{"id":"https://openalex.org/W7225829960","doi":"https://doi.org/10.3390/gels12111029","title":"Gamma Radiation-Assisted Synthesis of Xanthan Gum/Acrylamide Hydrogels for Drug Delivery","display_name":"Gamma Radiation-Assisted Synthesis of Xanthan Gum/Acrylamide Hydrogels for Drug Delivery","publication_year":2026,"publication_date":"2026-11-11","ids":{"openalex":"https://openalex.org/W7225829960","doi":"https://doi.org/10.3390/gels12111029"},"language":"en","primary_location":{"id":"doi:10.3390/gels12111029","doi":"https://doi.org/10.3390/gels12111029","is_oa":true,"landing_page_url":"https://doi.org/10.3390/gels12111029","pdf_url":null,"source":{"id":"https://openalex.org/S2737559645","display_name":"Gels","issn_l":"2310-2861","issn":["2310-2861"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gels","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/gels12111029","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090529432","display_name":"Carla Padilla","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I8961855","display_name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico","ror":"https://ror.org/01tmp8f25","country_code":"MX","type":"education","lineage":["https://openalex.org/I8961855"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Carla Padilla","raw_affiliation_strings":["Instituto de Ciencias Nucleares, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Av. Universidad #3000, Ciudad Universitaria S/N, Mexico City CP 04510, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto de Ciencias Nucleares, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Av. Universidad #3000, Ciudad Universitaria S/N, Mexico City CP 04510, Mexico","institution_ids":["https://openalex.org/I8961855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101606576","display_name":"Alejandra Ortega","orcid":"https://orcid.org/0000-0001-8973-901X","observed_orcids":["https://orcid.org/0000-0001-8973-901X"]},"institutions":[{"id":"https://openalex.org/I8961855","display_name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico","ror":"https://ror.org/01tmp8f25","country_code":"MX","type":"education","lineage":["https://openalex.org/I8961855"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Alejandra Ortega","raw_affiliation_strings":["Instituto de Ciencias Nucleares, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Av. Universidad #3000, Ciudad Universitaria S/N, Mexico City CP 04510, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto de Ciencias Nucleares, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Av. Universidad #3000, Ciudad Universitaria S/N, Mexico City CP 04510, Mexico","institution_ids":["https://openalex.org/I8961855"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030846848","display_name":"Guillermina Burillo","orcid":"https://orcid.org/0000-0001-8993-4923","observed_orcids":["https://orcid.org/0000-0001-8993-4923"]},"institutions":[{"id":"https://openalex.org/I8961855","display_name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico","ror":"https://ror.org/01tmp8f25","country_code":"MX","type":"education","lineage":["https://openalex.org/I8961855"]}],"countries":["MX"],"is_corresponding":true,"raw_author_name":"Guillermina Burillo","raw_affiliation_strings":["Instituto de Ciencias Nucleares, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Av. Universidad #3000, Ciudad Universitaria S/N, Mexico City CP 04510, Mexico"],"raw_orcid":"https://orcid.org/0000-0001-8993-4923","affiliations":[{"raw_affiliation_string":"Instituto de Ciencias Nucleares, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Av. Universidad #3000, Ciudad Universitaria S/N, Mexico City CP 04510, Mexico","institution_ids":["https://openalex.org/I8961855"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5030846848"],"corresponding_institution_ids":["https://openalex.org/I8961855"],"apc_list":{"value":2100,"currency":"CHF","value_usd":2534},"apc_paid":{"value":2100,"currency":"CHF","value_usd":2534},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"12","issue":"11","first_page":"1029","last_page":"1029"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12192","display_name":"Polysaccharides