{"id":"https://openalex.org/W75312302","doi":null,"title":"The muscle-bone unit in adulthood: influence of sex, height, age and gynecological history on the bone mineral content and muscle cross-sectional area.","display_name":"The muscle-bone unit in adulthood: influence of sex, height, age and gynecological history on the bone mineral content and muscle cross-sectional area.","publication_year":2006,"publication_date":"2006-04-01","ids":{"openalex":"https://openalex.org/W75312302","mag":"75312302","pmid":"https://pubmed.ncbi.nlm.nih.gov/16849832"},"language":"en","primary_location":{"id":"pmid:16849832","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16849832","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of musculoskeletal & neuronal interactions","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Z Sumnik","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Z Sumnik","raw_affiliation_strings":["Children's Hospital, University of Cologne, Cologne, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children's Hospital, University of Cologne, Cologne, Germany","institution_ids":["https://openalex.org/I180923762"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114260744","display_name":"Christof Land","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C Land","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020012847","display_name":"Silke Coburger","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S Coburger","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050284956","display_name":"Christina Maria Neu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C Neu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072545388","display_name":"Friedrich Manz","orcid":"https://orcid.org/0000-0002-7168-5110","observed_orcids":["https://orcid.org/0000-0002-7168-5110"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F Manz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025210614","display_name":"Karel Hrach","orcid":"https://orcid.org/0000-0002-7012-053X","observed_orcids":["https://orcid.org/0000-0002-7012-053X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K Hrach","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5007481762","display_name":"E Schoenau","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E Schoenau","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.7746,"has_fulltext":false,"cited_by_count":29,"citation_normalized_percentile":{"value":0.9152448,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"6","issue":"2","first_page":"195","last_page":"200"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12279","display_name":"Body Composition Measurement Techniques","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10992","display_name":"Forensic Anthropology and Bioarchaeology Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1204","display_name":"Archeology (arts and humanities)"},"field":{"id":"https://openalex.org/fields/12","display_name":"Arts and Humanities"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bone-mineral-content","display_name":"bone mineral content","score":0.9869999885559082},{"id":"https://openalex.org/keywords/muscle-cross-sectional-area","display_name":"muscle cross-sectional area","score":0.996999979019165},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.8100000023841858},{"id":"https://openalex.org/keywords/body-height","display_name":"body height","score":0.8939999938011169},{"id":"https://openalex.org/keywords/age","display_name":"age","score":0.5239999890327454},{"id":"https://openalex.org/keywords/gynecological-history","display_name":"gynecological history","score":0.9440000057220459},{"id":"https://openalex.org/keywords/age-at-menarche","display_name":"age at menarche","score":0.828000009059906},{"id":"https://openalex.org/keywords/number-of-pregnancies","display_name":"number of pregnancies","score":0.7620000243186951},{"id":"https://openalex.org/keywords/lactation-duration","display_name":"lactation length","score":0.8569999933242798},{"id":"https://openalex.org/keywords/oral-contraception","display_name":"oral contraception","score":0.8949999809265137},{"id":"https://openalex.org/keywords/premenopausal-women","display_name":"premenopausal women","score":0.8009999990463257},{"id":"https://openalex.org/keywords/middle-aged-men","display_name":"middle-aged men","score":0.6549999713897705},{"id":"https://openalex.org/keywords/peripheral-quantitative-computed-tomography","display_name":"peripheral quantitative computed tomography","score":0.6949999928474426}],"concepts":[{"id":"https://openalex.org/C4258228","wikidata":"https://www.wikidata.org/wiki/Q492514","display_name":"Menarche","level":2,"score":0.8035299181938171},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7526838779449463},{"id":"https://openalex.org/C2777425516","wikidata":"https://www.wikidata.org/wiki/Q17083560","display_name":"Quantitative computed tomography","level":4,"score":0.5589503645896912},{"id":"https://openalex.org/C142052008","wikidata":"https://www.wikidata.org/wiki/Q954027","display_name":"Cross-sectional study","level":2,"score":0.5231867432594299},{"id":"https://openalex.org/C2776886416","wikidata":"https://www.wikidata.org/wiki/Q4941567","display_name":"Bone