{"id":"https://openalex.org/W7225775792","doi":"https://doi.org/10.1021/acsappcat.6c00172","title":"Small-Molecule-Catalyzed Late-Stage Aromatic Halogenation","display_name":"Small-Molecule-Catalyzed Late-Stage Aromatic Halogenation","publication_year":2026,"publication_date":"2026-11-11","ids":{"openalex":"https://openalex.org/W7225775792","doi":"https://doi.org/10.1021/acsappcat.6c00172"},"language":"en","primary_location":{"id":"doi:10.1021/acsappcat.6c00172","doi":"https://doi.org/10.1021/acsappcat.6c00172","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acsappcat.6c00172","pdf_url":null,"source":{"id":"https://openalex.org/S7407089858","display_name":"ACS Applied Catalysis","issn_l":"3071-4559","issn":["3071-4559"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACS Applied Catalysis","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101313791","display_name":"Ruilin Xu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruilin Xu","raw_affiliation_strings":["Peking University , , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Peking University , , ,","institution_ids":["https://openalex.org/I20231570"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161465706","display_name":"Hongwei Shi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hongwei Shi","raw_affiliation_strings":["Peking University , , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Peking University , , ,","institution_ids":["https://openalex.org/I20231570"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047717116","display_name":"Ning Jiao","orcid":"https://orcid.org/0000-0003-0290-9034","observed_orcids":["https://orcid.org/0000-0003-0290-9034"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4210153806","display_name":"Innovation and Technology Commission","ror":"https://ror.org/04vf9tr09","country_code":"HK","type":"government","lineage":["https://openalex.org/I4210153806"]}],"countries":["CN","HK"],"is_corresponding":false,"raw_author_name":"Ning Jiao","raw_affiliation_strings":["Chinese Academy of Sciences , , ,","Innovation and Technology Commission , , ,","Peking University , , ,"],"raw_orcid":"https://orcid.org/0000-0003-0290-9034","affiliations":[{"raw_affiliation_string":"Chinese Academy of Sciences , , ,","institution_ids":["https://openalex.org/I19820366"]},{"raw_affiliation_string":"Innovation and Technology Commission , , ,","institution_ids":["https://openalex.org/I4210153806"]},{"raw_affiliation_string":"Peking University , , ,","institution_ids":["https://openalex.org/I20231570"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10354","display_name":"Catalytic C\u2013H Functionalization Methods","score":0.9276999831199646,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10354","display_name":"Catalytic C\u2013H Functionalization Methods","score":0.9276999831199646,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11989","display_name":"Oxidative Organic Chemistry Reactions","score":0.03480000048875809,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12189","display_name":"Sulfur-Based Synthesis Techniques","score":0.006000000052154064,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[],"concepts":[{"id":"https://openalex.org/C65973085","wikidata":"https://www.wikidata.org/wiki/Q888529","display_name":"Halogenation","level":2,"score":0.9585000276565552},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.7508000135421753},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6345999836921692},{"id":"https://openalex.org/C40875361","wikidata":"https://www.wikidata.org/wiki/Q2356542","display_name":"Reagent","level":2,"score":0.498199999332428},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.44209998846054077},{"id":"https://openalex.org/C46062151","wikidata":"https://www.wikidata.org/wiki/Q19605","display_name":"Halogen","level":3,"score":0.42800000309944153},{"id":"https://openalex.org/C2777289219","wikidata":"https://www.wikidata.org/wiki/Q7632154","display_name":"Substrate (aquarium)","level":2,"score":0.41200000047683716},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.4034999907016754},{"id":"https://openalex.org/C148043351","wikidata":"https://www.wikidata.org/wiki/Q4456944","display_name":"Current (fluid)","level":2,"score":0.304500013589859},{"id":"https://openalex.org/C2991944050","wikidata":"https://www.wikidata.org/wiki/Q36534","display_name":"Reaction conditions","level":3,"score":0.2953999936580658},{"id":"https://openalex.org/C2779396153","wikidata":"https://www.wikidata.org/wiki/Q901227","display_name":"Natural product","level":2,"score":0.26600000262260437}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1021/acsappcat.6c00172","doi":"https://doi.org/10.1021/acsappcat.6c00172","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acsappcat.6c00172","pdf_url":null,"source":{"id":"https://openalex.org/S7407089858","display_name":"ACS Applied Catalysis","issn_l":"3071-4559","issn":["3071-4559"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACS Applied Catalysis","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":163,"referenced_works":["https://openalex.org/W1891046935","https://openalex.org/W1925851526","https://openalex.org/W1956858148","https://openalex.org/W1967335167","https://openalex.org/W1969914116","https://openalex.org/W1975355408","https://openalex.org/W1980544299","https://openalex.org/W1981569308","https://openalex.org/W1982346259","https://openalex.org/W1984963453","https://openalex.org/W1987793885","https://openalex.org/W1988331371","https://openalex.org/W1998312990","https://openalex.org/W2000951931","https://openalex.org/W2001086298","https://openalex.org/W2006683822","https://openalex.org/W2007778385","https://openalex.org/W2015981085","https://openalex.org/W2019052777","https://openalex.org/W2022926795","https://openalex.org/W2023832498","https://openalex.org/W2030557850","https://openalex.org/W2037956719","https://openalex.org/W2050848666","https://openalex.org/W2056215847","https://openalex.org/W2058895626","https://openalex.org/W2063335334","https://openalex.org/W2065970229","https://openalex.org/W2067433167","https://openalex.org/W2075514990","https://openalex.org/W2078574568","https://openalex.org/W2081318066","https://openalex.org/W2084667644","https://openalex.org/W2094065729","https://openalex.org/W2103513275","https://openalex.org/W2105058945","https://openalex.org/W2126443732","https://openalex.org/W2126756093","https://openalex.org/W2146070037","https://openalex.org/W2147816277","https://openalex.org/W2159649406","https://openalex.org/W2254913261","https://openalex.org/W2264994927","https://openalex.org/W2306548364","https://openalex.org/W2313164598","https://openalex.org/W2313432132","https://openalex.org/W2319035144","https://openalex.org/W2320440392","https://openalex.org/W2322047931","https://openalex.org/W2326890472","https://openalex.org/W2331612269","https://openalex.org/W2339051409","https://openalex.org/W2339265630","https://openalex.org/W2401448071","https://openalex.org/W2423348993","https://openalex.org/W2464706467","https://openalex.org/W2465690517","https://openalex.org/W2523431228","https://openalex.org/W2559579149","https://openalex.org/W2572897031","https://openalex.org/W2732259921","https://openalex.org/W2742701864","https://openalex.org/W2745154930","https://openalex.org/W2775976674","https://openalex.org/W2781102172","https://openalex.org/W2788241561","https://openalex.org/W2793556041","https://openalex.org/W2802989621","https://openalex.org/W2804393125","https://openalex.org/W2886231278","https://openalex.org/W2900745459","https://openalex.org/W2904662956","https://openalex.org/W2910924649","https://openalex.org/W2912550731","https://openalex.org/W2913365215","https://openalex.org/W2936743839","https://openalex.org/W2941934906","https://openalex.org/W2941988398","https://openalex.org/W2946891612","https://openalex.org/W2948327457","https://openalex.org/W2949129348","https://openalex.org/W2949233279","https://openalex.org/W2949928903","https://openalex.org/W2950947487","https://openalex.org/W2951322065","https://openalex.org/W2951505590","https://openalex.org/W2951915