{"id":"https://openalex.org/W7225798318","doi":"https://doi.org/10.3390/children13111561","title":"Validation of Friedewald, Martin, Sampson and Modified Sampson Equations for Estimating LDL Cholesterol in a Pediatric Population","display_name":"Validation of Friedewald, Martin, Sampson and Modified Sampson Equations for Estimating LDL Cholesterol in a Pediatric Population","publication_year":2026,"publication_date":"2026-11-11","ids":{"openalex":"https://openalex.org/W7225798318","doi":"https://doi.org/10.3390/children13111561"},"language":"en","primary_location":{"id":"doi:10.3390/children13111561","doi":"https://doi.org/10.3390/children13111561","is_oa":true,"landing_page_url":"https://doi.org/10.3390/children13111561","pdf_url":null,"source":{"id":"https://openalex.org/S2736895435","display_name":"Children","issn_l":"2227-9067","issn":["2227-9067"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Children","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/children13111561","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5161428610","display_name":"Celeste Eunice Tizapantzi-Pastrana","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I59361560","display_name":"Instituto Polit\u00e9cnico Nacional","ror":"https://ror.org/059sp8j34","country_code":"MX","type":"education","lineage":["https://openalex.org/I59361560"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Celeste Eunice Tizapantzi-Pastrana","raw_affiliation_strings":["Laboratorio de Modelaci\u00f3n Bioestad\u00edstica, Secci\u00f3n de Estudios de Posgrado e Investigaci\u00f3n, Escuela Superior de Medicina, Instituto Polit\u00e9cnico Nacional, Plan de San Luis y D\u00edaz Mir\u00f3n s/n, Mexico City 11340, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratorio de Modelaci\u00f3n Bioestad\u00edstica, Secci\u00f3n de Estudios de Posgrado e Investigaci\u00f3n, Escuela Superior de Medicina, Instituto Polit\u00e9cnico Nacional, Plan de San Luis y D\u00edaz Mir\u00f3n s/n, Mexico City 11340, Mexico","institution_ids":["https://openalex.org/I59361560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066000428","display_name":"Roberto Rivera-S\u00e1nchez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210153604","display_name":"Hospital Ju\u00e1rez de M\u00e9xico","ror":"https://ror.org/04cepy814","country_code":"MX","type":"healthcare","lineage":["https://openalex.org/I4210153604"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Roberto Rivera-Sanchez","raw_affiliation_strings":["Divisi\u00f3n de Investigaci\u00f3n, Hospital Juarez de Mexico. Av. Instituto Polit\u00e9cnico Nacional, Ciudad de M\u00e9xico 07760, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Divisi\u00f3n de Investigaci\u00f3n, Hospital Juarez de Mexico. Av. Instituto Polit\u00e9cnico Nacional, Ciudad de M\u00e9xico 07760, Mexico","institution_ids":["https://openalex.org/I4210153604"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5099519695","display_name":"Adriana Flores-Miranda","orcid":"https://orcid.org/0009-0007-8916-2979","observed_orcids":["https://orcid.org/0009-0007-8916-2979"]},"institutions":[{"id":"https://openalex.org/I4210153604","display_name":"Hospital Ju\u00e1rez de M\u00e9xico","ror":"https://ror.org/04cepy814","country_code":"MX","type":"healthcare","lineage":["https://openalex.org/I4210153604"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Adriana Flores-Miranda","raw_affiliation_strings":["Divisi\u00f3n de Investigaci\u00f3n, Hospital Juarez de Mexico. Av. Instituto Polit\u00e9cnico Nacional, Ciudad de M\u00e9xico 