mineral","level":3,"score":0.49191975593566895},{"id":"https://openalex.org/C2780214079","wikidata":"https://www.wikidata.org/wiki/Q228537","display_name":"Forearm","level":2,"score":0.42756733298301697},{"id":"https://openalex.org/C2992594941","wikidata":"https://www.wikidata.org/wiki/Q2304401","display_name":"Bone mineral content","level":4,"score":0.4206865429878235},{"id":"https://openalex.org/C205545832","wikidata":"https://www.wikidata.org/wiki/Q17156455","display_name":"Young adult","level":2,"score":0.4136059880256653},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.36696696281433105},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.28484347462654114},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.2567550241947174},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.19668316841125488},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001827","descriptor_name":"Body Height","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D001846","descriptor_name":"Bone Development","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D003276","descriptor_name":"Contraceptives, Oral","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007774","descriptor_name":"Lactation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008572","descriptor_name":"Menarche","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011884","descriptor_name":"Radius","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D011884","descriptor_name":"Radius","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012727","descriptor_name":"Sex Characteristics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015519","descriptor_name":"Bone Density","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D017697","descriptor_name":"Premenopause","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:16849832","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16849832","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of musculoskeletal & neuronal interactions","raw_type":"Journal Article"},{"id":"mag:75312302","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16849832","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1964644558","https://openalex.org/W1975059727","https://openalex.org/W1979826291","https://openalex.org/W2015816951","https://openalex.org/W2016575849","https://openalex.org/W2019762507","https://openalex.org/W2021133673","https://openalex.org/W2025319068","https://openalex.org/W2026084643","https://openalex.org/W2037084669","https://openalex.org/W2040603894","https://openalex.org/W2043192944","https://openalex.org/W2048626317","https://openalex.org/W2085922591","https://openalex.org/W2110819242","https://openalex.org/W2130934825","https://openalex.org/W2137450031","https://openalex.org/W2160287478","https://openalex.org/W2164512967","https://openalex.org/W2171589125","https://openalex.org/W2258234608"],"related_works":["https://openalex.org/W2163620758","https://openalex.org/W2100622506","https://openalex.org/W2110819242","https://openalex.org/W1978696092","https://openalex.org/W2789209469","https://openalex.org/W2171905902","https://openalex.org/W2092110716","https://openalex.org/W2093388282","https://openalex.org/W2090399505","https://openalex.org/W2011679287"],"abstract_inverted_index":{"Bone":[0],"and":[1,23,43,71,96,178],"muscle":[2,24,31],"development":[3],"are":[4],"both":[5,121,139],"strongly":[6],"influenced":[7],"by":[8],"sex":[9],"hormones.":[10],"The":[11,76,108,169],"purpose":[12],"of":[13,66,69,73,90,159,163,174],"this":[14],"study":[15,77],"was":[16,78,111],"to":[17,53],"examine":[18],"the":[19,59,91,160,172],"changes":[20],"in":[21,36,44,120,132,135,148,151,184],"bone":[22,182],"parameters":[25,177],"(bone":[26],"mineral":[27],"content":[28],"-":[29,34],"BMC,":[30],"cross-sectional":[32],"area":[33],"MA)":[35],"130":[37],"men":[38],"aged":[39,48],"31":[40],"-60":[41],"years,":[42],"180":[45],"pre-menopausal":[46],"women":[47],"30-53":[49],"years":[50],"with":[51,58],"respect":[52],"age,":[54],"body":[55,101,118],"height":[56,102,119],"and,":[57],"women,":[60],"their":[61],"gynecological":[62,164],"history":[63,165],"(age-at-menarche,":[64],"number":[65],"pregnancies,":[67],"duration":[68],"lactation":[70],"use":[72],"oral":[74],"contraception).":[75],"performed":[79],"using":[80],"peripheral":[81],"quantitative":[82],"computed":[83],"tomography":[84],"(pQCT)":[85],"at":[86],"a":[87,143],"65%":[88],"site":[89],"forearm":[92],"length.":[93],"Both":[94],"BMC":[95,127],"MA":[97,123],"were":[98,128],"dependent":[99,112],"on":[100,106,114,117,166],"(p<0.0001),":[103],"but":[104],"not":[105],"age.":[107],"BMC/MA":[109,146,179],"ratio":[110,147,180],"neither":[113],"age":[115],"nor":[116],"genders.":[122],"as":[124,126],"well":[125],"found":[129,155],"significantly":[130,144],"higher":[131,145],"males":[133,152],"than":[134,150],"females":[136,149],"(p<0.0001":[137],"for":[138],"variables).":[140],"We":[141,154],"observed":[142],"(p<0.0001).":[153],"no":[156],"effect":[157],"either":[158],"analyzed":[161],"variables":[162],"bone/muscle":[167],"characteristics.":[168],"findings":[170],"highlight":[171],"necessity":[173],"involving":[175],"height-adjusted":[176],"into":[181],"analysis":[183],"adults.":[185]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}