{"id":"https://openalex.org/W75971980","doi":"https://doi.org/10.1007/978-3-540-73924-1_11","title":"Single-Molecule Microscopy and Force Spectroscopy of Membrane Proteins","display_name":"Single-Molecule Microscopy and Force Spectroscopy of Membrane Proteins","publication_year":2007,"publication_date":"2007-12-06","ids":{"openalex":"https://openalex.org/W75971980","doi":"https://doi.org/10.1007/978-3-540-73924-1_11","mag":"75971980"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-540-73924-1_11","doi":"https://doi.org/10.1007/978-3-540-73924-1_11","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-540-73924-1_11","pdf_url":null,"source":{"id":"https://openalex.org/S4210169908","display_name":"Springer series in biophysics","issn_l":"0932-2353","issn":["0932-2353","1868-2561"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Springer Series in Biophysics","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W1540426283","display_name":"Single Molecules and Nanotechnology"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052940235","display_name":"Andreas H. Engel","orcid":"https://orcid.org/0000-0002-0118-8733","observed_orcids":["https://orcid.org/0000-0002-0118-8733"]},"institutions":[{"id":"https://openalex.org/I1850255","display_name":"University of Basel","ror":"https://ror.org/02s6k3f65","country_code":"CH","type":"education","lineage":["https://openalex.org/I1850255"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Andreas Engel","raw_affiliation_strings":["M.E. M\u00fcller Institute for Structural Biology, Biozentrum, University of Basel, Basel, Switzerland","M.E. M\u00fcller Institute for Structural Biology, Biozentrum University of Basel, Basel, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"M.E. M\u00fcller Institute for Structural Biology, Biozentrum, University of Basel, Basel, Switzerland","institution_ids":["https://openalex.org/I1850255"]},{"raw_affiliation_string":"M.E. M\u00fcller Institute for Structural Biology, Biozentrum University of Basel, Basel, Switzerland","institution_ids":["https://openalex.org/I1850255"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053338933","display_name":"Harald Janovjak","orcid":"https://orcid.org/0000-0002-8023-9315","observed_orcids":["https://orcid.org/0000-0002-8023-9315"]},"institutions":[{"id":"https://openalex.org/I4405272450","display_name":"Biotechnologisches Zentrum","ror":"https://ror.org/046b28292","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4405272450","https://openalex.org/I4405279746","https://openalex.org/I78650965"]},{"id":"https://openalex.org/I78650965","display_name":"Technische Universit\u00e4t Dresden","ror":"https://ror.org/042aqky30","country_code":"DE","type":"education","lineage":["https://openalex.org/I78650965"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Harald Janovjak","raw_affiliation_strings":["Center of Biotechnology, University of Technology, Dresden, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Biotechnology, University of Technology, Dresden, Germany","institution_ids":["https://openalex.org/I4405272450","https://openalex.org/I78650965"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021120268","display_name":"Dimitrios Fotiadis","orcid":"https://orcid.org/0000-0001-9682-7931","observed_orcids":["https://orcid.org/0000-0001-9682-7931"]},"institutions":[{"id":"https://openalex.org/I1850255","display_name":"University of Basel","ror":"https://ror.org/02s6k3f65","country_code":"CH","type":"education","lineage":["https://openalex.org/I1850255"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Dimtrios Fotiadis","raw_affiliation_strings":["M.E. M\u00fcller Institute for Structural Biology, Biozentrum, University of Basel, Basel, Switzerland","M.E. M\u00fcller Institute for Structural Biology, Biozentrum University of Basel, Basel, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"M.E. M\u00fcller Institute for Structural Biology, Biozentrum, University of Basel, Basel, Switzerland","institution_ids":["https://openalex.org/I1850255"]},{"raw_affiliation_string":"M.E. M\u00fcller Institute for Structural Biology, Biozentrum University of Basel, Basel, Switzerland","institution_ids":["https://openalex.org/I1850255"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058832229","display_name":"Alexej Kedrov","orcid":"https://orcid.org/0000-0001-9117-752X","observed_orcids":["https://orcid.org/0000-0001-9117-752X"]},"institutions":[{"id":"https://openalex.org/I4405272450","display_name":"Biotechnologisches Zentrum","ror":"https://ror.org/046b28292","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4405272450","https://openalex.org/I4405279746","https://openalex.org/I78650965"]},{"id":"https://openalex.org/I78650965","display_name":"Technische Universit\u00e4t Dresden","ror":"https://ror.org/042aqky30","country_code":"DE","type":"education","lineage":["https://openalex.org/I78650965"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Alexej Kedrov","raw_affiliation_strings":["Center of Biotechnology, University of Technology, Dresden, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Biotechnology, University of Technology, Dresden, Germany","institution_ids":["https://openalex.org/I4405272450","https://openalex.org/I78650965"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057353309","display_name":"David A. Cisneros","orcid":"https://orcid.org/0000-0001-9919-0075","observed_orcids":["https://orcid.org/0000-0001-9919-0075"]},"institutions":[{"id":"https://openalex.org/I4405272450","display_name":"Biotechnologisches Zentrum","ror":"https://ror.org/046b28292","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4405272450","https://openalex.org/I4405279746","https://openalex.org/I78650965"]},{"id":"https://openalex.org/I78650965","display_name":"Technische Universit\u00e4t Dresden","ror":"https://ror.org/042aqky30","country_code":"DE","type":"education","lineage":["https://openalex.org/I78650965"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"David Cisneros","raw_affiliation_strings":["Center of Biotechnology, University of Technology, Dresden, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Biotechnology, University of Technology, Dresden, Germany","institution_ids":["https://openalex.org/I4405272450","https://openalex.org/I78650965"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085237343","display_name":"Daniel J. M\u00fcller","orcid":"https://orcid.org/0000-0003-3075-0665","observed_orcids":["https://orcid.org/0000-0003-3075-0665"]},"institutions":[{"id":"https://openalex.org/I4405272450","display_name":"Biotechnologisches Zentrum","ror":"https://ror.org/046b28292","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4405272450","https://openalex.org/I4405279746","https://openalex.org/I78650965"]},{"id":"https://openalex.org/I78650965","display_name":"Technische Universit\u00e4t Dresden","ror":"https://ror.org/042aqky30","country_code":"DE","type":"education","lineage":["https://openalex.org/I78650965"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Daniel J. M\u00fcller","raw_affiliation_strings":["Center of Biotechnology, University of Technology, Dresden, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Biotechnology, University of Technology, Dresden, Germany","institution_ids":["https://openalex.org/I4405272450","https://openalex.org/I78650965"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.03542094,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"279","last_page":"311"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10923","display_name":"Force Microscopy Techniques and Applications","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/3107","display_name":"Atomic and Molecular Physics, and Optics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10923","display_name":"Force Microscopy Techniques and Applications","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/3107","display_name":"Atomic and Molecular Physics, and Optics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.0071000000461936,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/membrane-proteins","display_name":"membrane proteins","score":0.9169999957084656},{"id":"https://openalex.org/keywords/single-molecule-force-spectroscopy","display_name":"single-molecule force spectroscopy","score":0.9980000257492065},{"id":"https://openalex.org/keywords/protein-conformational-change","display_name":"protein conformational change","score":0.9120000004768372},{"id":"https://openalex.org/keywords/protein-flexibility","display_name":"protein flexibility","score":0.5270000100135803},{"id":"https://openalex.org/keywords/transmembrane-helices","display_name":"transmembrane helices","score":0.8220000267028809},{"id":"https://openalex.org/keywords/protein-protein-interaction","display_name":"protein-protein