{"id":"https://openalex.org/W7634902","doi":null,"title":"Missing expression of pRb2/p130 in human retinoblastomas is associated with reduced apoptosis and lesser differentiation.","display_name":"Missing expression of pRb2/p130 in human retinoblastomas is associated with reduced apoptosis and lesser differentiation.","publication_year":2002,"publication_date":"2002-12-01","ids":{"openalex":"https://openalex.org/W7634902","mag":"7634902","pmid":"https://pubmed.ncbi.nlm.nih.gov/12454024"},"language":"en","primary_location":{"id":"pmid:12454024","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12454024","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Investigative ophthalmology & visual science","raw_type":"Comparative Study"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045559679","display_name":"Cristiana Bellan","orcid":"https://orcid.org/0000-0001-6119-9007","observed_orcids":["https://orcid.org/0000-0001-6119-9007"]},"institutions":[{"id":"https://openalex.org/I102064193","display_name":"University of Siena","ror":"https://ror.org/01tevnk56","country_code":"IT","type":"education","lineage":["https://openalex.org/I102064193"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Cristiana Bellan","raw_affiliation_strings":["Institute of Pathologic Anatomy and Histology, University of Siena, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Pathologic Anatomy and Histology, University of Siena, Italy","institution_ids":["https://openalex.org/I102064193"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103467833","display_name":"Giulia De Falco","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Giulia De Falco","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049657376","display_name":"Gian Marco Tosi","orcid":"https://orcid.org/0000-0001-9289-1717","observed_orcids":["https://orcid.org/0000-0001-9289-1717"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gian Marco Tosi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038020866","display_name":"Stefano Lazzi","orcid":"https://orcid.org/0000-0002-2218-3771","observed_orcids":["https://orcid.org/0000-0002-2218-3771"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stefano Lazzi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036132138","display_name":"Filomena Ferrari","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Filomena Ferrari","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027542766","display_name":"Giovanna Morbini","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Giovanna Morbini","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089202451","display_name":"Sabrina Bartolommei","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sabrina Bartolomei","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059267532","display_name":"Paolo Toti","orcid":"https://orcid.org/0000-0002-1214-5886","observed_orcids":["https://orcid.org/0000-0002-1214-5886"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Paolo Toti","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063354486","display_name":"Paola Mangiavacchi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Paola Mangiavacchi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014725590","display_name":"Gabriele Cevenini","orcid":"https://orcid.org/0000-0002-7212-573X","observed_orcids":["https://orcid.org/0000-0002-7212-573X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gabriele Cevenini","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072639710","display_name":"Carmela Trimarchi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Carmela Trimarchi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084895786","display_name":"Caterina Cinti","orcid":"https://orcid.org/0000-0001-8049-0369","observed_orcids":["https://orcid.org/0000-0001-8049-0369"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Caterina Cinti","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024798356","display_name":"Antonio Giordano","orcid":"https://orcid.org/0000-0002-5959-016X","observed_orcids":["https://orcid.org/0000-0002-5959-016X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Antonio Giordano","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048326208","display_name":"Lorenzo Leoncini","orcid":"https://orcid.org/0000-0002-7457-300X","observed_orcids":["https://orcid.org/0000-0002-7457-300X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lorenzo Leoncini","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111803662","display_name":"Piero Tosi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Piero Tosi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5091094049","display_name":"Hans Cottier","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hans Cottier","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.0131,"has_fulltext":false,"cited_by_count":29,"citation_normalized_percentile":{"value":0.84846262,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"43","issue":"12","first_page":"3602","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11328","display_name":"Ocular