{"id":"https://openalex.org/W7225809234","doi":"https://doi.org/10.70164/jmbr.v3i6.1384","title":"Comparative effectiveness of interventions for mental health during pregnancy: a systematic review and network meta-analysis","display_name":"Comparative effectiveness of interventions for mental health during pregnancy: a systematic review and network meta-analysis","publication_year":2026,"publication_date":"2026-11-11","ids":{"openalex":"https://openalex.org/W7225809234","doi":"https://doi.org/10.70164/jmbr.v3i6.1384"},"language":"en","primary_location":{"id":"doi:10.70164/jmbr.v3i6.1384","doi":"https://doi.org/10.70164/jmbr.v3i6.1384","is_oa":true,"landing_page_url":"https://doi.org/10.70164/jmbr.v3i6.1384","pdf_url":null,"source":{"id":"https://openalex.org/S4404677169","display_name":"Journal of Medical and Biosciences Research.","issn_l":"2966-1668","issn":["2966-1668"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4404677168","host_organization_name":"Nilton Lins University","host_organization_lineage":["https://openalex.org/P4404677168"],"host_organization_lineage_names":["Nilton Lins University"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medical and Biosciences Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.70164/jmbr.v3i6.1384","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5152280587","display_name":"Habtamu Fekadu Andeta","orcid":"https://orcid.org/0009-0003-5270-6902","observed_orcids":["https://orcid.org/0009-0003-5270-6902"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Habtamu Fekadu Andeta","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0003-5270-6902","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5152280587"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"3","issue":"6","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10786","display_name":"Maternal Mental Health During Pregnancy and Postpartum","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10786","display_name":"Maternal Mental Health During Pregnancy and Postpartum","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12715","display_name":"Pregnancy-related medical research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12741","display_name":"Maternal and Neonatal Healthcare","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[],"concepts":[{"id":"https://openalex.org/C27415008","wikidata":"https://www.wikidata.org/wiki/Q7256382","display_name":"Psychological intervention","level":2,"score":0.7633000016212463},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7519999742507935},{"id":"https://openalex.org/C134362201","wikidata":"https://www.wikidata.org/wiki/Q317309","display_name":"Mental health","level":2,"score":0.6730999946594238},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.6470000147819519},{"id":"https://openalex.org/C189708586","wikidata":"https://www.wikidata.org/wiki/Q1504425","display_name":"Systematic review","level":3,"score":0.555400013923645},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.5418999791145325},{"id":"https://openalex.org/C150966472","wikidata":"https://www.wikidata.org/wiki/Q3410145","display_name":"Psychosocial","level":2,"score":0.5364000201225281},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.5349000096321106},{"id":"https://openalex.org/C2780733359","wikidata":"https://www.wikidata.org/wiki/Q331769","display_name":"Mood","level":2,"score":0.517300009727478},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.4952999949455261},{"id":"https://openalex.org/C2780665704","wikidata":"https://www.wikidata.org/wiki/Q959298","display_name":"Intervention (counseling)","level":2,"score":0.41280001401901245},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.4066999852657318},{"id":"https://openalex.org/C2776035688","wikidata":"https://www.wikidata.org/wiki/Q1606558","display_name":"Affect (linguistics)","level":2,"score":0.3463999927043915},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.3276999890804291},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.2912999987602234},{"id":"https://openalex.org/C2777134132","wikidata":"https://www.wikidata.org/wiki/Q188638","display_name":"Mood disorders","level":3,"score":0.2802000045776367},{"id":"https://openalex.org/C28804328","wikidata":"https://www.wikidata.org/wiki/Q7623693","display_name":"Strictly standardized mean difference","level":3,"score":0.27970001101493835},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.26930001378059387},{"id":"https://openalex.org/C2776478404","wikidata":"https://www.wikidata.org/wiki/Q1105187","display_name":"Cochrane Library","level":3,"score":0.26669999957084656},{"id":"https://openalex.org/C2776674806","wikidata":"https://www.wikidata.org/wiki/Q12135","display_name":"Mental illness","level":3,"score":0.26030001044273376},{"id":"https://openalex.org/C2771230","wikidata":"https://www.wikidata.org/wiki/Q4926699","display_name":"Blinding","level":3,"score":0.25459998846054077},{"id":"https://openalex.org/C19648533","wikidata":"https://www.wikidata.org/wiki/Q691640","display_name":"Evidence-based medicine","level":3,"score":0.2515999972820282}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.70164/jmbr.v3i6.1384","doi":"https://doi.org/10.70164/jmbr.v3i6.1384","is_oa":true,"landing_page_url":"https://doi.org/10.70164/jmbr.v3i6.1384","pdf_url":null,"source":{"id":"https://openalex.org/S4404677169","display_name":"Journal of Medical and Biosciences