{"id":"https://openalex.org/W765436581","doi":"https://doi.org/10.1371/journal.pone.0131907","title":"Plasmid-Encoded RepA Proteins Specifically Autorepress Individual repABC Operons in the Multipartite Rhizobium leguminosarum bv. trifolii Genome","display_name":"Plasmid-Encoded RepA Proteins Specifically Autorepress Individual repABC Operons in the Multipartite Rhizobium leguminosarum bv. trifolii Genome","publication_year":2015,"publication_date":"2015-07-06","ids":{"openalex":"https://openalex.org/W765436581","doi":"https://doi.org/10.1371/journal.pone.0131907","mag":"765436581","pmid":"https://pubmed.ncbi.nlm.nih.gov/26147968","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4492784"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pone.0131907","doi":"https://doi.org/10.1371/journal.pone.0131907","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0131907","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0131907&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0131907&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084553464","display_name":"Kamil \u017bebracki","orcid":"https://orcid.org/0000-0001-7250-4492","observed_orcids":["https://orcid.org/0000-0001-7250-4492"]},"institutions":[{"id":"https://openalex.org/I174183983","display_name":"Maria Curie-Sk\u0142odowska University","ror":"https://ror.org/015h0qg34","country_code":"PL","type":"education","lineage":["https://openalex.org/I174183983"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Kamil \u017bebracki","raw_affiliation_strings":["Department of Genetics and Microbiology, Institute of Microbiology and Biotechnology, Faculty of Biology and Biotechnology, Maria Curie-Sk\u0142odowska University, Lublin, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics and Microbiology, Institute of Microbiology and Biotechnology, Faculty of Biology and Biotechnology, Maria Curie-Sk\u0142odowska University, Lublin, Poland","institution_ids":["https://openalex.org/I174183983"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016483636","display_name":"Piotr Koper","orcid":"https://orcid.org/0000-0002-0386-3544","observed_orcids":["https://orcid.org/0000-0002-0386-3544"]},"institutions":[{"id":"https://openalex.org/I174183983","display_name":"Maria Curie-Sk\u0142odowska University","ror":"https://ror.org/015h0qg34","country_code":"PL","type":"education","lineage":["https://openalex.org/I174183983"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Piotr Koper","raw_affiliation_strings":["Department of Genetics and Microbiology, Institute of Microbiology and Biotechnology, Faculty of Biology and Biotechnology, Maria Curie-Sk\u0142odowska University, Lublin, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics and Microbiology, Institute of Microbiology and Biotechnology, Faculty of Biology and Biotechnology, Maria Curie-Sk\u0142odowska University, Lublin, Poland","institution_ids":["https://openalex.org/I174183983"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013249540","display_name":"Ma\u0142gorzata Marczak","orcid":"https://orcid.org/0000-0002-0230-103X","observed_orcids":["https://orcid.org/0000-0002-0230-103X"]},"institutions":[{"id":"https://openalex.org/I174183983","display_name":"Maria Curie-Sk\u0142odowska University","ror":"https://ror.org/015h0qg34","country_code":"PL","type":"education","lineage":["https://openalex.org/I174183983"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Ma\u0142gorzata Marczak","raw_affiliation_strings":["Department of Genetics and Microbiology, Institute of Microbiology and Biotechnology, Faculty of Biology and Biotechnology, Maria Curie-Sk\u0142odowska University, Lublin, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics and Microbiology, Institute of Microbiology and Biotechnology, Faculty of Biology and Biotechnology, Maria Curie-Sk\u0142odowska University, Lublin, Poland","institution_ids":["https://openalex.org/I174183983"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077206589","display_name":"Anna Skorupska","orcid":"https://orcid.org/0000-0002-1845-6685","observed_orcids":["https://orcid.org/0000-0002-1845-6685"]},"institutions":[{"id":"https://openalex.org/I174183983","display_name":"Maria