07760, Mexico"],"raw_orcid":"https://orcid.org/0009-0007-8916-2979","affiliations":[{"raw_affiliation_string":"Divisi\u00f3n de Investigaci\u00f3n, Hospital Juarez de Mexico. Av. Instituto Polit\u00e9cnico Nacional, Ciudad de M\u00e9xico 07760, Mexico","institution_ids":["https://openalex.org/I4210153604"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161447459","display_name":"Sandy Areli Escobar-Alarcon","orcid":"https://orcid.org/0009-0006-8022-1971","observed_orcids":["https://orcid.org/0009-0006-8022-1971"]},"institutions":[{"id":"https://openalex.org/I4405284955","display_name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico, Facultad de Estudios Superiores Iztacala","ror":"https://ror.org/04h0jke78","country_code":"MX","type":"education","lineage":["https://openalex.org/I4405284955","https://openalex.org/I8961855"]},{"id":"https://openalex.org/I8961855","display_name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico","ror":"https://ror.org/01tmp8f25","country_code":"MX","type":"education","lineage":["https://openalex.org/I8961855"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Sandy Areli Escobar-Alarcon","raw_affiliation_strings":["Facultad de Estudios Superiores Iztacala, Universidad Nacional Aut\u00f3noma de M\u00e9xico (UNAM), Av. de los Barrios No. 1, Los Reyes Iztacala, Tlalnepantla de Baz, Estado de Mexico 03100, Mexico"],"raw_orcid":"https://orcid.org/0009-0006-8022-1971","affiliations":[{"raw_affiliation_string":"Facultad de Estudios Superiores Iztacala, Universidad Nacional Aut\u00f3noma de M\u00e9xico (UNAM), Av. de los Barrios No. 1, Los Reyes Iztacala, Tlalnepantla de Baz, Estado de Mexico 03100, Mexico","institution_ids":["https://openalex.org/I4405284955","https://openalex.org/I8961855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093463994","display_name":"Estibeyesbo Said Plascencia-Nieto","orcid":"https://orcid.org/0009-0002-2949-4924","observed_orcids":["https://orcid.org/0009-0002-2949-4924"]},"institutions":[{"id":"https://openalex.org/I59361560","display_name":"Instituto Polit\u00e9cnico Nacional","ror":"https://ror.org/059sp8j34","country_code":"MX","type":"education","lineage":["https://openalex.org/I59361560"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Estibeyesbo Said Plascencia-Nieto","raw_affiliation_strings":["Laboratorio de Modelaci\u00f3n Bioestad\u00edstica, Secci\u00f3n de Estudios de Posgrado e Investigaci\u00f3n, Escuela Superior de Medicina, Instituto Polit\u00e9cnico Nacional, Plan de San Luis y D\u00edaz Mir\u00f3n s/n, Mexico City 11340, Mexico"],"raw_orcid":"https://orcid.org/0009-0002-2949-4924","affiliations":[{"raw_affiliation_string":"Laboratorio de Modelaci\u00f3n Bioestad\u00edstica, Secci\u00f3n de Estudios de Posgrado e Investigaci\u00f3n, Escuela Superior de Medicina, Instituto Polit\u00e9cnico Nacional, Plan de San Luis y D\u00edaz Mir\u00f3n s/n, Mexico City 11340, Mexico","institution_ids":["https://openalex.org/I59361560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046305479","display_name":"Rodrigo Romero\u2010Nava","orcid":"https://orcid.org/0000-0002-8429-5736","observed_orcids":["https://orcid.org/0000-0002-8429-5736"]},"institutions":[{"id":"https://openalex.org/I59361560","display_name":"Instituto Polit\u00e9cnico Nacional","ror":"https://ror.org/059sp8j34","country_code":"MX","type":"education","lineage":["https://openalex.org/I59361560"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Rodrigo Romero-Nava","raw_affiliation_strings":["Laboratorio de Investigaci\u00f3n en Gen\u00e9tica de Enfermedades Metab\u00f3licas, Escuela Superior de Medicina, Instituto Polit\u00e9cnico Nacional, Plan de San Luis