{"id":"https://openalex.org/W7225774308","doi":"https://doi.org/10.1186/s41935-026-00603-z","title":"The musculoskeletal phenotype of fatal strychnine poisoning","display_name":"The musculoskeletal phenotype of fatal strychnine poisoning","publication_year":2026,"publication_date":"2026-11-12","ids":{"openalex":"https://openalex.org/W7225774308","doi":"https://doi.org/10.1186/s41935-026-00603-z"},"language":"en","primary_location":{"id":"doi:10.1186/s41935-026-00603-z","doi":"https://doi.org/10.1186/s41935-026-00603-z","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s41935-026-00603-z","pdf_url":null,"source":{"id":"https://openalex.org/S2764591111","display_name":"Egyptian Journal of Forensic Sciences","issn_l":"2090-536X","issn":["2090-536X","2090-5939"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Egyptian Journal of Forensic Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.1186/s41935-026-00603-z","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065619461","display_name":"Raffaella Vetrini","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Raffaella Vetrini","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005876871","display_name":"Emiliana Giacomello","orcid":"https://orcid.org/0000-0003-3329-6269","observed_orcids":["https://orcid.org/0000-0003-3329-6269"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Emiliana Giacomello","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3329-6269","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085143808","display_name":"Calogero Cuttaia","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Calogero Cuttaia","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161482355","display_name":"Michela Tracanelli","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michela Tracanelli","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075913569","display_name":"Riccardo Addobbati","orcid":"https://orcid.org/0000-0002-8833-1511","observed_orcids":["https://orcid.org/0000-0002-8833-1511"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Riccardo Addobbati","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161451487","display_name":"Luana Toniolo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Luana Toniolo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047269369","display_name":"Emina Dervi\u0161evi\u0107","orcid":"https://orcid.org/0000-0002-9673-4820","observed_orcids":["https://orcid.org/0000-0002-9673-4820","https://orcid.org/0000-0001-8429-0508"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Emina Spahic Dervisevic","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9673-4820","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5120211745","display_name":"Amina Zorlak-\u010cav\u010di\u0107","orcid":"https://orcid.org/0009-0006-8006-5243","observed_orcids":["https://orcid.org/0009-0006-8006-5243"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Amina Zorlak-Cavcic","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5076248582","display_name":"Stefano D\u2019Errico","orcid":"https://orcid.org/0000-0003-3689-0001","observed_orcids":["https://orcid.org/0000-0003-3689-0001"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D\u2019Errico Stefano","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3689-0001","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":0,"currency":"USD","value_usd":0},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"16","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10800","display_name":"Forensic Toxicology and Drug Analysis","score":0.8798999786376953,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10800","display_name":"Forensic Toxicology and Drug Analysis","score":0.8798999786376953,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14199","display_name":"Historical and Scientific Studies","score":0.040300000458955765,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13001","display_name":"Restraint-Related Deaths","score":0.025499999523162842,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[],"concepts":[{"id":"https://openalex.org/C37999436","wikidata":"https://www.wikidata.org/wiki/Q274095","display_name":"Rigor mortis","level":2,"score":0.8944000005722046},{"id":"https://openalex.org/C2777725853","wikidata":"https://www.wikidata.org/wiki/Q194406","display_name":"Strychnine","level":2,"score":0.8931000232696533},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6220999956130981},{"id":"https://openalex.org/C2779504383","wikidata":"https://www.wikidata.org/wiki/Q41482","display_name":"Autopsy","level":2,"score":0.6141999959945679},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.44620001316070557},{"id":"https://openalex.org/C2779959927","wikidata":"https://www.wikidata.org/wiki/Q1048687","display_name":"Skeletal muscle","level":2,"score":0.4253999888896942},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.39100000262260437},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.38019999861717224},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.3756999969482422},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.35440000891685486},{"id":"https://openalex.org/C3017944768","wikidata":"https://www.wikidata.org/wiki/Q1450463","display_name":"Poison control","level":2,"score":0.3208000063896179},{"id":"https://openalex.org/C2991992180","wikidata":"https://www.wikidata.org/wiki/Q16938214","display_name":"Time of death","level":2,"score":0.29660001397132874},{"id":"https://openalex.org/C164292776","wikidata":"https://www.wikidata.org/wiki/Q5271779","display_name":"Diaphragm (acoustics)","level":3,"score":0.296099990606308},{"id":"https://openalex.org/C2779071755","wikidata":"https://www.wikidata.org/wiki/Q21685486","display_name":"Forensic pathology","level":3,"score":0.2840999960899353},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.27709999680519104},{"id":"https://openalex.org/C2777756961","wikidata":"https://www.wikidata.org/wiki/Q620730","display_name":"Glycine","level":3,"score":0.275299996137619},{"id":"https://openalex.org/C2776860028","wikidata":"https://www.wikidata.org/wiki/Q1225289","display_name":"Muscle