{"id":"https://openalex.org/W759808786","doi":null,"title":"Bioactive fatty acids as dietary supplements for farmed fish : effects on growth performance, lipid metabolism, gene expression and immune parameters","display_name":"Bioactive fatty acids as dietary supplements for farmed fish : effects on growth performance, lipid metabolism, gene expression and immune parameters","publication_year":2007,"publication_date":"2007-10-01","ids":{"openalex":"https://openalex.org/W759808786","mag":"759808786"},"language":"en","primary_location":{"id":"pmh:oai:dspace.stir.ac.uk:1893/389","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/1893/389","pdf_url":null,"source":{"id":"https://openalex.org/S4306400268","display_name":"Stirling Online Research Repository (University of Stirling)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I12093191","host_organization_name":"University of Stirling","host_organization_lineage":["https://openalex.org/I12093191"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis or Dissertation"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046865452","display_name":"Sean R. Kennedy","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Sean R. Kennedy","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5046865452"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10450","display_name":"Aquaculture Nutrition and Growth","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1104","display_name":"Aquatic Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10450","display_name":"Aquaculture Nutrition and Growth","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1104","display_name":"Aquatic Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10387","display_name":"Fatty Acid Research and Health","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10506","display_name":"Aquaculture disease management and microbiota","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bioactive-fatty-acids","display_name":"bioactive fatty acids","score":0.8939999938011169},{"id":"https://openalex.org/keywords/conjugated-linoleic-acid","display_name":"conjugated linoleic acid","score":0.9879999756813049},{"id":"https://openalex.org/keywords/tetradecylthioacetic-acid","display_name":"tetradecylthioacetic acid","score":0.9909999966621399},{"id":"https://openalex.org/keywords/fish-feed-supplementation","display_name":"fish feed supplementation","score":0.5339999794960022},{"id":"https://openalex.org/keywords/atlantic-salmon","display_name":"Atlantic salmon","score":0.671999990940094},{"id":"https://openalex.org/keywords/atlantic-cod","display_name":"Gadus morhua","score":0.9980000257492065},{"id":"https://openalex.org/keywords/rainbow-trout","display_name":"rainbow trout","score":0.9990000128746033},{"id":"https://openalex.org/keywords/fat-deposition","display_name":"fat deposition","score":0.8519999980926514},{"id":"https://openalex.org/keywords/n-3-highly-unsaturated-fatty-acids","display_name":"n-3 highly unsaturated fatty acids","score":0.9399999976158142},{"id":"https://openalex.org/keywords/fatty-acid-oxidation","display_name":"fatty acid oxidation","score":0.875},{"id":"https://openalex.org/keywords/lipid-metabolism","display_name":"lipid metabolism","score":0.9139999747276306},{"id":"https://openalex.org/keywords/gene-expression","display_name":"gene expression","score":0.6499999761581421},{"id":"https://openalex.org/keywords/immune-response","display_name":"immune response","score":0.5429999828338623},{"id":"https://openalex.org/keywords/fish-flesh-quality","display_name":"fish meat quality","score":0.367000013589859},{"id":"https://openalex.org/keywords/aquaculture-nutrition","display_name":"aquaculture nutrition","score":0.621999979019165}],"concepts":[{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6648795008659363},{"id":"https://openalex.org/C4733338","wikidata":"https://www.wikidata.org/wiki/Q2792936","display_name":"Lipid metabolism","level":2,"score":0.6176506876945496},{"id":"https://openalex.org/C2909208804","wikidata":"https://www.wikidata.org/wiki/Q127282","display_name":"Fish <Actinopterygii>","level":2,"score":0.5834008455276489},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.541865348815918},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.5200937986373901},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.4763091802597046},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.4566591680049896},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.40861618518829346},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.40046149492263794},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.3716413974761963},{"id":"https://openalex.org/C505870484","wikidata":"https://www.wikidata.org/wiki/Q180538","display_name":"Fishery","level":1,"score":0.27682816982269287},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.20281869173049927}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:dspace.stir.ac.uk:1893/389","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/1893/389","pdf_url":null,"source":{"id":"https://openalex.org/S4306400268","display_name":"Stirling