Composition and Applications","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12642","display_name":"Polymer-Based Agricultural Enhancements","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1102","display_name":"Agronomy and Crop Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[],"concepts":[{"id":"https://openalex.org/C108586683","wikidata":"https://www.wikidata.org/wiki/Q17164826","display_name":"Self-healing hydrogels","level":2,"score":0.9136000275611877},{"id":"https://openalex.org/C2778540859","wikidata":"https://www.wikidata.org/wiki/Q152234","display_name":"Swelling","level":2,"score":0.8238000273704529},{"id":"https://openalex.org/C2775937945","wikidata":"https://www.wikidata.org/wiki/Q222958","display_name":"Grafting","level":3,"score":0.7809000015258789},{"id":"https://openalex.org/C2779402116","wikidata":"https://www.wikidata.org/wiki/Q342939","display_name":"Acrylamide","level":4,"score":0.66839998960495},{"id":"https://openalex.org/C2779032678","wikidata":"https://www.wikidata.org/wiki/Q159683","display_name":"Citric acid","level":2,"score":0.6190000176429749},{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.604200005531311},{"id":"https://openalex.org/C2780100132","wikidata":"https://www.wikidata.org/wiki/Q410768","display_name":"Xanthan gum","level":3,"score":0.5546000003814697},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.499099999666214},{"id":"https://openalex.org/C188027245","wikidata":"https://www.wikidata.org/wiki/Q750446","display_name":"Polymer chemistry","level":1,"score":0.4799000024795532},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.46140000224113464},{"id":"https://openalex.org/C2779310008","wikidata":"https://www.wikidata.org/wiki/Q8578553","display_name":"Interpenetrating polymer network","level":3,"score":0.45730000734329224},{"id":"https://openalex.org/C168314062","wikidata":"https://www.wikidata.org/wiki/Q2550696","display_name":"Absorption of water","level":2,"score":0.42739999294281006},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.40529999136924744},{"id":"https://openalex.org/C6648577","wikidata":"https://www.wikidata.org/wiki/Q622669","display_name":"Porosity","level":2,"score":0.3736000061035156},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.3528999984264374},{"id":"https://openalex.org/C166940927","wikidata":"https://www.wikidata.org/wiki/Q178827","display_name":"Monomer","level":3,"score":0.33399999141693115},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.3244999945163727},{"id":"https://openalex.org/C125287762","wikidata":"https://www.wikidata.org/wiki/Q1758948","display_name":"Absorption (acoustics)","level":2,"score":0.2822999954223633},{"id":"https://openalex.org/C122302759","wikidata":"https://www.wikidata.org/wiki/Q2345087","display_name":"Fibroin","level":3,"score":0.27379998564720154},{"id":"https://openalex.org/C126201875","wikidata":"https://www.wikidata.org/wiki/Q2684948","display_name":"Nanorod","level":2,"score":0.2694999873638153},{"id":"https://openalex.org/C13245373","wikidata":"https://www.wikidata.org/wiki/Q3715494","display_name":"Drug carrier","level":3,"score":0.2563000023365021},{"id":"https://openalex.org/C3017806408","wikidata":"https://www.wikidata.org/wiki/Q92772955","display_name":"Gamma irradiation","level":3,"score":0.2547999918460846},{"id":"https://openalex.org/C100817775","wikidata":"https://www.wikidata.org/wiki/Q134219","display_name":"Polysaccharide","level":2,"score":0.25209999084472656}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.3390/gels12111029","doi":"https://doi.org/10.3390/gels12111029","is_oa":true,"landing_page_url":"https://doi.org/10.3390/gels12111029","pdf_url":null,"source":{"id":"https://openalex.org/S2737559645","display_name":"Gels","issn_l":"2310-2861","issn":["2310-2861"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gels","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.3390/gels12111029","doi":"https://doi.org/10.3390/gels12111029","is_oa":true,"landing_page_url":"https://doi.org/10.3390/gels12111029","pdf_url":null,"source":{"id":"https://