{"id":"https://openalex.org/W769064571","doi":null,"title":"Estresse oxidativo, altera\u00e7\u00f5es metab\u00f3licas e renais decorrentes da elevada ingest\u00e3o de sacarose: efeito protetor da N-acetilciste\u00edna (NAC)","display_name":"Estresse oxidativo, altera\u00e7\u00f5es metab\u00f3licas e renais decorrentes da elevada ingest\u00e3o de sacarose: efeito protetor da N-acetilciste\u00edna (NAC)","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W769064571","mag":"769064571"},"language":"pt","primary_location":{"id":"pmh:oai:repositorio.unesp.br:11449/118121","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11449/118121","pdf_url":"http://hdl.handle.net/11449/118121","source":{"id":"https://openalex.org/S4377196277","display_name":"UNESP Institutional Repository (S\u00e3o Paulo State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I879563668","host_organization_name":"Universidade Estadual Paulista (Unesp)","host_organization_lineage":["https://openalex.org/I879563668"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/bachelorThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/11449/118121","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050850412","display_name":"Helo\u00edsa Balan Assalin","orcid":"https://orcid.org/0000-0003-1269-9624","observed_orcids":["https://orcid.org/0000-0003-1269-9624"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Helo\u00edsa Balan Assalin","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1269-9624","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5050850412"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12964","display_name":"Diet, Metabolism, and Disease","score":0.5702999830245972,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12964","display_name":"Diet, Metabolism, and Disease","score":0.5702999830245972,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.33180001378059387,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.02319999970495701,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.7599999904632568},{"id":"https://openalex.org/keywords/n-acetylcysteine","display_name":"N-acetylcysteine","score":0.9200000166893005},{"id":"https://openalex.org/keywords/antioxidants","display_name":"antioxidants","score":0.6830000281333923},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.8450000286102295},{"id":"https://openalex.org/keywords/diabetic-nephropathy","display_name":"diabetic nephropathy","score":0.9929999709129333},{"id":"https://openalex.org/keywords/oral-glucose-tolerance-test","display_name":"oral glucose tolerance test","score":0.7289999723434448},{"id":"https://openalex.org/keywords/resting-metabolic-rate","display_name":"resting metabolic rate","score":0.8640000224113464},{"id":"https://openalex.org/keywords/substrate-oxidation","display_name":"substrate oxidation","score":0.7480000257492065},{"id":"https://openalex.org/keywords/respiratory-quotient","display_name":"respiratory quotient","score":0.8389999866485596},{"id":"https://openalex.org/keywords/renal-function","display_name":"renal function","score":0.6949999928474426},{"id":"https://openalex.org/keywords/fasting-blood-glucose","display_name":"fasting blood glucose","score":0.640999972820282},{"id":"https://openalex.org/keywords/sucrose-induced-hyperglycemia","display_name":"sucrose-induced hyperglycemia","score":0.5540000200271606},{"id":"https://openalex.org/keywords/rats","display_name":"rats","score":0.32600000500679016}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3993430733680725},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3918672204017639}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:repositorio.unesp.br:11449/118121","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11449/118121","pdf_url":"http://hdl.handle.net/11449/118121","source":{"id":"https://openalex.org/S4377196277","display_name":"UNESP Institutional Repository (S\u00e3o Paulo State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I879563668","host_organization_name":"Universidade