{"id":"https://openalex.org/W72465079","doi":"https://doi.org/10.1016/s0074-7742(07)82010-1","title":"Chemokines and Chemokine Receptors: Multipurpose Players in Neuroinflammation","display_name":"Chemokines and Chemokine Receptors: Multipurpose Players in Neuroinflammation","publication_year":2007,"publication_date":"2007-01-01","ids":{"openalex":"https://openalex.org/W72465079","doi":"https://doi.org/10.1016/s0074-7742(07)82010-1","mag":"72465079","pmid":"https://pubmed.ncbi.nlm.nih.gov/17678962"},"language":"en","primary_location":{"id":"doi:10.1016/s0074-7742(07)82010-1","doi":"https://doi.org/10.1016/s0074-7742(07)82010-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0074-7742(07)82010-1","pdf_url":null,"source":{"id":"https://openalex.org/S59060466","display_name":"International review of neurobiology","issn_l":"0074-7742","issn":["0074-7742","2162-5514"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Review of Neurobiology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W632564768","display_name":"Neuroinflammation in Neuronal Death and Repair"},"type":"book-chapter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034732141","display_name":"Richard M. Ransohoff","orcid":"https://orcid.org/0000-0003-0175-6910","observed_orcids":["https://orcid.org/0000-0003-0175-6910"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]},{"id":"https://openalex.org/I4405287411","display_name":"Cleveland Clinic Research","ror":"https://ror.org/053229s83","country_code":"US","type":"facility","lineage":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard M. Ransohoff","raw_affiliation_strings":["Neuroinflammation Research Center, Department of Neurosciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA","Mellen Center for MS Treatment and Research, Cleveland Clinic, Cleveland Ohio 44195, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuroinflammation Research Center, Department of Neurosciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA","institution_ids":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]},{"raw_affiliation_string":"Mellen Center for MS Treatment and Research, Cleveland Clinic, Cleveland Ohio 44195, USA","institution_ids":["https://openalex.org/I1316902750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100352454","display_name":"Liping Liu","orcid":"https://orcid.org/0000-0003-2943-055X","observed_orcids":["https://orcid.org/0000-0003-2943-055X"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]},{"id":"https://openalex.org/I4405287411","display_name":"Cleveland Clinic Research","ror":"https://ror.org/053229s83","country_code":"US","type":"facility","lineage":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"LiPing Liu","raw_affiliation_strings":["Neuroinflammation Research Center, Department of Neurosciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuroinflammation Research Center, Department of Neurosciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA","institution_ids":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013624172","display_name":"Astrid E. Cardona","orcid":"https://orcid.org/0000-0002-5093-8078","observed_orcids":["https://orcid.org/0000-0002-5093-8078"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]},{"id":"https://openalex.org/I4405287411","display_name":"Cleveland Clinic Research","ror":"https://ror.org/053229s83","country_code":"US","type":"facility","lineage":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Astrid E. Cardona","raw_affiliation_strings":["Neuroinflammation Research Center, Department of Neurosciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuroinflammation Research Center, Department of Neurosciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA","institution_ids":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":26.9726,"has_fulltext":false,"cited_by_count":158,"citation_normalized_percentile":{"value":0.99578947,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"82","issue":null,"first_page":"187","last_page":"204"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11532","display_name":"Chemokine receptors and signaling","score":0.9667999744415283,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11532","display_name":"Chemokine receptors and signaling","score":0.9667999744415283,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.029500000178813934,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chemokines","display_name":"chemokines","score":1.0},{"id":"https://openalex.org/keywords/chemokine-receptors","display_name":"chemokine receptors","score":1.0},{"id":"https://openalex.org/keywords/neuroinflammation","display_name":"neuroinflammation","score":0.9290000200271606},{"id":"https://openalex.org/keywords/g-protein-coupled-receptors","display_name":"G protein-coupled receptors","score":0.9240000247955322},{"id":"https://openalex.org/keywords/central-nervous-system-development","display_name":"central nervous system development","score":0.8209999799728394},{"id":"https://openalex.org/keywords/chemokine-receptor-blockade","display_name":"chemokine receptor blockade","score":0.7049999833106995},{"id":"https://openalex.org/keywords/neuromodulation","display_name":"neuromodulation","score":0.7770000100135803},{"id":"https://openalex.org/keywords/chemotaxis","display_name":"chemotaxis","score":0.7160000205039978},{"id":"https://openalex.org/keywords/organogenesis","display_name":"organogenesis","score":0.5519999861717224}],"concepts":[{"id":"https://openalex.org/C13373296","wikidata":"https://www.wikidata.org/wiki/Q421866","display_name":"Chemokine","level":3,"score":0.7139481902122498},{"id":"https://openalex.org/C12823836","wikidata":"https://www.wikidata.org/wiki/Q24720618","display_name":"Chemokine