[112],"Desenvolupar":[113],"model":[115,177],"experimental":[116],"cobai":[118],"indu\u00efda":[122],"per":[123,201,491],"l'exposici\u00f3":[124,147],"al":[125,253],"tabac,":[128],"dirigit":[129],"avaluar":[131],"mecanismes":[133],"patog\u00e8nics":[134],"alteracions":[137],"pulmonar.":[141,327],"2:":[142],"Estudiar":[143],"efectes":[145],"cr\u00f2nica,":[155],"com":[156,462],"est\u00edmuls":[157],"separats":[158],"/":[160,194,258,262,315],"o":[161,489,497],"combinats,":[162],"sobre":[163,552,578],"pressi\u00f3":[165],"arterial":[166],"(PAP)":[168],"remodelat":[171,325,505,557,596],"vascular":[172,326,558,597],"mateix":[176,225,275],"animal.":[178],"Per":[179],"es":[182,415,539],"realitzaran":[183],"2":[184],"estudis:":[185],"Estudi":[186,248],"1)":[187],"35":[188],"cobais":[189,251,269,280],"exposats":[190,252,272,285,369,421,456,481],"7":[192],"cigarrets":[193,257],"dia,":[195,259],"5":[196,256,260],"dies":[197,261],"setmana":[200,263],"per\u00edode":[203,276],"3":[205],"(n":[206,212,218],"=":[207,213,219],"15)":[208],"6":[210],"mesos":[211],"20).":[214],"Un":[215],"grup":[216,283,624,630,639],"control":[217],"17)":[220],"s'exposar\u00e0":[221],"falsament":[222,271],"durant":[223,264,273,298],"temps":[226,509],"mateixes":[230],"condicions.":[231],"Les":[232,303],"variables":[233,304],"estudiar":[235,306],"s\u00f3n:":[236,307],"bany":[240],"d'\u00f2rgans,":[241],"morfometria":[242],"vasos":[244,468],"pulmonars":[245,366],"emfisema.":[247],"2)":[249],"32":[250,268],"12":[265],"setmanes.":[266],"Altres":[267],"seran":[270,284],"temps.":[278],"16":[279],"cada":[282],"(12%":[291],"O2)":[292],"24h/dia":[293],"una":[295,350],"c\u00e0mera":[296],"normob\u00e0rica":[297],"darrers":[300],"15":[301],"dies.":[302],"PAP,":[308],"relaci\u00f3":[309],"pes":[311,316],"ventricle":[313,317,563],"dret":[314],"esquerre":[318],"+":[319,470],"septe":[320],"grau":[323],"\\n\\n\\t\\t\\t\\t":[328],"Basant-nos":[329],"primera":[340],"causa":[341],"esperem":[348,413,444,517,583],"trobar":[349,518],"menor":[351],"resposta":[352,387],"vasodilatadora":[353,388],"agents":[355],"vasoactius":[356],"dependents":[357],"s\u00edntesi":[360],"d'\u00f2xid":[361,408],"n\u00edtric":[362,409],"art\u00e8ries":[365],"dels":[367],"animals":[368,420,455,480],"versus":[374],"controls.":[376],"Aquesta":[377],"disfunci\u00f3":[378],"hauria":[380],"ser":[382],"corroborada":[383],"amb":[384,404,472,626],"abs\u00e8ncia":[385],"l'art\u00e8ria":[390,451],"L-NAME":[394],"(inhibidor":[395],"l'enzim":[397],"convertidor":[398],"l'\u00f2xid":[400,438],"n\u00edtric).":[401],"En":[402,440],"concordan\u00e7a":[403],"aquest":[405,602],"resultat,":[406],"l'expressi\u00f3":[407],"mesurada":[410],"mitjan\u00e7ant":[411],"PCR":[412],"vegi":[416],"disminu\u00efda":[417],"explicant":[426],"aix\u00ed":[427,461],"l'alteraci\u00f3":[428],"implicaci\u00f3":[431],"via":[436],"n\u00edtric.":[439],"estudis":[442],"morfol\u00f2gics":[443],"demostrar":[445],"increment":[447,464],"gruix":[449],"nombre":[466],"\u03b1-actina":[469],"doble":[475],"l\u00e0mina":[476],"el\u00e0stica":[477],"El":[486,536],"marcatge":[487],"positiu":[488],"negatiu":[490],"desmina":[492],"determinar\u00e0":[493],"fenotip":[495],"diferenciat":[496],"primitiu":[498],"respectivament":[499],"c\u00e8l.lules":[502,620],"encarregades":[503],"vascular.\\n\\n\\t\\t\\t\\t":[506],"Si":[507,586],"d'exposici\u00f3":[510],"l'adequat":[516],"d'emfisema.":[520],"D'aquesta":[521],"manera":[522],"tamb\u00e9":[523],"determinarem":[524],"time-course":[526],"patologia":[529],"causada":[531],"tabac.\\n\\n\\t\\t\\t\\t":[535],"segon":[537,603],"estudi":[538,591,604],"centra":[540],"l'efecte":[542],"sin\u00e8rgic":[543],"presentaria":[545],"hemodin\u00e0mica":[554],"hipertr\u00f2fia":[561],"dret.":[564],"Tamb\u00e9":[565],"definiria":[566],"individual":[569],"endotelial,":[581],"sigui":[584],"deleteri.":[585],"resultats":[588],"primer":[590],"fa":[594],"s\u00f3n":[598],"esperats,":[600],"s\u2019hauria":[605],"d\u2019observar":[606],"augment":[608],"fibres":[613],"el\u00e0stiques":[614],"proliferaci\u00f3":[618],"musculars":[621],"tractat":[625],"hip\u00f2xia,":[627],"exposat":[631],"combina":[641],"factors.":[644]},"counts_by_year":[],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2016-06-24T00:00:00"}