{"id":"https://openalex.org/W7225820030","doi":"https://doi.org/10.66789/tjcvd.2026.827","title":"Early C-reactive protein dynamics and 90-day functional outcome after complete reperfusion with mechanical thrombectomy","display_name":"Early C-reactive protein dynamics and 90-day functional outcome after complete reperfusion with mechanical thrombectomy","publication_year":2026,"publication_date":"2026-11-11","ids":{"openalex":"https://openalex.org/W7225820030","doi":"https://doi.org/10.66789/tjcvd.2026.827"},"language":"en","primary_location":{"id":"doi:10.66789/tjcvd.2026.827","doi":"https://doi.org/10.66789/tjcvd.2026.827","is_oa":true,"landing_page_url":"https://doi.org/10.66789/tjcvd.2026.827","pdf_url":null,"source":{"id":"https://openalex.org/S5407047893","display_name":"Turkish Journal of Cerebrovascular Diseases","issn_l":"1301-1375","issn":["1301-1375","2146-9113","3062-3707"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["tr-dizin"],"host_organization":"https://openalex.org/P4310318333","host_organization_name":"Turkish Society of Cerebrovascular Diseases","host_organization_lineage":["https://openalex.org/P4310318333"],"host_organization_lineage_names":["Turkish Society of Cerebrovascular Diseases"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Turkish Journal of Cerebrovascular Diseases","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.66789/tjcvd.2026.827","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023605687","display_name":"Utku Cenikli","orcid":"https://orcid.org/0000-0001-8433-5657","observed_orcids":["https://orcid.org/0000-0001-8433-5657"]},"institutions":[{"id":"https://openalex.org/I79946792","display_name":"Mu\u011fla University","ror":"https://ror.org/05n2cz176","country_code":"TR","type":"education","lineage":["https://openalex.org/I79946792"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Utku Cenikli","raw_affiliation_strings":["Department of Neurology, Faculty of Medicine, Mu\u011fla S\u0131tk\u0131 Ko\u00e7man University, Mu\u011fla, T\u00fcrkiye"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Faculty of Medicine, Mu\u011fla S\u0131tk\u0131 Ko\u00e7man University, Mu\u011fla, T\u00fcrkiye","institution_ids":["https://openalex.org/I79946792"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092386328","display_name":"\u0130nan \u00d6zdemir","orcid":"https://orcid.org/0000-0002-7510-4360","observed_orcids":["https://orcid.org/0000-0002-7510-4360"]},"institutions":[{"id":"https://openalex.org/I79946792","display_name":"Mu\u011fla University","ror":"https://ror.org/05n2cz176","country_code":"TR","type":"education","lineage":["https://openalex.org/I79946792"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"\u0130nan \u00d6zdemir","raw_affiliation_strings":["Department of Neurology, Faculty of Medicine, Mu\u011fla S\u0131tk\u0131 Ko\u00e7man University, Mu\u011fla, T\u00fcrkiye"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Faculty of Medicine, Mu\u011fla S\u0131tk\u0131 Ko\u00e7man University, Mu\u011fla, T\u00fcrkiye","institution_ids":["https://openalex.org/I79946792"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5093570082","display_name":"Osman Saraydar","orcid":"https://orcid.org/0009-0009-8056-3834","observed_orcids":["https://orcid.org/0009-0009-8056-3834"]},"institutions":[{"id":"https://openalex.org/I79946792","display_name":"Mu\u011fla University","ror":"https://ror.org/05n2cz176","country_code":"TR","type":"education","lineage":["https://openalex.org/I79946792"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Osman Saraydar","raw_affiliation_strings":["Department of Neurology, Faculty of Medicine, Mu\u011fla S\u0131tk\u0131 Ko\u00e7man University, Mu\u011fla, T\u00fcrkiye"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Faculty of Medicine, Mu\u011fla S\u0131tk\u0131 Ko\u00e7man