{"id":"https://openalex.org/W7225748145","doi":"https://doi.org/10.1038/s41564-026-02426-z","title":"Env-specific antibodies promote post-treatment control in SIV-infected macaques","display_name":"Env-specific antibodies promote post-treatment control in SIV-infected macaques","publication_year":2026,"publication_date":"2026-11-10","ids":{"openalex":"https://openalex.org/W7225748145","doi":"https://doi.org/10.1038/s41564-026-02426-z"},"language":"en","primary_location":{"id":"doi:10.1038/s41564-026-02426-z","doi":"https://doi.org/10.1038/s41564-026-02426-z","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41564-026-02426-z","pdf_url":null,"source":{"id":"https://openalex.org/S2764926557","display_name":"Nature Microbiology","issn_l":"2058-5276","issn":["2058-5276"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Microbiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1038/s41564-026-02426-z","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103253562","display_name":"Vidisha Singh","orcid":"https://orcid.org/0000-0002-8942-519X","observed_orcids":["https://orcid.org/0000-0002-8942-519X"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vidisha Singh","raw_affiliation_strings":["Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5124198658","display_name":"Divine Burgess","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Divine Burgess","raw_affiliation_strings":["Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092985310","display_name":"Jordan N. Goldy","orcid":"https://orcid.org/0000-0001-8803-8713","observed_orcids":["https://orcid.org/0000-0001-8803-8713"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jordan Goldy","raw_affiliation_strings":["Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004707597","display_name":"Amir Dashti","orcid":"https://orcid.org/0000-0002-4679-7962","observed_orcids":["https://orcid.org/0000-0002-4679-7962"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amir Dashti","raw_affiliation_strings":["Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161407692","display_name":"Hannah King","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]},{"id":"https://openalex.org/I4405268911","display_name":"Vaccine Research Center","ror":"https://ror.org/02fve6a73","country_code":"US","type":"facility","lineage":["https://openalex.org/I4405268911"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hannah King","raw_affiliation_strings":["Vaccine Research Center, NIAID, NIH, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vaccine Research Center, NIAID, NIH, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210134534","https://openalex.org/I4405268911"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041766995","display_name":"Emily J. Fray","orcid":"https://orcid.org/0000-0002-5850-6237","observed_orcids":["https://orcid.org/0000-0002-5850-6237"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Emily Fray","raw_affiliation_strings":["Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA"],"raw_orcid":"https://orcid.org/0000-0002-5850-6237","affiliations":[{"raw_affiliation_string":"Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065362348","display_name":"Anushka Singhal","orcid":"https://orcid.org/0009-0000-7001-3366","observed_orcids":["https://orcid.org/0009-0000-7001-3366","https://orcid.org/0009-0004-4572-6697"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anushka Singhal","raw_affiliation_strings":["Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038532038","display_name":"Maud Mavigner","orcid":"https://orcid.org/0000-0001-9898-317X","observed_orcids":["https://orcid.org/0000-0001-9898-317X"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I4210146983","display_name":"Children's Healthcare of Atlanta","ror":"https://ror.org/050fhx250","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210146983"]},{"id":"https://openalex.org/I4392738091","display_name":"Emory National Primate Research Center","ror":"https://ror.org/038kr2d80","country_code":"US","type":"facility","lineage":["https://openalex.org/I150468666","https://openalex.org/I4392738091"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maud Mavigner","raw_affiliation_strings":["Center for Childhood Infections and Vaccines, Children\u2019s Heathcare of Atlanta and Emory University, Atlanta, GA, USA","Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA","Emory National Primate Research Center, Emory University, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Childhood Infections and Vaccines, Children\u2019s Heathcare of Atlanta and Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666","https://openalex.org/I4210146983"]},{"raw_affiliation_string":"Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Emory National Primate Research Center, Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666","https://openalex.org/I4392738091"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103185693","display_name":"Nils Schoof","orcid":"https://orcid.org/0000-0003-0343-2776","observed_orcids":["https://orcid.org/0000-0003-0343-2776"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nils Schoof","raw_affiliation_strings":["Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114087279","display_name":"Zain Siddiqi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zain Siddiqi","raw_affiliation_strings":["Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA"],"raw_orcid":"https://orcid.org/0009-0006-9646-760X","affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013279511","display_name":"Rosemarie D. Mason","orcid":"https://orcid.org/0000-0001-7123-4902","observed_orcids":["https://orcid.org/0000-0001-7123-4902"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]},{"id":"https://openalex.org/I4405268911","display_name":"Vaccine Research Center","ror":"https://ror.org/02fve6a73","country_code":"US","type":"facility","lineage":["https://openalex.org/I4405268911"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rosemarie D. Mason","raw_affiliation_strings":["Vaccine Research Center, NIAID, NIH, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vaccine Research