receptor","level":4,"score":0.6235633492469788},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5909574031829834},{"id":"https://openalex.org/C87753298","wikidata":"https://www.wikidata.org/wiki/Q17157137","display_name":"Neuroinflammation","level":3,"score":0.5896178483963013},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5784205198287964},{"id":"https://openalex.org/C140944930","wikidata":"https://www.wikidata.org/wiki/Q18026345","display_name":"CCR10","level":5,"score":0.5244032144546509},{"id":"https://openalex.org/C129013479","wikidata":"https://www.wikidata.org/wiki/Q21111916","display_name":"CCR1","level":5,"score":0.49979734420776367},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4570172131061554},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.44702601432800293},{"id":"https://openalex.org/C54166955","wikidata":"https://www.wikidata.org/wiki/Q658145","display_name":"Chemotaxis","level":3,"score":0.4271339476108551},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.41330254077911377},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.14503797888755798},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002630","descriptor_name":"Chemotactic Factors","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D007962","descriptor_name":"Leukocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007962","descriptor_name":"Leukocytes","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008262","descriptor_name":"Macrophage Activation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009000","descriptor_name":"Monocytes","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009420","descriptor_name":"Nervous System","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D009422","descriptor_name":"Nervous System Diseases","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D009422","descriptor_name":"Nervous System Diseases","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D009444","descriptor_name":"Neuritis, Autoimmune, Experimental","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009836","descriptor_name":"Oligodendroglia","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D017628","descriptor_name":"Microglia","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D017628","descriptor_name":"Microglia","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018925","descriptor_name":"Chemokines","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D019707","descriptor_name":"Receptors, Chemokine","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D020523","descriptor_name":"Chemokines, CX3C","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054428","descriptor_name":"Chemokine CX3CL1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0074-7742(07)82010-1","doi":"https://doi.org/10.1016/s0074-7742(07)82010-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0074-7742(07)82010-1","pdf_url":null,"source":{"id":"https://openalex.org/S59060466","display_name":"International review of neurobiology","issn_l":"0074-7742","issn":["0074-7742","2162-5514"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Review of Neurobiology","raw_type":"book-chapter"},{"id":"pmid:17678962","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17678962","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International review of neurobiology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9074000120162964,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":46,"referenced_works":["https://openalex.org/W73990037","https://openalex.org/W94483482","https://openalex.org/W1765057352","https://openalex.org/W1975164266","https://openalex.org/W1979056048","https://openalex.org/W1992656196","https://openalex.org/W2006065580","https://openalex.org/W2008741766","https://openalex.org/W2010745090","https://openalex.org/W2018173754","https://openalex.org/W2021898378","https://openalex.org/W2025085537","https://openalex.org/W2025732663","https://openalex.org/W2031733803","https://openalex.org/W2032546399","https://openalex.org/W2039438606","https://openalex.org/W2049106125","https://openalex.org/W2054989216","https://openalex.org/W2057029309","https://openalex.org/W2061631515","https://openalex.org/W2069002586","https://openalex.org/W2070614971","https://openalex.org/W2080932190","https://openalex.org/W2086237072","https://openalex.org/W2097452332","https://openalex.org/W2098853912","https://openalex.org/W2099625699","https://openalex.org/W2102628016","https://openalex.org/W2111748635","https://openalex.org/W2113107925","https://openalex.org/W2113238601","https://openalex.org/W2113804090","https://openalex.org/W2116495710","https://openalex.org/W2117908470","https://openalex.org/W2122412498","https://openalex.org/W2124775506","https://openalex.org/W2126972955","https://openalex.org/W2132271411","https://openalex.org/W2133338038","https://openalex.org/W2139485237","https://openalex.org/W2145738273","https://openalex.org/W2148740102","https://openalex.org/W2161057248","https://openalex.org/W2169989044","https://openalex.org/W2417396370","https://openalex.org/W6725031957"],"related_works":["https://openalex.org/W2011700298","https://openalex.org/W1595732671","https://openalex.org/W2028762442","https://openalex.org/W2149467065","https://openalex.org/W2007814599","https://openalex.org/W2105390911","https://openalex.org/W996398452","https://openalex.org/W1585492421","https://openalex.org/W111252450","https://openalex.org/W131358220"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":13},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":11},{"year":2014,"cited_by_count":16},{"year":2013,"cited_by_count":14},{"year":2012,"cited_by_count":8}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}