Estadual Paulista (Unesp)","host_organization_lineage":["https://openalex.org/I879563668"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/bachelorThesis"},{"id":"pmh:oai:acervodigital.unesp.br:11449/118121","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11449/118121","pdf_url":null,"source":{"id":"https://openalex.org/S4306400256","display_name":"Acervo Digital da Universidade Estadual Paulista (Universidade Estadual Paulista)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210115194","host_organization_name":"Funda\u00e7\u00e3o para o Desenvolvimento da UNESP","host_organization_lineage":["https://openalex.org/I4210115194"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"outro"},{"id":"mag:769064571","doi":null,"is_oa":false,"landing_page_url":"http://repositorio.unesp.br/handle/11449/118121","pdf_url":null,"source":{"id":"https://openalex.org/S4210186100","display_name":"Aleph UCLA Undergraduate Research Journal for the Humanities and Social Sciences","issn_l":"2639-6440","issn":["2639-6440","2639-6459"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Aleph UCLA Undergraduate Research Journal for the Humanities and Social Sciences","raw_type":null}],"best_oa_location":{"id":"pmh:oai:repositorio.unesp.br:11449/118121","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11449/118121","pdf_url":"http://hdl.handle.net/11449/118121","source":{"id":"https://openalex.org/S4377196277","display_name":"UNESP Institutional Repository (S\u00e3o Paulo State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I879563668","host_organization_name":"Universidade Estadual Paulista (Unesp)","host_organization_lineage":["https://openalex.org/I879563668"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/bachelorThesis"},"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W769064571.pdf","grobid_xml":"https://content.openalex.org/works/W769064571.grobid-xml"},"referenced_works_count":66,"referenced_works":["https://openalex.org/W1550111394","https://openalex.org/W1757232958","https://openalex.org/W1783771610","https://openalex.org/W1819496837","https://openalex.org/W1936765564","https://openalex.org/W1964851344","https://openalex.org/W1966023606","https://openalex.org/W1971336430","https://openalex.org/W1974607287","https://openalex.org/W1977498227","https://openalex.org/W1980295850","https://openalex.org/W1983956013","https://openalex.org/W1984579726","https://openalex.org/W1993490769","https://openalex.org/W1995317658","https://openalex.org/W1995992894","https://openalex.org/W2001265042","https://openalex.org/W2005246339","https://openalex.org/W2021550936","https://openalex.org/W2025433846","https://openalex.org/W2026437193","https://openalex.org/W2027079316","https://openalex.org/W2028542675","https://openalex.org/W2028694490","https://openalex.org/W2030625746","https://openalex.org/W2034751609","https://openalex.org/W2038667359","https://openalex.org/W2038941282","https://openalex.org/W2039752142","https://openalex.org/W2040904881","https://openalex.org/W2041391173","https://openalex.org/W2047674176","https://openalex.org/W2047867444","https://openalex.org/W2048395055","https://openalex.org/W2050161856","https://openalex.org/W2053293301","https://openalex.org/W2078843599","https://openalex.org/W2078974726","https://openalex.org/W2080454816","https://openalex.org/W2091456382","https://openalex.org/W2092699838","https://openalex.org/W2093960743","https://openalex.org/W2100371568","https://openalex.org/W2108702111","https://openalex.org/W2111230462","https://openalex.org/W2120180111","https://openalex.org/W2122166221","https://openalex.org/W2122648697","https://openalex.org/W2123766698","https://openalex.org/W2124098523","https://openalex.org/W2124427457","https://openalex.org/W2124733230","https://openalex.org/W2134727078","https://openalex.org/W2136913126","https://openalex.org/W2148109667","https://openalex.org/W2152593520","https://openalex.org/W2156044622","https://