{"id":"https://openalex.org/W7546492","doi":null,"title":"Discovery and Characterization of a Novel Microtubule Associated Protein Involved in Cellulose Biosynthesis","display_name":"Discovery and Characterization of a Novel Microtubule Associated Protein Involved in Cellulose Biosynthesis","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W7546492","mag":"7546492"},"language":"en","primary_location":{"id":"pmh:oai:DiVA.org:kth-4812","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4812","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I86987016","host_organization_name":"KTH Royal Institute of Technology","host_organization_lineage":["https://openalex.org/I86987016"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4812","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009638707","display_name":"Alex S. Rajangam","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Alex S. Rajangam","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5009638707"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10869","display_name":"Polysaccharides and Plant Cell Walls","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10869","display_name":"Polysaccharides and Plant Cell Walls","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":0.003800000064074993,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10610","display_name":"Advanced Cellulose Research Studies","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microtubule-associated-proteins","display_name":"microtubule-associated proteins","score":0.9169999957084656},{"id":"https://openalex.org/keywords/cellulose-biosynthesis","display_name":"cellulose biosynthesis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/secondary-cell-wall","display_name":"secondary cell wall","score":0.7689999938011169},{"id":"https://openalex.org/keywords/2-6-dichlorobenzonitrile","display_name":"2,6-dichlorobenzonitrile","score":0.9200000166893005},{"id":"https://openalex.org/keywords/cellulose-biosynthesis-inhibitors","display_name":"cellulose biosynthesis inhibitors","score":0.7820000052452087},{"id":"https://openalex.org/keywords/wood-development","display_name":"wood development","score":0.49900001287460327},{"id":"https://openalex.org/keywords/est-libraries","display_name":"EST libraries","score":0.5299999713897705},{"id":"https://openalex.org/keywords/gene-expression-profiling","display_name":"gene expression profiling","score":0.8109999895095825},{"id":"https://openalex.org/keywords/protein-purification","display_name":"protein purification","score":0.5529999732971191},{"id":"https://openalex.org/keywords/protein-localization","display_name":"protein localization","score":0.5239999890327454},{"id":"https://openalex.org/keywords/overexpression-in-arabidopsis","display_name":"Arabidopsis overexpression","score":0.7170000076293945},{"id":"https://openalex.org/keywords/fiber-properties","display_name":"fiber properties","score":0.4429999887943268}],"concepts":[{"id":"https://openalex.org/C553450214","wikidata":"https://www.wikidata.org/wiki/Q851162","display_name":"Biosynthesis","level":3,"score":0.7477024793624878},{"id":"https://openalex.org/C2779251873","wikidata":"https://www.wikidata.org/wiki/Q80294","display_name":"Cellulose","level":2,"score":0.5209333300590515},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4872795343399048},{"id":"https://openalex.org/C20418707","wikidata":"https://www.wikidata.org/wiki/Q189933","display_name":"Microtubule","level":2,"score":0.4792642295360565},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4615919589996338},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.44305723905563354},{"id":"https://openalex.org/C2780841128","wikidata":"https://www.wikidata.org/wiki/Q5073781","display_name":"Characterization (materials science)","level":2,"score":0.438212513923645},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.32446908950805664},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3240126967430115},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.2051142156124115},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.1910756230354309},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.15321046113967896}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:DiVA.org:kth-4812","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4812","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I86987016","host_organization_name":"KTH Royal Institute of