{"id":"https://openalex.org/W7225794556","doi":"https://doi.org/10.1038/s41467-026-79063-x","title":"OsCPK17- and OsMPK6-mediated dual phosphorylation of OsPUB12 maintains OsPUB2-regulated OsPUB12 homeostasis and balances rice immunity","display_name":"OsCPK17- and OsMPK6-mediated dual phosphorylation of OsPUB12 maintains OsPUB2-regulated OsPUB12 homeostasis and balances rice immunity","publication_year":2026,"publication_date":"2026-11-11","ids":{"openalex":"https://openalex.org/W7225794556","doi":"https://doi.org/10.1038/s41467-026-79063-x"},"language":"en","primary_location":{"id":"doi:10.1038/s41467-026-79063-x","doi":"https://doi.org/10.1038/s41467-026-79063-x","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-026-79063-x","pdf_url":"https://www.nature.com/articles/s41467-026-79063-x_reference.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41467-026-79063-x_reference.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061769289","display_name":"Guosheng Zhao","orcid":"https://orcid.org/0000-0001-5439-4875","observed_orcids":["https://orcid.org/0000-0001-5439-4875"]},"institutions":[{"id":"https://openalex.org/I52158045","display_name":"China Agricultural University","ror":"https://ror.org/04v3ywz14","country_code":"CN","type":"education","lineage":["https://openalex.org/I52158045"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guosheng Zhao","raw_affiliation_strings":["State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China"],"raw_orcid":"https://orcid.org/0000-0001-5439-4875","affiliations":[{"raw_affiliation_string":"State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China","institution_ids":["https://openalex.org/I52158045"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014143927","display_name":"Baohui Mou","orcid":"https://orcid.org/0000-0002-5549-5712","observed_orcids":["https://orcid.org/0000-0002-5549-5712"]},"institutions":[{"id":"https://openalex.org/I52158045","display_name":"China Agricultural University","ror":"https://ror.org/04v3ywz14","country_code":"CN","type":"education","lineage":["https://openalex.org/I52158045"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Baohui Mou","raw_affiliation_strings":["State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China","institution_ids":["https://openalex.org/I52158045"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004083086","display_name":"Xinhang Zheng","orcid":"https://orcid.org/0000-0001-7714-5142","observed_orcids":["https://orcid.org/0000-0001-7714-5142"]},"institutions":[{"id":"https://openalex.org/I52158045","display_name":"China Agricultural University","ror":"https://ror.org/04v3ywz14","country_code":"CN","type":"education","lineage":["https://openalex.org/I52158045"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinhang Zheng","raw_affiliation_strings":["State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China","institution_ids":["https://openalex.org/I52158045"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161431380","display_name":"Shuo Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52158045","display_name":"China Agricultural University","ror":"https://ror.org/04v3ywz14","country_code":"CN","type":"education","lineage":["https://openalex.org/I52158045"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shuo Liu","raw_affiliation_strings":["State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China","institution_ids":["https://openalex.org/I52158045"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161439563","display_name":"Dian Sheng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52158045","display_name":"China Agricultural University","ror":"https://ror.org/04v3ywz14","country_code":"CN","type":"education","lineage":["https://openalex.org/I52158045"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dian Sheng","raw_affiliation_strings":["State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China","institution_ids":["https://openalex.org/I52158045"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030830611","display_name":"Shanzhi Wang","orcid":"https://orcid.org/0000-0002-8281-5013","observed_orcids":["https://orcid.org/0000-0002-8281-5013"]},"institutions":[{"id":"https://openalex.org/I142108993","display_name":"Southwest University","ror":"https://ror.org/01kj4z117","country_code":"CN","type":"education","lineage":["https://openalex.org/I142108993"]},{"id":"https://openalex.org/I52158045","display_name":"China Agricultural University","ror":"https://ror.org/04v3ywz14","country_code":"CN","type":"education","lineage":["https://openalex.org/I52158045"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shanzhi Wang","raw_affiliation_strings":["College of Plant Protection, Southwest University, Chongqing, China","State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Plant Protection, Southwest University, Chongqing, China","institution_ids":["https://openalex.org/I142108993"]},{"raw_affiliation_string":"State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China","institution_ids":["https://openalex.org/I52158045"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161464624","display_name":"Lin Zhu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52158045","display_name":"China