{"id":"https://openalex.org/W7225834240","doi":"https://doi.org/10.64898/2026.11.10.765620","title":"Sensory context gates oxytocin effects on auditory processing in macaques","display_name":"Sensory context gates oxytocin effects on auditory processing in macaques","publication_year":2026,"publication_date":"2026-11-11","ids":{"openalex":"https://openalex.org/W7225834240","doi":"https://doi.org/10.64898/2026.11.10.765620"},"language":"en","primary_location":{"id":"doi:10.64898/2026.11.10.765620","doi":"https://doi.org/10.64898/2026.11.10.765620","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.11.10.765620","pdf_url":null,"source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.64898/2026.11.10.765620","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050593009","display_name":"Mathilda Froesel","orcid":"https://orcid.org/0000-0003-1222-6317","observed_orcids":["https://orcid.org/0000-0003-1222-6317"]},"institutions":[{"id":"https://openalex.org/I99464096","display_name":"KU Leuven","ror":"https://ror.org/05f950310","country_code":"BE","type":"education","lineage":["https://openalex.org/I99464096"]}],"countries":["BE"],"is_corresponding":true,"raw_author_name":"Mathilda Froesel","raw_affiliation_strings":["Laboratory of Neuro- and Psychophysiology, Department of Neurosciences, KU Leuven Medical School; Leuven, 3000, Belgium; Leuven Brain Institute, KU Leuven; Leuven, 3000, Belgium;"],"raw_orcid":"https://orcid.org/0000-0003-1222-6317","affiliations":[{"raw_affiliation_string":"Laboratory of Neuro- and Psychophysiology, Department of Neurosciences, KU Leuven Medical School; Leuven, 3000, Belgium; Leuven Brain Institute, KU Leuven; Leuven, 3000, Belgium;","institution_ids":["https://openalex.org/I99464096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106038108","display_name":"Haiyan Wang","orcid":"https://orcid.org/0000-0003-1107-6679","observed_orcids":["https://orcid.org/0000-0003-1107-6679"]},"institutions":[{"id":"https://openalex.org/I99464096","display_name":"KU Leuven","ror":"https://ror.org/05f950310","country_code":"BE","type":"education","lineage":["https://openalex.org/I99464096"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Haiyan Wang","raw_affiliation_strings":["Dept. of Neurosciences, Lab. For Neuro-and Psychophysiology, KU Leuven, Leuven, Belgium;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Neurosciences, Lab. For Neuro-and Psychophysiology, KU Leuven, Leuven, Belgium;","institution_ids":["https://openalex.org/I99464096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019086139","display_name":"Wim Vanduffel","orcid":"https://orcid.org/0000-0002-9399-343X","observed_orcids":["https://orcid.org/0000-0002-9399-343X"]},"institutions":[{"id":"https://openalex.org/I99464096","display_name":"KU Leuven","ror":"https://ror.org/05f950310","country_code":"BE","type":"education","lineage":["https://openalex.org/I99464096"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Wim Vanduffel","raw_affiliation_strings":["Laboratory of Neuro- and Psychophysiology, Department of Neurosciences, KU Leuven Medical School; Leuven, 3000, Belgium; Leuven Brain Institute, KU Leuven; Leuven, 3000,;"],"raw_orcid":"https://orcid.org/0000-0002-9399-343X","affiliations":[{"raw_affiliation_string":"Laboratory of Neuro- and Psychophysiology, Department of Neurosciences, KU Leuven Medical School; Leuven, 3000, Belgium; Leuven Brain Institute, KU Leuven; Leuven, 3000,;","institution_ids":["https://openalex.org/I99464096"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5161461166","display_name":"Qi Zhu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Qi Zhu","raw_affiliation_strings":["University Paris Saclay"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Paris Saclay","institution_ids":["https://openalex.org/I277688954"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5050593009"],"corresponding_institution_ids":["https://openalex.org/I99464096"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11541","display_name":"Neuroendocrine regulation and behavior","score":0.9717000126838684,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11541","display_name":"Neuroendocrine regulation and behavior","score":0.9717000126838684,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10788","display_name":"Neuroscience and Music Perception","score":0.010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12032","display_name":"Multisensory perception and integration","score":0.006399999838322401,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[],"concepts":[{"id":"https://openalex.org/C2776176026","wikidata":"https://www.wikidata.org/wiki/Q169960","display_name":"Oxytocin","level":2,"score":0.8044000267982483},{"id":"https://openalex.org/C94487597","wikidata":"https://www.wikidata.org/wiki/Q11101","display_name":"Sensory