Oncology and Treatments","score":0.9545999765396118,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11328","display_name":"Ocular Oncology and Treatments","score":0.9545999765396118,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways","score":0.02250000089406967,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.019099999219179153,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prb2-p130","display_name":"pRb2/p130","score":0.9359999895095825},{"id":"https://openalex.org/keywords/retinoblastoma","display_name":"retinoblastoma","score":0.9729999899864197},{"id":"https://openalex.org/keywords/retinoblastoma-gene","display_name":"retinoblastoma gene","score":0.8159999847412109},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.9039999842643738},{"id":"https://openalex.org/keywords/tumor-differentiation","display_name":"tumor differentiation","score":0.7490000128746033},{"id":"https://openalex.org/keywords/apoptotic-index","display_name":"apoptosis index","score":0.7210000157356262},{"id":"https://openalex.org/keywords/mitotic-index","display_name":"mitotic index","score":0.9779999852180481},{"id":"https://openalex.org/keywords/tumor-suppressor-genes","display_name":"tumor suppressor","score":0.7689999938011169},{"id":"https://openalex.org/keywords/saos-2-cells","display_name":"Saos-2 cells","score":0.8989999890327454}],"concepts":[{"id":"https://openalex.org/C2776577112","wikidata":"https://www.wikidata.org/wiki/Q500695","display_name":"Retinoblastoma","level":3,"score":0.8019876480102539},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.7303035855293274},{"id":"https://openalex.org/C2776062698","wikidata":"https://www.wikidata.org/wiki/Q21111463","display_name":"Retinoblastoma protein","level":4,"score":0.5754400491714478},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5509426593780518},{"id":"https://openalex.org/C553184892","wikidata":"https://www.wikidata.org/wiki/Q1141429","display_name":"Flow cytometry","level":2,"score":0.49210280179977417},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.4700939357280731},{"id":"https://openalex.org/C2778264664","wikidata":"https://www.wikidata.org/wiki/Q422445","display_name":"Tumor suppressor gene","level":4,"score":0.45259523391723633},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4385968744754791},{"id":"https://openalex.org/C54009773","wikidata":"https://www.wikidata.org/wiki/Q1429031","display_name":"Transfection","level":3,"score":0.4340718984603882},{"id":"https://openalex.org/C66640590","wikidata":"https://www.wikidata.org/wiki/Q4296711","display_name":"Mitotic index","level":3,"score":0.42915087938308716},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.38633355498313904},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.37689408659935},{"id":"https://openalex.org/C93304396","wikidata":"https://www.wikidata.org/wiki/Q14763008","display_name":"Mitosis","level":2,"score":0.33281761407852173},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3068760633468628},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.2661299705505371},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D002452","descriptor_name":"Cell Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005434","descriptor_name":"Flow Cytometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007124","descriptor_name":"Immunoenzyme Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008940","descriptor_name":"Mitotic Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010750","descriptor_name":"Phosphoproteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010750","descriptor_name":"Phosphoproteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012160","descriptor_name":"Retina","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012175","descriptor_name":"Retinoblastoma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012175","descriptor_name":"Retinoblastoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014162","descriptor_name":"Transfection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014407","descriptor_name":"Tumor Cells, Cultured","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014407","descriptor_name":"Tumor Cells, Cultured","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D015153","descriptor_name":"Blotting, Western","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016160","descriptor_name":"Retinoblastoma Protein","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016160","descriptor_name":"Retinoblastoma Protein","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019572","descriptor_name":"Retinal Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019572","descriptor_name":"Retinal Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D050717","descriptor_name":"Retinoblastoma-Like Protein p130","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:12454024","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12454024","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Investigative