Agricultural University","ror":"https://ror.org/04v3ywz14","country_code":"CN","type":"education","lineage":["https://openalex.org/I52158045"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lin Zhu","raw_affiliation_strings":["State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China","institution_ids":["https://openalex.org/I52158045"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5125016812","display_name":"Wu Yang","orcid":"https://orcid.org/0009-0002-7727-9348","observed_orcids":["https://orcid.org/0009-0002-7727-9348"]},"institutions":[{"id":"https://openalex.org/I52158045","display_name":"China Agricultural University","ror":"https://ror.org/04v3ywz14","country_code":"CN","type":"education","lineage":["https://openalex.org/I52158045"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wu Yang","raw_affiliation_strings":["State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China","institution_ids":["https://openalex.org/I52158045"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5140121613","display_name":"Zhicheng Huang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52158045","display_name":"China Agricultural University","ror":"https://ror.org/04v3ywz14","country_code":"CN","type":"education","lineage":["https://openalex.org/I52158045"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhicheng Huang","raw_affiliation_strings":["State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China","institution_ids":["https://openalex.org/I52158045"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101220263","display_name":"Song Shu","orcid":"https://orcid.org/0009-0008-5430-4719","observed_orcids":["https://orcid.org/0009-0008-5430-4719"]},"institutions":[{"id":"https://openalex.org/I52158045","display_name":"China Agricultural University","ror":"https://ror.org/04v3ywz14","country_code":"CN","type":"education","lineage":["https://openalex.org/I52158045"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shu Song","raw_affiliation_strings":["State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China","institution_ids":["https://openalex.org/I52158045"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058916981","display_name":"Songheng He","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52158045","display_name":"China Agricultural University","ror":"https://ror.org/04v3ywz14","country_code":"CN","type":"education","lineage":["https://openalex.org/I52158045"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Songheng He","raw_affiliation_strings":["State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China","institution_ids":["https://openalex.org/I52158045"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161448914","display_name":"Lisong Zhu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52158045","display_name":"China Agricultural University","ror":"https://ror.org/04v3ywz14","country_code":"CN","type":"education","lineage":["https://openalex.org/I52158045"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lisong Zhu","raw_affiliation_strings":["State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China","institution_ids":["https://openalex.org/I52158045"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077165956","display_name":"Yuese Ning","orcid":"https://orcid.org/0000-0003-1675-3114","observed_orcids":["https://orcid.org/0000-0003-1675-3114"]},"institutions":[{"id":"https://openalex.org/I4210097978","display_name":"Institute of Plant Protection","ror":"https://ror.org/0111f7045","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210097978","https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210138501","display_name":"Chinese Academy of Agricultural Sciences","ror":"https://ror.org/0313jb750","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4391767650","display_name":"State Key Laboratory of Biology of Plant Diseases and Insect Pests","ror":"https://ror.org/04bcwdq54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210097978","https://openalex.org/I4210127390","https://openalex.org/I4210138501","https://openalex.org/I4210151987","https://openalex.org/I4391767650"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuese Ning","raw_affiliation_strings":["State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, China"],"raw_orcid":"https://orcid.org/0000-0003-1675-3114","affiliations":[{"raw_affiliation_string":"State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210097978","https://openalex.org/I4210138501","https://openalex.org/I4391767650"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052829178","display_name":"Fuhao Cui","orcid":"https://orcid.org/0000-0001-8413-146X","observed_orcids":["https://orcid.org/0000-0001-8413-146X","https://orcid.org/0000-0001-6052-3629"]},"institutions":[{"id":"https://openalex.org/I52158045","display_name":"China Agricultural University","ror":"https://ror.org/04v3ywz14","country_code":"CN","type":"education","lineage":["https://openalex.org/I52158045"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fuhao Cui","raw_affiliation_strings":["State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China","institution_ids":["https://openalex.org/I52158045"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5127256325","display_name":"Jiyang