Online Research Repository (University of Stirling)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I12093191","host_organization_name":"University of Stirling","host_organization_lineage":["https://openalex.org/I12093191"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis or Dissertation"},{"id":"mag:759808786","doi":null,"is_oa":false,"landing_page_url":"https://dspace.stir.ac.uk/bitstream/1893/389/1/kennedy-farmed-fish-thesis.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/2","score":0.9208999872207642,"display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":230,"referenced_works":["https://openalex.org/W5739282","https://openalex.org/W19575447","https://openalex.org/W48838759","https://openalex.org/W67899302","https://openalex.org/W153267565","https://openalex.org/W161100052","https://openalex.org/W229667467","https://openalex.org/W323187656","https://openalex.org/W336828113","https://openalex.org/W945114449","https://openalex.org/W1486425313","https://openalex.org/W1499242142","https://openalex.org/W1515253497","https://openalex.org/W1531583469","https://openalex.org/W1540116808","https://openalex.org/W1580603612","https://openalex.org/W1775749144","https://openalex.org/W1870633384","https://openalex.org/W1875703966","https://openalex.org/W1893518434","https://openalex.org/W1897299115","https://openalex.org/W1900102735","https://openalex.org/W1907219612","https://openalex.org/W1911193726","https://openalex.org/W1920532929","https://openalex.org/W1930140290","https://openalex.org/W1931639373","https://openalex.org/W1934166066","https://openalex.org/W1936171856","https://openalex.org/W1942808992","https://openalex.org/W1944959052","https://openalex.org/W1945187277","https://openalex.org/W1957144354","https://openalex.org/W1957299618","https://openalex.org/W1961468023","https://openalex.org/W1963535029","https://openalex.org/W1965398123","https://openalex.org/W1966404654","https://openalex.org/W1966860456","https://openalex.org/W1967338219","https://openalex.org/W1967952117","https://openalex.org/W1968659767","https://openalex.org/W1969608786","https://openalex.org/W1971399698","https://openalex.org/W1972255781","https://openalex.org/W1973376183","https://openalex.org/W1973895626","https://openalex.org/W1975267685","https://openalex.org/W1975816358","https://openalex.org/W1976426345","https://openalex.org/W1977247177","https://openalex.org/W1977419712","https://openalex.org/W1977657113","https://openalex.org/W1977857319","https://openalex.org/W1980159672","https://openalex.org/W1981497491","https://openalex.org/W1982027543","https://openalex.org/W1983020048","https://openalex.org/W1985538400","https://openalex.org/W1985918003","https://openalex.org/W1986111942","https://openalex.org/W1990365946","https://openalex.org/W1991028670","https://openalex.org/W1991616044","https://openalex.org/W1992209802","https://openalex.org/W1992706244","https://openalex.org/W1993335180","https://openalex.org/W1995756653","https://openalex.org/W2000136948","https://openalex.org/W2001806761","https://openalex.org/W2003398104","https://openalex.org/W2004583346","https://openalex.org/W2004927367","https://openalex.org/W2005672961","https://openalex.org/W2005784265","https://openalex.org/W2005825861","https://openalex.org/W2006202375","https://openalex.org/W2007072673","https://openalex.org/W2009655337","https://openalex.org/W2010708771","https://openalex.org/W2011825014","https://openalex.org/W2011829422","https://openalex.org/W2012063330","https://openalex.org/W2013344341","https://openalex.org/W2013397016","https://openalex.org/W2014045619","https://openalex.org/W2014078068","https://openalex.org/W2015504247","https://openalex.org/W2017328769","https://openalex.org/W2020767358","https://openalex.org/W2021562707","https://openalex.org/W2022942455","https://openalex.org/W2023567293","https://openalex.org/W2023983741","https://openalex.org/W2023997176","https://openalex.org/W2024468043","https://openalex.org/W2024827610","https://openalex.org/W2025583633","https://openalex.org/W2026032512","https://openalex.org/W2029598860","https://openalex.org/W2033106945","https://openalex.org/W2033805912","https://openalex.org/W2034052843","https://