Curie-Sk\u0142odowska University","ror":"https://ror.org/015h0qg34","country_code":"PL","type":"education","lineage":["https://openalex.org/I174183983"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Anna Skorupska","raw_affiliation_strings":["Department of Genetics and Microbiology, Institute of Microbiology and Biotechnology, Faculty of Biology and Biotechnology, Maria Curie-Sk\u0142odowska University, Lublin, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics and Microbiology, Institute of Microbiology and Biotechnology, Faculty of Biology and Biotechnology, Maria Curie-Sk\u0142odowska University, Lublin, Poland","institution_ids":["https://openalex.org/I174183983"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102002731","display_name":"Andrzej Mazur","orcid":"https://orcid.org/0000-0002-3503-7642","observed_orcids":["https://orcid.org/0000-0002-3503-7642"]},"institutions":[{"id":"https://openalex.org/I174183983","display_name":"Maria Curie-Sk\u0142odowska University","ror":"https://ror.org/015h0qg34","country_code":"PL","type":"education","lineage":["https://openalex.org/I174183983"]}],"countries":["PL"],"is_corresponding":true,"raw_author_name":"Andrzej Mazur","raw_affiliation_strings":["Department of Genetics and Microbiology, Institute of Microbiology and Biotechnology, Faculty of Biology and Biotechnology, Maria Curie-Sk\u0142odowska University, Lublin, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics and Microbiology, Institute of Microbiology and Biotechnology, Faculty of Biology and Biotechnology, Maria Curie-Sk\u0142odowska University, Lublin, Poland","institution_ids":["https://openalex.org/I174183983"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5102002731"],"corresponding_institution_ids":["https://openalex.org/I174183983"],"apc_list":{"value":2382,"currency":"USD","value_usd":2382},"apc_paid":{"value":2382,"currency":"USD","value_usd":2382},"fwci":0.8131,"has_fulltext":true,"cited_by_count":14,"citation_normalized_percentile":{"value":0.70168643,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"10","issue":"7","first_page":"e0131907","last_page":"e0131907"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11470","display_name":"Legume Nitrogen Fixing Symbiosis","score":0.009700000286102295,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rhizobium-leguminosarum-bv-trifolii","display_name":"Rhizobium leguminosarum bv. trifolii","score":0.9639999866485596},{"id":"https://openalex.org/keywords/repa","display_name":"RepA","score":0.6480000019073486},{"id":"https://openalex.org/keywords/repb","display_name":"RepB","score":0.9419999718666077},{"id":"https://openalex.org/keywords/plasmid-replication","display_name":"plasmid replication","score":0.7850000262260437},{"id":"https://openalex.org/keywords/plasmid-partitioning","display_name":"plasmid partitioning","score":0.8500000238418579},{"id":"https://openalex.org/keywords/transcriptional-regulation","display_name":"transcriptional regulation","score":0.8550000190734863},{"id":"https://openalex.org/keywords/multipartite-genome","display_name":"multipartite genome","score":0.9120000004768372},{"id":"https://openalex.org/keywords/plasmid-coexistence","display_name":"plasmid coexistence","score":0.6830000281333923}],"concepts":[{"id":"https://openalex.org/C22744801","wikidata":"https://www.wikidata.org/wiki/Q172778","display_name":"Plasmid","level":3,"score":0.8997093439102173},{"id":"https://openalex.org/C203075996","wikidata":"https://www.wikidata.org/wiki/Q139677","display_name":"Operon","level":4,"score":0.8364071846008301},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8269127607345581},{"id":"https://openalex.org/C18103114","wikidata":"https://www.wikidata.org/wiki/Q1720369","display_name":"Replicon","level":4,"score":0.74275803565979},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.7410085201263428},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.6793272495269775},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.6403450965881348},{"id":"https://openalex.org/C2776336279","wikidata":"https://www.wikidata.org/wiki/Q3934108","display_name":"Rhizobium