{"id":"https://openalex.org/W7743040","doi":"https://doi.org/10.33588/rn.3608.2002521","title":"Convulsiones y hemorragia subaracnoidea tras exposici\u00f3n a paroxetina in utero","display_name":"Convulsiones y hemorragia subaracnoidea tras exposici\u00f3n a paroxetina in utero","publication_year":2003,"publication_date":"2003-01-01","ids":{"openalex":"https://openalex.org/W7743040","doi":"https://doi.org/10.33588/rn.3608.2002521","mag":"7743040","pmid":"https://pubmed.ncbi.nlm.nih.gov/12717649"},"language":"es","primary_location":{"id":"doi:10.33588/rn.3608.2002521","doi":"https://doi.org/10.33588/rn.3608.2002521","is_oa":false,"landing_page_url":"https://doi.org/10.33588/rn.3608.2002521","pdf_url":null,"source":{"id":"https://openalex.org/S184263677","display_name":"Revista de Neurolog\u00eda","issn_l":"0210-0010","issn":["0210-0010","1576-6578"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4322632785","host_organization_name":"Viguera Publishers","host_organization_lineage":["https://openalex.org/P4322632785"],"host_organization_lineage_names":["Viguera Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista de Neurolog\u00eda","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035862556","display_name":"Mar\u00eda Dolors Salvia Roig\u00e9s","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M\u00aa Dolors Salvia Roig\u00e9s","raw_affiliation_strings":["Servei de Neonatologia, Institut Clinic de Ginecologia, Obstetricia, i Neonatologia, Unitat Integrada de Pediatria, (ICGON), Barcelona, Espa\u00f1a"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Servei de Neonatologia, Institut Clinic de Ginecologia, Obstetricia, i Neonatologia, Unitat Integrada de Pediatria, (ICGON), Barcelona, Espa\u00f1a","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112332123","display_name":"Llu\u00efsa Garc\u00eda Esteve","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Llu\u00efsa Garcia Esteve","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011582125","display_name":"Anna Gonc\u00e9 Mellgren","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anna Gonc\u00e9 Mellgren","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009027441","display_name":"Ma Teresa Esqu\u00e9 Ruiz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M\u00aa Teresa Esqu\u00e9 Ruiz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067014211","display_name":"J. Figueras Aloy","orcid":"https://orcid.org/0000-0003-1261-8193","observed_orcids":["https://orcid.org/0000-0003-1261-8193"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Josep Figueras Aloy","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5037975208","display_name":"Xavier Carbonell i Estrany","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xavier Carbonell Estrany","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.9879,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.90190337,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"36","issue":"08","first_page":"724","last_page":"724"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11964","display_name":"Pregnancy and Medication Impact","score":0.6859999895095825,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11964","display_name":"Pregnancy and Medication Impact","score":0.6859999895095825,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11633","display_name":"Prenatal Substance Exposure Effects","score":0.156700000166893,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10786","display_name":"Maternal Mental Health During Pregnancy and Postpartum","score":0.05350000038743019,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/paroxetine","display_name":"paroxetine","score":0.9940000176429749},{"id":"https://openalex.org/keywords/selective-serotonin-reuptake-inhibitors","display_name":"selective serotonin reuptake inhibitors","score":0.9129999876022339},{"id":"https://openalex.org/keywords/prenatal-drug-exposure","display_name":"prenatal drug exposure","score":0.7730000019073486},{"id":"https://openalex.org/keywords/neonatal-seizures","display_name":"neonatal seizures","score":0.8759999871253967},{"id":"https://openalex.org/keywords/subarachnoid-hemorrhage","display_name":"subarachnoid hemorrhage","score":0.9229999780654907},{"id":"https://openalex.org/keywords/third-trimester","display_name":"third trimester","score":0.8579999804496765},{"id":"https://openalex.org/keywords/serotonin-depletion","display_name":"serotonin depletion","score":0.46799999475479126},{"id":"https://openalex.org/keywords/platelet-serotonin","display_name":"platelet serotonin","score":0.7110000252723694},{"id":"https://openalex.org/keywords/seizure-threshold","display_name":"seizure threshold","score":0.6449999809265137},{"id":"https://openalex.org/keywords/neonatal-follow-up","display_name":"neonatal follow-up","score":0.49000000953674316}],"concepts":[{"id":"https://openalex.org/C2777828372","wikidata":"https://www.wikidata.org/wiki/Q408471","display_name":"Paroxetine","level":4,"score":0.856088399887085},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8298746347427368},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.6728361248970032},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.5312673449516296},{"id":"https://openalex.org/C2777736543","wikidata":"https://www.wikidata.org/wiki/Q693442","display_name":"Subarachnoid