{"id":"https://openalex.org/W7684092","doi":null,"title":"Compliance in gout patients.","display_name":"Compliance in gout patients.","publication_year":2010,"publication_date":"2010-10-01","ids":{"openalex":"https://openalex.org/W7684092","mag":"7684092","pmid":"https://pubmed.ncbi.nlm.nih.gov/21245815"},"language":"en","primary_location":{"id":"pmid:21245815","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21245815","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta reumatologica portuguesa","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018393166","display_name":"L Silva","orcid":"https://orcid.org/0000-0003-0245-0745","observed_orcids":["https://orcid.org/0000-0003-0245-0745"]},"institutions":[{"id":"https://openalex.org/I182534213","display_name":"Universidade do Porto","ror":"https://ror.org/043pwc612","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213"]},{"id":"https://openalex.org/I3018176973","display_name":"Hospital de S\u00e3o Jo\u00e3o","ror":"https://ror.org/04qsnc772","country_code":"PT","type":"healthcare","lineage":["https://openalex.org/I3018176973"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"L Silva","raw_affiliation_strings":["Rheumatology Department, Hospital de S\u00e3o Jo\u00e3o, Universidade do Porto, Portugal. ligia1silva@yahoo.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rheumatology Department, Hospital de S\u00e3o Jo\u00e3o, Universidade do Porto, Portugal. ligia1silva@yahoo.com","institution_ids":["https://openalex.org/I182534213","https://openalex.org/I3018176973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047578354","display_name":"Eugenio de Miguel","orcid":"https://orcid.org/0000-0001-5146-1964","observed_orcids":["https://orcid.org/0000-0001-5146-1964"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eugenio De Miguel","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020459487","display_name":"Diana Peiteado","orcid":"https://orcid.org/0000-0002-6953-409X","observed_orcids":["https://orcid.org/0000-0002-6953-409X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Diana Peiteado","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111932749","display_name":"Alejandro Villalba","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alejandro Villalba","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012664000","display_name":"Martin Mola","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Martin Mola","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066204308","display_name":"Jos\u00e9 Pinto","orcid":"https://orcid.org/0000-0001-8682-7559","observed_orcids":["https://orcid.org/0000-0001-8682-7559"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jos\u00e3 Pinto","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5006164560","display_name":"Francisco Ventura","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Francisco S Ventura","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.696,"has_fulltext":false,"cited_by_count":28,"citation_normalized_percentile":{"value":0.88655041,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"35","issue":"5","first_page":"466","last_page":"74"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11139","display_name":"Gout, Hyperuricemia, Uric Acid","score":0.9721999764442444,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11139","display_name":"Gout, Hyperuricemia, Uric Acid","score":0.9721999764442444,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11620","display_name":"Medication Adherence and Compliance","score":0.024299999698996544,"subfield":{"id":"https://openalex.org/subfields/2714","display_name":"Family Practice"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gout","display_name":"gout","score":0.9909999966621399},{"id":"https://openalex.org/keywords/treatment-nonadherence","display_name":"treatment non-adherence","score":0.6899999976158142},{"id":"https://openalex.org/keywords/treatment-adherence","display_name":"medication adherence","score":0.8050000071525574},{"id":"https://openalex.org/keywords/gout-flares","display_name":"gout