{"id":"https://openalex.org/W774452301","doi":null,"title":"Evaluation of incentives for R&D in the pharmaceutical industry with applications for neglected diseases","display_name":"Evaluation of incentives for R&D in the pharmaceutical industry with applications for neglected diseases","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W774452301","mag":"774452301"},"language":"en","primary_location":{"id":"pmh:hdl:10068/982216","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10068/982216","pdf_url":null,"source":{"id":"https://openalex.org/S4377196900","display_name":"OpenGrey (Institut de l'Information Scientifique et Technique)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1295345811","host_organization_name":"Institut de l'Information Scientifique et Technique","host_organization_lineage":["https://openalex.org/I1295345811"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"U - Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10068/982216","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077218950","display_name":"Eshref Trushin","orcid":"https://orcid.org/0000-0001-9058-4262","observed_orcids":["https://orcid.org/0000-0001-9058-4262"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Eshref Trushin","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9058-4262","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5077218950"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11792","display_name":"Pharmaceutical Economics and Policy","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T11792","display_name":"Pharmaceutical Economics and Policy","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T12851","display_name":"Firm Innovation and Growth","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T12722","display_name":"Innovation Policy and R&D","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pharmaceutical-r-d-incentives","display_name":"pharmaceutical R&D incentives","score":0.953000009059906},{"id":"https://openalex.org/keywords/neglected-diseases","display_name":"neglected diseases","score":0.9419999718666077},{"id":"https://openalex.org/keywords/pharmaceutical-industry","display_name":"pharmaceutical industry","score":0.6169999837875366},{"id":"https://openalex.org/keywords/r-d-intensity","display_name":"R&D intensity","score":0.7440000176429749},{"id":"https://openalex.org/keywords/liquidity-constraints","display_name":"liquidity constraints","score":0.8069999814033508},{"id":"https://openalex.org/keywords/technical-efficiency","display_name":"technical efficiency","score":0.6629999876022339},{"id":"https://openalex.org/keywords/cash-flow","display_name":"cash flow","score":0.5519999861717224},{"id":"https://openalex.org/keywords/small-business","display_name":"small business","score":0.5080000162124634},{"id":"https://openalex.org/keywords/public-private-partnerships","display_name":"public-private partnerships","score":0.6150000095367432},{"id":"https://openalex.org/keywords/r-d-investment","display_name":"R&D investment","score":0.6830000281333923},{"id":"https://openalex.org/keywords/regulatory-quality","display_name":"regulatory quality","score":0.5019999742507935},{"id":"https://openalex.org/keywords/access-to-clean-water","display_name":"access to clean water","score":0.6959999799728394}],"concepts":[{"id":"https://openalex.org/C2779652045","wikidata":"https://www.wikidata.org/wiki/Q507443","display_name":"Pharmaceutical industry","level":2,"score":0.6194798350334167},{"id":"https://openalex.org/C29122968","wikidata":"https://www.wikidata.org/wiki/Q1414816","display_name":"Incentive","level":2,"score":0.6171836853027344},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.37538599967956543},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3520832061767578},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.259520560503006},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.19495359063148499},{"id":"https://openalex.org/C175444787","wikidata":"https://www.wikidata.org/wiki/Q39072","display_name":"Microeconomics","level":1,"score":0.102967768907547}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:hdl:10068/982216","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10068/982216","pdf_url":null,"source":{"id":"https://openalex.org/S4377196900","display_name":"OpenGrey (Institut de l'Information Scientifique et Technique)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1295345811","host_organization_name":"Institut de l'Information Scientifique et Technique","host_organization_lineage":["https://openalex.org/I1295345811"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"U - Thesis"},{"id":"mag:774452301","doi":null,"is_oa":false,"landing_page_url":"http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.535785","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:hdl:10068/982216","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10068/982216","pdf_url":null,"source":{"id":"https://openalex.org/S4377196900","display_name":"OpenGrey (Institut de l'Information Scientifique et Technique)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1295345811","host_organization_name":"Institut de l'Information Scientifique et Technique","host_organization_lineage":["https://openalex.org/I1295345811"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"U - Thesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5683000087738037}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":145,"referenced_works":["https://openalex.org/W49542900","https://openalex.org/W72839540","https://openalex.org/W114880134","https://openalex.org/W152876125","https://openalex.org/W180405720","https://openalex.org/W222597557","https://openalex.org/W367981682","https://openalex.org/W435676296","https://openalex.org/W588846217","https://openalex.org/W600268522","https://openalex.org/W615877575","https://openalex.org/W621402507","https://openalex.org/W648010361","https://openalex.org/W1488087725","https://openalex.org/W1492470296","https://openalex.org/W1496168364","https://openalex.org/W1498201492","https://openalex.org/W1499444096","https://openalex.org/W1500500354","https://openalex.org/W1512438225","https://openalex.org/W1517211427","https://openalex.org/W1520834119","https://openalex.org/W1526662260","https://openalex.org/W1531521080","https://openalex.org/W1535962392","https://openalex.org/W1539114728","https://openalex.org/W1546523058","https://openalex.org/W1548886407","https://openalex.org/W1563103971","https://openalex.org/W1572642704","https://openalex.org/W1586785244","https://openalex.org/W1587343623","https://openalex.org/W1589928278","https://openalex.org/W1595046345","https://openalex.org/W1595173439","https://openalex.org/W1801540244","https://openalex.org/W1802212700","https://openalex.org/W1895366050","https://openalex.org/W1944304198","https://openalex.org/W1966121766","https://openalex.org/W1970111819","https://openalex.org/W1971816555","https://openalex.org/W1974321388","https://openalex.org/W1974626579","https://openalex.org/W1976910068","https://openalex.org/W1977240483","https://openalex.org/W1977845602","https://openalex.org/W1978282661","https://openalex.org/W1978880915","https://openalex.org/W1979310720","https://openalex.org/W1982491301","https://openalex.org/W1991898766","https://openalex.org/W1999505698","https://openalex.org/W2000578291","https://openalex.org/W2004150837","https://openalex.org/W2004820580","https://openalex.org/W2006352250","https://openalex.org/W2011082753","https://openalex.org/W2013308398","https://openalex.org/W2015197765","https://openalex.org/W2020235951","https://openalex.org/W2025610165","https://openalex.org/W2029342376","https://openalex.org/W2033834012","https://openalex.org/W2036638878","https://openalex.org/W2037205178","https://openalex.org/W2040619202","https://openalex.org/W2044758663","https://openalex.org/W2046116978","https://openalex.org/W2046345129","https://openalex.org/W2053028912","https://openalex.org/W2055084783","https://openalex.org/W2059924115","https://openalex.org/W2060646203","https://openalex.org/W2063394675","https://openalex.org/W2068518739","https://openalex.org/W2072450555","https://openalex.org/W2075913967","https://openalex.org/W2079415868","https://openalex.org/W2080061756","https://openalex.org/W2082790601","https://openalex.org/W2092783476","https://openalex.org/W2094758635","https://openalex.org/W2099808721","https://openalex.org/W2104972618","https://openalex.org/W2106982823","https://openalex.org/W2111338678","https://openalex.org/W2114265987","https://openalex.org/W2115871647","https://openalex.org/W2126683408","https://openalex.org/W2129725279","https://openalex.org/W2139716534","https://openalex.org/W2141149556","https://openalex.org/W2142947341","https://openalex.org/W2143840669","https://openalex.org/W2144236517","https://openalex.org/W2144357229","https://openalex.org/W2145371590","https://openalex.org/W2148989961","https://openalex.org/W2151945084","https://openalex.org/W2158310952","https://openalex.org/W2159805452","https://openalex.org/W2162165422","https://openalex.org/W2162634300","https://openalex.org/W2166209362","https://openalex.org/W2166941765","https://openalex.org/W2167599156","https://openalex.org/W2167692381","https://openalex.org/W2167996633","https://openalex.org/W2177947568","https://openalex.org/W2178225550","https://openalex.org/W2235133800","https://openalex.org/W2326890393","https://openalex.org