{"id":"https://openalex.org/W7225798134","doi":"https://doi.org/10.1038/s41598-026-79042-8","title":"Association between GLP-1 receptor agonist use and risk of repeat colonoscopy: a real-world cohort study with exploratory discontinuation analyses","display_name":"Association between GLP-1 receptor agonist use and risk of repeat colonoscopy: a real-world cohort study with exploratory discontinuation analyses","publication_year":2026,"publication_date":"2026-11-11","ids":{"openalex":"https://openalex.org/W7225798134","doi":"https://doi.org/10.1038/s41598-026-79042-8"},"language":"en","primary_location":{"id":"doi:10.1038/s41598-026-79042-8","doi":"https://doi.org/10.1038/s41598-026-79042-8","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-026-79042-8","pdf_url":null,"source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1038/s41598-026-79042-8","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089641395","display_name":"Kuang\u2010Yi Sung","orcid":"https://orcid.org/0000-0003-1100-6152","observed_orcids":["https://orcid.org/0000-0003-1100-6152"]},"institutions":[{"id":"https://openalex.org/I114150738","display_name":"Fu Jen Catholic University","ror":"https://ror.org/04je98850","country_code":"TW","type":"education","lineage":["https://openalex.org/I114150738"]},{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Kuan-Yi Sung","raw_affiliation_strings":["Division of Gastroenterology and Hepatology, Department of Internal Medicine, Fu Jen Catholic University Hospital, New Taipei, Taiwan, ROC","Institute of Biomedical Informatics and Health Innovation Center, National Yang Ming Chiao Tung University, No. 155, Section 2, Linong Street, Taipei, 11221, Taiwan, ROC","School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei, Taiwan, ROC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, Department of Internal Medicine, Fu Jen Catholic University Hospital, New Taipei, Taiwan, ROC","institution_ids":["https://openalex.org/I114150738"]},{"raw_affiliation_string":"Institute of Biomedical Informatics and Health Innovation Center, National Yang Ming Chiao Tung University, No. 155, Section 2, Linong Street, Taipei, 11221, Taiwan, ROC","institution_ids":["https://openalex.org/I148366613"]},{"raw_affiliation_string":"School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei, Taiwan, ROC","institution_ids":["https://openalex.org/I114150738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161491958","display_name":"Ping-Hsin Hsieh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210132871","display_name":"University of Maryland Medical Center Midtown Campus","ror":"https://ror.org/03k0fhh26","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I14285509","https://openalex.org/I4210132871"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ping-Hsin Hsieh","raw_affiliation_strings":["Department of Medicine, University of Maryland Medical Center Midtown Campus, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of Maryland Medical Center Midtown Campus, Maryland, USA","institution_ids":["https://openalex.org/I4210132871"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5128201882","display_name":"Yen-Po Wang","orcid":"https://orcid.org/0000-0002-3769-0020","observed_orcids":["https://orcid.org/0000-0002-3769-0020"]},"institutions":[{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]},{"id":"https://openalex.org/I2803004286","display_name":"Taipei Veterans General Hospital","ror":"https://ror.org/03ymy8z76","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I2803004286"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Yen-Po Wang","raw_affiliation_strings":["Department of Medicine, Endoscopy Center for Diagnosis and Treatment, Taipei Veterans General Hospital, Taipei, Taiwan, ROC","Department of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC","Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC","Institute of Brain Science, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Endoscopy Center for Diagnosis and Treatment, Taipei Veterans General Hospital, Taipei, Taiwan, ROC","institution_ids":["https://openalex.org/I2803004286"]},{"raw_affiliation_string":"Department of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC","institution_ids":["https://openalex.org/I148366613"]},{"raw_affiliation_string":"Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC","institution_ids":["https://openalex.org/I2803004286"]},{"raw_affiliation_string":"Institute