{"id":"https://openalex.org/W7225817528","doi":"https://doi.org/10.3389/fmicb.2026.1994598","title":"Long-read metagenomic characterization of the resistome and mobilome in heavy-metal-contaminated soils","display_name":"Long-read metagenomic characterization of the resistome and mobilome in heavy-metal-contaminated soils","publication_year":2026,"publication_date":"2026-11-11","ids":{"openalex":"https://openalex.org/W7225817528","doi":"https://doi.org/10.3389/fmicb.2026.1994598"},"language":"en","primary_location":{"id":"doi:10.3389/fmicb.2026.1994598","doi":"https://doi.org/10.3389/fmicb.2026.1994598","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fmicb.2026.1994598","pdf_url":null,"source":{"id":"https://openalex.org/S2484704948","display_name":"Frontiers in Microbiology","issn_l":"1664-302X","issn":["1664-302X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Microbiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3389/fmicb.2026.1994598","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5119307906","display_name":"Iskander Isgandarov","orcid":"https://orcid.org/0009-0001-4386-3303","observed_orcids":["https://orcid.org/0009-0001-4386-3303"]},"institutions":[{"id":"https://openalex.org/I4210099401","display_name":"Institute of Plant Biology and Biotechnology","ror":"https://ror.org/00s0yct57","country_code":"KZ","type":"facility","lineage":["https://openalex.org/I4210099401","https://openalex.org/I4401200292"]}],"countries":["KZ"],"is_corresponding":false,"raw_author_name":"Iskander Isgandarov","raw_affiliation_strings":["Laboratory of Breeding and Biotechnology, Institute of Plant Biology and Biotechnology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Breeding and Biotechnology, Institute of Plant Biology and Biotechnology","institution_ids":["https://openalex.org/I4210099401"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092690883","display_name":"\u0416\u0430\u043d\u0430\u0440 \u0410\u0431\u0438\u043b\u0434\u0430","orcid":"https://orcid.org/0000-0001-8505-5243","observed_orcids":["https://orcid.org/0000-0001-8505-5243"]},"institutions":[{"id":"https://openalex.org/I4210099401","display_name":"Institute of Plant Biology and Biotechnology","ror":"https://ror.org/00s0yct57","country_code":"KZ","type":"facility","lineage":["https://openalex.org/I4210099401","https://openalex.org/I4401200292"]},{"id":"https://openalex.org/I4210128817","display_name":"Kazakh National Agrarian Research University","ror":"https://ror.org/033cvvt68","country_code":"KZ","type":"education","lineage":["https://openalex.org/I4210128817"]}],"countries":["KZ"],"is_corresponding":false,"raw_author_name":"Zhanar Abilda","raw_affiliation_strings":["Faculty of Agrobiology, Kazakh National Agrarian Research University","Laboratory of Breeding and Biotechnology, Institute of Plant Biology and Biotechnology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Agrobiology, Kazakh National Agrarian Research University","institution_ids":["https://openalex.org/I4210128817"]},{"raw_affiliation_string":"Laboratory of Breeding and Biotechnology, Institute of Plant Biology and Biotechnology","institution_ids":["https://openalex.org/I4210099401"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028064039","display_name":"\u0414\u0438\u0430\u0441 \u0414\u0430\u0443\u0440\u043e\u0432","orcid":"https://orcid.org/0000-0003-3073-4577","observed_orcids":["https://orcid.org/0000-0003-3073-4577"]},"institutions":[{"id":"https://openalex.org/I4210099401","display_name":"Institute of Plant Biology and Biotechnology","ror":"https://ror.org/00s0yct57","country_code":"KZ","type":"facility","lineage":["https://openalex.org/I4210099401","https://openalex.org/I4401200292"]}],"countries":["KZ"],"is_corresponding":false,"raw_author_name":"Dias Daurov","raw_affiliation_strings":["Laboratory of Breeding and Biotechnology, Institute of Plant Biology