University, Mu\u011fla, T\u00fcrkiye","institution_ids":["https://openalex.org/I79946792"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I79946792"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"32","issue":"Supplement 1","first_page":"20","last_page":"21"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11763","display_name":"Intracerebral and Subarachnoid Hemorrhage Research","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10420","display_name":"Intracranial Aneurysms: Treatment and Complications","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9761000275611877},{"id":"https://openalex.org/C2780931571","wikidata":"https://www.wikidata.org/wiki/Q568775","display_name":"Modified Rankin Scale","level":4,"score":0.8184000253677368},{"id":"https://openalex.org/C2779581417","wikidata":"https://www.wikidata.org/wiki/Q1931577","display_name":"Thrombolysis","level":3,"score":0.646399974822998},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5877000093460083},{"id":"https://openalex.org/C2781195455","wikidata":"https://www.wikidata.org/wiki/Q422766","display_name":"C-reactive protein","level":3,"score":0.49129998683929443},{"id":"https://openalex.org/C2779450755","wikidata":"https://www.wikidata.org/wiki/Q1209150","display_name":"Cerebral infarction","level":3,"score":0.47189998626708984},{"id":"https://openalex.org/C2780326628","wikidata":"https://www.wikidata.org/wiki/Q539795","display_name":"Angioplasty","level":2,"score":0.45809999108314514},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4422999918460846},{"id":"https://openalex.org/C2778583881","wikidata":"https://www.wikidata.org/wiki/Q1325542","display_name":"Stent","level":2,"score":0.41499999165534973},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.36480000615119934},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.352400004863739},{"id":"https://openalex.org/C139059822","wikidata":"https://www.wikidata.org/wiki/Q183951","display_name":"Balloon","level":2,"score":0.32670000195503235},{"id":"https://openalex.org/C2777798775","wikidata":"https://www.wikidata.org/wiki/Q207550","display_name":"Infarction","level":3,"score":0.3206000030040741},{"id":"https://openalex.org/C2778640784","wikidata":"https://www.wikidata.org/wiki/Q168002","display_name":"Ankle","level":2,"score":0.3122999966144562}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.66789/tjcvd.2026.827","doi":"https://doi.org/10.66789/tjcvd.2026.827","is_oa":true,"landing_page_url":"https://doi.org/10.66789/tjcvd.2026.827","pdf_url":null,"source":{"id":"https://openalex.org/S5407047893","display_name":"Turkish Journal of Cerebrovascular Diseases","issn_l":"1301-1375","issn":["1301-1375","2146-9113","3062-3707"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["tr-dizin"],"host_organization":"https://openalex.org/P4310318333","host_organization_name":"Turkish Society of Cerebrovascular Diseases","host_organization_lineage":["https://openalex.org/P4310318333"],"host_organization_lineage_names":["Turkish Society of Cerebrovascular Diseases"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Turkish Journal of Cerebrovascular Diseases","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.66789/tjcvd.2026.827","doi":"https://doi.org/10.66789/tjcvd.2026.827","is_oa":true,"landing_page_url":"https://doi.org/10.66789/tjcvd.2026.827","pdf_url":null,"source":{"id":"https://openalex.org/S5407047893","display_name":"Turkish Journal of Cerebrovascular Diseases","issn_l":"1301-1375","issn":["1301-1375","2146-9113","3062-3707"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["tr-dizin"],"host_organization":"https://openalex.org/P4310318333","host_organization_name":"Turkish Society of Cerebrovascular Diseases","host_organization_lineage":["https://openalex.org/P4310318333"],"host_organization_lineage_names":["Turkish Society of Cerebrovascular Diseases"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Turkish Journal of Cerebrovascular