hemorrhage","level":2,"score":0.49660617113113403},{"id":"https://openalex.org/C137627325","wikidata":"https://www.wikidata.org/wiki/Q156318","display_name":"Etiology","level":2,"score":0.47892794013023376},{"id":"https://openalex.org/C201614185","wikidata":"https://www.wikidata.org/wiki/Q396833","display_name":"In utero","level":4,"score":0.4575892686843872},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.390566885471344},{"id":"https://openalex.org/C2775864247","wikidata":"https://www.wikidata.org/wiki/Q167934","display_name":"Serotonin","level":3,"score":0.3746110498905182},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.3249611258506775},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.29028427600860596},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.21844148635864258},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011263","descriptor_name":"Pregnancy Trimester, Third","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012640","descriptor_name":"Seizures","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D013345","descriptor_name":"Subarachnoid Hemorrhage","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D017367","descriptor_name":"Selective Serotonin Reuptake Inhibitors","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D017374","descriptor_name":"Paroxetine","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.33588/rn.3608.2002521","doi":"https://doi.org/10.33588/rn.3608.2002521","is_oa":false,"landing_page_url":"https://doi.org/10.33588/rn.3608.2002521","pdf_url":null,"source":{"id":"https://openalex.org/S184263677","display_name":"Revista de Neurolog\u00eda","issn_l":"0210-0010","issn":["0210-0010","1576-6578"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4322632785","host_organization_name":"Viguera Publishers","host_organization_lineage":["https://openalex.org/P4322632785"],"host_organization_lineage_names":["Viguera Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista de Neurolog\u00eda","raw_type":"journal-article"},{"id":"pmid:12717649","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12717649","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista de neurologia","raw_type":"Case Reports"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2030887516","https://openalex.org/W2410791986","https://openalex.org/W2014214015","https://openalex.org/W1598477096","https://openalex.org/W2148543038","https://openalex.org/W2118825823","https://openalex.org/W83339188","https://openalex.org/W2154599798","https://openalex.org/W1965826735","https://openalex.org/W2153939195"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Selective":[1],"serotonin":[2,166],"reuptake":[3],"inhibitors":[4],"(SSRIs)":[5],"are":[6,59],"often":[7],"used":[8,24],"as":[9],"antidepressants":[10],"in":[11,25,45,95,152,180,183,196,209],"pregnant":[12],"women.":[13],"SSRIs":[14],"do":[15],"not":[16,30,105],"appear":[17],"to":[18,61,71,161,176],"increase":[19],"the":[20,39,53,62,96,128,132,137,149,171,197,210],"teratogenic":[21],"risk":[22,40],"when":[23],"their":[26],"recommended":[27],"doses.":[28],"However,":[29],"enough":[31],"information":[32],"is":[33,126,215],"available":[34],"at":[35],"this":[36],"time":[37],"about":[38],"of":[41,56,100,108,164,200,206,213],"toxicity":[42],"and":[43,92,167,178,188],"complications":[44],"newborns,":[46],"after":[47,193],"mother":[48,80],"treatment":[49,195],"with":[50,68,84,155],"SSRI":[51],"during":[52,88,140],"third":[54,198],"trimester":[55,199],"pregnancy.":[57,201],"We":[58],"limited":[60],"existing":[63],"reports":[64],"that":[65,127],"describe":[66],"newborns":[67,208],"symptoms":[69,107],"due":[70,160,175],"hyperserotoninemia":[72],"or":[73,119,182],"withdrawal.":[74],"CASE":[75],"REPORT:":[76],"One":[77],"newborn":[78,103],"whose":[79],"had":[81],"been":[82],"treated":[83],"paroxetine":[85,129,177,194],"20":[86],"mg/day":[87],"pregnancy,":[89],"presented":[90],"convulsions":[91,187],"subarachnoid":[93,150,189],"haemorrhage":[94,151,190],"first":[97,138],"six":[98],"hours":[99],"life.":[101],"The":[102,122,142],"did":[104],"present":[106],"hypoxic":[109],"ischaemic":[110],"encephalopathy,":[111],"withdrawal":[112],"syndrome,":[113],"infection,":[114],"metabolic":[115],"alterations,":[116],"cerebral":[117],"malformations":[118],"coagulopaties.":[120],"DISCUSSION:":[121],"most":[123],"probable":[124],"etiology":[125],"could":[130],"decrease":[131],"seizure":[133,139],"threshold,":[134],"taking":[135],"place":[136],"delivery.":[141],"difficult":[143],"fetal":[144],"extraction":[145],"would":[146],"have":[147],"provoked":[148],"a":[153,162],"patient":[154],"an":[156],"impaired":[157],"haemostatic":[158],"function":[159],"depletion":[163],"platelet":[165],"may":[168,191],"also":[169],"contribute":[170],"increased":[172],"vascular":[173],"fragility":[174],"reported":[179],"adults":[181],"animals.":[184],"CONCLUSION:":[185],"Neonatal":[186],"occur":[192],"An":[202],"accurate":[203],"follow":[204],"up":[205],"these":[207],"firsts":[211],"days":[212],"life":[214],"strongly":[216],"recommended.":[217]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}