system","level":2,"score":0.741599977016449},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.616599977016449},{"id":"https://openalex.org/C2776861996","wikidata":"https://www.wikidata.org/wiki/Q241849","display_name":"Sensory processing","level":3,"score":0.6137999892234802},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.5565999746322632},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5267999768257141},{"id":"https://openalex.org/C185263204","wikidata":"https://www.wikidata.org/wiki/Q1154774","display_name":"Electrophysiology","level":2,"score":0.4185999929904938},{"id":"https://openalex.org/C2777443451","wikidata":"https://www.wikidata.org/wiki/Q821413","display_name":"Auditory system","level":2,"score":0.4002000093460083},{"id":"https://openalex.org/C2780297895","wikidata":"https://www.wikidata.org/wiki/Q18676","display_name":"Auditory cortex","level":2,"score":0.39169999957084656},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.337799996137619},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.3314000070095062},{"id":"https://openalex.org/C111370547","wikidata":"https://www.wikidata.org/wiki/Q7451120","display_name":"Sensory cue","level":2,"score":0.30630001425743103},{"id":"https://openalex.org/C2988483714","wikidata":"https://www.wikidata.org/wiki/Q859031","display_name":"Auditory stimuli","level":3,"score":0.30140000581741333},{"id":"https://openalex.org/C46312422","wikidata":"https://www.wikidata.org/wiki/Q11024","display_name":"Communication","level":1,"score":0.2924000024795532},{"id":"https://openalex.org/C2781195155","wikidata":"https://www.wikidata.org/wiki/Q18680","display_name":"Prefrontal cortex","level":3,"score":0.2727000117301941},{"id":"https://openalex.org/C117838684","wikidata":"https://www.wikidata.org/wiki/Q533483","display_name":"Local field potential","level":2,"score":0.26510000228881836},{"id":"https://openalex.org/C2984127161","wikidata":"https://www.wikidata.org/wiki/Q969316","display_name":"Neural activity","level":2,"score":0.26190000772476196},{"id":"https://openalex.org/C118303440","wikidata":"https://www.wikidata.org/wiki/Q419968","display_name":"Neuropeptide","level":3,"score":0.2565000057220459}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.64898/2026.11.10.765620","doi":"https://doi.org/10.64898/2026.11.10.765620","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.11.10.765620","pdf_url":null,"source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.64898/2026.11.10.765620","doi":"https://doi.org/10.64898/2026.11.10.765620","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.11.10.765620","pdf_url":null,"source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"Oxytocin":[0,113],"shapes":[1],"social":[2,153],"perception,":[3],"yet":[4],"its":[5],"neural":[6],"effects":[7],"vary":[8],"substantially":[9],"across":[10,130],"experiments":[11],"and":[12,55,70,76,100,110,121,124,142],"clinical":[13],"trials":[14],"yield":[15],"inconsistent":[16],"results.":[17],"A":[18],"key":[19],"unresolved":[20],"question":[21],"is":[22],"whether":[23],"oxytocin":[24,49,62,137],"modulates":[25,138],"early":[26],"sensory":[27,35,139],"processing":[28],"in":[29,41,103,145],"primates":[30],"as":[31],"a":[32,104,146],"function":[33],"of":[34,107],"context.":[36],"Using":[37],"high-resolution":[38],"pharmacological":[39],"fMRI":[40],"two":[42],"awake":[43],"rhesus":[44],"macaques,":[45],"we":[46],"compared":[47],"systemic":[48],"with":[50],"saline":[51],"during":[52],"unimodal":[53,59],"auditory":[54,60,67,108],"audiovisual":[56,95],"tasks.":[57],"During":[58],"stimulation,":[61],"attenuated":[63],"sound-evoked":[64],"responses":[65,101,128],"throughout":[66],"core,":[68],"belt":[69,111],"associative":[71],"regions":[72],"for":[73],"both":[74],"vocal":[75],"non-vocal":[77],"sounds,":[78],"while":[79],"distributed":[80],"sound-category":[81],"information":[82],"remained":[83],"decodable.":[84],"In":[85],"contrast,":[86],"when":[87],"the":[88],"same":[89],"vocalizations":[90],"were":[91],"presented":[92],"within":[93],"an":[94],"task,":[96],"this":[97],"attenuation":[98],"disappeared":[99],"increased":[102],"restricted":[105],"set":[106],"core":[109],"regions.":[112],"also":[114],"reorganized":[115],"resting-state":[116],"coupling":[117],"among":[118],"auditory,":[119],"visual":[120],"prefrontal":[122],"systems":[123],"changed":[125],"how":[126],"evoked":[127],"covaried":[129],"runs.":[131],"Together,":[132],"these":[133],"findings":[134],"suggest":[135],"that":[136],"response":[140],"magnitude":[141],"inter-regional":[143],"coordination":[144],"context-dependent":[147],"manner":[148],"rather":[149],"than":[150],"uniformly":[151],"enhancing":[152],"signals.":[154]},"counts_by_year":[],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2026-11-12T00:00:00"}