y D\u00edaz Mir\u00f3n, Mexico City 11340, Mexico"],"raw_orcid":"https://orcid.org/0000-0002-8429-5736","affiliations":[{"raw_affiliation_string":"Laboratorio de Investigaci\u00f3n en Gen\u00e9tica de Enfermedades Metab\u00f3licas, Escuela Superior de Medicina, Instituto Polit\u00e9cnico Nacional, Plan de San Luis y D\u00edaz Mir\u00f3n, Mexico City 11340, Mexico","institution_ids":["https://openalex.org/I59361560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063595787","display_name":"Mar\u00eda Esther Ocharan-Hern\u00e1ndez","orcid":"https://orcid.org/0000-0003-0433-8116","observed_orcids":["https://orcid.org/0000-0003-0433-8116"]},"institutions":[{"id":"https://openalex.org/I59361560","display_name":"Instituto Polit\u00e9cnico Nacional","ror":"https://ror.org/059sp8j34","country_code":"MX","type":"education","lineage":["https://openalex.org/I59361560"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Mar\u00eda Esther Ocharan-Hern\u00e1ndez","raw_affiliation_strings":["Laboratorio de Se\u00f1alizaci\u00f3n Intracelular, Secci\u00f3n de Estudios de Posgrado e Investigaci\u00f3n, Escuela Superior de Medicina, Instituto Polit\u00e9cnico Nacional, Plan de San Luis y D\u00edaz Mir\u00f3n, Mexico City 11340, Mexico"],"raw_orcid":"https://orcid.org/0000-0003-0433-8116","affiliations":[{"raw_affiliation_string":"Laboratorio de Se\u00f1alizaci\u00f3n Intracelular, Secci\u00f3n de Estudios de Posgrado e Investigaci\u00f3n, Escuela Superior de Medicina, Instituto Polit\u00e9cnico Nacional, Plan de San Luis y D\u00edaz Mir\u00f3n, Mexico City 11340, Mexico","institution_ids":["https://openalex.org/I59361560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161453772","display_name":"Fermin Acosta-Magallanes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I59361560","display_name":"Instituto Polit\u00e9cnico Nacional","ror":"https://ror.org/059sp8j34","country_code":"MX","type":"education","lineage":["https://openalex.org/I59361560"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Fermin Acosta-Magallanes","raw_affiliation_strings":["Unidad Profesional Interdisciplinaria en Ingenier\u00eda y Tecnolog\u00edas Avanzadas, Instituto Polit\u00e9cnico Nacional, Ciudad de M\u00e9xico 07340, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unidad Profesional Interdisciplinaria en Ingenier\u00eda y Tecnolog\u00edas Avanzadas, Instituto Polit\u00e9cnico Nacional, Ciudad de M\u00e9xico 07340, Mexico","institution_ids":["https://openalex.org/I59361560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049951931","display_name":"Francisco Javier Tepepa-L\u00f3pez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I59361560","display_name":"Instituto Polit\u00e9cnico Nacional","ror":"https://ror.org/059sp8j34","country_code":"MX","type":"education","lineage":["https://openalex.org/I59361560"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Francisco Javier Tepepa-L\u00f3pez","raw_affiliation_strings":["Laboratorio de Modelaci\u00f3n Bioestad\u00edstica, Secci\u00f3n de Estudios de Posgrado e Investigaci\u00f3n, Escuela Superior de Medicina, Instituto Polit\u00e9cnico Nacional, Plan de San Luis y D\u00edaz Mir\u00f3n s/n, Mexico City 11340, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratorio de Modelaci\u00f3n Bioestad\u00edstica, Secci\u00f3n de Estudios de Posgrado e Investigaci\u00f3n, Escuela Superior de Medicina, Instituto Polit\u00e9cnico Nacional, Plan de San Luis y D\u00edaz Mir\u00f3n s/n, Mexico City 11340, Mexico","institution_ids":["https://openalex.org/I59361560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053240496","display_name":"Erika