{"id":"https://openalex.org/W75515743","doi":null,"title":"Chronic refractory dyspnoea--evidence based management.","display_name":"Chronic refractory dyspnoea--evidence based management.","publication_year":2013,"publication_date":"2013-03-01","ids":{"openalex":"https://openalex.org/W75515743","mag":"75515743","pmid":"https://pubmed.ncbi.nlm.nih.gov/23529525"},"language":"en","primary_location":{"id":"pmid:23529525","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23529525","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Australian family physician","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113805083","display_name":"Rachel Wiseman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802773633","display_name":"Christchurch Hospital","ror":"https://ror.org/003nvpm64","country_code":"NZ","type":"healthcare","lineage":["https://openalex.org/I2802773633","https://openalex.org/I4405259026"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Rachel Wiseman","raw_affiliation_strings":["Department of Respiratory Medicine, Christchurch Hospital, New Zealand. rlwiseman@gmail.com","Department of Respiratory Medicine, Christchurch Hospital, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Respiratory Medicine, Christchurch Hospital, New Zealand. rlwiseman@gmail.com","institution_ids":["https://openalex.org/I2802773633"]},{"raw_affiliation_string":"Department of Respiratory Medicine, Christchurch Hospital, New Zealand","institution_ids":["https://openalex.org/I2802773633"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026617187","display_name":"Debra S. Rowett","orcid":"https://orcid.org/0000-0002-8977-0401","observed_orcids":["https://orcid.org/0000-0002-8977-0401"]},"institutions":[{"id":"https://openalex.org/I2802875205","display_name":"Repatriation General Hospital","ror":"https://ror.org/01dsw4m23","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2802875205"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Debra Rowett","raw_affiliation_strings":["Repatriation General Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Repatriation General Hospital","institution_ids":["https://openalex.org/I2802875205"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036602400","display_name":"Peter Allcroft","orcid":"https://orcid.org/0000-0002-2088-3037","observed_orcids":["https://orcid.org/0000-0002-2088-3037"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Peter Allcroft","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079817843","display_name":"Amy P. Abernethy","orcid":"https://orcid.org/0000-0001-6930-8722","observed_orcids":["https://orcid.org/0000-0001-6930-8722"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Amy Abernethy","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5007993808","display_name":"David C. Currow","orcid":"https://orcid.org/0000-0003-1988-1250","observed_orcids":["https://orcid.org/0000-0003-1988-1250"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David C Currow","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.0877,"has_fulltext":false,"cited_by_count":42,"citation_normalized_percentile":{"value":0.91165084,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"42","issue":"3","first_page":"137","last_page":"40"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.538100004196167,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.538100004196167,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12418","display_name":"Respiratory and Cough-Related Research","score":0.13269999623298645,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10198","display_name":"Heart Failure Treatment and Management","score":0.07739999890327454,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dyspnea","display_name":"dyspnea","score":0.9120000004768372},{"id":"https://openalex.org/keywords/chronic-obstructive-pulmonary-disease","display_name":"chronic obstructive pulmonary disease","score":0.8679999709129333},{"id":"https://openalex.org/keywords/heart-failure","display_name":"heart failure","score":0.9980000257492065},{"id":"https://openalex.org/keywords/advanced-cancer","display_name":"advanced cancer","score":0.8130000233650208},{"id":"https://openalex.org/keywords/interstitial-lung-disease","display_name":"interstitial lung disease","score":0.9769999980926514},{"id":"https://openalex.org/keywords/pulmonary-rehabilitation","display_name":"pulmonary rehabilitation","score":0.8289999961853027},{"id":"https://openalex.org/keywords/oral-morphine","display_name":"oral morphine","score":0.7630000114440918},{"id":"https://openalex.org/keywords/oxygen-therapy","display_name":"oxygen therapy","score":0.8029999732971191},{"id":"https://openalex.org/keywords/breathing-exercises","display_name":"breathing exercises","score":0.6320000290870667},{"id":"https://openalex.org/keywords/walking-aids","display_name":"walking aids","score":0.859000027179718},{"id":"https://openalex.org/keywords/symptom-management","display_name":"symptom management","score":0.5019999742507935}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9369775056838989},{"id":"https://openalex.org/C142424586","wikidata":"https://www.wikidata.org/wiki/Q7307572","display_name":"Refractory (planetary