{"id":"https://openalex.org/W7225802908","doi":"https://doi.org/10.21203/rs.3.rs-11410140/v1","title":"Baseline neuroticism and subsequent reporting of doctor- treated glaucoma in the Health and Retirement Study","display_name":"Baseline neuroticism and subsequent reporting of doctor- treated glaucoma in the Health and Retirement Study","publication_year":2026,"publication_date":"2026-11-11","ids":{"openalex":"https://openalex.org/W7225802908","doi":"https://doi.org/10.21203/rs.3.rs-11410140/v1"},"language":"en","primary_location":{"id":"doi:10.21203/rs.3.rs-11410140/v1","doi":"https://doi.org/10.21203/rs.3.rs-11410140/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-11410140/v1","pdf_url":null,"source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.21203/rs.3.rs-11410140/v1","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046258483","display_name":"Chengxiu Liu","orcid":"https://orcid.org/0000-0003-3006-4956","observed_orcids":["https://orcid.org/0000-0003-3006-4956"]},"institutions":[{"id":"https://openalex.org/I4210116869","display_name":"Affiliated Hospital of Qingdao University","ror":"https://ror.org/026e9yy16","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210116869"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chengxiu Liu","raw_affiliation_strings":["Affiliated Hospital of Qingdao University Medical College"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliated Hospital of Qingdao University Medical College","institution_ids":["https://openalex.org/I4210116869"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161455169","display_name":"Jing Lin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210116869","display_name":"Affiliated Hospital of Qingdao University","ror":"https://ror.org/026e9yy16","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210116869"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing Lin","raw_affiliation_strings":["Affiliated Hospital of Qingdao University Medical College"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliated Hospital of Qingdao University Medical College","institution_ids":["https://openalex.org/I4210116869"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101630682","display_name":"Tao Liang","orcid":"https://orcid.org/0000-0003-0568-5072","observed_orcids":["https://orcid.org/0000-0003-0568-5072"]},"institutions":[{"id":"https://openalex.org/I4210116869","display_name":"Affiliated Hospital of Qingdao University","ror":"https://ror.org/026e9yy16","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210116869"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tao Liang","raw_affiliation_strings":["Affiliated Hospital of Qingdao University Medical College"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliated Hospital of Qingdao University Medical College","institution_ids":["https://openalex.org/I4210116869"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210116869"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11040","display_name":"Personality Traits and Psychology","score":0.003800000064074993,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[],"concepts":[{"id":"https://openalex.org/C94612546","wikidata":"https://www.wikidata.org/wiki/Q1540168","display_name":"Neuroticism","level":3,"score":0.8004000186920166},{"id":"https://openalex.org/C2776640315","wikidata":"https://www.wikidata.org/wiki/Q7315941","display_name":"Respondent","level":2,"score":0.7271999716758728},{"id":"https://openalex.org/C2778527774","wikidata":"https://www.wikidata.org/wiki/Q159701","display_name":"Glaucoma","level":2,"score":0.676800012588501},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6328999996185303},{"id":"https://openalex.org/C150966472","wikidata":"https://www.wikidata.org/wiki/Q3410145","display_name":"Psychosocial","level":2,"score":0.5995000004768372},{"id":"https://openalex.org/C2780176501","wikidata":"https://www.wikidata.org/wiki/Q5690755","display_name":"Health and Retirement