Wang","orcid":"https://orcid.org/0000-0003-4781-3829","observed_orcids":["https://orcid.org/0000-0003-4781-3829"]},"institutions":[{"id":"https://openalex.org/I52158045","display_name":"China Agricultural University","ror":"https://ror.org/04v3ywz14","country_code":"CN","type":"education","lineage":["https://openalex.org/I52158045"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jiyang Wang","raw_affiliation_strings":["State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China"],"raw_orcid":"https://orcid.org/0000-0003-4781-3829","affiliations":[{"raw_affiliation_string":"State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China","institution_ids":["https://openalex.org/I52158045"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090362631","display_name":"Wenxian Sun","orcid":"https://orcid.org/0000-0001-6352-2461","observed_orcids":["https://orcid.org/0000-0001-6352-2461"]},"institutions":[{"id":"https://openalex.org/I4210152006","display_name":"Jilin Agricultural University","ror":"https://ror.org/05dmhhd41","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210152006"]},{"id":"https://openalex.org/I52158045","display_name":"China Agricultural University","ror":"https://ror.org/04v3ywz14","country_code":"CN","type":"education","lineage":["https://openalex.org/I52158045"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Wenxian Sun","raw_affiliation_strings":["College of Plant Protection, Jilin Agricultural University, Changchun, Jilin, China","State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China"],"raw_orcid":"https://orcid.org/0000-0001-6352-2461","affiliations":[{"raw_affiliation_string":"College of Plant Protection, Jilin Agricultural University, Changchun, Jilin, China","institution_ids":["https://openalex.org/I4210152006"]},{"raw_affiliation_string":"State Key Laboratory of Agricultural and Forestry Biosecurity, MARA Key Lab of Surveillance and Management for Plant Quarantine Pests, College of Plant Protection, China Agricultural University, Beijing, China","institution_ids":["https://openalex.org/I52158045"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5090362631","https://openalex.org/A5127256325"],"corresponding_institution_ids":["https://openalex.org/I4210152006","https://openalex.org/I52158045"],"apc_list":{"value":6990,"currency":"USD","value_usd":6990},"apc_paid":{"value":6990,"currency":"USD","value_usd":6990},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10076","display_name":"Plant-Microbe Interactions and Immunity","score":0.9556000232696533,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10076","display_name":"Plant-Microbe Interactions and Immunity","score":0.9556000232696533,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11041","display_name":"Ubiquitin and proteasome pathways","score":0.01810000091791153,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.0034000000450760126,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[],"concepts":[{"id":"https://openalex.org/C134459356","wikidata":"https://www.wikidata.org/wiki/Q4274835","display_name":"Ubiquitin ligase","level":4,"score":0.8467000126838684},{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.8342000246047974},{"id":"https://openalex.org/C25602115","wikidata":"https://www.wikidata.org/wiki/Q407111","display_name":"Ubiquitin","level":3,"score":0.7206000089645386},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6949999928474426},{"id":"https://openalex.org/C184235292","wikidata":"https://www.wikidata.org/wiki/Q421851","display_name":"Kinase","level":2,"score":0.6328999996185303},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5400999784469604},{"id":"https://openalex.org/C97029542","wikidata":"https://www.wikidata.org/wiki/Q281417","display_name":"Protein kinase A","level":3,"score":0.4309000074863434},{"id":"https://openalex.org/C2910050888","wikidata":"https://www.wikidata.org/wiki/Q4857068","display_name":"Protein-Serine-Threonine Kinases","level":4,"score":0.42500001192092896},{"id":"https://openalex.org/C87325107","wikidata":"https://www.wikidata.org/wiki/Q7251493","display_name":"Protein phosphorylation","level":4,"score":0.3986999988555908},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3977000117301941},{"id":"https://openalex.org/C2910254177","wikidata":"https://www.wikidata.org/wiki/Q4215946","display_name":"Plant Immunity","level":5,"score":0.3926999866962433},{"id":"https://openalex.org/C63645605","wikidata":"https://www.wikidata.org/wiki/Q103191","display_name":"Homeostasis","level":2,"score":0.38339999318122864},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.3797999918460846},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.34950000047683716},{"id":"https://openalex.org/C175114707","wikidata":"https://www.wikidata.org/wiki/Q408483","display_name":"DNA ligase","level":3,"score":0.3481000065803528},{"id":"https://openalex.org/C131312102","wikidata":"https://www.wikidata.org/wiki/Q5423632","display_name":"F-box