and Biotechnology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Breeding and Biotechnology, Institute of Plant Biology and Biotechnology","institution_ids":["https://openalex.org/I4210099401"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031603369","display_name":"\u0417\u0430\u0433\u0438\u043f\u0430 \u0421\u0430\u043f\u0430\u0445\u043e\u0432\u0430","orcid":"https://orcid.org/0000-0002-8007-5066","observed_orcids":["https://orcid.org/0000-0002-8007-5066"]},"institutions":[{"id":"https://openalex.org/I4210099401","display_name":"Institute of Plant Biology and Biotechnology","ror":"https://ror.org/00s0yct57","country_code":"KZ","type":"facility","lineage":["https://openalex.org/I4210099401","https://openalex.org/I4401200292"]}],"countries":["KZ"],"is_corresponding":false,"raw_author_name":"Zagipa Sapakhova","raw_affiliation_strings":["Laboratory of Breeding and Biotechnology, Institute of Plant Biology and Biotechnology","Tanir Research Laboratory"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Breeding and Biotechnology, Institute of Plant Biology and Biotechnology","institution_ids":["https://openalex.org/I4210099401"]},{"raw_affiliation_string":"Tanir Research Laboratory","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092690884","display_name":"\u0420\u0430\u0445\u0438\u043c \u041a\u0430\u043d\u0430\u0442","orcid":"https://orcid.org/0009-0009-2418-5920","observed_orcids":["https://orcid.org/0009-0009-2418-5920"]},"institutions":[{"id":"https://openalex.org/I4210099401","display_name":"Institute of Plant Biology and Biotechnology","ror":"https://ror.org/00s0yct57","country_code":"KZ","type":"facility","lineage":["https://openalex.org/I4210099401","https://openalex.org/I4401200292"]}],"countries":["KZ"],"is_corresponding":false,"raw_author_name":"Rakhim Kanat","raw_affiliation_strings":["Laboratory of Breeding and Biotechnology, Institute of Plant Biology and Biotechnology","Tanir Research Laboratory"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Breeding and Biotechnology, Institute of Plant Biology and Biotechnology","institution_ids":["https://openalex.org/I4210099401"]},{"raw_affiliation_string":"Tanir Research Laboratory","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072443905","display_name":"\u041a\u0430\u0431\u044b\u043b \u0416\u0430\u043c\u0431\u0430\u043a\u0438\u043d","orcid":"https://orcid.org/0000-0001-5243-145X","observed_orcids":["https://orcid.org/0000-0001-5243-145X"]},"institutions":[{"id":"https://openalex.org/I4210099401","display_name":"Institute of Plant Biology and Biotechnology","ror":"https://ror.org/00s0yct57","country_code":"KZ","type":"facility","lineage":["https://openalex.org/I4210099401","https://openalex.org/I4401200292"]}],"countries":["KZ"],"is_corresponding":false,"raw_author_name":"Kabyl Zhambakin","raw_affiliation_strings":["Laboratory of Breeding and Biotechnology, Institute of Plant Biology and Biotechnology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Breeding and Biotechnology, Institute of Plant Biology and Biotechnology","institution_ids":["https://openalex.org/I4210099401"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085857135","display_name":"\u0410\u0439\u043d\u0430\u0448 \u0414\u0430\u0443\u0440\u043e\u0432\u0430","orcid":"https://orcid.org/0000-0001-7949-9112","observed_orcids":["https://orcid.org/0000-0001-7949-9112"]},"institutions":[{"id":"https://openalex.org/I4210099401","display_name":"Institute of Plant Biology and Biotechnology","ror":"https://ror.org/00s0yct57","country_code":"KZ","type":"facility","lineage":["https://openalex.org/I4210099401","https://openalex.org/I4401200292"]}],"countries":["KZ"],"is_corresponding":false,"raw_author_name":"Ainash Daurova","raw_affiliation_strings":["Laboratory of Breeding and Biotechnology, Institute of Plant Biology and Biotechnology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Breeding