{"id":"https://openalex.org/W7225797031","doi":"https://doi.org/10.1021/acs.langmuir.6c05499","title":"Same Nanozyme, Different Rankings: A Critical Assessment and a Practical Reference Standard for Peroxidase-Mimicking Nanozymes","display_name":"Same Nanozyme, Different Rankings: A Critical Assessment and a Practical Reference Standard for Peroxidase-Mimicking Nanozymes","publication_year":2026,"publication_date":"2026-11-11","ids":{"openalex":"https://openalex.org/W7225797031","doi":"https://doi.org/10.1021/acs.langmuir.6c05499"},"language":"en","primary_location":{"id":"doi:10.1021/acs.langmuir.6c05499","doi":"https://doi.org/10.1021/acs.langmuir.6c05499","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acs.langmuir.6c05499","pdf_url":null,"source":{"id":"https://openalex.org/S75741262","display_name":"Langmuir","issn_l":"0743-7463","issn":["0743-7463","1520-5827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Langmuir","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090038703","display_name":"Vasily G. Panferov","orcid":"https://orcid.org/0000-0002-4057-7248","observed_orcids":["https://orcid.org/0000-0002-4057-7248"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210144344","display_name":"Federal Research Centre \u00abFundamentals of Biotechnology\u00bb of the Russian Academy of Sciences","ror":"https://ror.org/045sc8e83","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210129690","https://openalex.org/I4210144344"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Vasily G. Panferov","raw_affiliation_strings":["Research Center of Biotechnology of the Russian Academy of Sciences , , Leninsky Prospect 33 , ,"],"raw_orcid":"https://orcid.org/0000-0002-4057-7248","affiliations":[{"raw_affiliation_string":"Research Center of Biotechnology of the Russian Academy of Sciences , , Leninsky Prospect 33 , ,","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210144344"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101848814","display_name":"Xiangmei Li","orcid":"https://orcid.org/0000-0002-3871-8566","observed_orcids":["https://orcid.org/0000-0002-3871-8566"]},"institutions":[{"id":"https://openalex.org/I101479585","display_name":"South China Agricultural University","ror":"https://ror.org/05v9jqt67","country_code":"CN","type":"education","lineage":["https://openalex.org/I101479585"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiangmei Li","raw_affiliation_strings":["South China Agricultural University , , ,"],"raw_orcid":"https://orcid.org/0000-0002-3871-8566","affiliations":[{"raw_affiliation_string":"South China Agricultural University , , ,","institution_ids":["https://openalex.org/I101479585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052938214","display_name":"Anatoly Vitalievich Zherdev","orcid":"https://orcid.org/0000-0003-3008-2839","observed_orcids":["https://orcid.org/0000-0003-3008-2839"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210144344","display_name":"Federal Research Centre \u00abFundamentals of Biotechnology\u00bb of the Russian Academy of Sciences","ror":"https://ror.org/045sc8e83","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210129690","https://openalex.org/I4210144344"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Anatoly V. Zherdev","raw_affiliation_strings":["Research Center of Biotechnology of the Russian Academy of Sciences , , Leninsky Prospect 33 , ,"],"raw_orcid":"https://orcid.org/0000-0003-3008-2839","affiliations":[{"raw_affiliation_string":"Research Center of Biotechnology of the Russian Academy of Sciences , , Leninsky Prospect 33 , ,","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210144344"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041372701","display_name":"Boris Borisovich Dzantiev","orcid":"https://orcid.org/0000-0003-4008-4918","observed_orcids":["https://orcid.org/0000-0003-4008-4918"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210144344","display_name":"Federal Research Centre \u00abFundamentals of Biotechnology\u00bb of the Russian Academy of Sciences","ror":"https://ror.org/045sc8e83","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210129690","https://openalex.org/I4210144344"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Boris B. Dzantiev","raw_affiliation_strings":["Research Center of Biotechnology of the Russian Academy of Sciences , , Leninsky Prospect 33 , ,"],"raw_orcid":"https://orcid.org/0000-0003-4008-4918","affiliations":[{"raw_affiliation_string":"Research Center of Biotechnology of the Russian Academy of Sciences , , Leninsky Prospect 33 , ,","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210144344"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12302","display_name":"Advanced Nanomaterials in Catalysis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12302","display_name":"Advanced Nanomaterials in Catalysis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12240","display_name":"Nanomaterials for catalytic reactions","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[],"concepts":[{"id":"https://openalex.org/C136886441","wikidata":"https://www.wikidata.org/wiki/Q926129","display_name":"Normalization (sociology)","level":2,"score":0.781000018119812},{"id":"https://openalex.org/C86251818","wikidata":"https://www.wikidata.org/wiki/Q816754","display_name":"Benchmarking","level":2,"score":0.589900016784668},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.58160001039505},{"id":"https://openalex.org/C43411465","wikidata":"https://www.wikidata.org/wiki/Q2997621","display_name":"Bimetallic strip","level":3,"score":0.4440000057220459},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.3361000120639801},{"id":"https://openalex.org/C137535248","wikidata":"https://www.wikidata.org/wiki/Q4914691","display_name":"Bioanalysis","level":2,"score":0.2921000123023987},{"id":"https://openalex.org/C100253034","wikidata":"https://www.wikidata.org/wiki/Q196372","display_name":"Systematic error","level":2,"score":0.25769999623298645},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2538999915122986},{"id":"https://openalex.org/C3018395757","wikidata":"https://www.wikidata.org/wiki/Q1379672","display_name":"Evaluation methods","level":2,"score":0.2387000024318695},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.23469999432563782}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1021/acs.langmuir.6c05499","doi":"https://doi.org/10.1021/acs.langmuir.6c05499","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acs.langmuir.6c05499","pdf_url":null,"source":{"id":"https://openalex.org/S75741262","display_name":"Langmuir","issn_l":"0743-7463","issn":["0743-7463","1520-5827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Langmuir","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":57,"referenced_works":["https://openalex.org/W2098864517","https://openalex.org/W2170913114","https://openalex.org/W2560046754","https://openalex.org/W2574053842","https://openalex.org/W2737283327","https://openalex.org/W2750224611","https://openalex.org/W2766284936","https://openalex.org/W2810512849","https://openalex.org/W2949881242","https://openalex.org/W3015801401","https://openalex.org/W3122701408","https://openalex.org/W3157493048","https://openalex.org/W3195548726","https://openalex.org/W3202505378","https://openalex.org/W4210970969","https://openalex.org/W4212768989","https://openalex.org/W4220663118","https://openalex.org/W4229029291","https://openalex.org/W4297922206","https://openalex.org/W4308952511","https://openalex.org/W4319058068","https://openalex.org/W4321164681","https://openalex.org/W4360976126","https://openalex.org/W4366743024","https://openalex.org/W4382010759","https://openalex.org/W4382930845","https://openalex.org/W4385453601","https://openalex.org/W4386088445","https://openalex.org/W4393945007","https://openalex.org/W4396769975","https://openalex.org/W4400231019","https://openalex.org/W4401478672","https://openalex.org/W4401596146","https://openalex.org/W4402413443","https://openalex.org/W4402646575","https://openalex.org/W4404493660","https://openalex.org/W4405315749","https://openalex.org/W4407407469","https://openalex.org/W4407564697","https://openalex.org/W4408821712","https://openalex.org/W4409155011","https://openalex.org/W4410085127","https://openalex.org/W4410449343","https://openalex.org/W4412637094","https://openalex.org/W4413802451","https://openalex.org/W4413916474","https://openalex.org/W4414169066","https://openalex.org/W4415703722","https://openalex.org/W4415972032","https://openalex.org/W7118640874","https://openalex.org/W7151762291","https://openalex.org/W7154696822","https://openalex.org/W7165143229","https://openalex.org/W7165640545","https://openalex.org/W7166536763","https://openalex.org/W7204890079","https://openalex.org/W7212281891"],"related_works":[],"abstract_inverted_index":{"Abstract":[0],"Nanozymes":[1],"are":[2,116],"widely":[3],"investigated":[4],"as":[5,100],"stable":[6],"and":[7,36,87,93,111,120,129,155],"cost-effective":[8],"alternatives":[9],"to":[10,31,63,80,118,151],"natural":[11],"enzymes,":[12],"yet":[13],"their":[14],"quantitative":[15],"evaluation":[16],"remains":[17],"hindered":[18],"by":[19,61],"the":[20,38,48,71,152],"lack":[21],"of":[22,40,66,85],"standardized":[23],"metrics":[24],"for":[25,74,133,159],"catalytic":[26,162],"activity.":[27],"This":[28,68],"limitation":[29],"leads":[30],"inconsistent":[32],"comparisons":[33],"across":[34],"studies":[35],"impedes":[37],"assessment":[39],"structure\u2013activity":[41],"relationships.":[42],"Here,":[43],"we":[44,103,125],"demonstrate":[45],"that":[46,59],"using":[47],"same":[49],"experimental":[50],"data":[51],"set,":[52],"different":[53],"normalization":[54,107,146],"strategies":[55,108],"yield":[56],"turnover":[57],"numbers":[58],"vary":[60],"up":[62],"5":[64],"orders":[65],"magnitude.":[67],"finding":[69],"underscores":[70],"urgent":[72],"need":[73],"a":[75,127],"unified,":[76],"physically":[77],"consistent":[78,161],"approach":[79],"enable":[81],"meaningful":[82],"cross-study":[83],"benchmarking":[84],"nanozymes":[86,96],"enzymes.":[88],"Using":[89],"bimetallic":[90],"Au@Pt":[91],"core\u2013shell":[92],"trimetallic":[94],"Au@Ag\u2013Pt":[95],"with":[97],"surface-distributed":[98],"Pt":[99],"model":[101],"systems,":[102],"experimentally":[104],"validate":[105],"two":[106],"(per":[109],"particle":[110],"per":[112],"surface-accessible":[113],"atom),":[114],"which":[115],"relevant":[117],"bioanalytical":[119],"materials-design":[121],"applications,":[122],"respectively.":[123],"Furthermore,":[124],"propose":[126],"simple":[128],"reproducible":[130],"reference":[131],"standard":[132],"peroxidase":[134],"activity":[135],"based":[136],"on":[137],"Cu2+-mediated":[138],"TMB":[139],"oxidation.":[140],"Collectively,":[141],"these":[142],"results":[143],"clarify":[144],"how":[145],"strategy":[147],"should":[148],"be":[149],"matched":[150],"intended":[153],"application":[154],"provide":[156],"practical":[157],"tools":[158],"more":[160],"reporting.":[163]},"counts_by_year":[],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2026-11-12T00:00:00"}