openalex.org/S2737559645","display_name":"Gels","issn_l":"2310-2861","issn":["2310-2861"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gels","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":46,"referenced_works":["https://openalex.org/W1590149820","https://openalex.org/W1949665482","https://openalex.org/W1964308644","https://openalex.org/W1967963084","https://openalex.org/W1992933878","https://openalex.org/W2026509842","https://openalex.org/W2029308143","https://openalex.org/W2031662554","https://openalex.org/W2048884721","https://openalex.org/W2055822227","https://openalex.org/W2093902211","https://openalex.org/W2140588488","https://openalex.org/W2585330288","https://openalex.org/W2740324920","https://openalex.org/W2746140996","https://openalex.org/W2791099541","https://openalex.org/W2912659287","https://openalex.org/W2996895007","https://openalex.org/W3015717458","https://openalex.org/W3023208910","https://openalex.org/W3044434817","https://openalex.org/W3164079031","https://openalex.org/W4220742838","https://openalex.org/W4288075267","https://openalex.org/W4318054881","https://openalex.org/W4319310721","https://openalex.org/W4319756865","https://openalex.org/W4361004984","https://openalex.org/W4362699155","https://openalex.org/W4385358401","https://openalex.org/W4389152302","https://openalex.org/W4389614693","https://openalex.org/W4390363747","https://openalex.org/W4390615188","https://openalex.org/W4390977303","https://openalex.org/W4392157192","https://openalex.org/W4401976928","https://openalex.org/W4402965519","https://openalex.org/W4403109009","https://openalex.org/W4404360985","https://openalex.org/W4409660913","https://openalex.org/W4413119053","https://openalex.org/W4417024221","https://openalex.org/W7117715512","https://openalex.org/W7133524612","https://openalex.org/W7154189578"],"related_works":[],"abstract_inverted_index":{"Xanthan":[0],"gum":[1],"(XG)":[2],"and":[3,45,76,95,107,144],"acrylamide":[4],"(AAm)":[5],"hydrogels":[6,109],"were":[7,49,98],"synthesized":[8],"using":[9],"gamma":[10,57,82],"radiation.":[11,58],"The":[12,32,59,148],"novelty":[13],"lies":[14],"in":[15,52,84,120,189,195],"the":[16,41,46,85,115,121,133,160,164,176,190,196],"use":[17],"of":[18,43,63,87,92,135,159,169],"a":[19,36,53,111,136,167],"simple":[20],"methodology":[21],"to":[22,132],"obtain":[23],"two":[24],"different":[25],"architectures,":[26],"thereby":[27],"tailoring":[28],"their":[29],"physicochemical":[30],"properties.":[31,147],"first":[33],"system":[34,61],"is":[35],"comb-type":[37,149,197],"hydrogel":[38,198],"(net-AAm)-g-XG,":[39],"where":[40,69],"crosslinking":[42],"AAm":[44,78],"XG":[47,70,88],"grafting":[48,93,161],"carried":[50],"out":[51],"single":[54],"step":[55],"via":[56],"second":[60,137],"consists":[62],"an":[64],"interpenetrating":[65,122],"network":[66,123],"(IPN)":[67],"(net-XG)-inter-(net-AAm),":[68],"was":[71,79,118,187],"crosslinked":[72,80],"with":[73],"citric":[74],"acid":[75],"then":[77],"by":[81],"radiation":[83],"presence":[86,134],"gel.":[89],"Good":[90],"degrees":[91],"(60%)":[94],"interpenetration":[96,177],"(75%)":[97],"obtained":[99],"at":[100,155,171],"8":[101],"kGy":[102],"for":[103,182],"both":[104],"systems.":[105],"Comb-type":[106],"IPN":[108,165,191],"showed":[110,150],"porous":[112],"structure,":[113],"but":[114,185],"pore":[116],"size":[117],"smaller":[119],"because":[124],"this":[125],"architecture":[126],"has":[127],"less":[128],"internal":[129],"space":[130],"due":[131],"network.":[138],"Morphological":[139],"differences":[140],"affected":[141],"water":[142],"absorption":[143],"drug":[145],"loading/release":[146],"its":[151],"maximum":[152],"swelling":[153,168],"(900%)":[154],"24":[156],"h,":[157,173],"regardless":[158],"amount;":[162],"while":[163],"exhibited":[166],"400\u2013600%":[170],"3":[172],"depending":[174],"on":[175],"degree.":[178],"Both":[179],"systems":[180],"allowed":[181],"ciprofloxacin":[183],"loading,":[184],"release":[186],"faster":[188],"(100":[192],"min)":[193],"than":[194],"(300":[199],"min).":[200]},"counts_by_year":[],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2026-11-12T00:00:00"}