science)","level":2,"score":0.7180382609367371},{"id":"https://openalex.org/C2780779891","wikidata":"https://www.wikidata.org/wiki/Q3455927","display_name":"Pulmonary rehabilitation","level":3,"score":0.6019743084907532},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.5747831463813782},{"id":"https://openalex.org/C2778310968","wikidata":"https://www.wikidata.org/wiki/Q14536140","display_name":"Exertion","level":2,"score":0.4762185513973236},{"id":"https://openalex.org/C2778818304","wikidata":"https://www.wikidata.org/wiki/Q1819478","display_name":"Rehabilitation","level":2,"score":0.46729615330696106},{"id":"https://openalex.org/C27415008","wikidata":"https://www.wikidata.org/wiki/Q7256382","display_name":"Psychological intervention","level":2,"score":0.4399341344833374},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.4350849390029907},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3356836140155792},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0},{"id":"https://openalex.org/C87355193","wikidata":"https://www.wikidata.org/wiki/Q411","display_name":"Astrobiology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001569","descriptor_name":"Benzodiazepines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D002908","descriptor_name":"Chronic Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004417","descriptor_name":"Dyspnea","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D004417","descriptor_name":"Dyspnea","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D004417","descriptor_name":"Dyspnea","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009020","descriptor_name":"Morphine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D010102","descriptor_name":"Oxygen Inhalation Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016138","descriptor_name":"Walking","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017563","descriptor_name":"Lung Diseases, Interstitial","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D019636","descriptor_name":"Neurodegenerative Diseases","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D029424","descriptor_name":"Pulmonary Disease, Chronic Obstructive","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:23529525","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23529525","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Australian family physician","raw_type":"Journal Article"},{"id":"pmh:oai:opus.lib.uts.edu.au:10453/116003","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10453/116003","pdf_url":null,"source":{"id":"https://openalex.org/S4306401357","display_name":"UTS ePRESS (University of Technology Sydney)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114017466","host_organization_name":"University of Technology Sydney","host_organization_lineage":["https://openalex.org/I114017466"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"},{"id":"mag:75515743","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23529525","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2007223891","https://openalex.org/W2146250410","https://openalex.org/W1593249833","https://openalex.org/W1509780534","https://openalex.org/W1983263201","https://openalex.org/W2008816151","https://openalex.org/W2959361652","https://openalex.org/W2054960836","https://openalex.org/W2261862479","https://openalex.org/W2554421575"],"abstract_inverted_index":{"BACKGROUND:":[0],"Chronic":[1],"refractory":[2,62],"dyspnoea":[3],"is":[4,66,112,124,135,140],"defined":[5],"as":[6],"breathlessness":[7],"daily":[8],"for":[9,118],"3":[10],"months":[11],"at":[12],"rest":[13],"or":[14],"on":[15],"minimal":[16],"exertion":[17],"where":[18],"contributing":[19],"causes":[20],"have":[21],"been":[22],"treated":[23],"maximally.":[24],"Prevalent":[25],"aetiologies":[26],"include":[27,80],"chronic":[28,61,87],"obstructive":[29,88],"pulmonary":[30,89,91],"disease,":[31,90],"heart":[32],"failure,":[33],"advanced":[34],"cancer":[35],"and":[36,50,114],"interstitial":[37],"lung":[38],"diseases.":[39],"OBJECTIVE:":[40],"To":[41],"distil":[42],"from":[43],"the":[44,56,143],"peer":[45],"reviewed":[46],"literature":[47],"(literature":[48],"search":[49],"guidelines)":[51],"evidence":[52],"that":[53],"can":[54],"guide":[55],"safe,":[57],"symptomatic":[58,138],"management":[59],"of":[60],"dyspnoea.":[63],"DISCUSSION:":[64],"Dyspnoea":[65],"mostly":[67],"multifactorial.":[68],"Each":[69],"reversible":[70],"cause":[71],"should":[72],"be":[73],"managed":[74],"(Level":[75,93,103],"4":[76],"evidence).":[77,95],"Non-pharmacological":[78],"interventions":[79],"walking":[81],"aids,":[82],"breathing":[83],"training":[84],"and,":[85],"in":[86],"rehabilitation":[92],"1":[94,104],"Regular,":[96],"low":[97],"dose,":[98],"sustained":[99],"release":[100],"oral":[101],"morphine":[102],"evidence)":[105],"titrated":[106],"to":[107],"effect":[108],"(with":[109],"regular":[110],"aperients)":[111],"effective":[113,127],"safe.":[115],"Oxygen":[116],"therapy":[117],"patients":[119],"who":[120],"are":[121],"not":[122],"hypoxaemic":[123],"no":[125],"more":[126],"than":[128],"medical":[129],"air.":[130],"If":[131],"a":[132],"therapeutic":[133],"trial":[134],"indicated,":[136],"any":[137],"benefit":[139],"likely":[141],"within":[142],"first":[144],"72":[145],"hours.":[146]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}