interaction","score":0.9269999861717224},{"id":"https://openalex.org/keywords/protein-unfolding-pathways","display_name":"protein unfolding pathways","score":0.6980000138282776},{"id":"https://openalex.org/keywords/protein-refolding","display_name":"protein refolding","score":0.8149999976158142},{"id":"https://openalex.org/keywords/energy-landscape","display_name":"energy landscape","score":0.968999981880188},{"id":"https://openalex.org/keywords/protein-oligomerization","display_name":"protein oligomerization","score":0.6940000057220459},{"id":"https://openalex.org/keywords/reconstituted-membranes","display_name":"reconstituted membranes","score":0.8090000152587891},{"id":"https://openalex.org/keywords/protein-structure-function-relationship","display_name":"protein structure-function relationship","score":0.5680000185966492}],"concepts":[{"id":"https://openalex.org/C119473381","wikidata":"https://www.wikidata.org/wiki/Q49298","display_name":"Force spectroscopy","level":3,"score":0.8109062910079956},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6085652112960815},{"id":"https://openalex.org/C24530287","wikidata":"https://www.wikidata.org/wiki/Q424204","display_name":"Transmembrane protein","level":3,"score":0.5948015451431274},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5661185383796692},{"id":"https://openalex.org/C144647389","wikidata":"https://www.wikidata.org/wiki/Q423042","display_name":"Membrane protein","level":3,"score":0.564423680305481},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.5367118120193481},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.5328009128570557},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.4726012349128723},{"id":"https://openalex.org/C159467904","wikidata":"https://www.wikidata.org/wiki/Q2001702","display_name":"Chemical physics","level":1,"score":0.4411028027534485},{"id":"https://openalex.org/C102951782","wikidata":"https://www.wikidata.org/wiki/Q49295","display_name":"Atomic force microscopy","level":2,"score":0.43371349573135376},{"id":"https://openalex.org/C59593255","wikidata":"https://www.wikidata.org/wiki/Q901663","display_name":"Molecular dynamics","level":2,"score":0.42932096123695374},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.42647671699523926},{"id":"https://openalex.org/C19472624","wikidata":"https://www.wikidata.org/wiki/Q583851","display_name":"Native state","level":2,"score":0.4212809205055237},{"id":"https://openalex.org/C69308434","wikidata":"https://www.wikidata.org/wiki/Q5160266","display_name":"Conformational entropy","level":3,"score":0.4135211110115051},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.34434226155281067},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.210638165473938},{"id":"https://openalex.org/C147597530","wikidata":"https://www.wikidata.org/wiki/Q369472","display_name":"Computational chemistry","level":1,"score":0.16505670547485352},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.15399566292762756},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.14095598459243774},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-3-540-73924-1_11","doi":"https://doi.org/10.1007/978-3-540-73924-1_11","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-540-73924-1_11","pdf_url":null,"source":{"id":"https://openalex.org/S4210169908","display_name":"Springer series in biophysics","issn_l":"0932-2353","issn":["0932-2353","1868-2561"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Springer Series in Biophysics","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/7","score":0.6700000166893005,"display_name":"Affordable and clean energy"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":134,"referenced_works":["https://openalex.org/W61017702","https://openalex.org/W187856331","https://openalex.org/W1492262300","https://openalex.org/W1492420763","https://openalex.org/W1510667069","https://openalex.org/W1521538637","https://openalex.org/W1536428180","https://openalex.org/W1540419168","https://openalex.org/W1563659068","https://openalex.org/W1572609533","https://openalex.org/W1585115615","https://openalex.org/W1591326119","https://openalex.org/W1644039610","https://openalex.org/W1947778485","https://openalex.org/W1964847866","https://openalex.org/W1965814895","https://openalex.org/W1966386667","https://openalex.org/W1968321705","https://openalex.org/W1969803766","https://openalex.org/W1971273419","https://openalex.org/W1972460929","https://openalex.org/W1973011837","https://openalex.org/W1973897761","https://openalex.org/W1973946193","https://openalex.org/W1978076941","https://openalex.org/W1979244911","https://openalex.org/W1979552135","https://openalex.org/W1988857953","https://openalex.org/W1991755296","https://openalex.org/W1991811230","https://openalex.org/W1992655252","https://openalex.org/W1993114893","https://openalex.org/W1993638389","https://openalex.org/W1993697025","https://openalex.org/W1994069050","https://openalex.org/W1995685967","https://openalex.org/W1997200285","https://openalex.org/W1997263768","https://openalex.org/W1997303616","https://openalex.org/W1998948607","https://openalex.org/W2000577415","https://openalex.org/W2001268252","https://openalex.org/W2002090291","https://openalex.org/W2002472071","https://openalex.org/W2003261014","https://openalex.org/W2006340302","https://openalex.org/W2008972629","https://openalex.org/W2010549225","https://openalex.org/W2011319378","https://openalex.org/W2011733534","https://openalex.org/W2013854174","https://openalex.org/W2020091343","https://openalex.org/W2022777594","https://openalex.org/W2022802646","https://openalex.org/W2023549899","https://openalex.org/W2024461475","https://openalex.org/W2024552758","https://openalex.org/W2025397222","https://openalex.org/W2026444215","https://openalex.org/W2027711565","https://openalex.org/W2027911686","https://openalex.org/W2028811978","https://openalex.org/W2031957405","https://openalex.org/W2032104184","https://openalex.org/W2035279073","https://openalex.org/W2037170319","https://openalex.org/W2037720334","https://openalex.org/W2038042093","https://openalex.org/W2042373127","https://openalex.org/W2043494041","https://openalex.org/W2045723432","https://openalex.org/W2045777307","https://openalex.org/W2045906450","https://openalex.org/W2046106288","https://openalex.org/W2048555993","https://openalex.org/W2049852872","https://openalex.org/W2053802678","https://openalex.org/W2056253643","https://openalex.org/W2058346737","https://openalex.org/W2058912578","https://openalex.org/W2061248759","https://openalex.org/W2061755524","https://openalex.org/W2066075696","https://openalex.org/W2067051318","https://openalex.org/W2069281048","https://openalex.org/W2071837002","https://openalex.org/W2072273138","https://openalex.org/W2073744629","https://openalex.org/W2076475360","https://openalex.org/W2078043123","https://openalex.org/W2082148481","https://openalex.org/W2085458671","https://openalex.org/W2085790749","https://openalex.org/W2086641974","https://openalex.org/W2087046756","https://openalex.org/W2087242837","https://openalex.org/W2090807504","https://openalex.org/W2092071120","https://openalex.org/W2097948220","https://openalex.org/W2098728354","https://openalex.org/W2099095177","https://openalex.org/W2107799535","https://openalex.org/W2108242211","https://openalex.org/W2111646842","https://openalex.org/W2117253642","https://openalex.org/W2118950099","https://openalex.org/W2120504835","https://openalex.org/W2122052848","https://openalex.org/W2125813323","https://openalex.org/W2127159934","https://openalex.org/W2128378659","https://openalex.org/W2129369040","https://openalex.org/W2129664178","https://openalex.org/W2130151473","https://openalex.org/W2133935241","https://openalex.org/W2138150368","https://openalex.org/W2143621044","https://openalex.org/W2144112248","https://openalex.org/W2145082457","https://openalex.org/W2147613694","https://openalex.org/W2149590473","https://openalex.org/W2149963584","https://openalex.org/W2151321627","https://openalex.org/W2152474890","https://openalex.org/W2153890737","https://openalex.org/W2157404832","https://openalex.org/W2160535028","https://openalex.org/W2163884154","https://openalex.org/W2165554797","https://openalex.org/W2166588837","https://openalex.org/W2172039086","https://openalex.org/W2318943783","https://openalex.org/W3150248096","https://openalex.org/W4234689925"],"related_works":["https://openalex.org/W2037964193","https://openalex.org/W2167962205","https://openalex.org/W1639059876","https://openalex.org/W3008293917","https://openalex.org/W7128237967","https://openalex.org/W7064152566","https://openalex.org/W2528809061","https://openalex.org/W1584289029","https://openalex.org/W2074667326","https://openalex.org/W4322484551"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2016-06-24T00:00:00"}
