{"id":"https://openalex.org/W7225820841","doi":"https://doi.org/10.1097/js9.0000000000005743","title":"Real-world comparative effectiveness of neoadjuvant chemoimmunotherapy versus chemotherapy for locally advanced esophageal squamous cell carcinoma: a retrospective cohort study","display_name":"Real-world comparative effectiveness of neoadjuvant chemoimmunotherapy versus chemotherapy for locally advanced esophageal squamous cell carcinoma: a retrospective cohort study","publication_year":2026,"publication_date":"2026-11-11","ids":{"openalex":"https://openalex.org/W7225820841","doi":"https://doi.org/10.1097/js9.0000000000005743"},"language":"en","primary_location":{"id":"doi:10.1097/js9.0000000000005743","doi":"https://doi.org/10.1097/js9.0000000000005743","is_oa":true,"landing_page_url":"https://doi.org/10.1097/js9.0000000000005743","pdf_url":null,"source":{"id":"https://openalex.org/S67965910","display_name":"International Journal of Surgery","issn_l":"1743-9159","issn":["1743-9159","1743-9191"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-3","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Surgery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1097/js9.0000000000005743","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5146088394","display_name":"Yong Ao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":"CN","type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]},{"id":"https://openalex.org/I4405271975","display_name":"Guangdong Esophageal Cancer Research Institute","ror":"https://ror.org/03bx26w15","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4405271975"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yong Ao","raw_affiliation_strings":["Department of Thoracic Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China","Guangdong Esophageal Cancer Research Institute, Guangzhou, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Thoracic Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]},{"raw_affiliation_string":"Guangdong Esophageal Cancer Research Institute, Guangzhou, P. R. China","institution_ids":["https://openalex.org/I4405271975"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5158807364","display_name":"Changsen Leng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":"CN","type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]},{"id":"https://openalex.org/I4405271975","display_name":"Guangdong Esophageal Cancer Research Institute","ror":"https://ror.org/03bx26w15","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4405271975"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Changsen Leng","raw_affiliation_strings":["Department of Thoracic Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China","Guangdong Esophageal Cancer Research Institute, Guangzhou, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Thoracic Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]},{"raw_affiliation_string":"Guangdong Esophageal Cancer Research Institute, Guangzhou, P. R. China","institution_ids":["https://openalex.org/I4405271975"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5158836674","display_name":"Kongjia Luo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":"CN","type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]},{"id":"https://openalex.org/I4405271975","display_name":"Guangdong Esophageal Cancer Research Institute","ror":"https://ror.org/03bx26w15","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4405271975"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kongjia Luo","raw_affiliation_strings":["Department of Thoracic Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China","Guangdong Esophageal Cancer Research Institute, Guangzhou, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Thoracic Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]},{"raw_affiliation_string":"Guangdong Esophageal Cancer Research Institute, Guangzhou, P. R. China","institution_ids":["https://openalex.org/I4405271975"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5122782932","display_name":"Junying Chen","orcid":"https://orcid.org/0000-0001-7732-4319","observed_orcids":["https://orcid.org/0000-0001-7732-4319"]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":"CN","type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]},{"id":"https://openalex.org/I4405271975","display_name":"Guangdong Esophageal Cancer Research Institute","ror":"https://ror.org/03bx26w15","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4405271975"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Junying Chen","raw_affiliation_strings":["Department of Thoracic Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China","Guangdong Esophageal Cancer Research Institute, Guangzhou, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Thoracic Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]},{"raw_affiliation_string":"Guangdong