/W2409651194","https://openalex.org/W2483759920","https://openalex.org/W2568908347","https://openalex.org/W2752617332","https://openalex.org/W2790332046","https://openalex.org/W2803072236","https://openalex.org/W2889872593","https://openalex.org/W2891211072","https://openalex.org/W3021983119","https://openalex.org/W3121155372","https://openalex.org/W3121276525","https://openalex.org/W3121516428","https://openalex.org/W3121666914","https://openalex.org/W3122061504","https://openalex.org/W3122338549","https://openalex.org/W3123071502","https://openalex.org/W3123271837","https://openalex.org/W3123622630","https://openalex.org/W3123749329","https://openalex.org/W3123783630","https://openalex.org/W3124046399","https://openalex.org/W3124114405","https://openalex.org/W3124284666","https://openalex.org/W3124422916","https://openalex.org/W3124757459","https://openalex.org/W3124895281","https://openalex.org/W3125057276","https://openalex.org/W3125140669","https://openalex.org/W3125419750","https://openalex.org/W3125628358","https://openalex.org/W3125712117","https://openalex.org/W3146166473"],"related_works":["https://openalex.org/W1608225023","https://openalex.org/W784809989","https://openalex.org/W1001167483","https://openalex.org/W179802027","https://openalex.org/W7043524411","https://openalex.org/W1490463169","https://openalex.org/W7061939474","https://openalex.org/W7001252330","https://openalex.org/W1978133503","https://openalex.org/W119439686"],"abstract_inverted_index":{"This":[0],"thesis":[1],"is":[2],"concerned":[3],"with":[4,90,111,158],"the":[5,25,43,61,85,128,147,193,198,201,220,251,261],"development":[6],"of":[7,24,53,56,69,102,130,136,164,175,200,206,219,226,253,264],"incentives":[8,231],"for":[9,13,60,125,209,247],"pharmaceutical":[10,58,65,173],"R&D,":[11],"specifically":[12],"neglected":[14,202,210],"diseases.":[15],"The":[16,21,47,80,133],"following":[17],"approaches":[18],"are":[19,45,87,109,121,232],"adopted.":[20],"short-term":[22],"effects":[23,83],"recent":[26],"cost-containment":[27,151],"reforms":[28],"on":[29,84,105,172,182,213,235,260],"seven":[30],"financial":[31,54],"indicators":[32,141],"related":[33],"to":[34,143,155,187,191,228],"firms\u2018":[35],"R&D":[36,106,140,162,174,207,249],"in":[37,197,250],"Denmark,":[38],"Germany,":[39],"France,":[40],"Japan,":[41],"and":[42,73,96,107,123,177,223,271],"US":[44],"estimated.":[46],"dataset":[48],"represents":[49],"a":[50,169,224,241,254],"panel":[51,113],"data":[52],"statements":[55],"1306":[57],"firms":[59,266],"period":[62],"1997-2007.":[63],"National":[64],"expenditures,":[66],"population,":[67],"availability":[68],"credit,":[70],"patent":[71],"applications,":[72],"regulatory":[74,148],"quality":[75],"have":[76,239],"been":[77],"controlled":[78],"for.":[79],"average":[81],"treatment":[82],"treated":[86],"econometrically":[88],"estimated":[89,110,122],"before-after":[91],"comparisons,":[92],"two":[93],"difference-in-differences":[94],"(DiD)":[95],"three":[97],"matching":[98],"DiD":[99],"methods.":[100,114],"Impacts":[101],"liquidity":[103],"constraints":[104],"investment":[108],"dynamic":[112],"Using":[115],"frontier":[116],"modelling,":[117],"technical":[118,159],"production":[119],"inefficiencies":[120],"tested":[124],"independence":[126],"from":[127],"stringency":[129],"national":[131],"regulation.":[132],"major":[134],"findings":[135],"this":[137,236],"dissertation":[138],"are:":[139],"tend":[142],"be":[144,156,192],"persistent":[145],"despite":[146],"changes;":[149],"tighter":[150],"regulations":[152],"appear":[153],"not":[154,181],"associated":[157],"efficiency":[160],"or":[161],"intensity":[163],"firms;":[165],"cash":[166],"flow":[167],"has":[168],"positive":[170],"effect":[171],"small":[176,265],"young":[178],"firms,":[179],"but":[180],"physical":[183],"investment.":[184],"Improved":[185],"access":[186],"clean":[188],"water":[189],"appears":[190],"most":[194],"important":[195],"factor":[196],"reduction":[199],"diseases\u2018":[203],"burden;":[204],"evaluation":[205],"schemes":[208],"diseases":[211],"based":[212],"17":[214],"criteria":[215],"indicates":[216],"insufficient":[217],"performance":[218],"existing":[221],"proposals":[222],"number":[225],"recommendations":[227],"design":[229],"better":[230],"substantiated.":[233],"Based":[234],"analysis,":[237],"I":[238],"designed":[240],"new":[242],"hybrid":[243],"public-private":[244],"partnership":[245],"model":[246],"financing":[248],"form":[252],"prize":[255],"screening":[256],"mechanism,":[257],"which":[258],"relies":[259],"innovative":[262],"effort":[263],"by":[267],"reducing":[268],"entry":[269],"barriers":[270],"moral":[272],"hazard":[273],"problems.":[274]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}