Diseases","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"Introduction:":[0],"The":[1,64,151,284],"inflammatory":[2],"response":[3],"after":[4,287],"mechanical":[5,53],"thrombectomy":[6,54],"may":[7],"influence":[8],"clinical":[9,372],"outcome.":[10],"This":[11],"study":[12],"evaluated":[13],"the":[14,17,127,140,148,185,195,238,246,270,288,304,320,331,355],"relationship":[15],"between":[16,55,153,319],"early":[18],"CRP":[19,35,99,143,156,202,233,311,351,362],"course":[20],"and":[21,33,58,97,105,132,157,166,181,194,213,242,302,330,336,359],"90-day":[22,112,367],"functional":[23],"outcome":[24,159,268,369],"in":[25,41,74,119,237,245,254,269,303,323],"patients":[26,50,68,134,187,221,290,322,340],"who":[27,51,69,135,341],"achieved":[28,70,190,342],"complete":[29,343],"reperfusion":[30,344],"with":[31,37,82,164,263,291,345],"aspiration,":[32],"compared":[34],"levels":[36],"those":[38],"of":[39,226,259,266,371],"cases":[40],"which":[42],"a":[43,85,111,121,257,325,348],"stent":[44,86,122,326,349],"retriever":[45,87,327],"was":[46,95,124,162,203,234,261,313,328],"used.Methods:":[47],"Consecutive":[48],"adult":[49],"underwent":[52,136],"April":[56],"2019":[57],"July":[59],"2026":[60],"were":[61,80,145,173,295],"screened":[62],"retrospectively.":[63],"main":[65,149,196],"analysis":[66,197,272],"included":[67],"final":[71],"modified":[72,113],"Thrombolysis":[73],"Cerebral":[75],"Infarction":[76],"(mTICI)":[77],"3":[78,107,142,155,192,218,232,361],"reperfusion,":[79,193],"treated":[81],"aspiration":[83,332,346],"without":[84,347],"or":[88,93,129],"Solumbra":[89],"(additional":[90],"extracranial/intracranial":[91],"angioplasty":[92],"stenting":[94],"allowed),":[96],"had":[98],"measurements":[100],"at":[101,206,228,315],"baseline,":[102,207],"day":[103,106,141,154,211,217,229,360],"1,":[104,212],"as":[108,110,126],"well":[109],"Rankin":[114],"Scale":[115],"(mRS)":[116],"score.":[117],"Patients":[118],"whom":[120,324],"retriever/Solumbra":[123],"used":[125,329],"first-line":[128],"rescue":[130],"technique,":[131],"two":[133],"decompressive":[137,179,305],"surgery":[138,306],"before":[139],"measurement,":[144],"excluded":[146,296],"from":[147],"analysis.":[150],"association":[152,285],"unfavorable":[158,267,368],"(mRS":[160],"3\u20136)":[161],"assessed":[163],"classical":[165],"Firth":[167,278],"penalized":[168],"logistic":[169],"regression.":[170],"Sensitivity":[171],"analyses":[172],"performed":[174],"for":[175,366],"symptomatic":[176,292],"intracranial":[177,293],"hemorrhage,":[178],"surgery,":[180],"additional":[182],"angioplasty/stenting.Results:":[183],"Of":[184],"177":[186],"screened,":[188],"65":[189],"mTICI":[191],"comprised":[198],"54":[199],"patients.":[200],"Median":[201],"4.47":[204],"mg/L":[205,209,215,236,244],"12.19":[208],"on":[210,216],"29.55":[214],"(P<0.001).":[219,250],"Forty-three":[220],"(79.6%)":[222],"reached":[223],"an":[224],"mRS":[225,239,247],"0\u20132":[227,240],"90.":[230],"Day":[231],"18.41":[235],"group":[241,249,333],"107.98":[243],"3\u20136":[248],"A":[251],"one-unit":[252],"increase":[253],"log2(CRP+1)":[255],"(roughly":[256],"doubling":[258],"CRP)":[260],"associated":[262],"increased":[264],"odds":[265],"adjusted":[271],"(aOR":[273],"2.18;":[274],"95%":[275,281,299],"CI":[276,282,300],"1.15\u20134.13;":[277],"aOR":[279],"1.87;":[280],"1.08\u20133.22).":[283],"persisted":[286],"five":[289],"hemorrhage":[294],"(OR":[297],"2.77;":[298],"1.23\u20136.24)":[301],"sensitivity":[307],"analyses.":[308],"No":[309],"significant":[310],"difference":[312],"found":[314],"any":[316],"time":[317],"point":[318],"six":[321],"(Table":[334],"1":[335],"Figure":[337],"1).Discussion/Conclusion:":[338],"In":[339],"retriever,":[350],"rose":[352],"markedly":[353],"over":[354],"first":[356],"three":[357],"days,":[358],"carried":[363],"prognostic":[364],"information":[365],"independent":[370],"variables.Keywords:":[373]},"counts_by_year":[],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2026-11-12T00:00:00"}