Esophageal Cancer Research Institute, Guangzhou, P. R. China","institution_ids":["https://openalex.org/I4405271975"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133731974","display_name":"Lu Shao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lu Shao","raw_affiliation_strings":["School of Nursing, Sun Yat-sen University, Guangzhou, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Nursing, Sun Yat-sen University, Guangzhou, P. R. China","institution_ids":["https://openalex.org/I157773358"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160712332","display_name":"Qianwen Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":"CN","type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]},{"id":"https://openalex.org/I4405271975","display_name":"Guangdong Esophageal Cancer Research Institute","ror":"https://ror.org/03bx26w15","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4405271975"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qianwen Liu","raw_affiliation_strings":["Department of Thoracic Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China","Guangdong Esophageal Cancer Research Institute, Guangzhou, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Thoracic Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]},{"raw_affiliation_string":"Guangdong Esophageal Cancer Research Institute, Guangzhou, P. R. China","institution_ids":["https://openalex.org/I4405271975"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161492727","display_name":"Dawang Zhou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":"CN","type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]},{"id":"https://openalex.org/I4405271975","display_name":"Guangdong Esophageal Cancer Research Institute","ror":"https://ror.org/03bx26w15","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4405271975"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dawang Zhou","raw_affiliation_strings":["Department of Thoracic Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China","Guangdong Esophageal Cancer Research Institute, Guangzhou, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Thoracic Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]},{"raw_affiliation_string":"Guangdong Esophageal Cancer Research Institute, Guangzhou, P. R. China","institution_ids":["https://openalex.org/I4405271975"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161432689","display_name":"Yuhong Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":"CN","type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuhong Li","raw_affiliation_strings":["Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5124134485","display_name":"Fenghua Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":"CN","type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fenghua Wang","raw_affiliation_strings":["Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161431721","display_name":"Huiyan Luo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":"CN","type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huiyan Luo","raw_affiliation_strings":["Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161430631","display_name":"Xu Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":"CN","type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]},{"id":"https://openalex.org/I4405271975","display_name":"Guangdong Esophageal Cancer Research Institute","ror":"https://ror.org/03bx26w15","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4405271975"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xu Zhang","raw_affiliation_strings":["Department of Thoracic Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China","Guangdong Esophageal Cancer Research Institute, Guangzhou, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Thoracic Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]},{"raw_affiliation_string":"Guangdong Esophageal Cancer Research Institute, Guangzhou, P. R. China","institution_ids":["https://openalex.org/I4405271975"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074483535","display_name":"\u6768\u5f18","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":"CN","type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]},{"id":"https://openalex.org/I4405271975","display_name":"Guangdong Esophageal Cancer Research Institute","ror":"https://ror.org/03bx26w15","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4405271975"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hong Yang","raw_affiliation_strings":["Department of Thoracic Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China","Guangdong Esophageal Cancer Research Institute, Guangzhou, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Thoracic Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]},{"raw_affiliation_string":"Guangdong