of Brain Science, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC","institution_ids":["https://openalex.org/I148366613"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060709723","display_name":"Fang-Yu Chen","orcid":"https://orcid.org/0000-0001-6246-6867","observed_orcids":["https://orcid.org/0000-0001-6246-6867"]},"institutions":[{"id":"https://openalex.org/I114150738","display_name":"Fu Jen Catholic University","ror":"https://ror.org/04je98850","country_code":"TW","type":"education","lineage":["https://openalex.org/I114150738"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Fang-Yu Chen","raw_affiliation_strings":["Division of Endocrinology and Metabolism, Department of Internal Medicine, Fu Jen Catholic University Hospital, New Taipei, Taiwan, ROC","Graduate Institute of Applied Science and Engineering, Fu Jen Catholic University, New Taipei City, Taiwan, ROC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Endocrinology and Metabolism, Department of Internal Medicine, Fu Jen Catholic University Hospital, New Taipei, Taiwan, ROC","institution_ids":["https://openalex.org/I114150738"]},{"raw_affiliation_string":"Graduate Institute of Applied Science and Engineering, Fu Jen Catholic University, New Taipei City, Taiwan, ROC","institution_ids":["https://openalex.org/I114150738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113035007","display_name":"Pin-Hsien Lai","orcid":"https://orcid.org/0009-0004-2373-5509","observed_orcids":["https://orcid.org/0009-0004-2373-5509"]},"institutions":[{"id":"https://openalex.org/I4210104362","display_name":"Chung Shan Medical University Hospital","ror":"https://ror.org/01abtsn51","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210104362"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Pin-Hsien Lai","raw_affiliation_strings":["Department of Medical Imaging, Chung Shan Medical University Hospital, Taichung, Taiwan, ROC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Imaging, Chung Shan Medical University Hospital, Taichung, Taiwan, ROC","institution_ids":["https://openalex.org/I4210104362"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133674084","display_name":"Chi-Yang Chang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114150738","display_name":"Fu Jen Catholic University","ror":"https://ror.org/04je98850","country_code":"TW","type":"education","lineage":["https://openalex.org/I114150738"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chi-Yang Chang","raw_affiliation_strings":["Division of Gastroenterology and Hepatology, Department of Internal Medicine, Fu Jen Catholic University Hospital, New Taipei, Taiwan, ROC","School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei, Taiwan, ROC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, Department of Internal Medicine, Fu Jen Catholic University Hospital, New Taipei, Taiwan, ROC","institution_ids":["https://openalex.org/I114150738"]},{"raw_affiliation_string":"School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei, Taiwan, ROC","institution_ids":["https://openalex.org/I114150738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024721601","display_name":"Yee Hui Yeo","orcid":"https://orcid.org/0000-0002-2703-5954","observed_orcids":["https://orcid.org/0000-0002-2703-5954"]},"institutions":[{"id":"https://openalex.org/I1282927834","display_name":"Cedars-Sinai Medical Center","ror":"https://ror.org/02pammg90","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yee Hui Yeo","raw_affiliation_strings":["Karsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Karsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1282927834"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5157852229","display_name":"Chun-Ying Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]},{"id":"https://openalex.org/I165441096","display_name":"National Health Research Institutes","ror":"https://ror.org/02r6fpx29","country_code":"TW","type":"nonprofit","lineage":["https://openalex.org/I165441096"]},{"id":"https://openalex.org/I184693016","display_name":"China Medical University","ror":"https://ror.org/00v408z34","country_code":"TW","type":"education","lineage":["https://openalex.org/I184693016"]},{"id":"https://openalex.org/I2803004286","display_name":"Taipei Veterans General