Research.","issn_l":"2966-1668","issn":["2966-1668"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4404677168","host_organization_name":"Nilton Lins University","host_organization_lineage":["https://openalex.org/P4404677168"],"host_organization_lineage_names":["Nilton Lins University"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medical and Biosciences Research","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.70164/jmbr.v3i6.1384","doi":"https://doi.org/10.70164/jmbr.v3i6.1384","is_oa":true,"landing_page_url":"https://doi.org/10.70164/jmbr.v3i6.1384","pdf_url":null,"source":{"id":"https://openalex.org/S4404677169","display_name":"Journal of Medical and Biosciences Research.","issn_l":"2966-1668","issn":["2966-1668"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4404677168","host_organization_name":"Nilton Lins University","host_organization_lineage":["https://openalex.org/P4404677168"],"host_organization_lineage_names":["Nilton Lins University"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medical and Biosciences Research","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"Background:":[0],"Perinatal":[1],"mood":[2],"and":[3,21,87,99,104,121,151,162,265,285,297,310,316,330,354],"anxiety":[4,284],"disorders":[5,109],"(PMADs)":[6],"affect":[7],"approximately":[8],"10%":[9],"of":[10,38,48,94,147,153,165,304],"pregnant":[11,143,210],"women":[12,40],"globally,":[13],"with":[14,55],"prevalence":[15],"rising":[16],"to":[17,126,232,247,260,274],"15.6%":[18],"in":[19,142,181,191,195,294,361],"low-":[20],"middle-income":[22],"countries":[23,296],"(LMICs).":[24],"The":[25,183],"global":[26],"burden":[27],"has":[28,68],"nearly":[29],"doubled":[30],"over":[31],"the":[32,46,91,200,219,326],"past":[33],"decade,":[34],"yet":[35],"only":[36],"20%":[37],"affected":[39],"receive":[41],"timely,":[42],"appropriate":[43],"treatment.":[44],"Despite":[45],"existence":[47],"19":[49],"systematic":[50,85],"reviews,":[51],"evidence":[52,196,305,363],"remains":[53],"fragmented,":[54],"79%":[56],"rated":[57],"as":[58],"low":[59,62,313,318],"or":[60],"critically":[61],"quality.":[63],"No":[64],"network":[65,88],"meta-analysis":[66,89,213],"(NMA)":[67],"simultaneously":[69],"compared":[70],"all":[71],"major":[72],"intervention":[73,137],"types":[74],"within":[75,175],"a":[76,83,176,357],"single":[77],"analytical":[78],"framework.":[79,202],"Objective:":[80],"To":[81],"conduct":[82],"comprehensive":[84],"review":[86],"comparing":[90],"comparative":[92,328],"efficacy":[93],"psychological,":[95],"physical":[96,309],"(exercise-based),":[97],"psychosocial,":[98,315],"pharmacological":[100,266,320],"interventions":[101,217,240,253,267,299,324,350],"for":[102,138,222,283,298,308,314,319,337,351],"preventing":[103],"treating":[105],"perinatal":[106,139,339,362],"mental":[107,140,340],"health":[108,141,341],"during":[110],"pregnancy.":[111],"Methods:":[112],"We":[113,129,171,204],"searched":[114],"MEDLINE,":[115],"Embase,":[116],"PsycINFO,":[117],"CINAHL,":[118],"Cochrane":[119,168],"CENTRAL,":[120],"trial":[122],"registries":[123],"from":[124],"inception":[125],"May,":[127],"2024.":[128],"included":[130,205],"randomized":[131],"controlled":[132],"trials":[133],"(RCTs)":[134],"evaluating":[135],"any":[136],"women,":[144],"assessing":[145],"outcomes":[146],"depression,":[148],"anxiety,":[149],"stress,":[150],"quality":[152],"life.":[154],"Two":[155],"independent":[156],"reviewers":[157],"screened":[158],"records,":[159],"extracted":[160],"data,":[161],"assessed":[163],"risk":[164],"bias":[166],"using":[167,179,199],"RoB":[169],"2.0.":[170],"performed":[172],"random-effects":[173],"NMA":[174],"frequentist":[177],"framework":[178],"netmeta":[180],"R.":[182],"primary":[184],"outcome":[185],"was":[186,197,306],"standardized":[187],"mean":[188],"difference":[189],"(SMD)":[190],"depressive":[192,224],"symptoms.":[193,342],"Confidence":[194],"evaluated":[198],"CINeMA":[201],"Results:":[203],"87":[206],"RCTs":[207],"involving":[208],"24,312":[209],"women.":[211],"Network":[212],"demonstrated":[214],"that":[215],"physical/exercise-based":[216],"were":[218,281],"most":[220],"effective":[221],"reducing":[223],"symptoms":[225],"(SMD":[226,241,254,268],"=":[227,235,242,250,255,263,269,277],"-0.45,":[228],"95%":[229,244,257,271],"CI:":[230,245,258,272],"-0.62":[231],"-0.28;":[233],"P-score":[234,249,262,276],"0.89),":[236],"followed":[237],"by":[238],"psychological":[239,311],"-0.30,":[243],"-0.44":[246],"-0.16;":[248],"0.72),":[251],"psychosocial":[252],"-0.24,":[256],"-0.40":[259],"-0.08;":[261],"0.58),":[264],"-0.11,":[270],"-0.27":[273],"0.05;":[275],"0.31).":[278],"Similar":[279],"rankings":[280],"observed":[282],"stress":[286],"outcomes.":[287],"Subgroup":[288],"analyses":[289],"revealed":[290],"larger":[291],"effect":[292,329],"sizes":[293],"high-income":[295],"lasting":[300],"\u22658":[301],"weeks.":[302],"Certainty":[303],"moderate":[307],"interventions,":[312],"very":[317],"interventions.":[321],"Conclusions:":[322],"Physical/exercise-based":[323],"demonstrate":[325],"strongest":[327],"should":[331],"be":[332],"considered":[333],"first-line":[334],"scalable":[335],"options":[336],"mild-to-moderate":[338],"These":[343],"findings":[344],"inform":[345],"clinical":[346],"guidelines,":[347],"identify":[348],"optimal":[349],"resource-limited":[352],"settings,":[353],"directly":[355],"address":[356],"WHO-identified":[358],"priority":[359],"gap":[360],"synthesis.":[364]},"counts_by_year":[],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2026-11-12T00:00:00"}