Study","level":2,"score":0.5658000111579895},{"id":"https://openalex.org/C187288502","wikidata":"https://www.wikidata.org/wiki/Q641118","display_name":"Personality","level":2,"score":0.5224000215530396},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.48489999771118164},{"id":"https://openalex.org/C77350462","wikidata":"https://www.wikidata.org/wiki/Q1125472","display_name":"Confounding","level":2,"score":0.415800005197525},{"id":"https://openalex.org/C2777895361","wikidata":"https://www.wikidata.org/wiki/Q1758614","display_name":"Longitudinal study","level":2,"score":0.4041999876499176},{"id":"https://openalex.org/C2780553607","wikidata":"https://www.wikidata.org/wiki/Q684868","display_name":"Attrition","level":2,"score":0.3903999924659729},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.3596999943256378},{"id":"https://openalex.org/C2865642","wikidata":"https://www.wikidata.org/wiki/Q378132","display_name":"Big Five personality traits","level":3,"score":0.3395000100135803},{"id":"https://openalex.org/C12725497","wikidata":"https://www.wikidata.org/wiki/Q810247","display_name":"Baseline (sea)","level":2,"score":0.3249000012874603},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.32260000705718994},{"id":"https://openalex.org/C171606756","wikidata":"https://www.wikidata.org/wiki/Q506132","display_name":"Psychometrics","level":2,"score":0.322299987077713},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.3183000087738037},{"id":"https://openalex.org/C2780148112","wikidata":"https://www.wikidata.org/wiki/Q1432581","display_name":"Proxy (statistics)","level":2,"score":0.3077000081539154},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.2978000044822693},{"id":"https://openalex.org/C174010058","wikidata":"https://www.wikidata.org/wiki/Q7170643","display_name":"Personality Assessment Inventory","level":3,"score":0.2937000095844269},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.2842000126838684},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.28209999203681946},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.27399998903274536},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.2612000107765198},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.25760000944137573}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.21203/rs.3.rs-11410140/v1","doi":"https://doi.org/10.21203/rs.3.rs-11410140/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-11410140/v1","pdf_url":null,"source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.21203/rs.3.rs-11410140/v1","doi":"https://doi.org/10.21203/rs.3.rs-11410140/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-11410140/v1","pdf_url":null,"source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W881471371","https://openalex.org/W1971486551","https://openalex.org/W1984486743","https://openalex.org/W1994670953","https://openalex.org/W2007848327","https://openalex.org/W2010788802","https://openalex.org/W2017871126","https://openalex.org/W2041359277","https://openalex.org/W2069885338","https://openalex.org/W2071066672","https://openalex.org/W2084007633","https://openalex.org/W2091305718","https://openalex.org/W2142495742","https://openalex.org/W2154117702","https://openalex.org/W2160272053","https://openalex.org/W2169826479","https://openalex.org/W2264767503","https://openalex.org/W2275737843","https://openalex.org/W2316976792","https://openalex.org/W2346464563","https://openalex.org/W2521776509","https://openalex.org/W2594658413","https://openalex.org/W2701526617","https://openalex.org/W2751108361","https://openalex.org/W3128916296","https://openalex.org/W3138578573","https://openalex.org/W3166395129","https://openalex.org/W4381244854","https://openalex.org/W4398205397","https://openalex.org/W4401340535","https://openalex.org/W4403484696","https://openalex.org/W4412070332","https://openalex.org/W4415617225","https://openalex.org/W4416426078","https://openalex.org/W4416426263","https://openalex.org/W7168220239"],"related_works":[],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"Personality":[2],"has":[3],"usually":[4],"been":[5],"measured":[6,260],"after":[7,256,330],"glaucoma":[8,26,64,77,323],"diagnosis,":[9