Hospital","ror":"https://ror.org/03ymy8z76","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I2803004286"]},{"id":"https://openalex.org/I4210091773","display_name":"Taichung Veterans General Hospital","ror":"https://ror.org/00e87hq62","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210091773"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Chun-Ying Wu","raw_affiliation_strings":["Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan, ROC","Department of Public Health, China Medical University, Taichung, Taiwan, ROC","Division of Translational Research, Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC","Institute of Biomedical Informatics and Health Innovation Center, National Yang Ming Chiao Tung University, No. 155, Section 2, Linong Street, Taipei, 11221, Taiwan, ROC","National Institute of Cancer Research and Institute of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan, ROC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan, ROC","institution_ids":["https://openalex.org/I4210091773"]},{"raw_affiliation_string":"Department of Public Health, China Medical University, Taichung, Taiwan, ROC","institution_ids":["https://openalex.org/I184693016"]},{"raw_affiliation_string":"Division of Translational Research, Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC","institution_ids":["https://openalex.org/I2803004286"]},{"raw_affiliation_string":"Institute of Biomedical Informatics and Health Innovation Center, National Yang Ming Chiao Tung University, No. 155, Section 2, Linong Street, Taipei, 11221, Taiwan, ROC","institution_ids":["https://openalex.org/I148366613"]},{"raw_affiliation_string":"National Institute of Cancer Research and Institute of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan, ROC","institution_ids":["https://openalex.org/I165441096"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5157852229"],"corresponding_institution_ids":["https://openalex.org/I148366613","https://openalex.org/I165441096","https://openalex.org/I184693016","https://openalex.org/I2803004286","https://openalex.org/I4210091773"],"apc_list":{"value":2690,"currency":"USD","value_usd":2690},"apc_paid":{"value":2690,"currency":"USD","value_usd":2690},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.8062000274658203,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.8062000274658203,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10552","display_name":"Colorectal Cancer Screening and Detection","score":0.10170000046491623,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.0215000007301569,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[],"concepts":[{"id":"https://openalex.org/C2778715236","wikidata":"https://www.wikidata.org/wiki/Q55622662","display_name":"Discontinuation","level":2,"score":0.9280999898910522},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.840399980545044},{"id":"https://openalex.org/C2778435480","wikidata":"https://www.wikidata.org/wiki/Q840387","display_name":"Colonoscopy","level":4,"score":0.7383999824523926},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.614300012588501},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.5684000253677368},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.5620999932289124},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.43309998512268066},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.42800000309944153},{"id":"https://openalex.org/C38180746","wikidata":"https://www.wikidata.org/wiki/Q1952580","display_name":"Multivariate analysis","level":2,"score":0.3619000017642975},{"id":"https://openalex.org/C185280430","wikidata":"https://www.wikidata.org/wiki/Q14909910","display_name":"Glucagon-like peptide 1 receptor","level":4,"score":0.30250000953674316},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.29600000381469727},{"id":"https://openalex.org/C2778938600","wikidata":"https://www.wikidata.org/wiki/Q389934","display_name":"Agonist","level":3,"score":0.29269999265670776},{"id":"https://openalex.org/C23131810","wikidata":"https://www.wikidata.org/wiki/Q818574","display_name":"Observational study","level":2,"score":0.28439998626708984},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.2799000144004822},{"id":"https://openalex.org/C205545832","wikidata":"https://www.wikidata.org/wiki/Q17156455","display_name":"Young adult","level":2,"score":0.27559998631477356},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.2712000012397766},{"id":"https://openalex.org/C2779668873","wikidata":"https://www.wikidata.org/wiki/Q6693756","display_name":"Lower