{"id":"https://openalex.org/W7225805808","doi":"https://doi.org/10.1038/s44484-026-00030-6","title":"Ligs-Mamba: a synergistic Mamba network for video breast Cooper\u2019s ligament segmentation","display_name":"Ligs-Mamba: a synergistic Mamba network for video breast Cooper\u2019s ligament segmentation","publication_year":2026,"publication_date":"2026-11-11","ids":{"openalex":"https://openalex.org/W7225805808","doi":"https://doi.org/10.1038/s44484-026-00030-6"},"language":"en","primary_location":{"id":"doi:10.1038/s44484-026-00030-6","doi":"https://doi.org/10.1038/s44484-026-00030-6","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s44484-026-00030-6","pdf_url":"https://www.nature.com/articles/s44484-026-00030-6.pdf","source":{"id":"https://openalex.org/S7407056681","display_name":"npj Digital Surgery","issn_l":"3091-2806","issn":["3091-2806"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Surgery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.nature.com/articles/s44484-026-00030-6.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5161451359","display_name":"Kecheng Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405261251","display_name":"The Hong Kong University of Science and Technology (Guangzhou)","ror":"https://ror.org/050h0vm43","country_code":"CN","type":"education","lineage":["https://openalex.org/I4405261251"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kecheng Wu","raw_affiliation_strings":["Hong Kong University of Science and Technology (Guangzhou), Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hong Kong University of Science and Technology (Guangzhou), Guangzhou, China","institution_ids":["https://openalex.org/I4405261251"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100360519","display_name":"Haiyan Li","orcid":"https://orcid.org/0000-0002-5541-3035","observed_orcids":["https://orcid.org/0000-0002-5541-3035"]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210093460","display_name":"Sixth Affiliated Hospital of Sun Yat-sen University","ror":"https://ror.org/005pe1772","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093460"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haiyan Li","raw_affiliation_strings":["The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China"],"raw_orcid":"https://orcid.org/0000-0002-5541-3035","affiliations":[{"raw_affiliation_string":"The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210093460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046574605","display_name":"Zhaohu Xing","orcid":"https://orcid.org/0009-0002-2502-3578","observed_orcids":["https://orcid.org/0009-0002-2502-3578"]},"institutions":[{"id":"https://openalex.org/I4405261251","display_name":"The Hong Kong University of Science and Technology (Guangzhou)","ror":"https://ror.org/050h0vm43","country_code":"CN","type":"education","lineage":["https://openalex.org/I4405261251"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhaohu Xing","raw_affiliation_strings":["Hong Kong University of Science and Technology (Guangzhou), Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hong Kong University of Science and Technology (Guangzhou), Guangzhou, China","institution_ids":["https://openalex.org/I4405261251"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161435324","display_name":"Yijun Yang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405261251","display_name":"The Hong Kong University of Science and Technology (Guangzhou)","ror":"https://ror.org/050h0vm43","country_code":"CN","type":"education","lineage":["https://openalex.org/I4405261251"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yijun Yang","raw_affiliation_strings":["Hong Kong University of Science and Technology (Guangzhou), Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hong Kong University of Science and Technology (Guangzhou), Guangzhou, China","institution_ids":["https://openalex.org/I4405261251"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161449927","display_name":"Feng Gao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210093460","display_name":"Sixth Affiliated Hospital of Sun Yat-sen University","ror":"https://ror.org/005pe1772","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093460"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Feng Gao","raw_affiliation_strings":["The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210093460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100436460","display_name":"Guang Yang","orcid":"https://orcid.org/0000-0001-7344-7733","observed_orcids":["https://orcid.org/0000-0001-7344-7733"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I4210096640","display_name":"Royal