],"limiting":[10],"temporal":[11],"interpretation.":[12],"We":[13],"examined":[14],"whether":[15],"baseline":[16,144,309,339],"neuroticism":[17,188,293,310],"was":[18,55,82,104,190,251,311],"associated":[19,191,312],"with":[20,151,192,232,313],"subsequent":[21,107,319],"survey":[22],"reporting":[23,320,347],"of":[24,86,197,292,300,318,321],"doctor-treated":[25,322],"among":[27],"older":[28,49],"participants":[29,44],"in":[30,56,98,220,324],"the":[31,83,99,105,173,221,233,245,249,287],"Health":[32],"and":[33,70,149,165,180,231,254,265,274,289,296,338,346],"Retirement":[34],"Study":[35],"(HRS).":[36],"Methods":[37],"This":[38],"exploratory":[39],"longitudinal":[40],"analysis":[41,157],"included":[42,134,158],"HRS":[43,234,327],"aged":[45],"65":[46],"years":[47],"or":[48,58,67,109],"whose":[50],"first":[51,106,162],"psychosocial":[52],"leave-behind":[53],"assessment":[54,78],"2006":[57],"2008,":[59],"who":[60,71],"had":[61,72],"no":[62],"positive":[63,111,163],"report":[65],"at":[66,73,93,126,177,182,286],"before":[68,253],"baseline,":[69],"least":[74,94],"one":[75],"later":[76],"through":[79],"2020.":[80],"Neuroticism":[81],"standardized":[84,283],"mean":[85],"four":[87],"Midlife":[88],"Development":[89],"Inventory":[90],"items,":[91],"requiring":[92],"three":[95],"observed":[96],"items":[97],"primary":[100],"analysis.":[101],"The":[102,156],"endpoint":[103],"respondent-":[108],"proxy-reported":[110],"response":[112],"to":[113],"\u201cHas":[114],"a":[115,141,193,298,314],"doctor":[116],"ever":[117],"treated":[118],"you":[119],"for":[120,258,280,332],"glaucoma?\u201d":[121],"Observation":[122],"intervals":[123],"were":[124,218,269,294],"split":[125],"fixed":[127,142],"2-year":[128],"elapsed-time":[129,143],"boundaries.":[130],"Complementary":[131],"log-log":[132],"models":[133],"log":[135],"segment":[136],"duration":[137],"as":[138,348],"an":[139],"offset,":[140],"hazard,":[145],"age,":[146],"sex,":[147],"race/ethnicity,":[148],"education,":[150],"participant-clustered":[152],"standard":[153],"errors.":[154],"Results":[155,217],"7,217":[159],"participants,":[160],"1,067":[161],"reports,":[164],"61,833":[166],"person-years":[167],"(median":[168],"follow-up,":[169],"8.5":[170],"years).":[171],"Of":[172],"events,":[174],"954":[175],"occurred":[176],"respondent":[178,208],"interviews":[179,209],"113":[181],"proxy":[183],"interviews.":[184],"Each":[185],"1-SD":[186],"higher":[187,316],"score":[189],"hazard":[194],"ratio":[195],"(HR)":[196],"1.091":[198],"(95%":[199,214,271,276,304],"CI,":[200,215,229,242,272,277,305],"1.025\u20131.161;":[201],"P":[202],"=":[203],".006).":[204],"Reconstructing":[205],"follow-up":[206],"from":[207],"only":[210],"yielded":[211],"HR":[212,250],"1.082":[213],"1.013\u20131.156).":[216],"similar":[219],"inverse-probability-of-censoring":[222],"weighted":[223],"attrition":[224],"sensitivity":[225],"(HR,":[226,239],"1.086;":[227],"95%":[228,241],"1.018\u20131.159)":[230],"guide-based":[235],"two-of-four-item":[236],"scoring":[237],"rule":[238],"1.090;":[240],"1.024\u20131.160).":[243],"In":[244],"healthcare-use":[246,262],"complete-case":[247],"sample,":[248],"1.076":[252],"1.041":[255],"adjustment":[257,331],"all":[259],"general":[261,333],"variables.":[263],"Four-":[264],"6-year":[266],"landmark":[267],"estimates":[268],"1.072":[270],"0.995\u20131.154)":[273],"1.064":[275],"0.972\u20131.166).":[278],"Accounting":[279],"competing":[281],"death,":[282],"10-year":[284],"probabilities":[285],"25th":[288],"75th":[290],"percentiles":[291],"11.40%":[295],"12.60%,":[297],"difference":[299],"1.20":[301],"percentage":[302],"points":[303],"0.25\u20132.13).":[306],"Conclusions":[307],"Higher":[308],"modestly":[315],"rate":[317],"this":[325],"selected":[326],"cohort.":[328],"Attenuation":[329],"healthcare":[334],"use,":[335],"depressive":[336],"symptoms,":[337],"eye-health":[340],"measures":[341],"leaves":[342],"disease":[343],"occurrence,":[344],"detection,":[345],"unresolved":[349],"explanations.":[350]},"counts_by_year":[],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2026-11-12T00:00:00"}