ophthalmology & visual science","raw_type":"Comparative Study"},{"id":"pmh:oai:usiena-air.unisi.it:11365/28950","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11365/28950","pdf_url":null,"source":{"id":"https://openalex.org/S4377196319","display_name":"Use Siena air (University of Siena)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I102064193","host_organization_name":"University of Siena","host_organization_lineage":["https://openalex.org/I102064193"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"mag:7634902","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12454024","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":46,"referenced_works":["https://openalex.org/W55249762","https://openalex.org/W91495214","https://openalex.org/W148167943","https://openalex.org/W657688179","https://openalex.org/W1214162112","https://openalex.org/W1519100182","https://openalex.org/W1519668503","https://openalex.org/W1586129343","https://openalex.org/W1594726480","https://openalex.org/W1666203926","https://openalex.org/W1867389122","https://openalex.org/W1907107591","https://openalex.org/W1973138645","https://openalex.org/W1992387677","https://openalex.org/W1993148317","https://openalex.org/W1993790910","https://openalex.org/W1997093143","https://openalex.org/W1999523595","https://openalex.org/W2022329296","https://openalex.org/W2025215722","https://openalex.org/W2026106245","https://openalex.org/W2027594588","https://openalex.org/W2039212054","https://openalex.org/W2041825273","https://openalex.org/W2063367127","https://openalex.org/W2070143003","https://openalex.org/W2071307438","https://openalex.org/W2072320859","https://openalex.org/W2073960683","https://openalex.org/W2078764481","https://openalex.org/W2087390195","https://openalex.org/W2099566069","https://openalex.org/W2100924809","https://openalex.org/W2142545082","https://openalex.org/W2151812144","https://openalex.org/W2168910105","https://openalex.org/W2171081413","https://openalex.org/W2260360194","https://openalex.org/W2261531865","https://openalex.org/W2317898068","https://openalex.org/W2321856961","https://openalex.org/W2326298037","https://openalex.org/W2394936623","https://openalex.org/W2410080476","https://openalex.org/W2412747890","https://openalex.org/W3153391969"],"related_works":["https://openalex.org/W2129228502","https://openalex.org/W2468165450","https://openalex.org/W2094781365","https://openalex.org/W2049783958","https://openalex.org/W6990709863","https://openalex.org/W4244139050","https://openalex.org/W2404198899","https://openalex.org/W2087390195","https://openalex.org/W2523123195","https://openalex.org/W1978434551"],"abstract_inverted_index":{"PURPOSE:":[0],"Although":[1],"the":[2,20,54,69,78,82,98,102,109,114,166],"retinoblastoma":[3],"gene":[4,14,76],"(RB/p105)":[5],"has":[6,26,36],"been":[7,29,37],"intensely":[8],"investigated":[9],"as":[10],"a":[11,72,127,145,160],"prototype":[12],"suppressor":[13],"in":[15,42,45,58,77,186,198],"humans,":[16],"mutational":[17],"data":[18],"on":[19,53,144],"Rb":[21,83],"family":[22,84],"member":[23],"pRb2/p130":[24,57],"(p130)":[25],"only":[27,48],"recently":[28],"reported.":[30],"A":[31],"protective":[32],"role":[33,55,73,197],"against":[34],"apoptosis":[35,185],"suggested":[38],"for":[39],"pRb/p105,":[40],"both":[41],"vitro":[43],"and":[44,101,113,189],"vivo.":[46],"However,":[47],"limited":[49],"information":[50],"is":[51,178],"available":[52],"of":[56,63,71,74,97,163,176,184,194],"controlling":[59],"apoptosis.":[60],"The":[61,119,156],"purpose":[62],"this":[64,75,195],"study":[65],"was":[66,138,151],"to":[67],"determine":[68],"extent":[70],"neoplasms":[79],"that":[80,121,133,150,174],"give":[81,172,190],"its":[85],"name.":[86],"METHODS:":[87],"Forty-two":[88],"human":[89,146,187],"retinoblastomas":[90,120,188],"were":[91],"retrospectively":[92],"examined":[93],"by":[94,141],"immunohistochemical":[95],"labeling":[96],"Rb-related":[99],"proteins":[100],"results":[103],"compared":[104],"with":[105,154,181],"cellular":[106,199],"kinetic":[107],"characteristics:":[108],"apoptotic":[110],"index":[111,116],"(AI)":[112],"mitotic":[115],"(MI).":[117],"RESULTS:":[118],"did":[122],"not":[123],"express":[124],"p130":[125,177],"showed":[126],"significantly":[128],"lower":[129],"AI":[130],"than":[131,165],"those":[132],"expressed":[134],"p130.":[135],"This":[136],"result":[137],"also":[139],"supported":[140],"flow":[142],"cytometry":[143],"Saos-2":[147],"cell":[148],"line":[149],"transiently":[152],"transfected":[153],"RB2/p130.":[155],"p130(-)":[157],"tumors":[158],"displayed":[159],"lesser":[161],"degree":[162],"differentiation":[164],"p130(+)":[167],"ones.":[168],"CONCLUSIONS:":[169],"These":[170],"observations":[171],"evidence":[173],"expression":[175],"inversely":[179],"correlated":[180],"higher":[182],"rates":[183],"an":[191],"additional":[192],"example":[193],"regulator's":[196],"differentiation.":[200]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}