Brompton Hospital","ror":"https://ror.org/00cv4n034","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800036501","https://openalex.org/I4210096640"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Guang Yang","raw_affiliation_strings":["Bioengineering/Imperial-X, Imperial College London, London, UK","Cardiovascular Research Centre, Royal Brompton Hospital, London, UK","National Heart and Lung Institute, Imperial College London, London, UK","School of Biomedical Engineering & Imaging Sciences, King\u2019s College London, London, UK"],"raw_orcid":"https://orcid.org/0000-0001-7344-7733","affiliations":[{"raw_affiliation_string":"Bioengineering/Imperial-X, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"Cardiovascular Research Centre, Royal Brompton Hospital, London, UK","institution_ids":["https://openalex.org/I4210096640"]},{"raw_affiliation_string":"National Heart and Lung Institute, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"School of Biomedical Engineering & Imaging Sciences, King\u2019s College London, London, UK","institution_ids":["https://openalex.org/I183935753"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5161481397","display_name":"Lei Zhu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200769079","display_name":"Hong Kong University of Science and Technology","ror":"https://ror.org/00q4vv597","country_code":"HK","type":"education","lineage":["https://openalex.org/I200769079"]}],"countries":["HK"],"is_corresponding":true,"raw_author_name":"Lei Zhu","raw_affiliation_strings":["Hong Kong University of Science and Technology, Hong Kong SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hong Kong University of Science and Technology, Hong Kong SAR, China","institution_ids":["https://openalex.org/I200769079"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5161481397"],"corresponding_institution_ids":["https://openalex.org/I200769079"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"1","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9779999852180481,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9779999852180481,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.011300000362098217,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10036","display_name":"Advanced Neural Network Applications","score":0.004600000102072954,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[],"concepts":[{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.713100016117096},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.7046999931335449},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.657800018787384},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.6129999756813049},{"id":"https://openalex.org/C2779753412","wikidata":"https://www.wikidata.org/wiki/Q39888","display_name":"Ligament","level":2,"score":0.5776000022888184},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.4683000147342682},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.4375},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.36340001225471497},{"id":"https://openalex.org/C52622490","wikidata":"https://www.wikidata.org/wiki/Q1026626","display_name":"Feature extraction","level":2,"score":0.3431999981403351},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.3409000039100647},{"id":"https://openalex.org/C192209626","wikidata":"https://www.wikidata.org/wiki/Q190909","display_name":"Focus (optics)","level":2,"score":0.3382999897003174},{"id":"https://openalex.org/C2776359362","wikidata":"https://www.wikidata.org/wiki/Q2145286","display_name":"Representation (politics)","level":3,"score":0.32989999651908875},{"id":"https://openalex.org/C184297639","wikidata":"https://www.wikidata.org/wiki/Q177765","display_name":"Biometrics","level":2,"score":0.2971000075340271},{"id":"https://openalex.org/C31601959","wikidata":"https://www.wikidata.org/wiki/Q931309","display_name":"Medical imaging","level":2,"score":0.25839999318122864}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1038/s44484-026-00030-6","doi":"https://doi.org/10.1038/s44484-026-00030-6","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s44484-026-00030-6","pdf_url":"https://www.nature.com/articles/s44484-026-00030-6.pdf","source":{"id":"https://openalex.org/S7407056681","display_name":"npj Digital