openalex.org/W2034316241","https://openalex.org/W2036154351","https://openalex.org/W2036169454","https://openalex.org/W2037127368","https://openalex.org/W2037360988","https://openalex.org/W2037481248","https://openalex.org/W2039111312","https://openalex.org/W2039488756","https://openalex.org/W2041380356","https://openalex.org/W2046863455","https://openalex.org/W2047132457","https://openalex.org/W2047264892","https://openalex.org/W2049133024","https://openalex.org/W2052302005","https://openalex.org/W2054023216","https://openalex.org/W2056935575","https://openalex.org/W2057968950","https://openalex.org/W2058240826","https://openalex.org/W2059479765","https://openalex.org/W2060520494","https://openalex.org/W2061015693","https://openalex.org/W2061496018","https://openalex.org/W2064730250","https://openalex.org/W2065636143","https://openalex.org/W2069348023","https://openalex.org/W2069856924","https://openalex.org/W2069954801","https://openalex.org/W2069992798","https://openalex.org/W2071187424","https://openalex.org/W2071764061","https://openalex.org/W2072330362","https://openalex.org/W2073048480","https://openalex.org/W2073431059","https://openalex.org/W2074024807","https://openalex.org/W2075183690","https://openalex.org/W2075915084","https://openalex.org/W2075931939","https://openalex.org/W2076789020","https://openalex.org/W2077043860","https://openalex.org/W2077137290","https://openalex.org/W2077207487","https://openalex.org/W2077926859","https://openalex.org/W2078643477","https://openalex.org/W2079599621","https://openalex.org/W2080074211","https://openalex.org/W2084434190","https://openalex.org/W2085011127","https://openalex.org/W2085087194","https://openalex.org/W2085495366","https://openalex.org/W2085560341","https://openalex.org/W2085589392","https://openalex.org/W2085974388","https://openalex.org/W2086840079","https://openalex.org/W2087760340","https://openalex.org/W2089461670","https://openalex.org/W2089919345","https://openalex.org/W2090644435","https://openalex.org/W2093844912","https://openalex.org/W2094744658","https://openalex.org/W2094962699","https://openalex.org/W2096043242","https://openalex.org/W2096956729","https://openalex.org/W2097294719","https://openalex.org/W2097722818","https://openalex.org/W2098874069","https://openalex.org/W2098915204","https://openalex.org/W2099249565","https://openalex.org/W2099755554","https://openalex.org/W2099759738","https://openalex.org/W2102318366","https://openalex.org/W2105140628","https://openalex.org/W2106592114","https://openalex.org/W2107245673","https://openalex.org/W2107436397","https://openalex.org/W2108616671","https://openalex.org/W2109190268","https://openalex.org/W2114364424","https://openalex.org/W2115920467","https://openalex.org/W2122974119","https://openalex.org/W2123418653","https://openalex.org/W2124246813","https://openalex.org/W2127799220","https://openalex.org/W2128454130","https://openalex.org/W2129153850","https://openalex.org/W2130663547","https://openalex.org/W2130755410","https://openalex.org/W2138299029","https://openalex.org/W2140994792","https://openalex.org/W2141423074","https://openalex.org/W2141486452","https://openalex.org/W2145820796","https://openalex.org/W2146999598","https://openalex.org/W2151229036","https://openalex.org/W2151760267","https://openalex.org/W2152088120","https://openalex.org/W2152247708","https://openalex.org/W2155709556","https://openalex.org/W2156167969","https://openalex.org/W2159567888","https://openalex.org/W2162250244","https://openalex.org/W2162283322","https://openalex.org/W2162645513","https://openalex.org/W2162885005","https://openalex.org/W2163056559","https://openalex.org/W2164220490","https://openalex.org/W2166080936","https://openalex.org/W2166869605","https://openalex.org/W2168526937","https://openalex.org/W2168906153","https://openalex.org/W2169752183","https://openalex.org/W2170155462","https://openalex.org/W2174878083","https://openalex.org/W2181442266","https://openalex.org/W2183377323","https://openalex.org/W2188802227","https://openalex.org/W2266168904","https://openalex.org/W2273570018","https://openalex.org/W2312751191","https://openalex.org/W2338606633","https://openalex.org/W2402828275","https://openalex.org/W2405102269","https://openalex.org/W2411131350","https://openalex.org/W2493157377","https://openalex.org/W2506796951","https://openalex.org/W2790364509","https://openalex.org/W3023891775","https://openalex.org/W4243470545"],"related_works":["https://openalex.org/W2011825014","https://openalex.org/W2087760340","https://openalex.org/W1990299414","https://openalex.org/W2075805186","https://openalex.org/W2036802034","https://openalex.org/W2003398104","