flares","score":0.7820000052452087},{"id":"https://openalex.org/keywords/serum-uric-acid","display_name":"serum uric acid","score":0.9629999995231628},{"id":"https://openalex.org/keywords/hyperuricosuria","display_name":"hyperuricosuria","score":0.8299999833106995},{"id":"https://openalex.org/keywords/kidney-stones","display_name":"kidney stones","score":0.9980000257492065},{"id":"https://openalex.org/keywords/kidney-failure","display_name":"renal failure","score":0.9419999718666077},{"id":"https://openalex.org/keywords/allopurinol","display_name":"allopurinol","score":0.8169999718666077},{"id":"https://openalex.org/keywords/nonsteroidal-anti-inflammatory-drugs","display_name":"nonsteroidal anti-inflammatory drugs","score":0.6919999718666077},{"id":"https://openalex.org/keywords/benzbromarone","display_name":"benzbromarone","score":0.7870000004768372},{"id":"https://openalex.org/keywords/corticosteroids","display_name":"corticosteroids","score":0.8379999995231628},{"id":"https://openalex.org/keywords/disease-duration","display_name":"disease duration","score":0.5799999833106995},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":0.9070000052452087},{"id":"https://openalex.org/keywords/age","display_name":"age","score":0.6230000257492065}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9749048948287964},{"id":"https://openalex.org/C2780402116","wikidata":"https://www.wikidata.org/wiki/Q133087","display_name":"Gout","level":2,"score":0.9512045979499817},{"id":"https://openalex.org/C2780261098","wikidata":"https://www.wikidata.org/wiki/Q412486","display_name":"Allopurinol","level":2,"score":0.6843631267547607},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6639681458473206},{"id":"https://openalex.org/C198451711","wikidata":"https://www.wikidata.org/wiki/Q327657","display_name":"Rheumatology","level":2,"score":0.6417567729949951},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.5132350921630859},{"id":"https://openalex.org/C2781460075","wikidata":"https://www.wikidata.org/wiki/Q1399332","display_name":"Compliance (psychology)","level":2,"score":0.4819905161857605},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4636583924293518},{"id":"https://openalex.org/C2779881121","wikidata":"https://www.wikidata.org/wiki/Q105522","display_name":"Uric acid","level":2,"score":0.4590986371040344},{"id":"https://openalex.org/C2780932893","wikidata":"https://www.wikidata.org/wiki/Q417296","display_name":"Febuxostat","level":4,"score":0.43226560950279236},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3967933654785156},{"id":"https://openalex.org/C2779721657","wikidata":"https://www.wikidata.org/wiki/Q49970","display_name":"Hyperuricemia","level":3,"score":0.2897935211658478},{"id":"https://openalex.org/C77805123","wikidata":"https://www.wikidata.org/wiki/Q161272","display_name":"Social psychology","level":1,"score":0.0},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006073","descriptor_name":"Gout","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010349","descriptor_name":"Patient Compliance","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:21245815","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21245815","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta reumatologica portuguesa","raw_type":"Journal Article"},{"id":"mag:7684092","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21245815","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4409766658","https://openalex.org/W1965212373","https://openalex.org/W2469565678","https://openalex.org/W4402585776","https://openalex.org/W1985396515","https://openalex.org/W1749728700","https://openalex.org/W2332092091","https://openalex.org/W2345940854","https://openalex.org/W2262127071","https://openalex.org/W1982703566"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Despite":[1],"its":[2,33],"relative":[3],"high":[4],"prevalence,potential":[5],"devastating":[6],"clinical":[7,70,146,338,391],"consequences":[8],"and":[9,20,29,32,75,90,107,162,165,182,218,220,235,237,243,259,291,304,317,340,345,376,389],"socio-economic":[10],"impact,":[11],"the":[12,21,40,44,69,100,108,139,221,246,263,347,402,407,413],"existence