725","https://openalex.org/W2966004028","https://openalex.org/W2966669622","https://openalex.org/W2991644693","https://openalex.org/W2995419467","https://openalex.org/W2997316887","https://openalex.org/W3004939279","https://openalex.org/W3013828901","https://openalex.org/W3026023134","https://openalex.org/W3030507091","https://openalex.org/W3048947613","https://openalex.org/W3087817233","https://openalex.org/W3089947339","https://openalex.org/W3114791725","https://openalex.org/W3148021647","https://openalex.org/W3154542810","https://openalex.org/W3169624055","https://openalex.org/W3175397273","https://openalex.org/W3180015469","https://openalex.org/W3209139063","https://openalex.org/W3215003288","https://openalex.org/W4206108231","https://openalex.org/W4210810258","https://openalex.org/W4213362837","https://openalex.org/W4214921040","https://openalex.org/W4224074805","https://openalex.org/W4234330537","https://openalex.org/W4239121381","https://openalex.org/W4255210206","https://openalex.org/W4283026053","https://openalex.org/W4285590929","https://openalex.org/W4293812598","https://openalex.org/W4307405174","https://openalex.org/W4308994247","https://openalex.org/W4323825305","https://openalex.org/W4362596569","https://openalex.org/W4366779784","https://openalex.org/W4367596365","https://openalex.org/W4379616814","https://openalex.org/W4386469561","https://openalex.org/W4386593405","https://openalex.org/W4388410715","https://openalex.org/W4388462185","https://openalex.org/W4388792834","https://openalex.org/W4388871019","https://openalex.org/W4390465373","https://openalex.org/W4391285848","https://openalex.org/W4392125397","https://openalex.org/W4398140504","https://openalex.org/W4399388124","https://openalex.org/W4400640263","https://openalex.org/W4400889797","https://openalex.org/W4402667576","https://openalex.org/W4403052944","https://openalex.org/W4405355921","https://openalex.org/W4405810662","https://openalex.org/W4406775968","https://openalex.org/W4407322882","https://openalex.org/W4409122854","https://openalex.org/W4410221188","https://openalex.org/W4410515675","https://openalex.org/W4411005164","https://openalex.org/W4411261471","https://openalex.org/W4412872311","https://openalex.org/W4413099931","https://openalex.org/W4413420195","https://openalex.org/W4414608625","https://openalex.org/W4415913332","https://openalex.org/W4417029324","https://openalex.org/W4417230460","https://openalex.org/W7118172756","https://openalex.org/W7128006368","https://openalex.org/W7133363472","https://openalex.org/W7146947366","https://openalex.org/W7163132881","https://openalex.org/W7169881282","https://openalex.org/W7205010520"],"related_works":[],"abstract_inverted_index":{"Abstract":[0],"Halogen":[1],"atoms":[2],"are":[3,79,89],"widely":[4],"present":[5],"in":[6,38],"pharmaceuticals":[7],"and":[8,23,26,60,72,81,86],"natural":[9],"products.":[10],"Late-stage":[11],"C\u2013H":[12,41],"halogenation":[13,42,99],"of":[14,43,54,56,75,97],"complex":[15,44,101],"arenes":[16],"can":[17,27],"modulate":[18],"molecular":[19],"properties,":[20],"metabolic":[21],"stability,":[22],"biological":[24],"activity":[25],"provide":[28],"sites":[29],"for":[30],"further":[31],"derivatization.":[32],"This":[33],"Review":[34],"summarizes":[35],"recent":[36],"advances":[37],"small-molecule-catalyzed":[39],"late-stage":[40,98],"arenes.":[45],"The":[46,65],"discussion":[47],"is":[48],"organized":[49],"first":[50],"by":[51,62],"the":[52,57,95],"mode":[53],"activation":[55],"halogenating":[58],"reagent":[59],"then":[61],"catalyst":[63,68],"type.":[64],"reaction":[66],"characteristics,":[67],"design,":[69],"substrate":[70],"scope,":[71],"catalytic":[73,77],"mechanisms":[74],"different":[76],"systems":[78],"classified":[80],"compared.":[82],"Furthermore,":[83],"current":[84],"challenges":[85],"future":[87],"directions":[88],"also":[90],"discussed,":[91],"offering":[92],"insights":[93],"into":[94],"application":[96],"to":[100],"molecules.":[102]},"counts_by_year":[],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2026-11-12T00:00:00"}