Esophageal Cancer Research Institute, Guangzhou, P. R. China","institution_ids":["https://openalex.org/I4405271975"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100723159","display_name":"Jianhua Fu","orcid":"https://orcid.org/0009-0002-6607-9068","observed_orcids":["https://orcid.org/0009-0002-6607-9068"]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":"CN","type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]},{"id":"https://openalex.org/I4405271975","display_name":"Guangdong Esophageal Cancer Research Institute","ror":"https://ror.org/03bx26w15","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4405271975"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianhua Fu","raw_affiliation_strings":["Department of Thoracic Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China","Guangdong Esophageal Cancer Research Institute, Guangzhou, P. R. China"],"raw_orcid":"https://orcid.org/0009-0002-6607-9068","affiliations":[{"raw_affiliation_string":"Department of Thoracic Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]},{"raw_affiliation_string":"Guangdong Esophageal Cancer Research Institute, Guangzhou, P. R. China","institution_ids":["https://openalex.org/I4405271975"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3450,"currency":"USD","value_usd":3450},"apc_paid":{"value":3450,"currency":"USD","value_usd":3450},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10619","display_name":"Esophageal Cancer Research and Treatment","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10619","display_name":"Esophageal Cancer Research and Treatment","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9642999768257141},{"id":"https://openalex.org/C2780790343","wikidata":"https://www.wikidata.org/wiki/Q5090610","display_name":"Chemoimmunotherapy","level":4,"score":0.9194999933242798},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6754000186920166},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.6514000296592712},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5972999930381775},{"id":"https://openalex.org/C2778292576","wikidata":"https://www.wikidata.org/wiki/Q6991934","display_name":"Neoadjuvant therapy","level":4,"score":0.5735999941825867},{"id":"https://openalex.org/C2777297899","wikidata":"https://www.wikidata.org/wiki/Q298191","display_name":"Esophagectomy","level":4,"score":0.5719000101089478},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.5712000131607056},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.4896000027656555},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.41190001368522644},{"id":"https://openalex.org/C2779742542","wikidata":"https://www.wikidata.org/wiki/Q372701","display_name":"Esophageal cancer","level":3,"score":0.40139999985694885},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.3262999951839447},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3239000141620636},{"id":"https://openalex.org/C2780824555","wikidata":"https://www.wikidata.org/wiki/Q1809305","display_name":"Lymphadenectomy","level":3,"score":0.32109999656677246},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.3208000063896179},{"id":"https://openalex.org/C2778203143","wikidata":"https://www.wikidata.org/wiki/Q6986146","display_name":"Nedaplatin","level":4,"score":0.3192000091075897},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.31189998984336853},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3075999915599823},{"id":"https://openalex.org/C207886595","wikidata":"https://www.wikidata.org/wiki/Q1456138","display_name":"Pathological","level":2,"score":0.3046000003814697},{"id":"https://openalex.org/C2994415158","wikidata":"https://www.wikidata.org/wiki/Q372701","display_name":"Esophageal squamous cell carcinoma","level":3,"score":0.3043000102043152},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.3025999963283539},{"id":"https://openalex.org/C3019096185","wikidata":"https://www.wikidata.org/wiki/Q1340863","display_name":"Complete response","level":3,"score":0.2937000095844269},{"id":"https://openalex.org/C2776283816","wikidata":"https://www.wikidata.org/wiki/Q332823","display_name":"Survival rate","level":2,"score":0.2831999957561493},{"id":"https://openalex.org/C2777819096","wikidata":"https://www.wikidata.org/wiki/Q173710","display_name":"Esophagus","level":2,"score":0.27149999141693115},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.26510000228881836}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1097/js9.0000000000005743","doi":"https://doi.org/10.1097/js9.0000000000005743","is_oa":true,"landing_page_url":"https://doi.org/10.1097/js9.0000000000005743","pdf_url":null,"source":{"id":"https://openalex.org/S67965910","display_name":"International