and Biotechnology, Institute of Plant Biology and Biotechnology","institution_ids":["https://openalex.org/I4210099401"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082895552","display_name":"Raushan Ramazanova","orcid":"https://orcid.org/0000-0002-2059-709X","observed_orcids":["https://orcid.org/0000-0002-2059-709X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Raushan Ramazanova","raw_affiliation_strings":["U.U. Uspanov Kazakh Research Institute of Soil Science and Agrochemistry"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"U.U. Uspanov Kazakh Research Institute of Soil Science and Agrochemistry","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5140305127","display_name":"Assem Vyrakhmanova","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Assem Vyrakhmanova","raw_affiliation_strings":["U.U. Uspanov Kazakh Research Institute of Soil Science and Agrochemistry"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"U.U. Uspanov Kazakh Research Institute of Soil Science and Agrochemistry","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161486334","display_name":"Yulia Tugunova","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210099401","display_name":"Institute of Plant Biology and Biotechnology","ror":"https://ror.org/00s0yct57","country_code":"KZ","type":"facility","lineage":["https://openalex.org/I4210099401","https://openalex.org/I4401200292"]}],"countries":["KZ"],"is_corresponding":false,"raw_author_name":"Yulia Tugunova","raw_affiliation_strings":["Laboratory of Breeding and Biotechnology, Institute of Plant Biology and Biotechnology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Breeding and Biotechnology, Institute of Plant Biology and Biotechnology","institution_ids":["https://openalex.org/I4210099401"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161449710","display_name":"Milana Altynbayeva","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210099401","display_name":"Institute of Plant Biology and Biotechnology","ror":"https://ror.org/00s0yct57","country_code":"KZ","type":"facility","lineage":["https://openalex.org/I4210099401","https://openalex.org/I4401200292"]}],"countries":["KZ"],"is_corresponding":false,"raw_author_name":"Milana Altynbayeva","raw_affiliation_strings":["Laboratory of Breeding and Biotechnology, Institute of Plant Biology and Biotechnology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Breeding and Biotechnology, Institute of Plant Biology and Biotechnology","institution_ids":["https://openalex.org/I4210099401"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020384884","display_name":"\u041c\u0430\u043b\u0438\u043a\u0430 \u0428\u0430\u043c\u0435\u043a\u043e\u0432\u0430","orcid":"https://orcid.org/0000-0002-8746-7484","observed_orcids":["https://orcid.org/0000-0002-8746-7484"]},"institutions":[{"id":"https://openalex.org/I4210099401","display_name":"Institute of Plant Biology and Biotechnology","ror":"https://ror.org/00s0yct57","country_code":"KZ","type":"facility","lineage":["https://openalex.org/I4210099401","https://openalex.org/I4401200292"]}],"countries":["KZ"],"is_corresponding":true,"raw_author_name":"Malika Shamekova","raw_affiliation_strings":["Laboratory of Breeding and Biotechnology, Institute of Plant Biology and Biotechnology","Tanir Research Laboratory"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Breeding and Biotechnology, Institute of Plant Biology and Biotechnology","institution_ids":["https://openalex.org/I4210099401"]},{"raw_affiliation_string":"Tanir Research Laboratory","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5020384884"],"corresponding_institution_ids":["https://openalex.org/I4210099401"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"17","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10419","display_name":"Pharmaceutical and Antibiotic Environmental