leguminosarum","level":5,"score":0.5783612132072449},{"id":"https://openalex.org/C3742359","wikidata":"https://www.wikidata.org/wiki/Q4839988","display_name":"Bacterial genome size","level":4,"score":0.4241538941860199},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.14763891696929932},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.10232922434806824},{"id":"https://openalex.org/C2779856404","wikidata":"https://www.wikidata.org/wiki/Q2462359","display_name":"Rhizobiaceae","level":4,"score":0.08134835958480835},{"id":"https://openalex.org/C43144210","wikidata":"https://www.wikidata.org/wiki/Q121610","display_name":"Symbiosis","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000255","descriptor_name":"Adenosine Triphosphate","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D004261","descriptor_name":"DNA Replication","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004269","descriptor_name":"DNA, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009876","descriptor_name":"Operon","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D010957","descriptor_name":"Plasmids","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012093","descriptor_name":"Replicon","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015964","descriptor_name":"Gene Expression Regulation, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016680","descriptor_name":"Genome, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016961","descriptor_name":"Rhizobium leguminosarum","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016961","descriptor_name":"Rhizobium leguminosarum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1371/journal.pone.0131907","doi":"https://doi.org/10.1371/journal.pone.0131907","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0131907","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0131907&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3466951","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4492784","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:26147968","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26147968","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PloS one","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4492784","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4492784/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS One","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.779.8453","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.779.8453","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/fe/36/pone.0131907.PMC4492784.pdf","raw_type":"text"},{"id":"pmh:oai:doaj.org/article:e13f8dcb6457458fbbab916457375007","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/e13f8dcb6457458fbbab916457375007","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, Vol 10, Iss 7, p e0131907 (2015)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1371/journal.pone.0131907","doi":"https://doi.org/10.1371/journal.pone.0131907","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0131907","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0131907&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W765436581.pdf","grobid_xml":"https://content.openalex.org/works/W765436581.grobid-xml"},"referenced_works_count":53,"referenced_works":["https://openalex.org/W630352753","https://openalex.org/W1481914385","https://openalex.org/W1532814292","https://openalex.org/W1546783991","https://openalex.org/W1581591524","https://openalex.org/W1616014021","https://openalex.org/W1678533476","https://openalex.org/W1880436856","https://openalex.org/W1956881088","https://openalex.org/W1957001277","https://openalex.org/W1967691135","https://openalex.org/W1968196536","https://openalex.org/W1970877539","https://openalex.org/W1974119162","https://openalex.org/W1981333610","https://openalex.org/W1981488737","https://openalex.org/W1984731526","https://openalex.org/W1989964337","https://openalex.org/W1996958302","https://openalex.org/W2007857790","https://openalex.org/W2024041761","https://openalex.org/W2027117520","https://openalex.org/W2036917159","https://openalex.org/W2044531003","https://openalex.org/W2047670590","https://openalex.org/W2047792838","https://openalex.org/W2048451605","https://openalex.org/W2061406444","https://openalex.org/W2064102729","https://openalex.org/W2068904715","https://openalex.org/W2069830720","https://openalex.org/W2075793022","https://openalex.org/W2078508016","https://openalex.org/W2078651213","https://openalex.org/W2082248705","https://openalex.org/W2088780096","https://openalex.org/W2099649539","https://openalex.org/W2106939093","https://openalex.org/W2113096051","https://openalex.org/W2113197426","https://openalex.org/W2114829255","https://openalex.org/W2119507686","https://openalex.org/W2124605447","https://openalex.org/W2126301105","https://openalex.org/W2128564866","https://openalex.org/W2130554390","https://openalex.org/W2144634347","https://openalex.org/W2146706999","https://openalex.org/W2148788880","https://openalex.org/W2153187042","https://openalex.org/W2171720687","https://openalex.org/W2436738627","https://openalex.org/W2539537687"],"related_works":["https://openalex.org/W7097714661","https://openalex.org/W2475468054","https://openalex.org/W2027117520","https://openalex.org/W1616014021","https://openalex.org/W1999781102","https://openalex.org/W2048451605","https://openalex.org/W2113096051","https://openalex.org/W1957001277","https://openalex.org/W1996958302","https://openalex.org/W2007857790"],"abstract_inverted_index":{"Rhizobia":[0],"commonly":[1],"have":[2],"very":[3],"complex":[4,56,268],"genomes":[5],"with":[6,80,262],"a":[7,73,221],"chromosome":[8,74],"and":[9,22,29,48,75,108,144,173,237,248],"several":[10,260],"large":[11],"plasmids":[12,77,100,135,224],"that":[13,212],"possess":[14],"genes":[15,132],"belonging":[16],"to":[17,150,152,165,187,194,255],"the":[18,27,44,87,92,97,106,159,178,208,216,229,235,246,256,267],"repABC":[19,45,82,94,131,264],"family.":[20],"RepA":[21,107,143,147,186,190,251],"RepB":[23,109],"are":[24,51],"members":[25],"of":[26,32,58,64,72,89,91,96,105,126,133,161,180,185,201,210,223,226,239,250,259],"ParA":[28],"ParB":[30],"families":[31],"partitioning":[33,47],"proteins,":[34,252],"respectively,":[35],"whereas":[36,177],"RepC":[37],"is":[38],"crucial":[39],"for":[40],"plasmid":[41],"replication.":[42],"In":[43,84],"replicons,":[46,228],"replication":[49],"functions":[50],"transcriptionally":[52],"linked":[53],"resulting":[54],"in":[55,116,124,158,196,266],"regulation":[57,88,238],"rep":[59,128,241],"gene":[60],"expression.":[61],"The":[62,103,189],"genome":[63],"R.":[65],"leguminosarum":[66],"bv.":[67],"trifolii":[68],"TA1":[69],"(RtTA1)":[70],"consists":[71],"four":[76,98],"(pRleTA1a-d),":[78],"equipped":[79],"functional":[81],"genes.":[83],"this":[85,117],"work,":[86],"transcription":[90],"individual":[93,134,227],"cassettes":[95,265],"RtTA1":[99,130],"was":[101,119],"studied.":[102],"involvement":[104],"as":[110,112,243,245],"well":[111,244],"parS-like":[113],"centromere":[114],"sites":[115],"process":[118],"depicted,":[120],"demonstrating":[121],"some":[122],"dissimilarity":[123],"expression":[125],"respective":[127],"regions.":[129],"formed":[136,199],"operons,":[137],"which":[138,253],"were":[139,148,192,213],"negatively":[140],"regulated":[141],"by":[142],"RepB.":[145],"Individual":[146],"able":[149,193],"bind":[151],"DNA":[153],"without":[154],"added":[155],"nucleotides,":[156],"but":[157],"presence":[160],"ADP,":[162,204],"bound":[163],"specifically":[164],"their":[166],"own":[167],"operator":[168],"sequences":[169],"containing":[170],"imperfect":[171],"palindromes,":[172],"caused":[174],"operon":[175],"autorepression,":[176],"addition":[179],"ATP":[181,202,206],"stimulated":[182],"non-specific":[183],"binding":[184],"DNA.":[188],"proteins":[191],"dimerize/oligomerize:":[195],"general":[197],"dimers":[198],"independently":[200],"or":[203],"although":[205],"diminished":[207],"concentration":[209],"oligomers":[211],"produced.":[214],"By":[215],"comprehensive":[217],"approach":[218],"focusing":[219],"on":[220],"set":[222],"instead":[225],"work":[230],"highlighted":[231],"subtle":[232],"differences":[233],"between":[234],"organization":[236],"particular":[240],"operons":[242],"structures":[247],"specificity":[249],"contribute":[254],"fine-tuned":[257],"coexistence":[258],"replicons":[261],"similar":[263],"bacterial":[269],"genome.":[270]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}