":[13],"of":[14,47,64,73,87,125,141,144,152,158,191,214,223,256,266,280,315,349,362,368,410,412],"effective":[15],"drugs":[16],"to":[17,49,59,79,94,99,155,160,170,228,285,297,313,326,406],"treat":[18],"it,":[19],"well":[22],"recognised":[23],"direct":[24],"relation":[25],"between":[26,200,336,357],"acute":[27],"flares":[28,258],"treatment":[30,208],"interruptions":[31],"resumption,":[34],"gout":[35,96,105,112,172,257,286],"is":[36,55,384],"still":[37],"often":[38,231,239,300,306],"considered":[39],"chronic":[41],"disease":[42,277],"with":[43,148,209,233,241,275,302,308,359],"worst":[45,363],"rate":[46,255,367],"adherence":[48],"therapy.":[50],"The":[51,381],"reason":[52],"for":[53,104,111,129,273,378],"this":[54],"unknown.":[56],"We":[57,83,195],"proposed":[58],"thoroughly":[60],"evaluate":[61],"a":[62,85,119,188,271,355,387],"subgroup":[63],"patients,":[65],"aiming":[66],"at":[67],"identifying":[68],"features":[71,147,339],"predictive":[72],"non-compliance,":[74,136,216,341,404],"5":[76,149],"different":[77],"ways":[78],"assess":[80,135],"those.":[81],"METHODS:":[82],"analysed":[84],"number":[86],"clinical,":[88],"analytical":[89],"ultrasound":[91,130],"data":[92,382],"relating":[93],"34":[95],"patients":[97,226,295],"(according":[98],"Wallace-ARA":[101],"diagnostic":[102],"criteria":[103],"1977":[106],"EULAR":[109],"recommendations":[110],"diagnosis":[113],"2006),":[114],"which":[115,153,383,398],"were":[116],"followed":[117],"in":[118,132],"specialized":[120],"rheumatology":[121],"consultation":[122],"as":[123,371],"part":[124],"an":[126,198,334],"ongoing":[127],"study":[128,332],"validation":[131],"gout.":[133],"To":[134],"we":[137,268],"compared":[138],"prevalence":[140],"each":[142],"one":[143],"these":[145],"outcomes":[150,168],"(2":[151],"related":[154,169],"\"non-compliance\":":[156],"self-report":[157,213,279,314],"non-adherence":[159],"therapy":[161],"missing":[163],"consultation,":[164],"3":[166,264],"other":[167,350],"\"non-response\":":[171],"flare(s),":[173],"final":[174,260,328],"serum":[175],"uric":[176],"acid":[177],"(sUA)":[178],"\u2265":[179],"6":[180],"mg/dL,":[181],"no":[183,318],"sonographic":[184,319],"improvement)":[185],"registered":[186],"during":[187,245],"1":[189,247],"year":[190,248],"follow-up":[192],"assessment.":[193],"RESULTS:":[194],"have":[196,251,269],"found":[197,354],"association":[199,274,335],"younger":[201],"age,":[202],"higher":[203,254,288,327],"body":[204],"mass":[205],"index,":[206],"previous":[207,215,281],"urate":[210],"lowering":[211],"drugs,":[212],"nephrolithiasis":[217],"hyperuricosuria":[219],"\"outcomes":[222,265],"non-compliance\".":[224],"These":[225,294],"tended":[227,296],"be":[229,298],"less":[230,299],"treated":[232,240,301,307],"NSAID":[234,379],"allopurinol,":[236],"more":[238,305],"corticosteroid":[242],"benzbromarone":[244],"follow-up.":[249],"They":[250],"also":[252,324],"presented":[253],"sUA.":[261,329],"Evaluating":[262],"non-response\",":[267],"noticed":[270],"tendency":[272],"long":[276],"duration,":[278],"non-compliance":[282,316,358],"(frequently":[283],"attributed":[284],"flare),":[287],"initial":[289],"sUA":[290],"kidney":[292,374],"failure.":[293],"NSAID,":[303],"allopurinol.":[309],"Gout":[310],"flare":[311],"correlated":[312,325],"improvement.":[320],"Sonographic":[321],"non":[322],"response":[323,364],"CONCLUSIONS:":[330],"This":[331],"shows":[333],"some":[337],"but":[342],"above":[343],"all,":[344],"unlike":[346],"majority":[348],"studies,":[351],"it":[352],"has":[353],"correlation":[356],"possible":[360],"causes":[361],"or":[365],"lower":[366],"treatment,":[369],"such":[370],"hyperuricosuria,":[372],"nephrolithiasis,":[373],"failure,":[375],"contraindication":[377],"treatment.":[380],"based":[385],"on":[386],"comprehensive":[388],"detailed":[390],"assessment,":[392],"might":[393,399],"point":[394],"out":[395],"hidden":[396],"elements,":[397],"go":[400],"beyond":[401],"visible":[403],"contributing":[405],"frequent":[408],"lack":[409],"control":[411],"disease.":[414]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":3},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}