Impacts","score":0.8711000084877014,"subfield":{"id":"https://openalex.org/subfields/2310","display_name":"Pollution"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10419","display_name":"Pharmaceutical and Antibiotic Environmental Impacts","score":0.8711000084877014,"subfield":{"id":"https://openalex.org/subfields/2310","display_name":"Pollution"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.1103999987244606,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10139","display_name":"Heavy metals in environment","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/2310","display_name":"Pollution"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[],"concepts":[{"id":"https://openalex.org/C2776666601","wikidata":"https://www.wikidata.org/wiki/Q3457855","display_name":"Resistome","level":5,"score":0.8891000151634216},{"id":"https://openalex.org/C15151743","wikidata":"https://www.wikidata.org/wiki/Q903778","display_name":"Metagenomics","level":3,"score":0.798799991607666},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.7484999895095825},{"id":"https://openalex.org/C59582021","wikidata":"https://www.wikidata.org/wiki/Q1128751","display_name":"Contig","level":4,"score":0.6807000041007996},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.578000009059906},{"id":"https://openalex.org/C22744801","wikidata":"https://www.wikidata.org/wiki/Q172778","display_name":"Plasmid","level":3,"score":0.5494999885559082},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5264999866485596},{"id":"https://openalex.org/C132533263","wikidata":"https://www.wikidata.org/wiki/Q2347362","display_name":"Mobile genetic elements","level":4,"score":0.4657999873161316},{"id":"https://openalex.org/C200082930","wikidata":"https://www.wikidata.org/wiki/Q22327148","display_name":"Efflux","level":2,"score":0.4611000120639801},{"id":"https://openalex.org/C126513998","wikidata":"https://www.wikidata.org/wiki/Q8973627","display_name":"Nanopore sequencing","level":4,"score":0.4357999861240387},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4196000099182129},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4034000039100647},{"id":"https://openalex.org/C12455157","wikidata":"https://www.wikidata.org/wiki/Q7835331","display_name":"Transposition (logic)","level":2,"score":0.4020000100135803},{"id":"https://openalex.org/C3742359","wikidata":"https://www.wikidata.org/wiki/Q4839988","display_name":"Bacterial genome size","level":4,"score":0.36469998955726624},{"id":"https://openalex.org/C92938381","wikidata":"https://www.wikidata.org/wiki/Q83185","display_name":"Horizontal gene transfer","level":4,"score":0.3513000011444092},{"id":"https://openalex.org/C94665300","wikidata":"https://www.wikidata.org/wiki/Q63391344","display_name":"Antibiotic resistance","level":3,"score":0.3255000114440918},{"id":"https://openalex.org/C24432333","wikidata":"https://www.wikidata.org/wiki/Q2068526","display_name":"Whole genome sequencing","level":4,"score":0.2971999943256378},{"id":"https://openalex.org/C193252679","wikidata":"https://www.wikidata.org/wiki/Q242125","display_name":"Phylogenetic tree","level":3,"score":0.2752000093460083},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.2680000066757202},{"id":"https://openalex.org/C105793898","wikidata":"https://www.wikidata.org/wiki/Q7810783","display_name":"Tn3 transposon","level":5,"score":0.2653000056743622},{"id":"https://openalex.org/C2777695942","wikidata":"https://www.wikidata.org/wiki/Q149075","display_name":"Firmicutes","level":4,"score":0.25870001316070557},{"id":"https://openalex.org/C172365310","wikidata":"https://www.wikidata.org/wiki/Q7554937","display_name":"Soil microbiology","level":3,"score":0.25130000710487366}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.3389/fmicb.2026.1994598","doi":"https://doi.org/10.3389/fmicb.2026.1994598","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fmicb.2026.1994598","pdf_url":null,"source":{"id":"https://openalex.org/S2484704948","display_name":"Frontiers