{"id":"https://openalex.org/W7225798092","doi":"https://doi.org/10.1021/acs.jafc.6c11339","title":"Substrate Versatility and Regiocontrol of Licorice Flavonoid Prenyltransferase GgFPT3 for the Biosynthesis of Diverse Prenylated Flavonoid Natural Products","display_name":"Substrate Versatility and Regiocontrol of Licorice Flavonoid Prenyltransferase GgFPT3 for the Biosynthesis of Diverse Prenylated Flavonoid Natural Products","publication_year":2026,"publication_date":"2026-11-11","ids":{"openalex":"https://openalex.org/W7225798092","doi":"https://doi.org/10.1021/acs.jafc.6c11339"},"language":"en","primary_location":{"id":"doi:10.1021/acs.jafc.6c11339","doi":"https://doi.org/10.1021/acs.jafc.6c11339","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acs.jafc.6c11339","pdf_url":null,"source":{"id":"https://openalex.org/S134644764","display_name":"Journal of Agricultural and Food Chemistry","issn_l":"0021-8561","issn":["0021-8561","1520-5118"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Agricultural and Food Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5158822797","display_name":"Xiaoling Ma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210120696","display_name":"South China Botanical Garden","ror":"https://ror.org/01xqdxh54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210120696"]},{"id":"https://openalex.org/I4405278620","display_name":"Quanzhou Medical College","ror":"https://ror.org/009xp3h24","country_code":"CN","type":"education","lineage":["https://openalex.org/I4405278620"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoling Ma","raw_affiliation_strings":["Quanzhou Medical College , , , ,","South China Botanical Garden, Chinese Academy of Sciences , , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Quanzhou Medical College , , , ,","institution_ids":["https://openalex.org/I4405278620"]},{"raw_affiliation_string":"South China Botanical Garden, Chinese Academy of Sciences , , ,","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210120696"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101730165","display_name":"Xiaoman Yang","orcid":"https://orcid.org/0000-0001-6144-1131","observed_orcids":["https://orcid.org/0000-0001-6144-1131"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210120696","display_name":"South China Botanical Garden","ror":"https://ror.org/01xqdxh54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210120696"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoman Yang","raw_affiliation_strings":["South China Botanical Garden, Chinese Academy of Sciences , , ,","University of Chinese Academy of Sciences , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"South China Botanical Garden, Chinese Academy of Sciences , , ,","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210120696"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences , ,","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110576233","display_name":"Ningxin Jiang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210120696","display_name":"South China Botanical Garden","ror":"https://ror.org/01xqdxh54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210120696"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ningxin Jiang","raw_affiliation_strings":["South China Botanical Garden, Chinese Academy of Sciences , , ,","University of Chinese Academy of Sciences , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"South China Botanical Garden, Chinese Academy of Sciences , , ,","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210120696"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences , ,","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042407241","display_name":"Xinghao Zhang","orcid":"https://orcid.org/0000-0002-5472-3891","observed_orcids":["https://orcid.org/0000-0002-5472-3891","https://orcid.org/0000-0002-3466-4628"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210120696","display_name":"South China Botanical Garden","ror":"https://ror.org/01xqdxh54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210120696"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinghao Zhang","raw_affiliation_strings":["South China Botanical Garden, Chinese Academy of Sciences , , ,","University of Chinese Academy of Sciences , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"South China Botanical Garden, Chinese Academy of Sciences , , ,","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210120696"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences , ,","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161317406","display_name":"Xiaoyi Wei","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210120696","display_name":"South China Botanical Garden","ror":"https://ror.org/01xqdxh54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210120696"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoyi Wei","raw_affiliation_strings":["South China Botanical Garden, Chinese Academy of Sciences , , ,","University of Chinese Academy of Sciences , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"South China Botanical Garden, Chinese Academy of Sciences , , ,","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210120696"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences , ,","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5143850787","display_name":"Yuping Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210120696","display_name":"South