{"id":"https://openalex.org/W77354397","doi":null,"title":"Abstract 1767: Mice Lacking Smad3 are Protected against Angiotensin II-Induced Cardiac Inflammation and Fibrosis","display_name":"Abstract 1767: Mice Lacking Smad3 are Protected against Angiotensin II-Induced Cardiac Inflammation and Fibrosis","publication_year":2008,"publication_date":"2008-10-28","ids":{"openalex":"https://openalex.org/W77354397","mag":"77354397"},"language":"en","primary_location":{"id":"mag:77354397","doi":null,"is_oa":false,"landing_page_url":"http://circ.ahajournals.org/cgi/content/meeting_abstract/118/18_MeetingAbstracts/S_385-b","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Circulation","raw_type":null},"volume":null,"type":"conference-abstract","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061472855","display_name":"Hui Y. Lan","orcid":"https://orcid.org/0000-0003-4283-9755","observed_orcids":["https://orcid.org/0000-0003-4283-9755"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hui Y. Lan","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4283-9755","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103460798","display_name":"Xiao Ru Huang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xiao Ru Huang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066269765","display_name":"Arthur C.K. Chung","orcid":"https://orcid.org/0000-0003-1519-7224","observed_orcids":["https://orcid.org/0000-0003-1519-7224"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Arthur C.K. Chung","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1519-7224","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102426302","display_name":"Fuye Yang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fuye Yang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Li Zhou","orcid":"https://orcid.org/0000-0001-8942-1976","observed_orcids":["https://orcid.org/0000-0001-8942-1976"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Li Zhou","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8942-1976","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050911555","display_name":"Chu\u2010Xia Deng","orcid":"https://orcid.org/0000-0001-8033-3902","observed_orcids":["https://orcid.org/0000-0001-8033-3902","https://orcid.org/0000-0003-0031-9962"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chu\u2010Xia Deng","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8033-3902","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074031560","display_name":"Hung\u2010Fat Tse","orcid":"https://orcid.org/0000-0003-4665-7887","observed_orcids":["https://orcid.org/0000-0003-4665-7887"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hung\u2010Fat Tse","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4665-7887","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5004139461","display_name":"Chu\u2010Pak Lau","orcid":"https://orcid.org/0000-0002-3526-8950","observed_orcids":["https://orcid.org/0000-0002-3526-8950"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chu\u2010Pak Lau","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3526-8950","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"118","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.9413999915122986,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.9413999915122986,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11001","display_name":"Renin-Angiotensin System Studies","score":0.047600001096725464,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11501","display_name":"TGF-\u03b2 signaling in diseases","score":0.0071000000461936,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/smad3","display_name":"Smad3","score":0.9900000095367432},{"id":"https://openalex.org/keywords/angiotensin-ii","display_name":"angiotensin II","score":0.9810000061988831},{"id":"https://openalex.org/keywords/cardiac-inflammation","display_name":"cardiac inflammation","score":0.9810000061988831},{"id":"https://openalex.org/keywords/myocardial-fibrosis","display_name":"myocardial fibrosis","score":0.9950000047683716},{"id":"https://openalex.org/keywords/smad3-knockout-mice","display_name":"Smad3 knockout mice","score":0.7519999742507935},{"id":"https://openalex.org/keywords/renin-angiotensin-system","display_name":"renin-angiotensin system","score":0.7950000166893005},{"id":"https://openalex.org/keywords/heart-failure","display_name":"heart failure","score":0.34299999475479126}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9362045526504517},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.8214078545570374},{"id":"https://openalex.org/C2780559512","wikidata":"https://www.wikidata.org/wiki/Q605709","display_name":"Fibrosis","level":2,"score":0.7617651224136353},{"id":"https://openalex.org/C2908929049","wikidata":"https://www.wikidata.org/wiki/Q65963433","display_name":"Angiotensin II","level":3,"score":0.7069324851036072},{"id":"https://openalex.org/C2777420927","wikidata":"https://www.wikidata.org/wiki/Q5038318","display_name":"Cardiac fibrosis","level":3,"score":0.6081666350364685},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3345317244529724},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3335581421852112},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.13478916883468628}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:77354397","doi":null,"is_oa":false,"landing_page_url":"http://circ.ahajournals.org/cgi/content/meeting_abstract/118/18_MeetingAbstracts/S_385-b","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Circulation","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.4000000059604645,"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1998988555","https://openalex.org/W2255455703","https://openalex.org/W7100205613","https://openalex.org/W7096917206","https://openalex.org/W2887263559","https://openalex.org/W2158923104","https://openalex.org/W1573139808","https://openalex.org/W3142412136","https://openalex.org/W1016563797","https://openalex.org/W1989711100"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-06-24T00:00:00"}