in Microbiology","issn_l":"1664-302X","issn":["1664-302X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Microbiology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.3389/fmicb.2026.1994598","doi":"https://doi.org/10.3389/fmicb.2026.1994598","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fmicb.2026.1994598","pdf_url":null,"source":{"id":"https://openalex.org/S2484704948","display_name":"Frontiers in Microbiology","issn_l":"1664-302X","issn":["1664-302X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Microbiology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":91,"referenced_works":["https://openalex.org/W1963459864","https://openalex.org/W1964640602","https://openalex.org/W1972568665","https://openalex.org/W1975534363","https://openalex.org/W1977418673","https://openalex.org/W1982479612","https://openalex.org/W1992460001","https://openalex.org/W2001123674","https://openalex.org/W2088714921","https://openalex.org/W2108814012","https://openalex.org/W2139459279","https://openalex.org/W2143445148","https://openalex.org/W2144783616","https://openalex.org/W2159432254","https://openalex.org/W2174481467","https://openalex.org/W2180695509","https://openalex.org/W2267357833","https://openalex.org/W2287163985","https://openalex.org/W2400652119","https://openalex.org/W2403054321","https://openalex.org/W2555699634","https://openalex.org/W2562864277","https://openalex.org/W2563315795","https://openalex.org/W2761178674","https://openalex.org/W2771499133","https://openalex.org/W2788264146","https://openalex.org/W2804902389","https://openalex.org/W2885680427","https://openalex.org/W2889713700","https://openalex.org/W2892316142","https://openalex.org/W2894347729","https://openalex.org/W2902569018","https://openalex.org/W2903347362","https://openalex.org/W2919629449","https://openalex.org/W2937378659","https://openalex.org/W2952926828","https://openalex.org/W2964551398","https://openalex.org/W2969866294","https://openalex.org/W2970367351","https://openalex.org/W2984113873","https://openalex.org/W3010507168","https://openalex.org/W3022703210","https://openalex.org/W3084100763","https://openalex.org/W3090089243","https://openalex.org/W3091126751","https://openalex.org/W3098103638","https://openalex.org/W3111851953","https://openalex.org/W3132431828","https://openalex.org/W3187959711","https://openalex.org/W3195853335","https://openalex.org/W3210890336","https://openalex.org/W4200185813","https://openalex.org/W4206459879","https://openalex.org/W4220942143","https://openalex.org/W4221137570","https://openalex.org/W4286435954","https://openalex.org/W4292574940","https://openalex.org/W4306871314","https://openalex.org/W4307047046","https://openalex.org/W4318040960","https://openalex.org/W4320913358","https://openalex.org/W4360601318","https://openalex.org/W4377087712","https://openalex.org/W4377823043","https://openalex.org/W4390582429","https://openalex.org/W4393380881","https://openalex.org/W4396577096","https://openalex.org/W4399729436","https://openalex.org/W4399873157","https://openalex.org/W4400000575","https://openalex.org/W4400955829","https://openalex.org/W4403395756","https://openalex.org/W4408040746","https://openalex.org/W4409273886","https://openalex.org/W4409530112","https://openalex.org/W4411340185","https://openalex.org/W4412583593","https://openalex.org/W4413992167","https://openalex.org/W4414222406","https://openalex.org/W4414267456","https://openalex.org/W4414382985","https://openalex.org/W4415695233","https://openalex.org/W7126073244","https://openalex.org/W7126174005","https://openalex.org/W7139090513","https://openalex.org/W7140082984","https://openalex.org/W7155018181","https://openalex.org/W7160486769","https://openalex.org/W7162298144","https://openalex.org/W7167806436","https://