Technology","host_organization_lineage":["https://openalex.org/I86987016"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:7546492","doi":null,"is_oa":false,"landing_page_url":"http://kth.diva-portal.org/smash/get/diva2:14098/FULLTEXT01","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:DiVA.org:kth-4812","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4812","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I86987016","host_organization_name":"KTH Royal Institute of Technology","host_organization_lineage":["https://openalex.org/I86987016"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":242,"referenced_works":["https://openalex.org/W34162735","https://openalex.org/W72184262","https://openalex.org/W177393830","https://openalex.org/W181765173","https://openalex.org/W185362210","https://openalex.org/W791550880","https://openalex.org/W815233466","https://openalex.org/W1488889030","https://openalex.org/W1488926650","https://openalex.org/W1494075612","https://openalex.org/W1504894280","https://openalex.org/W1511214901","https://openalex.org/W1521459199","https://openalex.org/W1526821874","https://openalex.org/W1569119849","https://openalex.org/W1584722432","https://openalex.org/W1585677908","https://openalex.org/W1590240800","https://openalex.org/W1590385027","https://openalex.org/W1592870802","https://openalex.org/W1598147385","https://openalex.org/W1601119178","https://openalex.org/W1636584860","https://openalex.org/W1767772592","https://openalex.org/W1824202545","https://openalex.org/W1893289187","https://openalex.org/W1934886907","https://openalex.org/W1963969404","https://openalex.org/W1965114195","https://openalex.org/W1969239330","https://openalex.org/W1969506908","https://openalex.org/W1970532735","https://openalex.org/W1972567052","https://openalex.org/W1972881818","https://openalex.org/W1973572248","https://openalex.org/W1977737083","https://openalex.org/W1977950017","https://openalex.org/W1978608343","https://openalex.org/W1978855399","https://openalex.org/W1979325051","https://openalex.org/W1981828006","https://openalex.org/W1981946445","https://openalex.org/W1982592107","https://openalex.org/W1982728774","https://openalex.org/W1984882400","https://openalex.org/W1985471440","https://openalex.org/W1985535920","https://openalex.org/W1986719961","https://openalex.org/W1986764013","https://openalex.org/W1990022480","https://openalex.org/W1990652169","https://openalex.org/W1991293840","https://openalex.org/W1992140809","https://openalex.org/W1993713373","https://openalex.org/W1994724896","https://openalex.org/W1995254238","https://openalex.org/W1995697648","https://openalex.org/W1995930436","https://openalex.org/W1996386189","https://openalex.org/W1996442036","https://openalex.org/W1996656972","https://openalex.org/W1997079233","https://openalex.org/W1998601977","https://openalex.org/W2000127256","https://openalex.org/W2000639895","https://openalex.org/W2001743296","https://openalex.org/W2002058224","https://openalex.org/W2002254535","https://openalex.org/W2002364511","https://openalex.org/W2003293851","https://openalex.org/W2003378809","https://openalex.org/W2004841938","https://openalex.org/W2005017098","https://openalex.org/W2005694028","https://openalex.org/W2006240155","https://openalex.org/W2006704086","https://openalex.org/W2008281634","https://openalex.org/W2009540675","https://openalex.org/W2011695624","https://openalex.org/W2012550332","https://openalex.org/W2012995683","https://openalex.org/W2012999385","https://openalex.org/W2013499150","https://openalex.org/W2015000899","https://openalex.org/W2016688698","https://openalex.org/W2016738837","https://openalex.org/W2017959299","https://openalex.org/W2019461117","https://openalex.org/W2020042592","https://openalex.org/W2020518169","https://openalex.org/W2020820615","https://openalex.org/W2023504356","https://openalex.org/W2024007940","https://openalex.org/W2024536005","https://openalex.org/W2030836766","https://openalex.org/W2031479261","https://openalex.org/W2033663882","https://openalex.org/W2033723467","https://openalex.org/W2035018334","https://openalex.org/W2035390791","https://openalex.org/W2036852149","https://openalex.org/W2036852154","https://openalex.org/W2038163496","https://openalex.org/W2038605324","https://openalex.org/W2041134606","https://openalex.org/W2041752034","https://openalex.org/W2044108377","https://openalex.org/W2044715972","https://openalex.org/W2045150844","https://openalex.org/W2045364