{"id":"https://openalex.org/W7225817371","doi":"https://doi.org/10.1002/adhm.71962","title":"A Novel 3D Model Co\u2010Culturing Breast Cancer Cells in Direct Contact with Patient\u2010Derived Mature Adipocytes Demonstrates Cell\u2010Type Specific Alterations in Phenotype and Chemosensitivity","display_name":"A Novel 3D Model Co\u2010Culturing Breast Cancer Cells in Direct Contact with Patient\u2010Derived Mature Adipocytes Demonstrates Cell\u2010Type Specific Alterations in Phenotype and Chemosensitivity","publication_year":2026,"publication_date":"2026-11-11","ids":{"openalex":"https://openalex.org/W7225817371","doi":"https://doi.org/10.1002/adhm.71962","pmid":"https://pubmed.ncbi.nlm.nih.gov/43012449"},"language":"en","primary_location":{"id":"doi:10.1002/adhm.71962","doi":"https://doi.org/10.1002/adhm.71962","is_oa":true,"landing_page_url":"https://doi.org/10.1002/adhm.71962","pdf_url":null,"source":{"id":"https://openalex.org/S2500736452","display_name":"Advanced Healthcare Materials","issn_l":"2192-2640","issn":["2192-2640","2192-2659"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced Healthcare Materials","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1002/adhm.71962","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5104244921","display_name":"Jessika Wise","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Jessika A. Wise","raw_affiliation_strings":["Christchurch Regenerative Medicine and Tissue Engineering Department of Orthopaedic Surgery and Musculoskeletal Medicine University of Otago Christchurch  Christchurch New Zealand","Mackenzie Cancer Research Group Department of Pathology & Molecular Medicine University of Otago Christchurch Christchurch New Zealand"],"raw_orcid":"https://orcid.org/0000-0002-0678-3777","affiliations":[{"raw_affiliation_string":"Christchurch Regenerative Medicine and Tissue Engineering Department of Orthopaedic Surgery and Musculoskeletal Medicine University of Otago Christchurch  Christchurch New Zealand","institution_ids":["https://openalex.org/I80281795"]},{"raw_affiliation_string":"Mackenzie Cancer Research Group Department of Pathology & Molecular Medicine University of Otago Christchurch Christchurch New Zealand","institution_ids":["https://openalex.org/I80281795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057750122","display_name":"Margaret J. Currie","orcid":"https://orcid.org/0000-0002-9788-8098","observed_orcids":["https://orcid.org/0000-0002-9788-8098"]},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Margaret J. Currie","raw_affiliation_strings":["Mackenzie Cancer Research Group Department of Pathology & Molecular Medicine University of Otago Christchurch Christchurch New Zealand"],"raw_orcid":"https://orcid.org/0000-0002-9788-8098","affiliations":[{"raw_affiliation_string":"Mackenzie Cancer Research Group Department of Pathology & Molecular Medicine University of Otago Christchurch Christchurch New Zealand","institution_ids":["https://openalex.org/I80281795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109585311","display_name":"Helen R. Morrin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Helen R. Morrin","raw_affiliation_strings":["He Taonga Tapu Cancer Society Tissue Bank University of Otago Christchurch  Christchurch New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"He Taonga Tapu Cancer Society Tissue Bank University of Otago Christchurch  Christchurch New Zealand","institution_ids":["https://openalex.org/I80281795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077715463","display_name":"Gretel S. Major","orcid":"https://orcid.org/0000-0002-4275-4199","observed_orcids":["https://orcid.org/0000-0002-4275-4199"]},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Gretel S. Major","raw_affiliation_strings":["Christchurch Regenerative Medicine and Tissue Engineering Department of Orthopaedic Surgery and Musculoskeletal Medicine University of Otago Christchurch  Christchurch New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Christchurch Regenerative Medicine and Tissue Engineering Department of Orthopaedic Surgery and Musculoskeletal Medicine University of Otago Christchurch  Christchurch New Zealand","institution_ids":["https://openalex.org/I80281795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088892854","display_name":"Tim B. F. Woodfield","orcid":"https://orcid.org/0000-0002-5428-7575","observed_orcids":["https://orcid.org/0000-0002-5428-7575"]},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Tim B. F. Woodfield","raw_affiliation_strings":["Christchurch Regenerative Medicine and Tissue Engineering Department of Orthopaedic Surgery and Musculoskeletal Medicine University of Otago Christchurch  Christchurch New Zealand"],"raw_orcid":"https://orcid.org/0000-0002-5428-7575","affiliations":[{"raw_affiliation_string":"Christchurch Regenerative Medicine and Tissue Engineering Department of Orthopaedic Surgery and Musculoskeletal Medicine University of Otago Christchurch  Christchurch New Zealand","institution_ids":["https://openalex.org/I80281795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015866577","display_name":"Khoon S. Lim","orcid":"https://orcid.org/0000-0002-2486-196X","observed_orcids":["https://orcid.org/0000-0002-2486-196X"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Khoon S. Lim","raw_affiliation_strings":["Light\u2010Activated