openalex.org/W7203674496"],"related_works":[],"abstract_inverted_index":{"Introduction":[0],"Heavy-metal":[1],"contamination":[2],"is":[3],"widely":[4],"proposed":[5],"to":[6,46,73,172,218,228,257],"co-select":[7],"for":[8,25,214],"antibiotic":[9],"resistance":[10,206,272],"by":[11,71,119],"placing":[12],"metal-":[13],"and":[14,54,63,82,92,117,130,138,190,223,235,244],"antibiotic-resistance":[15,137,252],"genes":[16,84,216],"on":[17,29,34,176],"the":[18,23,50,88,146,183,186,219,282],"same":[19],"mobile":[20],"elements,":[21],"yet":[22],"evidence":[24,292],"this":[26,133],"rests":[27],"largely":[28],"short-read":[30],"co-occurrence":[31,286],"rather":[32],"than":[33],"direct":[35,276],"observation":[36],"of":[37,57,76,101,110,193,293],"physical":[38,294],"linkage.":[39,295],"Methods":[40],"We":[41],"applied":[42],"Nanopore":[43],"long-read":[44],"metagenomics":[45],"four":[47,154],"soils":[48,266],"from":[49],"Ridder":[51],"polymetallic":[52],"mining":[53],"metallurgical":[55],"district":[56],"East":[58],"Kazakhstan,":[59],"where":[60],"zinc,":[61],"cadmium":[62],"lead":[64],"exceed":[65],"a":[66,113,162,166,224,239,245,269],"single":[67,177],"local":[68],"reference":[69],"site":[70],"up":[72],"two":[74,102,147],"orders":[75],"magnitude.":[77],"Physical":[78],"linkage":[79,278],"between":[80],"antibiotic-":[81],"metal-resistance":[83,140],"was":[85,170,179,279,301],"tested":[86],"at":[87],"contig,":[89],"read,":[90],"genome":[91,184,255],"community":[93],"levels":[94],"against":[95,158],"chance":[96],"expectation.":[97],"Results":[98],"Ensemble":[99],"binning":[100],"complementary":[103],"assemblies":[104],"produced":[105],"261":[106],"metagenome-assembled":[107],"genomes,":[108],"97%":[109],"them":[111],"lacking":[112],"GTDB":[114],"species":[115],"assignment":[116],"dominated":[118],"Actinomycetota,":[120],"together":[121],"with":[122],"73":[123],"closed":[124],"circular":[125],"elements":[126],"including":[127],"complete":[128,240],"phages":[129],"plasmids.":[131],"Screening":[132],"catalogue":[134,173,220],"recovered":[135],"991":[136],"395":[139],"loci.":[141],"In":[142],"these":[143],"metal-enriched":[144],"soils,":[145],"classes":[148,187],"were":[149,188,212],"rarely":[150],"physically":[151],"linked.":[152],"Only":[153],"contigs":[155,208],"carried":[156,204],"both,":[157],"28.9":[159],"expected":[160],"under":[161],"degree-preserving":[163],"null":[164],"model,":[165],"0.14-fold":[167],"depletion":[168],"that":[169],"robust":[171],"thresholds;":[174],"co-carriage":[175],"reads":[178],"likewise":[180],"rare.":[181],"At":[182],"level":[185],"independent,":[189],"in":[191,281],"22":[192],"24":[194],"dual-carrier":[195],"genomes":[196],"they":[197],"occupied":[198],"different":[199],"contigs.":[200],"The":[201],"mobilome":[202],"nonetheless":[203],"metal":[205,215],"preferentially:":[207],"called":[209],"as":[210,291],"plasmids":[211],"enriched":[213],"relative":[217],"base":[221],"rate,":[222],"142-kb":[225],"plasmid":[226],"predicted":[227],"be":[229,289],"conjugative":[230],"encoded":[231],"copper,":[232],"cadmium/zinc,":[233],"mercury":[234],"silver":[236],"efflux":[237],"systems,":[238],"type-IV":[241],"secretion":[242],"system":[243],"CBASS":[246],"anti-phage":[247],"defense":[248],"system,":[249],"but":[250,274],"no":[251,275],"gene.":[253],"No":[254],"belonged":[256],"an":[258],"ESKAPE":[259],"or":[260,299],"WHO-priority":[261],"pathogen":[262],"genus.":[263],"Discussion":[264],"These":[265],"are":[267],"therefore":[268],"large":[270],"environmental":[271],"reservoir,":[273],"clinical-risk":[277],"demonstrated":[280],"present":[283],"dataset.":[284],"Community":[285],"should":[287],"not":[288,302],"read":[290],"Co-selection":[296],"through":[297],"cross-resistance":[298],"co-regulation":[300],"excluded.":[303]},"counts_by_year":[],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2026-11-12T00:00:00"}