164","https://openalex.org/W2045510002","https://openalex.org/W2047342085","https://openalex.org/W2048467789","https://openalex.org/W2048903229","https://openalex.org/W2049706494","https://openalex.org/W2050658844","https://openalex.org/W2051435806","https://openalex.org/W2051614114","https://openalex.org/W2051883148","https://openalex.org/W2052625863","https://openalex.org/W2055043387","https://openalex.org/W2057665844","https://openalex.org/W2057997061","https://openalex.org/W2059727911","https://openalex.org/W2060406962","https://openalex.org/W2061399999","https://openalex.org/W2069451540","https://openalex.org/W2069966262","https://openalex.org/W2071044193","https://openalex.org/W2072145229","https://openalex.org/W2073702182","https://openalex.org/W2074403192","https://openalex.org/W2075451508","https://openalex.org/W2076782764","https://openalex.org/W2079175432","https://openalex.org/W2079442979","https://openalex.org/W2080326081","https://openalex.org/W2080530877","https://openalex.org/W2082104619","https://openalex.org/W2082667898","https://openalex.org/W2085500455","https://openalex.org/W2087527157","https://openalex.org/W2090924765","https://openalex.org/W2091070751","https://openalex.org/W2094423864","https://openalex.org/W2095133804","https://openalex.org/W2095488286","https://openalex.org/W2096217862","https://openalex.org/W2098640124","https://openalex.org/W2098747934","https://openalex.org/W2101988799","https://openalex.org/W2102502076","https://openalex.org/W2103301028","https://openalex.org/W2103336806","https://openalex.org/W2105072880","https://openalex.org/W2107479361","https://openalex.org/W2107580421","https://openalex.org/W2108602909","https://openalex.org/W2108733083","https://openalex.org/W2109208274","https://openalex.org/W2111206904","https://openalex.org/W2113937104","https://openalex.org/W2115376659","https://openalex.org/W2116241863","https://openalex.org/W2118104556","https://openalex.org/W2118129329","https://openalex.org/W2119198732","https://openalex.org/W2120105393","https://openalex.org/W2120371919","https://openalex.org/W2120522152","https://openalex.org/W2122662864","https://openalex.org/W2122676114","https://openalex.org/W2122881394","https://openalex.org/W2122963411","https://openalex.org/W2123669969","https://openalex.org/W2124500577","https://openalex.org/W2124534459","https://openalex.org/W2124663138","https://openalex.org/W2124956531","https://openalex.org/W2125346198","https://openalex.org/W2127774996","https://openalex.org/W2128512578","https://openalex.org/W2131510173","https://openalex.org/W2132552126","https://openalex.org/W2132926880","https://openalex.org/W2133097991","https://openalex.org/W2136280642","https://openalex.org/W2137458297","https://openalex.org/W2137630615","https://openalex.org/W2139787368","https://openalex.org/W2140658409","https://openalex.org/W2140978794","https://openalex.org/W2142364393","https://openalex.org/W2142410456","https://openalex.org/W2142726703","https://openalex.org/W2143310104","https://openalex.org/W2145268834","https://openalex.org/W2145524208","https://openalex.org/W2146058063","https://openalex.org/W2147161439","https://openalex.org/W2147608991","https://openalex.org/W2149249386","https://openalex.org/W2150304779","https://openalex.org/W2150826299","https://openalex.org/W2150960943","https://openalex.org/W2151815774","https://openalex.org/W2151831732","https://openalex.org/W2154342116","https://openalex.org/W2156622081","https://openalex.org/W2156793936","https://openalex.org/W2158714788","https://openalex.org/W2158856532","https://openalex.org/W2159266221","https://openalex.org/W2160644678","https://openalex.org/W2161000760","https://openalex.org/W2161076219","https://openalex.org/W2161320070","https://openalex.org/W2161732286","https://openalex.org/W2165091352","https://openalex.org/W2166265186","https://openalex.org/W2166354876","https://openalex.org/W2167225162","https://openalex.org/W2168176123","https://openalex.org/W2168813941","https://openalex.org/W2169596130","https://openalex.org/W2171155307","https://openalex.org/W2171405769","https://openalex.org/W2183827027","https://openalex.org/W2274656947","https://openalex.org/W2288250218","https://openalex.org/W2292052495","https://openalex.org/W2334292465","https://openalex.org/W2397259150","https://openalex.org/W2501471262","https://openalex.org/W2501841283","https://openalex.org/W2511555256","https://openalex.org/W2912643680","https://openalex.org/W2944572324","https://openalex.org/W2946980822","https://openalex.org/W2992110951","https://openalex.org/W3158788624","https://openalex.org/W3215951544"],"related_works":["https://openalex.org/W4391227732","https://openalex.org/W2131713655","https://openalex.org/W2117571889","https://openalex.org/W1274669421","https://openalex.org/W7028609699","https://openalex.org/W2516578862","https://openalex.org/W653703959","https://openalex.org/W74975874","https://openalex.org/W2078865215","https://openalex.org/W2143056493"],"abstract_inverted_index":{"Cell":[0],"walls":[1],"are":[2,16,31],"a":[3,84,88,145,150,172,202,306,314],"distinct":[4],"feature":[5],"of":[6,63,95,117,125,144,216,279],"plants":[7],"and":[8,14,37,44,75,142,176,195,211,225,251,268,320],"their":[9,28],"chemical":[10],"constituents,":[11],"cellulose,":[12,23],"hemicelluloses":[13],"lignin,":[15],"economically":[17],"valuable.":[18],"Plant":[19],"fibres":[20],"rich":[21],"in":[22,27,34,82,154,208,219,247,249,252,260,291,326],"which":[24],"mainly":[25],"resides":[26],"cell":[29,328],"wall,":[30],"traditionally":[32],"used":[33,181,200,246,264,273],"making":[35],"paper":[36],"textiles.":[38],"The":[39,61,93,197],"changing":[40],"global":[41],"economic":[42],"situation":[43],"environmental":[45],"concerns":[46],"have":[47,71],"imparted":[48],"necessity":[49],"for":[50,90,185,204,212,234,265],"renewable,":[51],"but":[52],"at":[53],"the":[54,96,140,167,177,213,217,235,269,276,280,286,292,297],"same":[55,270],"time":[56],"value":[57],"added":[58],"cellulosic":[59],"materials.":[60],"Department":[62],"Wood":[64],"Biotechnology,":[65],"KTH":[66],"together":[67],"with":[68,104,121,149,171,223],"its":[69,161],"collaborators,":[70],"established":[72],"EST":[73],"libraries":[74],"performed":[76],"transcript":[77],"profiling":[78],"during":[79,99,323],"wood":[80,91],"development":[81],"poplar,":[83],"tree":[85],"considered":[86],"as":[87,110,201],"model":[89,243,293],"development.":[92],"majority":[94],"genes":[97,127],"upregulated":[98,147],"cellulose":[100,315,324],"biosynthesis":[101,316,325],"encode":[102,119],"proteins":[103,120],"known":[105],"or":[106],"predictable":[107],"functions,":[108],"such":[109],"carbohydrate":[111],"active":[112],"enzymes":[113],"(CAzymes).":[114],"However,":[115],"some":[116],"them":[118],"unknown":[122,152],"functions.":[123],"Characterization":[124],"these":[126],"will":[128],"potentially":[129],"give":[130],"additional":[131],"opportunities":[132],"to":[133,182,274,313],"modify":[134],"fibre":[135],"properties.":[136],"This":[137],"thesis":[138],"describes":[139],"discovery":[141,163],"characterization":[143,168],"highly":[146],"gene":[148,288],"previously":[151],"function":[153],"poplar":[155],"xylem,":[156],"here":[157],"denoted":[158],"PttMAP20.":[159],"Following":[160],"early":[162],"by":[164,239],"mRNA":[165],"profiling,":[166],"was":[169,180,232,263,272],"initiated":[170],"thorough":[173],"bioinformatic":[174],"analysis,":[175],"knowledge":[178],"obtained":[179,299],"devise":[183],"techniques":[184],"further":[186],"functional":[187],"analysis.":[188],"Specific":[189],"antibodies":[190,198],"were":[191,199,245,289],"raised,":[192],"affinity":[193],"purified":[194],"characterized.":[196],"tool":[203],"screening":[205],"recombinant":[206],"expression":[207],"E.":[209],"coli":[210],"cellular":[214],"localization":[215,266],"protein":[218,257,310],"plant":[220,294],"tissues,":[221],"visualized":[222],"confocal":[224],"transmission":[226],"electron":[227],"microscopy.":[228],"A":[229],"purification":[230],"protocol":[231],"developed":[233],"expressed":[236,259],"protein,":[237],"followed":[238],"biochemical":[240],"characterization.":[241],"Appropriate":[242],"systems":[244],"both":[248],"vivo":[250],"vitro":[253],"studies.":[254],"Fluorescently":[255],"labelled":[256],"transiently":[258],"tobacco":[261],"leaves":[262],"studies":[267],"system":[271],"characterize":[275],"molecular":[277],"properties":[278],"protein.":[281],"Phenotypes":[282],"arising":[283],"from":[284],"overexpressing":[285],"PttMAP20":[287,304],"traced":[290],"Arabidopsis.":[295],"All":[296],"results":[298],"so":[300],"far":[301],"indicate":[302],"that":[303,311],"is":[305,321],"novel":[307],"microtubule":[308],"associated":[309],"binds":[312],"inhibitor,":[317],"DCB":[318],"(2,6-dichlorobenzonitrile)":[319],"required":[322],"secondary":[327],"walls.":[329]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-06-24T00:00:00"}