openalex.org/W2161849974","https://openalex.org/W2170036297","https://openalex.org/W2184009989","https://openalex.org/W2229569748","https://openalex.org/W2266860018","https://openalex.org/W2338357348","https://openalex.org/W2339941831","https://openalex.org/W2406292281","https://openalex.org/W2471605942"],"related_works":["https://openalex.org/W2789065401","https://openalex.org/W6980249780","https://openalex.org/W1980493052","https://openalex.org/W7120455068","https://openalex.org/W7120701332","https://openalex.org/W7120277885","https://openalex.org/W2041029983","https://openalex.org/W2124828104","https://openalex.org/W4391030625","https://openalex.org/W2382172029"],"abstract_inverted_index":{"Oxidative":[0],"stress":[1],"is":[2,281],"related":[3],"with":[4,12,178],"physiopathology":[5],"of":[6,23,31,64,124,140,153,182,193,201,222,276],"diabetes":[7],"mellitus":[8],"type":[9],"II":[10],"and":[11,43,46,49,55,61,90,98,111,114,134,145,159,170,173,186,203,210,244,257,264,269,285,292],"its":[13,102,118],"secondary":[14],"complications,":[15],"such":[16],"as":[17],"diabetic":[18],"nephropathy.":[19],"Thus,":[20],"the":[21,29,77,171,198,223,273],"purpose":[22],"this":[24],"study":[25],"was":[26],"to":[27,86,129,242,290],"examine":[28],"effects":[30],"n-acetylcysteine":[32],"NAC,":[33],"an":[34,164],"antioxidant":[35],"from":[36,143],"Allium":[37],"cepa,":[38],"on":[39],"oxidative":[40],"stress,":[41],"morphometrical":[42],"nutritional":[44],"parameters":[45],"basal":[47],"metabolism":[48],"energetic":[50],"substrate":[51],"utilization,":[52],"serum":[53],"glucose":[54,57,194,280],"oral":[56],"tolerance":[58],"test":[59],"(OGTT),":[60],"renal":[62],"function":[63],"high-sucrose":[65],"intake":[66],"rats.":[67],"Animals":[68,200],"were":[69,82,127,148,162,176],"initially":[70],"divided":[71,149],"into":[72,150],"three":[73],"groups.":[74],"Rats":[75],"in":[76,101,117,132,262,283],"control":[78],"group":[79,94,107,234,249,296],"(C;":[80],"n=10)":[81,93],"given":[83,163],"free":[84],"access":[85,311],"a":[87,179,190],"standard":[88,96,109],"chow":[89,97,110],"water;":[91,104],"(S;":[92],"received":[95,108,189],"30%":[99,115],"sucrose":[100,116],"drinking":[103,119],"(SN;":[105],"n=5)":[106],"2g/L":[112],"NAC":[113,184],"water.":[120],"After":[121,137],"25":[122],"days":[123,139],"treatments,":[125,141],"rats":[126,142,155],"submitted":[128],"indirect":[130],"calorimetry":[131],"fasted":[133,263],"feed":[135,265],"states.":[136],"30":[138,301],"C":[144,215,243,268],"S":[146,202,233,248],"groups":[147,152,161,175,205],"four":[151],"five":[154],"each.":[156],"The":[157],"(CC)":[158],"(SS)":[160],"intra-gastric":[165,180,191],"dose":[166,181,192],"0,6mL":[167,183],"saline":[168],"(0,9%NaCl)":[169],"(CNAC)":[172],"(SNAC)":[174],"treated":[177],"(160g/day),":[185],"then":[187],"everybody":[188],"solution":[195],"(20%)":[196],"for":[197],"OGTT.":[199],"SN":[204,245,270,295],"have":[206,235],"higher":[207,251,254],"liquid":[208],"consumption":[209,213],"lower":[211,236,258],"food":[212],"than":[214,267],"group.":[216],"Calorimetric":[217],"analyses":[218],"confirm":[219],"that":[220],"despite":[221],"final":[224],"body":[225],"weight":[226],"had":[227],"not":[228],"statistical":[229],"difference":[230],"among":[231],"groups,":[232,271],"resting":[237],"metabolic":[238],"rate":[239],"when":[240,288,306],"compared":[241,289],"animals.":[246],"Besides,":[247],"has":[250,297],"respiratory":[252],"quotient,":[253],"carbohydrate":[255],"oxidation":[256],"lipid":[259],"oxidation,":[260],"both":[261],"states,":[266],"evidencing":[272],"beneficial":[274],"effect":[275],"NAC.":[277],"Fasting":[278],"plasma":[279],"increased":[282],"SS":[284],"SNAC":[286],"animals":[287],"CC":[291],"CNAC,":[293],"however":[294],"glicemic":[298],"level":[299],"at":[300],"min":[302],"before":[303],"OGTT":[304],"decreased":[305],"...(Complete":[307],"abstract":[308],"click":[309],"electronic":[310],"below)":[312]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}