G\u00f3mez-Zamora","orcid":"https://orcid.org/0000-0002-0488-7900","observed_orcids":["https://orcid.org/0000-0002-0488-7900"]},"institutions":[{"id":"https://openalex.org/I4210153604","display_name":"Hospital Ju\u00e1rez de M\u00e9xico","ror":"https://ror.org/04cepy814","country_code":"MX","type":"healthcare","lineage":["https://openalex.org/I4210153604"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Erika G\u00f3mez-Zamora","raw_affiliation_strings":["Servicio de Urgencias Pedi\u00e1tricas, Hospital Juarez de Mexico, Av. Instituto Polit\u00e9cnico Nacional, Ciudad de M\u00e9xico 07760, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Servicio de Urgencias Pedi\u00e1tricas, Hospital Juarez de Mexico, Av. Instituto Polit\u00e9cnico Nacional, Ciudad de M\u00e9xico 07760, Mexico","institution_ids":["https://openalex.org/I4210153604"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063492801","display_name":"Gabriela Ib\u00e1\u00f1ez-Cervantes","orcid":"https://orcid.org/0000-0002-7969-0942","observed_orcids":["https://orcid.org/0000-0002-7969-0942"]},"institutions":[{"id":"https://openalex.org/I59361560","display_name":"Instituto Polit\u00e9cnico Nacional","ror":"https://ror.org/059sp8j34","country_code":"MX","type":"education","lineage":["https://openalex.org/I59361560"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Gabriela Ib\u00e1\u00f1ez-Cervantes","raw_affiliation_strings":["Laboratorio de Microbiolog\u00eda y Biolog\u00eda Molecular, Departamento de Desarrollo de Tecnolog\u00edas, Centro Interdisciplinario de Ciencias Marinas, Instituto Polit\u00e9cnico Nacional, C. Instituto Polit\u00e9cnico Nacional s/n, La Paz 23096, Mexico"],"raw_orcid":"https://orcid.org/0000-0002-7969-0942","affiliations":[{"raw_affiliation_string":"Laboratorio de Microbiolog\u00eda y Biolog\u00eda Molecular, Departamento de Desarrollo de Tecnolog\u00edas, Centro Interdisciplinario de Ciencias Marinas, Instituto Polit\u00e9cnico Nacional, C. Instituto Polit\u00e9cnico Nacional s/n, La Paz 23096, Mexico","institution_ids":["https://openalex.org/I59361560"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046430318","display_name":"Cruz Vargas\u2010De\u2010Le\u00f3n","orcid":"https://orcid.org/0000-0001-9428-3619","observed_orcids":["https://orcid.org/0000-0001-9428-3619"]},"institutions":[{"id":"https://openalex.org/I4210153604","display_name":"Hospital Ju\u00e1rez de M\u00e9xico","ror":"https://ror.org/04cepy814","country_code":"MX","type":"healthcare","lineage":["https://openalex.org/I4210153604"]},{"id":"https://openalex.org/I59361560","display_name":"Instituto Polit\u00e9cnico Nacional","ror":"https://ror.org/059sp8j34","country_code":"MX","type":"education","lineage":["https://openalex.org/I59361560"]}],"countries":["MX"],"is_corresponding":true,"raw_author_name":"Cruz Vargas-De-Le\u00f3n","raw_affiliation_strings":["Divisi\u00f3n de Investigaci\u00f3n, Hospital Juarez de Mexico. Av. Instituto Polit\u00e9cnico Nacional, Ciudad de M\u00e9xico 07760, Mexico","Laboratorio de Modelaci\u00f3n Bioestad\u00edstica, Secci\u00f3n de Estudios de Posgrado e Investigaci\u00f3n, Escuela Superior de Medicina, Instituto Polit\u00e9cnico Nacional, Plan de San Luis y D\u00edaz Mir\u00f3n s/n, Mexico City 11340, Mexico"],"raw_orcid":"https://orcid.org/0000-0001-9428-3619","affiliations":[{"raw_affiliation_string":"Divisi\u00f3n de Investigaci\u00f3n, Hospital Juarez de Mexico. Av. Instituto Polit\u00e9cnico Nacional, Ciudad de M\u00e9xico 07760, Mexico","institution_ids":["https://openalex.org/I4210153604"]},{"raw_affiliation_string":"Laboratorio de Modelaci\u00f3n