risk","level":3,"score":0.2712000012397766},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.26010000705718994},{"id":"https://openalex.org/C146304588","wikidata":"https://www.wikidata.org/wiki/Q961652","display_name":"Case-control study","level":2,"score":0.2531999945640564},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.25099998712539673}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1038/s41598-026-79042-8","doi":"https://doi.org/10.1038/s41598-026-79042-8","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-026-79042-8","pdf_url":null,"source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1038/s41598-026-79042-8","doi":"https://doi.org/10.1038/s41598-026-79042-8","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-026-79042-8","pdf_url":null,"source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"Abstract":[0],"While":[1],"glucagon-like":[2],"peptide-1":[3],"receptor":[4],"agonists":[5],"(GLP-1":[6],"RAs)":[7],"are":[8,295],"increasingly":[9],"used":[10],"for":[11],"diabetes":[12],"and":[13,34,37,73,110,118,178,200,219,262,268],"obesity,":[14],"their":[15],"effects":[16],"on":[17,86],"gastrointestinal":[18],"motility":[19],"have":[20],"raised":[21],"concern":[22],"about":[23],"colonoscopy":[24,36,94,151,241,256],"outcomes.":[25],"We":[26,45],"evaluated":[27],"the":[28,52,189,263,279],"association":[29,190],"between":[30,70],"GLP-1":[31,77,132,140,230],"RA":[32,78,133,141,231],"use":[33,142,232],"repeat":[35,93,150,240,255],"performed":[38],"exploratory":[39,100],"analyses":[40,101,112,265],"of":[41,102,149,239],"pre-procedural":[42,285],"discontinuation":[43,103,209,228,264,286],"intervals.":[44],"conducted":[46],"a":[47,146,226,236,246,258,283],"retrospective":[48],"cohort":[49],"study":[50],"using":[51],"TriNetX":[53],"Global":[54],"Collaborative":[55],"Network.":[56],"The":[57,89],"analysis":[58],"was":[59,92,143,233],"restricted":[60],"to":[61,107],"adults":[62],"aged":[63],"18\u201390":[64],"years":[65],"with":[66,84,137,145,160,212,235,290],"an":[67],"index":[68],"procedure":[69],"January":[71,74],"2021":[72],"2025.":[75],"Long-term":[76],"users":[79,124,134],"were":[80,125,135,266],"propensity-score":[81,129],"matched":[82],"1:1":[83],"non-users":[85],"44":[87],"covariates.":[88],"primary":[90],"outcome":[91,261],"within":[95,152,242],"12":[96,153],"months.":[97],"Stratified":[98],"analyses,":[99],"intervals":[104,218],"from":[105],"0":[106],"8":[108],"weeks,":[109],"active-comparator":[111,187,252],"against":[113],"dipeptidyl":[114],"peptidase-4":[115],"(DPP-4)":[116],"inhibitor":[117,123],"sodium-glucose":[119],"co-transporter":[120],"2":[121,179],"(SGLT2)":[122],"also":[126],"performed.":[127],"After":[128],"matching,":[130],"20,490":[131,138],"compared":[136],"non-users.":[139],"associated":[144,234],"higher":[147,237],"risk":[148],"months":[154,165,172,180],"(RR":[155,166,173,181,195,203],"1.50,":[156],"95%":[157,168,175,183,197,205],"CI":[158,169,176,184,198,206],"1.39\u20131.61),":[159],"similar":[161],"associations":[162],"at":[163],"6":[164],"1.61,":[167],"1.48\u20131.75),":[170],"3":[171],"1.75,":[174],"1.59\u20131.94),":[177],"1.86,":[182],"1.66\u20132.08).":[185],"In":[186],"analysis,":[188],"persisted":[191],"versus":[192],"DPP-4":[193],"inhibitors":[194,202],"1.41,":[196],"1.21\u20131.63)":[199],"SGLT2":[201],"1.26,":[204],"1.15\u20131.38).":[207],"Exploratory":[208],"estimates":[210],"attenuated":[211],"longer":[213],"intervals,":[214],"but":[215],"overlapping":[216],"confidence":[217],"decreasing":[220],"stratum":[221],"sizes":[222],"did":[223],"not":[224,273],"identify":[225],"definitive":[227],"threshold.":[229],"likelihood":[238],"one":[243],"year":[244],"in":[245,251],"contemporary,":[247],"propensity-score-matched":[248],"cohort,":[249],"including":[250],"analyses.":[253],"Because":[254],"is":[257],"non-specific":[259],"healthcare-utilization":[260],"observational":[267],"exploratory,":[269],"these":[270],"findings":[271],"do":[272],"establish":[274],"inadequate":[275],"bowel":[276],"preparation":[277],"as":[278],"mechanism":[280],"or":[281],"support":[282],"specific":[284],"interval.":[287],"Prospective":[288],"studies":[289],"directly":[291],"measured":[292],"bowel-preparation":[293],"quality":[294],"needed.":[296]},"counts_by_year":[],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2026-11-12T00:00:00"}