Journal of Surgery","issn_l":"1743-9159","issn":["1743-9159","1743-9191"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-3","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Surgery","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1097/js9.0000000000005743","doi":"https://doi.org/10.1097/js9.0000000000005743","is_oa":true,"landing_page_url":"https://doi.org/10.1097/js9.0000000000005743","pdf_url":null,"source":{"id":"https://openalex.org/S67965910","display_name":"International Journal of Surgery","issn_l":"1743-9159","issn":["1743-9159","1743-9191"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-3","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Surgery","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W1922694287","https://openalex.org/W1966714873","https://openalex.org/W2096998881","https://openalex.org/W2155104309","https://openalex.org/W2291509448","https://openalex.org/W2735301415","https://openalex.org/W3148827278","https://openalex.org/W3173451714","https://openalex.org/W4220669277","https://openalex.org/W4229046570","https://openalex.org/W4285384887","https://openalex.org/W4288737780","https://openalex.org/W4303183116","https://openalex.org/W4309200663","https://openalex.org/W4391037813","https://openalex.org/W4396999988","https://openalex.org/W4399561523","https://openalex.org/W4400079367","https://openalex.org/W4400249061","https://openalex.org/W4403145509","https://openalex.org/W4403761388","https://openalex.org/W4407417141","https://openalex.org/W4408591457","https://openalex.org/W4411696687","https://openalex.org/W4415614294","https://openalex.org/W4415808637"],"related_works":[],"abstract_inverted_index":{"Background:":[0],"Neoadjuvant":[1],"chemoimmunotherapy":[2],"(NCIT)":[3],"has":[4],"shown":[5],"higher":[6,129],"pathologic":[7],"response":[8,132],"rates":[9,133,183,200],"than":[10,134],"neoadjuvant":[11,253],"chemotherapy":[12],"(NCT)":[13],"in":[14,50,186,192,242],"patients":[15,55,104,243],"with":[16,176,234,239,244],"locally":[17],"advanced":[18],"esophageal":[19],"squamous":[20],"cell":[21],"carcinoma":[22],"(LA-ESCC).":[23],"Recent":[24],"studies":[25],"have":[26],"reported":[27],"comparative":[28],"survival":[29,74,78,241],"outcomes,":[30,72],"but":[31],"evidence":[32],"from":[33,63],"extended":[34],"follow-up":[35,117],"remains":[36,258],"limited.":[37],"Methods:":[38],"This":[39],"retrospective":[40],"cohort":[41],"study":[42,101],"was":[43,118,237],"conducted":[44],"at":[45],"a":[46,251],"large":[47],"cancer":[48],"center":[49],"southern":[51],"China.":[52],"Consecutive":[53],"LA-ESCC":[54],"who":[56],"underwent":[57],"esophagectomy":[58],"following":[59],"NCT":[60,84,136,194],"or":[61],"NCIT":[62,86,110,125,146,188,208,236,249],"April":[64],"2012":[65],"to":[66],"February":[67],"2023":[68],"were":[69,80,184,201],"included.":[70],"Pathological":[71],"disease-free":[73],"(DFS),":[75],"and":[76,85,89,164,203,226],"overall":[77,216],"(OS)":[79],"compared":[81,175],"between":[82],"the":[83,124,135,187,193,197,207],"groups":[87],"before":[88],"after":[90],"applying":[91],"stabilized":[92],"inverse":[93],"probability":[94],"of":[95,215],"treatment":[96],"weighting":[97],"(IPTW).":[98],"Results:":[99],"The":[100,115,180],"included":[102],"478":[103],"(NCT":[105],"group,":[106,111,195],"n":[107,112],"=":[108,113,154,167],"230;":[109],"248).":[114],"median":[116],"45.6":[119],"months.":[120],"After":[121],"IPTW":[122],"adjustment,":[123],"group":[126,137,189,209],"exhibited":[127],"significantly":[128,148],"pathological":[130],"complete":[131],"(29.8%":[138],"vs.":[139,219,224,230],"9.5%,":[140],"P":[141,161,172],"<":[142,162,173],"0.001).":[143],"Patients":[144],"receiving":[145,178],"experienced":[147],"longer":[149],"OS":[150,182],"[hazard":[151],"ratio":[152],"(HR)":[153],"0.37;":[155],"95%":[156,169],"confidence":[157],"interval":[158],"(CI),":[159],"0.25\u20130.54;":[160],"0.001]":[163],"DFS":[165,199],"(HR":[166],"0.49;":[168],"CI,":[170],"0.36\u20130.68;":[171],"0.001)":[174],"those":[177],"NCT.":[179],"3-year":[181,198],"81.8%":[185],"versus":[190],"57.7%":[191],"while":[196],"69.3%":[202],"47.9%,":[204],"respectively.":[205],"Additionally,":[206],"had":[210],"lower":[211],"2-year":[212],"observed":[213],"proportions":[214],"recurrence":[217,222],"(11.3%":[218],"30.6%),":[220],"locoregional":[221],"(2.6%":[223],"8.7%),":[225],"distant":[227],"metastasis":[228],"(1.5%":[229],"8.7%).":[231],"Conclusions:":[232],"Compared":[233],"NCT,":[235],"associated":[238],"improved":[240],"LA-ESCC.":[245],"These":[246],"findings":[247],"support":[248],"as":[250],"promising":[252],"option,":[254],"although":[255],"prospective":[256],"validation":[257],"necessary.":[259]},"counts_by_year":[],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2026-11-12T00:00:00"}