Bioestad\u00edstica, Secci\u00f3n de Estudios de Posgrado e Investigaci\u00f3n, Escuela Superior de Medicina, Instituto Polit\u00e9cnico Nacional, Plan de San Luis y D\u00edaz Mir\u00f3n s/n, Mexico City 11340, Mexico","institution_ids":["https://openalex.org/I59361560"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5046430318"],"corresponding_institution_ids":["https://openalex.org/I4210153604","https://openalex.org/I59361560"],"apc_list":{"value":2400,"currency":"CHF","value_usd":2896},"apc_paid":{"value":2400,"currency":"CHF","value_usd":2896},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"13","issue":"11","first_page":"1561","last_page":"1561"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.9765999913215637,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.9765999913215637,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.006000000052154064,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11314","display_name":"Clinical Laboratory Practices and Quality Control","score":0.005900000222027302,"subfield":{"id":"https://openalex.org/subfields/3607","display_name":"Medical Laboratory Technology"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[],"concepts":[{"id":"https://openalex.org/C104709138","wikidata":"https://www.wikidata.org/wiki/Q1671540","display_name":"Intraclass correlation","level":3,"score":0.7457000017166138},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7297999858856201},{"id":"https://openalex.org/C2781059462","wikidata":"https://www.wikidata.org/wiki/Q5158906","display_name":"Concordance correlation coefficient","level":2,"score":0.5060999989509583},{"id":"https://openalex.org/C2780092901","wikidata":"https://www.wikidata.org/wiki/Q3433612","display_name":"Correlation coefficient","level":2,"score":0.5019000172615051},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.47600001096725464},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.43950000405311584},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.43709999322891235},{"id":"https://openalex.org/C160798450","wikidata":"https://www.wikidata.org/wiki/Q4230870","display_name":"Concordance","level":2,"score":0.435699999332428},{"id":"https://openalex.org/C58471807","wikidata":"https://www.wikidata.org/wiki/Q327120","display_name":"Receiver operating characteristic","level":2,"score":0.42250001430511475},{"id":"https://openalex.org/C9893847","wikidata":"https://www.wikidata.org/wiki/Q1425625","display_name":"Reproducibility","level":2,"score":0.4032000005245209},{"id":"https://openalex.org/C139945424","wikidata":"https://www.wikidata.org/wiki/Q1940696","display_name":"Mean squared error","level":2,"score":0.3995000123977661},{"id":"https://openalex.org/C2994423189","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Total cholesterol","level":3,"score":0.36079999804496765},{"id":"https://openalex.org/C73782692","wikidata":"https://www.wikidata.org/wiki/Q196372","display_name":"Random error","level":2,"score":0.3425000011920929},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.33980000019073486},{"id":"https://openalex.org/C117220453","wikidata":"https://www.wikidata.org/wiki/Q5172842","display_name":"Correlation","level":2,"score":0.3330000042915344},{"id":"https://openalex.org/C21200559","wikidata":"https://www.wikidata.org/wiki/Q7451068","display_name":"Sensitivity (control systems)","level":2,"score":0.32989999651908875},{"id":"https://openalex.org/C89838059","wikidata":"https://www.wikidata.org/wiki/Q623738","display_name":"Coefficient of