relaxant","level":2,"score":0.25290000438690186}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1186/s41935-026-00603-z","doi":"https://doi.org/10.1186/s41935-026-00603-z","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s41935-026-00603-z","pdf_url":null,"source":{"id":"https://openalex.org/S2764591111","display_name":"Egyptian Journal of Forensic Sciences","issn_l":"2090-536X","issn":["2090-536X","2090-5939"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Egyptian Journal of Forensic Sciences","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1186/s41935-026-00603-z","doi":"https://doi.org/10.1186/s41935-026-00603-z","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s41935-026-00603-z","pdf_url":null,"source":{"id":"https://openalex.org/S2764591111","display_name":"Egyptian Journal of Forensic Sciences","issn_l":"2090-536X","issn":["2090-536X","2090-5939"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Egyptian Journal of Forensic Sciences","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W1533653398","https://openalex.org/W1799879229","https://openalex.org/W2026618396","https://openalex.org/W2031722664","https://openalex.org/W2051118924","https://openalex.org/W2055801044","https://openalex.org/W2081597011","https://openalex.org/W2081834777","https://openalex.org/W2102912656","https://openalex.org/W2111202057","https://openalex.org/W2117076174","https://openalex.org/W2120331067","https://openalex.org/W2130025116","https://openalex.org/W2149189574","https://openalex.org/W2296354318","https://openalex.org/W2489428749","https://openalex.org/W2552341113","https://openalex.org/W2953305163","https://openalex.org/W3210267220","https://openalex.org/W4230639967","https://openalex.org/W4237040742","https://openalex.org/W4240823940","https://openalex.org/W4246265356","https://openalex.org/W4387246415","https://openalex.org/W4389343129","https://openalex.org/W4390762257","https://openalex.org/W4405028466","https://openalex.org/W7118080263","https://openalex.org/W7161068040"],"related_works":[],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"Strychnine":[2,12,46],"poisoning":[3,47,287,311],"is":[4,13,74,134],"still":[5],"a":[6,14,162,166,175,293],"documented":[7],"entity":[8],"in":[9,29,273],"forensic":[10],"medicine.":[11],"competitor":[15],"of":[16,24,57,69,86,90,95,116,126,129,137,140,165,174,178,183,229,248,269,285,298,316,354,364],"the":[17,22,30,88,93,105,113,124,127,138,172,181,184,207,209,214,226,233,236,241,258,283,299,314,329,347,352],"post-synaptic":[18,39],"glycine":[19,35],"receptors":[20],"at":[21,92],"level":[23,94],"motor":[25],"neurons":[26,40],"and":[27,62,79,104,131,144,192,240,255,278,295,301,322,360,369],"interneurons":[28],"spinal":[31],"cord,":[32],"which":[33,149],"blocks":[34],"inhibitory":[36],"effects":[37,128],"on":[38,118,213,257,351,356,367],"leading":[41],"to":[42,67,111,154,288],"involuntary":[43],"muscle":[44,60,97,142,332,358],"contractions.":[45],"appears":[48],"with":[49,59,225,251,319,338,341],"an":[50],"initial":[51],"excitability,":[52],"followed":[53],"by":[54],"vomiting,":[55],"development":[56],"convulsions,":[58],"contractions,":[61],"can":[63],"result":[64],"fatal":[65],"due":[66],"spasm":[68],"respiratory":[70,81,289,331],"muscles.":[71,304,372],"Although":[72],"it":[73,264],"widely":[75],"accepted":[76],"that":[77,266,309],"diaphragm":[78,300,317,368],"accessory":[80,330],"muscles":[82,120,290],"are":[83],"primarily":[84],"responsible":[85],"death,":[87],"impact":[89,284,353],"strychnine":[91,117,130,270,286,310,355],"skeletal":[96,119,141,357],"fibers":[98,143,324,340],"morphology":[99,315],"has":[100],"been":[101],"poorly":[102],"investigated,":[103],"literature":[106],"does":[107],"not":[108],"report":[109,161],"evidence":[110],"understand":[112],"precise":[114],"effect":[115],"cytological":[121],"organization.":[122],"Indeed,":[123],"study":[125],"other":[132],"poisons":[133],"challenging":[135],"because":[136],"heterogeneity":[139],"their":[145],"distinct":[146,362],"physiological":[147],"properties,":[148],"could":[150],"determine":[151],"different":[152],"responses":[153],"each":[155],"toxic":[156],"substance.":[157],"Case":[158],"presentation":[159],"We":[160],"suicidal":[163],"case":[164],"50-year-old":[167],"man":[168],"who":[169],"died":[170],"following":[171],"ingestion":[173],"lethal":[176],"dose":[177],"strychnine.":[179],"At":[180],"time":[182,208],"crime":[185,237],"scene":[186,238],"examination,":[187],"rigor":[188,217,230],"mortis":[189,218,231],"was":[190,200,211,223],"present":[191,272],"fully":[193],"established.":[194],"A":[195],"complete":[196],"post":[197],"mortem":[198],"examination":[199,239,245],"performed":[201,292],"few":[202],"days":[203],"after":[204],"death.":[205],"By":[206],"body":[210],"examined":[212],"autopsy":[215,244],"table,":[216],"had":[219],"already":[220],"resolved.":[221],"This":[222,344],"consistent":[224],"expected":[227],"evolution":[228],"over":[232],"interval":[234],"between":[235],"autopsy.":[242],"The":[243],"revealed":[246],"enlargement":[247],"both":[249,320],"lungs":[250],"abundant":[252],"blood-tinged":[253],"fluid":[254],"foam":[256],"main":[259],"bronchi.":[260],"From":[261],"toxicological":[262],"analyses,":[263],"emerged":[265],"massive":[267],"concentrations":[268],"were":[271],"peripheral":[274],"blood,":[275],"gastric":[276],"contents":[277],"vitreous":[279],"humor.":[280],"To":[281],"comprehend":[282],"we":[291],"morphological":[294],"immunofluorescence":[296],"characterization":[297],"pectoralis":[302,333,370],"major":[303,334,371],"Conclusions":[305],"Our":[306],"observations":[307],"suggest":[308],"profoundly":[312],"impacts":[313],"fibers,":[318,359],"fast":[321],"slow":[323],"presenting":[325],"hypercontraction":[326,342],"areas.":[327,343],"While":[328],"presents":[335],"milder":[336],"alterations,":[337],"fewer":[339],"work":[345],"represents":[346],"first":[348],"histological":[349],"investigation":[350],"suggests":[361],"influence":[363],"this":[365],"poison":[366]},"counts_by_year":[],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2026-11-12T00:00:00"}