{"id":"https://openalex.org/W748047178","doi":null,"title":"Genetic variation underlying anxiety-like behaviour in laboratory mouse strains","display_name":"Genetic variation underlying anxiety-like behaviour in laboratory mouse strains","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W748047178","mag":"748047178"},"language":"en","primary_location":{"id":"pmh:oai:eprints.brighton.ac.uk:12314","doi":null,"is_oa":false,"landing_page_url":"http://eprints.brighton.ac.uk/12314/1/BRUNO%20GOLDING%20THESIS%20FINAL%20Front%20page.pdf","pdf_url":"http://eprints.brighton.ac.uk/12314/1/BRUNO%20GOLDING%20THESIS%20FINAL%20Front%20page.pdf","source":{"id":"https://openalex.org/S4306401758","display_name":"University of Brighton Repository (University of Brighton)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I71637028","host_organization_name":"University of Brighton","host_organization_lineage":["https://openalex.org/I71637028"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070265868","display_name":"Bruno Golding","orcid":"https://orcid.org/0009-0002-6350-5375","observed_orcids":["https://orcid.org/0009-0002-6350-5375"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Bruno Golding","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5070265868"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11001","display_name":"Renin-Angiotensin System Studies","score":0.9057999849319458,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11001","display_name":"Renin-Angiotensin System Studies","score":0.9057999849319458,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.05530000105500221,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.004699999932199717,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/anxiety-like-behavior","display_name":"anxiety-like behavior","score":0.984000027179718},{"id":"https://openalex.org/keywords/mouse-strains","display_name":"mouse strains","score":0.6209999918937683},{"id":"https://openalex.org/keywords/genetic-variation","display_name":"genetic variation","score":0.7910000085830688},{"id":"https://openalex.org/keywords/losartan","display_name":"losartan","score":0.8109999895095825},{"id":"https://openalex.org/keywords/anxiolytic-effects","display_name":"anxiolytic effects","score":0.8389999866485596},{"id":"https://openalex.org/keywords/receptor-binding-sites","display_name":"receptor binding sites","score":0.6430000066757202}],"concepts":[{"id":"https://openalex.org/C2778334786","wikidata":"https://www.wikidata.org/wiki/Q1586270","display_name":"Variation (astronomy)","level":2,"score":0.6412793397903442},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.5746190547943115},{"id":"https://openalex.org/C68873052","wikidata":"https://www.wikidata.org/wiki/Q349856","display_name":"Genetic variation","level":3,"score":0.5002539157867432},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4668021500110626},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4163222014904022},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.38701409101486206},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.3577224314212799},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.13326776027679443},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10996398329734802},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.09225833415985107},{"id":"https://openalex.org/C44870925","wikidata":"https://www.wikidata.org/wiki/Q37547","display_name":"Astrophysics","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:eprints.brighton.ac.uk:12314","doi":null,"is_oa":false,"landing_page_url":"http://eprints.brighton.ac.uk/12314/1/BRUNO%20GOLDING%20THESIS%20FINAL%20Front%20page.pdf","pdf_url":"http://eprints.brighton.ac.uk/12314/1/BRUNO%20GOLDING%20THESIS%20FINAL%20Front%20page.pdf","source":{"id":"https://openalex.org/S4306401758","display_name":"University of Brighton Repository (University of Brighton)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I71637028","host_organization_name":"University of Brighton","host_organization_lineage":["https://openalex.org/I71637028"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"pmh:hdl:10068/970199","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10068/970199","pdf_url":null,"source":{"id":"https://openalex.org/S4377196900","display_name":"OpenGrey (Institut de l'Information Scientifique et Technique)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1295345811","host_organization_name":"Institut de l'Information Scientifique et Technique","host_organization_lineage":["https://openalex.org/I1295345811"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"U - Thesis"},{"id":"mag:748047178","doi":null,"is_oa":false,"landing_page_url":"https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.518245","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.6240000128746033}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":113,"referenced_works":["https://openalex.org/W91842139","https://openalex.org/W137118570","https://openalex.org/W294850229","https://openalex.org/W1499968412","https://openalex.org/W1525464385","https://openalex.org/W1533731827","https://openalex.org/W1587563234","https://openalex.org/W1608618183","https://openalex.org/W1732201504","https://openalex.org/W1760461988","https://openalex.org/W1899532003","https://openalex.org/W1914747759","https://openalex.org/W1964431010","https://openalex.org/W1971543162","https://openalex.org/W1972600765","https://openalex.org/W1975830080","https://openalex.org/W1979040830","https://openalex.org/W1980243405","https://openalex.org/W1980771632","https://openalex.org/W1982272489","https://openalex.org/W1985010774","https://openalex.org/W1985500659","https://openalex.org/W1987205676","https://openalex.org/W1988994847","https://openalex.org/W1991157605","https://openalex.org/W1992934690","https://openalex.org/W1993623170","https://openalex.org/W1994142889","https://openalex.org/W1994356589","https://openalex.org/W1994781509","https://openalex.org/W1997659535","https://openalex.org/W1997686063","https://openalex.org/W1998407917","https://openalex.org/W2004681621","https://openalex.org/W2005480323","https://openalex.org/W2006589746","https://openalex.org/W2008113818","https://openalex.org/W2008932788","https://openalex.org/W2010627562","https://openalex.org/W2011815930","https://openalex.org/W2018667935","https://openalex.org/W2021036812","https://openalex.org/W2021661103","https://openalex.org/W2023741805","https://openalex.org/W2024388318","https://openalex.org/W2026198012","https://openalex.org/W2026397649","https://openalex.org/W2026575204","https://openalex.org/W2029094565","https://openalex.org/W2030261100","https://openalex.org/W2031150814","https://openalex.org/W2034767261","https://openalex.org/W2037070147","https://openalex.org/W2038363008","https://openalex.org/W2038896406","https://openalex.org/W2043884992","https://openalex.org/W2044814048","https://openalex.org/W2045907417","https://openalex.org/W2047194297","https://openalex.org/W2047507517","https://openalex.org/W2048235511","https://openalex.org/W2048770882","https://openalex.org/W2049904238","https://openalex.org/W2049931741","https://openalex.org/W2052151503","https://openalex.org/W2052534100","https://openalex.org/W2052969372","https://openalex.org/W2056322364","https://openalex.org/W2056394823","https://openalex.org/W2057841351","https://openalex.org/W2058148588","https://openalex.org/W2063897756","https://openalex.org/W2067830186","https://openalex.org/W2067877875","https://openalex.org/W2070374666","https://openalex.org/W2071922213","https://openalex.org/W2079404351","https://openalex.org/W2081788716","https://openalex.org/W2082014547","https://openalex.org/W2083290251","https://openalex.org/W2086320012","https://openalex.org/W2089264371","https://openalex.org/W2092265525","https://openalex.org/W2096162705","https://openalex.org/W2102027817","https://openalex.org/W2104419150","https://openalex.org/W2107277218","https://openalex.org/W2111329465","https://openalex.org/W2111408945","https://openalex.org/W2114224597","https://openalex.org/W2118016894","https://openalex.org/W2122936122","https://openalex.org/W2125155028","https://openalex.org/W2127695694","https://openalex.org/W2128862717","https://openalex.org/W2129053556","https://openalex.org/W2132110395","https://openalex.org/W2132193621","https://openalex.org/W2134770471","https://openalex.org/W2142459107","https://openalex.org/W2143549199","https://openalex.org/W2145366887","https://openalex.org/W2145917613","https://openalex.org/W2148083750","https://openalex.org/W2149319043","https://openalex.org/W2151594784","https://openalex.org/W2159766146","https://openalex.org/W2164490909","https://openalex.org/W2209434885","https://openalex.org/W2231394739","https://openalex.org/W2291252724","https://openalex.org/W2296932841","https://openalex.org/W7100882025"],"related_works":["https://openalex.org/W2909449964","https://openalex.org/W7033069306","https://openalex.org/W7048443077","https://openalex.org/W7010190657","https://openalex.org/W2247293059","https://openalex.org/W2278242888","https://openalex.org/W2042651197","https://openalex.org/W6893003915","https://openalex.org/W7053062048","https://openalex.org/W2058793862"],"abstract_inverted_index":{"Strain":[0],"differences":[1],"have":[2],"previously":[3],"been":[4],"\\nobserved":[5,60],"in":[6,20,24,38],"the":[7,11,33,39,43,46],"anxiolytic":[8],"effect":[9,34],"of":[10,35,42,48],"Angiotensin":[12],"Type":[13],"I":[14],"receptor":[15,50],"(AT1":[16],"R)":[17],"\\nantagonist":[18],"losartan":[19],"mice.":[21],"Structural":[22],"variation":[23],"key":[25],"binding":[26],"sites,":[27],"AT1":[28,31],"\\nreceptor":[29],"binding,":[30],"expression,":[32],"a":[36],"microsatellite":[37],"\\npromoter":[40],"region":[41],"gene":[44],"and":[45],"influence":[47],"angiotensin":[49],"\\nassociated":[51],"protein":[52],"(ATRAP)":[53],"were":[54],"investigated":[55],"for":[56],"association":[57],"with":[58],"this":[59],"behavioural":[61],"variation.":[62]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}