variation","level":2,"score":0.3276999890804291},{"id":"https://openalex.org/C2780072125","wikidata":"https://www.wikidata.org/wiki/Q28350","display_name":"Lipoprotein","level":3,"score":0.3084000051021576},{"id":"https://openalex.org/C128990827","wikidata":"https://www.wikidata.org/wiki/Q192830","display_name":"Coefficient of determination","level":2,"score":0.30640000104904175},{"id":"https://openalex.org/C122383733","wikidata":"https://www.wikidata.org/wiki/Q865920","display_name":"Approximation error","level":2,"score":0.30230000615119934},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.2964000105857849},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.2906000018119812},{"id":"https://openalex.org/C105054674","wikidata":"https://www.wikidata.org/wiki/Q3707381","display_name":"Mean difference","level":3,"score":0.28870001435279846},{"id":"https://openalex.org/C55078378","wikidata":"https://www.wikidata.org/wiki/Q1136628","display_name":"Pearson product-moment correlation coefficient","level":2,"score":0.27799999713897705},{"id":"https://openalex.org/C76318530","wikidata":"https://www.wikidata.org/wiki/Q16833590","display_name":"Area under the curve","level":2,"score":0.26179999113082886},{"id":"https://openalex.org/C2993922820","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Serum cholesterol","level":3,"score":0.2587999999523163},{"id":"https://openalex.org/C100253034","wikidata":"https://www.wikidata.org/wiki/Q196372","display_name":"Systematic error","level":2,"score":0.25369998812675476},{"id":"https://openalex.org/C3019550498","wikidata":"https://www.wikidata.org/wiki/Q28749","display_name":"Ldl cholesterol","level":3,"score":0.2529999911785126}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.3390/children13111561","doi":"https://doi.org/10.3390/children13111561","is_oa":true,"landing_page_url":"https://doi.org/10.3390/children13111561","pdf_url":null,"source":{"id":"https://openalex.org/S2736895435","display_name":"Children","issn_l":"2227-9067","issn":["2227-9067"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Children","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.3390/children13111561","doi":"https://doi.org/10.3390/children13111561","is_oa":true,"landing_page_url":"https://doi.org/10.3390/children13111561","pdf_url":null,"source":{"id":"https://openalex.org/S2736895435","display_name":"Children","issn_l":"2227-9067","issn":["2227-9067"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Children","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W1807577609","https://openalex.org/W1970530088","https://openalex.org/W2015795623","https://openalex.org/W2024718809","https://openalex.org/W2039240409","https://openalex.org/W2052341239","https://openalex.org/W2054299101","https://openalex.org/W2069378996","https://openalex.org/W2116404316","https://openalex.org/W2136148671","https://openalex.org/W2152575748","https://openalex.org/W2159759971","https://openalex.org/W2176998994","https://openalex.org/W2262354148","https://openalex.org/W2313339984","https://openalex.org/W2315613231","https://openalex.org/W2327037637","https://openalex.org/W2509346813","https://openalex.org/W2550258335","https://openalex.org/W2556912902","https://openalex.org/W2621170278","https://openalex.org/W2809624198","https://openalex.org/W2999309192","https://openalex.org/W3007660274","https://openalex.org/W3033851646","https://openalex.org/W3126232929","https://openalex.org/W3134644708","https://openalex.org/W3138166322","https://openalex.org/W3217136063","https://openalex.org/W4205123622","https://openalex.org/W4205134630","https://openalex.org/W4206613703","https://openalex.org/W4242289937","https://openalex.org/W4306683