protein","level":5,"score":0.33730000257492065},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3325999975204468},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.32829999923706055},{"id":"https://openalex.org/C165864922","wikidata":"https://www.wikidata.org/wiki/Q411391","display_name":"Regulation of gene expression","level":3,"score":0.3001999855041504},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2987000048160553},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.29600000381469727},{"id":"https://openalex.org/C2908868211","wikidata":"https://www.wikidata.org/wiki/Q4274835","display_name":"Ubiquitin-Protein Ligases","level":5,"score":0.28380000591278076},{"id":"https://openalex.org/C3019440502","wikidata":"https://www.wikidata.org/wiki/Q500430","display_name":"Dual role","level":2,"score":0.27459999918937683},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.26030001044273376},{"id":"https://openalex.org/C102658986","wikidata":"https://www.wikidata.org/wiki/Q5266092","display_name":"Deubiquitinating enzyme","level":4,"score":0.2540999948978424}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1038/s41467-026-79063-x","doi":"https://doi.org/10.1038/s41467-026-79063-x","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-026-79063-x","pdf_url":"https://www.nature.com/articles/s41467-026-79063-x_reference.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1038/s41467-026-79063-x","doi":"https://doi.org/10.1038/s41467-026-79063-x","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-026-79063-x","pdf_url":"https://www.nature.com/articles/s41467-026-79063-x_reference.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225794556.pdf","grobid_xml":"https://content.openalex.org/works/W7225794556.grobid-xml"},"referenced_works_count":37,"referenced_works":["https://openalex.org/W1821421562","https://openalex.org/W1965346708","https://openalex.org/W1997548626","https://openalex.org/W2021107644","https://openalex.org/W2030037724","https://openalex.org/W2057847071","https://openalex.org/W2112913709","https://openalex.org/W2114097399","https://openalex.org/W2124078282","https://openalex.org/W2131739069","https://openalex.org/W2137871007","https://openalex.org/W2162515800","https://openalex.org/W2766883163","https://openalex.org/W2774877825","https://openalex.org/W2791666936","https://openalex.org/W2799409697","https://openalex.org/W3135249221","https://openalex.org/W3139013939","https://openalex.org/W3190268827","https://openalex.org/W3200150398","https://openalex.org/W3201249440","https://openalex.org/W4214593312","https://openalex.org/W4281669937","https://openalex.org/W4285094726","https://openalex.org/W4296161596","https://openalex.org/W4312196006","https://openalex.org/W4383067567","https://openalex.org/W4387599086","https://openalex.org/W4391067408","https://openalex.org/W4396921189","https://openalex.org/W4402328503","https://openalex.org/W4406027976","https://openalex.org/W4409525614","https://openalex.org/W4412041485","https://openalex.org/W4414241045","https://openalex.org/W4414532807","https://openalex.org/W4414708605"],"related_works":[],"abstract_inverted_index":{"Numerous":[0],"E3":[1,15,31],"ubiquitin":[2,30],"ligases":[3,16],"regulate":[4,104],"plant":[5,33],"immunity":[6],"through":[7],"mediating":[8],"protein":[9,85],"homeostasis,":[10,141],"yet":[11],"how":[12],"homeostasis":[13],"of":[14,53,117,129,159],"is":[17],"finely":[18],"regulated":[19],"per":[20],"se":[21],"remains":[22],"poorly":[23],"understood.":[24],"Here,":[25],"we":[26],"reveal":[27],"that":[28,126],"the":[29,50,79,172],"ligase":[32],"U-box":[34],"2":[35],"(OsPUB2)":[36],"specifically":[37],"interacts":[38],"with":[39,107],"OsPUB12":[40,89,118,130,140,153,160],"and":[41,63,72,83,92,109,120,135,163,171],"targets":[42],"it":[43],"for":[44],"ubiquitin-mediated":[45],"degradation.":[46],"In":[47],"contrast":[48],"to":[49,59,65,114,147,154],"immunity-suppressing":[51],"role":[52],"OsPUB12,":[54],"OsPUB2":[55,108,151],"positively":[56],"regulates":[57],"resistance":[58],"rice":[60,121,149,156],"bacterial":[61],"diseases":[62],"contributes":[64],"pathogen-associated":[66],"molecular":[67],"pattern-induced":[68],"reactive":[69],"oxygen":[70],"burst":[71],"defense":[73,174],"gene":[74],"expression.":[75],"Upon":[76],"pathogen":[77],"challenge,":[78],"calcium-dependent":[80],"kinase":[81,86],"OsCPK17":[82,134,162],"mitogen-activated":[84],"OsMPK6":[87,136,164],"phosphorylate":[88],"at":[90,165],"Thr154":[91],"Ser460":[93],"in":[94],"a":[95,144],"temporally":[96],"sequential":[97],"manner.":[98],"These":[99],"two":[100,166],"phosphorylation":[101,128],"events":[102],"oppositely":[103],"OsPUB12\u2019s":[105],"interaction":[106],"its":[110,169],"subsequent":[111],"ubiquitination,":[112],"leading":[113],"divergent":[115],"regulation":[116],"stability":[119,170],"immunity.":[122,150,157],"Our":[123],"findings":[124],"indicate":[125],"distinct":[127],"by":[131,161],"immune-related":[132],"kinases":[133],"synergistically":[137],"maintains":[138],"OsPUB2-mediated":[139],"serving":[142],"as":[143],"core":[145],"mechanism":[146],"fine-tune":[148],"degrades":[152],"promote":[155],"Phosphorylation":[158],"sites":[167],"fine-tunes":[168],"plant\u2019s":[173],"response.":[175]},"counts_by_year":[],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2026-11-12T00:00:00"}