Biomaterials Group School of Medical Sciences University of Sydney Sydney NSW Australia"],"raw_orcid":"https://orcid.org/0000-0002-2486-196X","affiliations":[{"raw_affiliation_string":"Light\u2010Activated Biomaterials Group School of Medical Sciences University of Sydney Sydney NSW Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017804574","display_name":"Elisabeth Phillips","orcid":"https://orcid.org/0000-0002-9048-367X","observed_orcids":["https://orcid.org/0000-0002-9048-367X"]},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":true,"raw_author_name":"Elisabeth Phillips","raw_affiliation_strings":["Mackenzie Cancer Research Group Department of Pathology & Molecular Medicine University of Otago Christchurch Christchurch New Zealand"],"raw_orcid":"https://orcid.org/0000-0002-9048-367X","affiliations":[{"raw_affiliation_string":"Mackenzie Cancer Research Group Department of Pathology & Molecular Medicine University of Otago Christchurch Christchurch New Zealand","institution_ids":["https://openalex.org/I80281795"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5015866577","https://openalex.org/A5017804574"],"corresponding_institution_ids":["https://openalex.org/I129604602","https://openalex.org/I80281795"],"apc_list":{"value":4880,"currency":"USD","value_usd":4880},"apc_paid":{"value":4880,"currency":"USD","value_usd":4880},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.4643999934196472,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.4643999934196472,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12465","display_name":"Cancer, Lipids, and Metabolism","score":0.2502000033855438,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer","score":0.0697999969124794,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[],"concepts":[{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.7480999827384949},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.6435999870300293},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.6240000128746033},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.5722000002861023},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4830000102519989},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.4828000068664551},{"id":"https://openalex.org/C2776107976","wikidata":"https://www.wikidata.org/wiki/Q1786433","display_name":"Tumor microenvironment","level":3,"score":0.4487999975681305},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.44760000705718994},{"id":"https://openalex.org/C2776175234","wikidata":"https://www.wikidata.org/wiki/Q357519","display_name":"Adipocyte","level":3,"score":0.3993000090122223},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.38940000534057617},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.38359999656677246},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.37130001187324524},{"id":"https://openalex.org/C76419328","wikidata":"https://www.wikidata.org/wiki/Q74419","display_name":"Epithelial\u2013mesenchymal transition","level":4,"score":0.36959999799728394},{"id":"https://openalex.org/C122927707","wikidata":"https://www.wikidata.org/wiki/Q2824461","display_name":"Adipogenesis","level":3,"score":0.35830000042915344},{"id":"https://openalex.org/C109541995","wikidata":"https://www.wikidata.org/wiki/Q1881253","display_name":"MCF-7","level":5,"score":0.3379000127315521},{"id":"https://openalex.org/C39567582","wikidata":"https://www.wikidata.org/wiki/Q415624","display_name":"Perilipin","level":4,"score":0.3357999920845032},{"id":"https://openalex.org/C2780427987","wikidata":"https://www.wikidata.org/wiki/Q172341","display_name":"Ovarian cancer","level":3,"score":0.3059000074863434},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.30090001225471497},{"id":"https://openalex.org/C2909706936","wikidata":"https://www.wikidata.org/wiki/Q42417562","display_name":"Cancer-Associated Fibroblasts","level":4,"score":0.29319998621940613},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.2897000014781952},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.2831000089645386},{"id":"https://openalex.org/C118646709","wikidata":"https://www.wikidata.org/wiki/Q1657620","display_name":"CA15-3","level":4,"score":0.2793000042438507},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.27480000257492065},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.27070000767707825},{"id":"https://openalex.org/C2777292972","wikidata":"https://www.wikidata.org/wiki/Q423762","display_name":"Paclitaxel","level":3,"score":0.25850000977516174},{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.25099998712539673}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1002/adhm.71962","doi":"https://doi.org/10.1002/adhm.71962","is_oa":true,"landing_page_url":"https://doi.org/10.1002/adhm.71962","pdf_url":null,"source":{"id":"https://openalex.org/S2500736452","display_name":"Advanced Healthcare Materials","issn_l":"2192-2640","issn":["2192-2640","2192-2659"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced Healthcare Materials","raw_type":"journal-article"},{"id":"pmid:43012449","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/43012449","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced healthcare