Surgery","issn_l":"3091-2806","issn":["3091-2806"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Surgery","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1038/s44484-026-00030-6","doi":"https://doi.org/10.1038/s44484-026-00030-6","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s44484-026-00030-6","pdf_url":"https://www.nature.com/articles/s44484-026-00030-6.pdf","source":{"id":"https://openalex.org/S7407056681","display_name":"npj Digital Surgery","issn_l":"3091-2806","issn":["3091-2806"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Surgery","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225805808.pdf","grobid_xml":"https://content.openalex.org/works/W7225805808.grobid-xml"},"referenced_works_count":42,"referenced_works":["https://openalex.org/W1901129140","https://openalex.org/W1994922096","https://openalex.org/W2008359794","https://openalex.org/W2034269173","https://openalex.org/W2194775991","https://openalex.org/W2285968993","https://openalex.org/W2416968644","https://openalex.org/W2752782242","https://openalex.org/W2961348656","https://openalex.org/W2963529609","https://openalex.org/W2963868681","https://openalex.org/W2979907638","https://openalex.org/W2988299447","https://openalex.org/W2996290406","https://openalex.org/W2998449272","https://openalex.org/W3092344722","https://openalex.org/W3138516171","https://openalex.org/W3174565742","https://openalex.org/W3175028288","https://openalex.org/W3202285299","https://openalex.org/W3203497085","https://openalex.org/W4226068227","https://openalex.org/W4226069476","https://openalex.org/W4285040393","https://openalex.org/W4295934810","https://openalex.org/W4387211477","https://openalex.org/W4390784781","https://openalex.org/W4401306839","https://openalex.org/W4402727420","https://openalex.org/W4403063085","https://openalex.org/W4403660530","https://openalex.org/W4403792190","https://openalex.org/W4404810639","https://openalex.org/W4409683197","https://openalex.org/W4410780749","https://openalex.org/W4410915127","https://openalex.org/W4414243662","https://openalex.org/W4415797635","https://openalex.org/W4417031008","https://openalex.org/W7117653398","https://openalex.org/W7118298638","https://openalex.org/W7126374336"],"related_works":[],"abstract_inverted_index":{"Accurate":[0],"segmentation":[1,129],"of":[2,14,113],"breast":[3],"Cooper\u2019s":[4],"(BC)":[5],"ligaments":[6,115],"in":[7,36,52,172],"endoscopic":[8],"mastectomy":[9],"videos":[10,135],"is":[11,143,155],"difficult":[12],"because":[13],"their":[15],"low":[16],"contrast,":[17],"indistinct":[18],"boundaries,":[19],"and":[20,74,123,136,153,174],"interference":[21],"from":[22],"surrounding":[23],"tissues.":[24],"Reliable":[25],"delineation":[26],"supports":[27],"anatomical":[28],"identification":[29],"during":[30],"surgery.":[31],"Mamba":[32,71,78],"has":[33],"shown":[34],"promise":[35],"medical":[37],"image":[38],"analysis.":[39],"Compared":[40],"with":[41],"Transformer":[42],"self-attention,":[43],"its":[44],"selective":[45],"scanning":[46,90,103],"mechanism":[47],"adaptively":[48],"emphasizes":[49],"informative":[50],"features":[51],"long":[53],"sequences.":[54],"We":[55,120],"propose":[56],"Ligs-Mamba,":[57],"a":[58],"Mamba-based":[59],"framework":[60,158],"for":[61,148,160],"video":[62,149],"BC":[63,127,150],"ligament":[64,84,128,151,180],"segmentation.":[65],"It":[66],"comprises":[67],"an":[68,75],"anatomy-aware":[69],"global":[70,88],"(AGM)":[72],"module":[73],"uncertainty-focused":[76],"local":[77,102],"(ULM)":[79],"module.":[80],"AGM":[81],"uses":[82,97],"coarse":[83],"predictions":[85],"to":[86,100],"direct":[87],"feature":[89],"toward":[91],"anatomically":[92],"relevant":[93],"regions,":[94],"whereas":[95],"ULM":[96],"uncertainty":[98],"priors":[99],"focus":[101],"on":[104,164],"ambiguous":[105],"boundaries.":[106],"Together,":[107],"these":[108],"modules":[109],"strengthen":[110],"the":[111,125,144,156],"representation":[112],"low-contrast":[114],"while":[116],"reducing":[117],"background":[118],"interference.":[119],"also":[121],"collect":[122],"annotate":[124],"video-based":[126],"(VLS)":[130],"dataset,":[131],"which":[132],"contains":[133],"90":[134],"6403":[137],"frames.":[138],"To":[139],"our":[140],"knowledge,":[141],"VLS":[142,165],"first":[145,157],"annotated":[146],"dataset":[147],"segmentation,":[152],"Ligs-Mamba":[154,168],"designed":[159],"this":[161],"task.":[162],"Experiments":[163],"show":[166],"that":[167],"outperforms":[169],"state-of-the-art":[170],"methods":[171],"quantitative":[173],"qualitative":[175],"evaluations,":[176],"producing":[177],"more":[178],"accurate":[179],"masks":[181],"under":[182],"challenging":[183],"conditions.":[184]},"counts_by_year":[],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2026-11-12T00:00:00"}