538","https://openalex.org/W4313559091","https://openalex.org/W4378782259","https://openalex.org/W4389002814","https://openalex.org/W4399609344","https://openalex.org/W4402898423","https://openalex.org/W4412132082","https://openalex.org/W4413246431","https://openalex.org/W4416571447"],"related_works":[],"abstract_inverted_index":{"Background:":[0],"Accurate":[1],"estimation":[2,23,135,182,274],"of":[3,21,38,94,119,271],"low-density":[4,53],"lipoprotein":[5,54,56,61],"cholesterol":[6,57,62],"(LDL-C)":[7],"is":[8],"essential":[9],"for":[10,48,133,164,283],"cardiovascular":[11,288],"risk":[12,289],"assessment":[13,286],"in":[14,280],"pediatric":[15,75,281],"populations,":[16],"yet":[17],"the":[18,31,39,84,128,161,180,194,199,212,216,225,236,242,247,258,262,269,277],"comparative":[19],"performance":[20,37,132],"available":[22],"equations":[24,47,189,207,275],"remains":[25],"insufficiently":[26],"characterized.":[27],"This":[28],"study":[29,70],"evaluated":[30],"agreement,":[32],"systematic":[33,204],"bias,":[34,107],"and":[35,44,51,59,112,153,171,186,202,222,254,287],"diagnostic":[36,113,210],"Friedewald,":[40],"Martin,":[41],"original":[42,187],"Sampson,":[43],"Modified":[45,124,233,243],"Sampson":[46,125,188,234,244],"estimating":[49],"LDL-C":[50,117,134,253,273],"derived":[52,255],"cholesterol-to-high-density":[55],"(LDL/HDL-C)":[58],"triglyceride-to-low-density":[60],"(TG/LDL-C)":[63],"ratios.":[64],"Methods:":[65],"A":[66],"prospective":[67],"cross-sectional":[68],"agreement":[69,163,201,250],"was":[71,81],"conducted":[72],"among":[73],"500":[74],"patients.":[76],"Agreement":[77],"with":[78,179,251],"laboratory":[79,252],"measurements":[80],"assessed":[82],"using":[83],"intraclass":[85],"correlation":[86,90],"coefficient":[87,91,93],"(ICC),":[88],"concordance":[89],"(CCC),":[92],"determination":[95],"(R2),":[96],"root":[97],"mean":[98,102],"square":[99],"error":[100,104],"(RMSE),":[101],"absolute":[103],"(MAE),":[105],"percentage":[106],"Bland\u2013Altman":[108],"analysis,":[109],"Passing\u2013Bablok":[110],"regression,":[111],"accuracy":[114,218],"at":[115],"an":[116],"cut-off":[118],"110":[120],"mg/dL.":[121],"Results:":[122],"The":[123,184],"equation":[126,196,214,245,260,279],"demonstrated":[127,198],"best":[129],"overall":[130],"analytical":[131,249],"(ICC":[136,166,174],"=":[137,140,143,147,151,167,169,175,177],"0.931;":[138],"CCC":[139,168,176],"0.930;":[141],"RMSE":[142],"8.62":[144],"mg/dL;":[145,149],"MAE":[146],"6.73":[148],"bias":[150],"\u22120.805%)":[152],"showed":[154,190,208,235,261],"no":[155],"proportional":[156],"bias.":[157,205],"It":[158],"also":[159],"provided":[160,246],"highest":[162,217,237],"LDL/HDL-C":[165],"0.962)":[170],"TG/LDL-C":[172],"ratios":[173],"0.965),":[178],"lowest":[181,200],"errors.":[183],"Martin":[185,213,259],"intermediate":[191],"performance,":[192],"whereas":[193,257],"Friedewald":[195,278],"consistently":[197],"greatest":[203],"All":[206],"excellent":[209],"accuracy;":[211],"achieved":[215],"(94.40%),":[219],"specificity":[220],"(97.86%),":[221],"area":[223],"under":[224],"receiver":[226],"operating":[227],"characteristic":[228],"curve":[229],"(AUC)":[230],"(0.980),":[231],"while":[232],"sensitivity":[238],"(78.75%).":[239],"Conclusions:":[240],"Overall,":[241],"closest":[248],"ratios,":[256],"strongest":[263],"classification":[264],"performance.":[265],"These":[266],"findings":[267],"support":[268],"use":[270],"newer":[272],"over":[276],"populations":[282],"improved":[284],"lipid":[285],"stratification.":[290]},"counts_by_year":[],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2026-11-12T00:00:00"}