materials","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1002/adhm.71962","doi":"https://doi.org/10.1002/adhm.71962","is_oa":true,"landing_page_url":"https://doi.org/10.1002/adhm.71962","pdf_url":null,"source":{"id":"https://openalex.org/S2500736452","display_name":"Advanced Healthcare Materials","issn_l":"2192-2640","issn":["2192-2640","2192-2659"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced Healthcare Materials","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":81,"referenced_works":["https://openalex.org/W1120477740","https://openalex.org/W1506915739","https://openalex.org/W1869629480","https://openalex.org/W1919415219","https://openalex.org/W1955273596","https://openalex.org/W1964796703","https://openalex.org/W1967193940","https://openalex.org/W1974258861","https://openalex.org/W1983129031","https://openalex.org/W1986531666","https://openalex.org/W1997508706","https://openalex.org/W2005237823","https://openalex.org/W2012142451","https://openalex.org/W2017703699","https://openalex.org/W2023430066","https://openalex.org/W2023667904","https://openalex.org/W2031832448","https://openalex.org/W2032972527","https://openalex.org/W2043358786","https://openalex.org/W2043741624","https://openalex.org/W2051920559","https://openalex.org/W2053654414","https://openalex.org/W2055037957","https://openalex.org/W2056554708","https://openalex.org/W2071027495","https://openalex.org/W2071359790","https://openalex.org/W2078502914","https://openalex.org/W2091262660","https://openalex.org/W2095346591","https://openalex.org/W2100530166","https://openalex.org/W2108064025","https://openalex.org/W2115226530","https://openalex.org/W2120428737","https://openalex.org/W2123753226","https://openalex.org/W2144411343","https://openalex.org/W2146727045","https://openalex.org/W2154223976","https://openalex.org/W2158805869","https://openalex.org/W2161204617","https://openalex.org/W2167279371","https://openalex.org/W2171344824","https://openalex.org/W2172359919","https://openalex.org/W2301845707","https://openalex.org/W2337371518","https://openalex.org/W2395956309","https://openalex.org/W2491221858","https://openalex.org/W2573612572","https://openalex.org/W2584613980","https://openalex.org/W2586986838","https://openalex.org/W2589120174","https://openalex.org/W2752135877","https://openalex.org/W2766290664","https://openalex.org/W2789941734","https://openalex.org/W2795178600","https://openalex.org/W2797644116","https://openalex.org/W2804423755","https://openalex.org/W2805456840","https://openalex.org/W2806229604","https://openalex.org/W2883462871","https://openalex.org/W2885824319","https://openalex.org/W2901969242","https://openalex.org/W2911497803","https://openalex.org/W2942057572","https://openalex.org/W2949636451","https://openalex.org/W2961052208","https://openalex.org/W2965087682","https://openalex.org/W2966077125","https://openalex.org/W2970512524","https://openalex.org/W2971653317","https://openalex.org/W2972584423","https://openalex.org/W2976826808","https://openalex.org/W2980131068","https://openalex.org/W2996341812","https://openalex.org/W3006550293","https://openalex.org/W3016427456","https://openalex.org/W3044605555","https://openalex.org/W3087075141","https://openalex.org/W3116392492","https://openalex.org/W4249232487","https://openalex.org/W4353060305","https://openalex.org/W7130308524"],"related_works":[],"abstract_inverted_index":{"Mature":[0],"adipocytes":[1,22,74,98,166],"within":[2],"the":[3,15,50],"breast":[4,19,73,76,93,125,160],"tumour":[5,35],"microenvironment":[6],"contribute":[7],"a":[8,139,155],"significant":[9],"role":[10],"in":[11,54,63],"malignant":[12,177],"progression.":[13,178],"At":[14],"invasive":[16],"front":[17],"of":[18,52,101,131],"tumours,":[20],"mature":[21,42,72,97,165],"undergo":[23],"morphological":[24],"and":[25,28,37,75,106,113,135,167,176],"phenotypic":[26],"changes":[27],"may":[29],"provide":[30],"metabolic":[31],"support":[32],"to":[33,80,142,158],"fuel":[34],"growth":[36],"spread.":[38],"However,":[39],"investigations":[40],"into":[41],"adipocyte-breast":[43],"cancer":[44,77,94,126,161,168],"interactions":[45,84,163,171],"have":[46],"been":[47],"limited":[48],"by":[49,151],"lack":[51],"suitable":[53],"vitro":[55,64],"models.":[56],"Here,":[57],"we":[58],"developed":[59,150],"an":[60],"innovative":[61],"3D":[62,147],"co-culture":[65,89,148],"system":[66],"allowing":[67],"direct":[68,146],"contact":[69],"between":[70,164],"patient-derived":[71],"cell":[78],"lines,":[79],"systematically":[81],"examine":[82],"cell-cell":[83],"over":[85],"21":[86],"days.":[87],"In":[88,120],"with":[90,109,138,173],"triple":[91],"negative":[92],"cells":[95,127],"(MDA-MB-231),":[96],"exhibited":[99],"loss":[100],"Perilipin":[102],"1":[103],"(PLIN1)":[104],"expression":[105,130],"were":[107],"associated":[108,172],"reduced":[110],"chemotherapy":[111,174],"responsiveness":[112,175],"increased":[114,129],"Major":[115],"Vault":[116],"Protein":[117],"(MVP)":[118],"abundance.":[119],"contrast,":[121],"Luminal":[122],"A":[123],"(MCF7)":[124],"displayed":[128],"mesenchymal":[132,143],"markers":[133],"(N-cadherin":[134],"Vimentin),":[136],"consistent":[137],"partial":[140],"epithelial":[141],"transition.":[144],"The":[145],"model":[149],"this":[152],"work":[153],"provides":[154],"novel":[156],"platform":[157],"study":[159],"subtype-specific":[162],"cells,":[169],"revealing":[170]},"counts_by_year":[],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2026-11-12T00:00:00"}