China Botanical Garden","ror":"https://ror.org/01xqdxh54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210120696"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuping Li","raw_affiliation_strings":["South China Botanical Garden, Chinese Academy of Sciences , , ,","University of Chinese Academy of Sciences , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"South China Botanical Garden, Chinese Academy of Sciences , , ,","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210120696"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences , ,","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161474298","display_name":"Shancen Zhao","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shancen Zhao","raw_affiliation_strings":["Beijing Life Science Academy , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Life Science Academy , ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056209403","display_name":"Wang Ying","orcid":"https://orcid.org/0000-0001-8056-3791","observed_orcids":["https://orcid.org/0000-0001-8056-3791"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210120696","display_name":"South China Botanical Garden","ror":"https://ror.org/01xqdxh54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210120696"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ying Wang","raw_affiliation_strings":["South China Botanical Garden, Chinese Academy of Sciences , , ,","University of Chinese Academy of Sciences , ,"],"raw_orcid":"https://orcid.org/0000-0001-8056-3791","affiliations":[{"raw_affiliation_string":"South China Botanical Garden, Chinese Academy of Sciences , , ,","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210120696"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences , ,","institution_ids":["https://openalex.org/I4210165038"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100711505","display_name":"Yongqing Li","orcid":"https://orcid.org/0000-0001-8017-2045","observed_orcids":["https://orcid.org/0000-0001-8017-2045"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210120696","display_name":"South China Botanical Garden","ror":"https://ror.org/01xqdxh54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210120696"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yongqing Li","raw_affiliation_strings":["South China Botanical Garden, Chinese Academy of Sciences , , ,","University of Chinese Academy of Sciences , ,"],"raw_orcid":"https://orcid.org/0000-0001-8017-2045","affiliations":[{"raw_affiliation_string":"South China Botanical Garden, Chinese Academy of Sciences , , ,","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210120696"]},{"raw_affiliation_string":"University of Chinese Academy of Sciences , ,","institution_ids":["https://openalex.org/I4210165038"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11882","display_name":"Plant biochemistry and biosynthesis","score":0.6401000022888184,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11882","display_name":"Plant biochemistry and biosynthesis","score":0.6401000022888184,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11237","display_name":"Plant Gene Expression Analysis","score":0.34790000319480896,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12257","display_name":"Bioactive natural compounds","score":0.0035000001080334187,"subfield":{"id":"https://openalex.org/subfields/3002","display_name":"Drug Discovery"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[],"concepts":[{"id":"https://openalex.org/C2776085463","wikidata":"https://www.wikidata.org/wiki/Q7240581","display_name":"Prenyltransferase","level":4,"score":0.8867999911308289},{"id":"https://openalex.org/C2779054382","wikidata":"https://www.wikidata.org/wiki/Q72185287","display_name":"Flavonoid","level":3,"score":0.810699999332428},{"id":"https://openalex.org/C57790582","wikidata":"https://www.wikidata.org/wiki/Q901141","display_name":"Prenylation","level":3,"score":0.8066999912261963},{"id":"https://openalex.org/C2779655422","wikidata":"https://www.wikidata.org/wiki/Q1196166","display_name":"Glycyrrhiza uralensis","level":3,"score":0.7080000042915344},{"id":"https://openalex.org/C2780004758","wikidata":"https://www.wikidata.org/wiki/Q5458172","display_name":"Flavonoid biosynthesis","level":5,"score":0.623199999332428},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6029000282287598},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5577999949455261},{"id":"https://openalex.org/C553450214","wikidata":"https://www.wikidata.org/wiki/Q851162","display_name":"Biosynthesis","level":3,"score":0.5264999866485596},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.4519999921321869},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.44040000438690186},{"id":"https://openalex.org/C2778379183","wikidata":"https://www.wikidata.org/wiki/Q3234924","display_name":"Isoflavonoid","level":4,"score":0.40369999408721924},{"id":"https://openalex.org/C2777289219","wikidata":"https://www.wikidata.org/wiki/Q7632154","display_name":"Substrate (aquarium)","level":2,"score":0.4027000069618225},{"id":"https://openalex.org/C2778993495","wikidata":"https://www.wikidata.org/wiki/Q157830","display_name":"Glycyrrhiza","level":3,"score":0.40070000290870667},{"id":"https://openalex.org/C59759590","wikidata":"https://www.wikidata.org/wiki/Q2275927","display_name":"Regioselectivity","level":3,"score":0.3749000132083893},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.34610000252723694},{"id":"https://openalex.org/C93829228","wikidata":"https://www.wikidata.org/wiki/Q165963","display_name":"Plastid","level":4,"score":0.32199999690055847},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2703000009059906},{"id":"https://openalex.org/C193042331","wikidata":"https://www.wikidata.org/wiki/Q1772003","display_name":"Structure\u2013activity relationship","level":3,"score":0.2612999975681305},{"id":"https://openalex.org/C2781109383","wikidata":"https://www.wikidata.org/wiki/Q898497","display_name":"Hydroxylation","level":3,"score":0.2549999952316284},{"id":"https://openalex.org/C2780959689","wikidata":"https://www.wikidata.org/wiki/Q271943","display_name":"Isoprene","level":4,"score":0.2515000104904175}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1021/acs.jafc.6c11339","doi":"https://doi.org/10.1021/acs.jafc.6c11339","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acs.jafc.6c11339","pdf_url":null,"source":{"id":"https://openalex.org/S134644764","display_name":"Journal of Agricultural and Food Chemistry","issn_l":"0021-8561","issn":["0021-8561","1520-5118"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Agricultural and Food Chemistry","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":53,"referenced_works":["https://openalex.org/W2062034534","https://openalex.org/W2078521474","https://openalex.org/W2081102630","https://openalex.org/W2103378962","https://openalex.org/W2103956306","https://openalex.org/W2112480749","https://openalex.org/W2126481898","https://openalex.org/W2272144400","https://openalex.org/W2275074802","https://openalex.org/W2317609475","https://openalex.org/W2320310186","https://openalex.org/W2561803592","https://openalex.org/W2563335473","https://openalex.org/W2588052175","https://openalex.org/W2767615891","https://openalex.org/W2783075722","https://openalex.org/W2794327687","https://openalex.org/W2801867567","https://openalex.org/W2889360291","https://openalex.org/W2889988792","https://openalex.org/W2890106067","https://openalex.org/W2899439955","https://openalex.org/W2939399471","https://openalex.org/W2994337104","https://openalex.org/W3009104279","https://openalex.org/W3016628469","https://openalex.org/W3018326445","https://openalex.org/W3128061772","https://openalex.org/W3185891471","https://openalex.org/W3193781848","https://openalex.org/W3216174003","https://openalex.org/W4213367162","https://openalex.org/W4280523857","https://openalex.org/W4281965061","https://openalex.org/W4287577586","https://openalex.org/W4292483074","https://openalex.org/W4312186219","https://openalex.org/W4313650504","https://openalex.org/W4378714108","https://openalex.org/W4388967423","https://openalex.org/W4388968825","https://openalex.org/W4399940770","https://openalex.org/W4404058032","https://openalex.org/W4404252677","https://openalex.org/W4409542866","https://openalex.org/W4411326594","https://openalex.org/W4412580495","https://openalex.org/W4413024539","https://openalex.org/W4413357509","https://openalex.org/W4414135115","https://openalex.org/W7126425245","https://openalex.org/W7133525136","https://openalex.org/W7214202844"],"related_works":[],"abstract_inverted_index":{"Abstract":[0],"Species":[1],"of":[2,9,73,130,140],"Glycyrrhiza":[3,135],"(licorice)":[4],"produce":[5],"a":[6,85],"diverse":[7,74],"array":[8],"bioactive":[10],"prenylated":[11,131],"flavonoids.":[12],"Prenyltransferases":[13],"(PTs)":[14],"are":[15],"crucial":[16],"for":[17,88],"this":[18],"structural":[19],"diversification,":[20],"yet":[21],"their":[22],"diversity":[23],"and":[24,82,109,118],"functional":[25,122],"roles":[26],"in":[27,58,106],"licorice":[28],"remain":[29],"largely":[30],"unexplored.":[31],"Here,":[32],"we":[33],"identified":[34],"three":[35,47],"root-specific,":[36],"stress-induced":[37],"flavonoid":[38,141],"PT":[39],"candidates":[40],"(GgFPT1-3)":[41],"from":[42],"G.":[43,107,110],"glabra.":[44],"While":[45],"all":[46],"mainly":[48],"localized":[49],"to":[50],"the":[51,61,71,126,134],"chloroplast,":[52],"only":[53],"GgFPT3":[54,65],"exhibited":[55],"catalytic":[56],"activity":[57],"vitro":[59],"under":[60],"assay":[62],"conditions":[63],"tested.":[64],"demonstrated":[66],"remarkable":[67],"substrate":[68,119],"promiscuity,":[69],"catalyzing":[70],"monoprenylation":[72],"backbones":[75],"including":[76],"dihydroflavones,":[77],"isoflavans,":[78],"isoflavanones,":[79],"isoflavones,":[80],"chalcones,":[81],"pterocarpans,":[83],"with":[84,102],"regioselective":[86],"preference":[87],"B-ring":[89],"(e.g.,":[90],"C-3\u2032)":[91],"prenylation.":[92],"Intriguingly,":[93],"despite":[94],"sharing":[95],"high":[96],"amino":[97],"acid":[98],"sequence":[99],"identity":[100],"(>90%)":[101],"GgFPT3,":[103],"its":[104],"orthologs":[105],"inflata":[108],"uralensis":[111],"showed":[112],"distinct":[113],"expression":[114],"patterns,":[115],"enzymatic":[116],"activities,":[117],"preferences.":[120],"These":[121],"divergences":[123],"likely":[124],"underpin":[125],"species-specific":[127],"chemotypic":[128],"variations":[129],"flavonoids":[132],"across":[133],"genus,":[136],"expanding":[137],"our":[138],"understanding":[139],"diversification":[142],"mechanisms.":[143]},"counts_by_year":[],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2026-11-12T00:00:00"}