https://openalex.org/W1926816795","https://openalex.org/W2034052843","https://openalex.org/W2008013898","https://openalex.org/W2073431059"],"abstract_inverted_index":{"Current":[0],"feed":[1],"formulations":[2],"within":[3],"the":[4,38,55,73,88,107,125,151,185,212,246,266,289,360,376,404,413,424,455,459],"aquaculture":[5],"industry":[6],"have":[7,263],"tended":[8],"to":[9,63,87,149,224,244,375,400,403,454],"rely":[10],"on":[11,83,93,218,300,303,320,386,415,439],"high":[12,39,60,132],"dietary":[13,250,445,462],"lipid":[14,40,61,228],"thus":[15,362],"offsetting":[16],"relatively":[17],"expensive":[18],"protein":[19,28],"as":[20,114,193,305],"a":[21,67,306,316,364,381,392],"source":[22],"of":[23,34,58,69,106,128,144,170,187,214,239,249,260,288,308,318,326,340,383,391,394,406,458,461],"energy.":[24],"In":[25],"this":[26,145,240,261,450],"\\nway,":[27],"can":[29,42,80,372],"be":[30,225,357,373,401],"\u2018spared\u2019":[31],"for":[32],"synthesis":[33],"new":[35],"tissue":[36],"and":[37,47,75,119,163,175,203,216,220,230,252,333,337,354,388,396,418,464],"content":[41],"also":[43,210,338,380,431],"fulfil":[44],"both":[45,352],"fish":[46,65,131,190,290,304],"consumer":[48],"essential":[49],"fatty":[50,111,165,173,180,231,321,370,407],"acid":[51,117,121,166,181,232,322,408],"(EFA)":[52],"requirements.":[53],"However,":[54,91,313,412],"main":[56],"disadvantage":[57],"feeding":[59,129],"levels":[62,183,302,344],"farmed":[64,130,467],"is":[66,101],"surplus":[68],"fat":[70,133,137,161,301],"deposition":[71,138,162],"in":[72,96,139,184,227,234,255,276,286,331,335,345,410,466],"flesh":[74,186,361],"other":[76,97],"important":[77,189],"tissues,":[78],"which":[79,367],"detrimentally":[81],"impact":[82,248,422],"quality":[84],"characteristics":[85],"central":[86],"human":[89],"consumer.":[90,377],"based":[92],"previous":[94],"work":[95,147,242,430],"animal":[98],"models,":[99],"it":[100,348],"entirely":[102],"feasible":[103],"that":[104,153,265,351,433],"supplementation":[105,285,443],"diet":[108],"with":[109,444],"bioactive":[110,172,369],"acids":[112,371],"such":[113,192],"conjugated":[115],"linoleic":[116],"(CLA)":[118],"tetradecylthioacetic":[120],"(TTA)":[122],"may":[123],"mitigate":[124],"deleterious":[126],"effects":[127,299,319,385,414,438],"diets":[134],"by":[135],"reducing":[136],"particular.":[140,235,411],"\\nThe":[141,258],"general":[142],"objective":[143],"research":[146,241,429],"was":[148,243,268,273,349],"test":[150],"hypothesis":[152,267],"CLA":[154,215,251,282,311,355,446,463],"and/or":[155],"TTA":[156,217,253,284,309,353,465],"could":[157,356],"augment":[158],"growth,":[159],"reduce":[160],"enhance":[164],"composition":[167],"via":[168],"incorporation":[169],"these":[171,256,368],"acids,":[174],"increase":[176],"n-3":[177,342],"highly":[178],"unsaturated":[179],"(HUFA)":[182],"commercially":[188],"species":[191,291],"Atlantic":[194,198],"salmon":[195],"(Salmo":[196],"salar),":[197],"cod":[199,332],"(Gadus":[200],"morhua":[201],"L.)":[202],"rainbow":[204],"trout":[205,334],"(Oncorhynchus":[206],"mykiss).":[207],"This":[208],"project":[209,262],"considered":[211],"influence":[213,460],"enzymes":[219,395],"transcription":[221,397,417],"factors":[222,398],"thought":[223,399],"pivotal":[226],"metabolism":[229,323],"oxidation":[233,409],"A":[236],"subsidiary":[237],"aim":[238],"investigate":[245],"immunological":[247],"administration":[254],"fish.":[257,468],"results":[259],"revealed":[264],"only":[269],"partly":[270],"proved.":[271],"There":[272,378],"no":[274,436],"effect":[275],"growth":[277],"or":[278,283,310,447],"biometry":[279],"after":[280,442],"either":[281],"any":[287],"investigated.":[292],"Additionally,":[293],"there":[294,314,434],"were":[295,315,379,435],"few":[296],"physiologically":[297],"significant":[298],"result":[307],"administration.":[312],"number":[317,382,393],"including":[324],"inhibition":[325],"steroyl":[327],"coenzyme":[328],"desaturase":[329],"(SCD)":[330],"particular":[336],"enhancement":[339],"hepatic":[341],"HUFA":[343],"trout.":[346],"Importantly,":[347],"determined":[350],"incorporated":[358],"into":[359],"providing":[363],"vehicle":[365],"through":[366],"delivered":[374],"beneficial":[384],"activity":[387],"gene":[389,416],"expression":[390],"fundamental":[402],"modulation":[405],"biochemistry":[419],"had":[420],"little":[421],"at":[423],"whole":[425],"body":[426],"level.":[427],"\\nThis":[428],"showed":[432],"detrimental":[437],"immune":[440],"status":[441],"TTA.":[448],"Conclusively,":[449],"thesis":[451],"has":[452],"contributed":[453],"overall":[456],"understanding":[457]},"counts_by_year":[{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