Center, NIAID, NIH, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210134534","https://openalex.org/I4405268911"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028012551","display_name":"Jeffrey T. Safrit","orcid":"https://orcid.org/0000-0001-7441-4423","observed_orcids":["https://orcid.org/0000-0001-7441-4423"]},"institutions":[{"id":"https://openalex.org/I4210144466","display_name":"ImmunityBio (United States)","ror":"https://ror.org/04090g527","country_code":"US","type":"company","lineage":["https://openalex.org/I4210144466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey T. Safrit","raw_affiliation_strings":["ImmunityBio, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ImmunityBio, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I4210144466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011287791","display_name":"Vinh B. Dinh","orcid":"https://orcid.org/0000-0002-8148-8508","observed_orcids":["https://orcid.org/0000-0002-8148-8508"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vinh Dinh","raw_affiliation_strings":["Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058858155","display_name":"Deanna A. Kulpa","orcid":"https://orcid.org/0000-0002-0411-7295","observed_orcids":["https://orcid.org/0000-0002-0411-7295"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I4392738091","display_name":"Emory National Primate Research Center","ror":"https://ror.org/038kr2d80","country_code":"US","type":"facility","lineage":["https://openalex.org/I150468666","https://openalex.org/I4392738091"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Deanna Kulpa","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA","Emory National Primate Research Center, Emory University, Atlanta, GA, USA"],"raw_orcid":"https://orcid.org/0000-0002-0411-7295","affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Emory National Primate Research Center, Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666","https://openalex.org/I4392738091"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040099496","display_name":"Rafick\u2010Pierre S\u00e9kaly","orcid":"https://orcid.org/0000-0002-7816-4828","observed_orcids":["https://orcid.org/0000-0002-7816-4828"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rafick-Pierre S\u00e9kaly","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA","Emory Vaccine Center, Emory University, Atlanta, GA, USA"],"raw_orcid":"https://orcid.org/0000-0002-7816-4828","affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Emory Vaccine Center, Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059304714","display_name":"Mirko Paiardini","orcid":"https://orcid.org/0000-0002-7276-3600","observed_orcids":["https://orcid.org/0000-0002-7276-3600"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I4392738091","display_name":"Emory National Primate Research Center","ror":"https://ror.org/038kr2d80","country_code":"US","type":"facility","lineage":["https://openalex.org/I150468666","https://openalex.org/I4392738091"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mirko Paiardini","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA","Emory National Primate Research Center, Emory University, Atlanta, GA, USA","Emory Vaccine Center, Emory University, Atlanta, GA, USA"],"raw_orcid":"https://orcid.org/0000-0002-7276-3600","affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Emory National Primate Research Center, Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666","https://openalex.org/I4392738091"]},{"raw_affiliation_string":"Emory Vaccine Center, Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043225490","display_name":"Jeffrey D. Lifson","orcid":"https://orcid.org/0000-0002-9494-0268","observed_orcids":["https://orcid.org/0000-0002-9494-0268"]},"institutions":[{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4396570585","display_name":"Leidos Biomedical Research Inc. (United States)","ror":"https://ror.org/00bardy64","country_code":"US","type":"company","lineage":["https://openalex.org/I114662689","https://openalex.org/I4396570585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey D. Lifson","raw_affiliation_strings":["AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD, USA"],"raw_orcid":"https://orcid.org/0000-0002-9494-0268","affiliations":[{"raw_affiliation_string":"AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD, USA","institution_ids":["https://openalex.org/I4210130649","https://openalex.org/I4396570585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079324608","display_name":"Robert F. Siliciano","orcid":"https://orcid.org/0000-0002-1764-1993","observed_orcids":["https://orcid.org/0000-0002-1764-1993"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert F. Siliciano","raw_affiliation_strings":["Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA"],"raw_orcid":"https://orcid.org/0000-0002-1764-1993","affiliations":[{"raw_affiliation_string":"Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014454124","display_name":"Janet D'Angelo Siliciano","orcid":"https://orcid.org/0000-0001-6712-3775","observed_orcids":["https://orcid.org/0000-0001-6712-3775"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Janet D. Siliciano","raw_affiliation_strings":["Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA"],"raw_orcid":"https://orcid.org/0000-0001-6712-3775","affiliations":[{"raw_affiliation_string":"Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090939942","display_name":"Mario Roederer","orcid":"https://orcid.org/0000-0001-7448-7040","observed_orcids":["https://orcid.org/0000-0001-7448-7040"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]},{"id":"https://openalex.org/I4405268911","display_name":"Vaccine Research Center","ror":"https://ror.org/02fve6a73","country_code":"US","type":"facility","lineage":["https://openalex.org/I4405268911"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mario Roederer","raw_affiliation_strings":["Vaccine Research Center, NIAID, NIH, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vaccine Research Center, NIAID, NIH, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210134534","https://openalex.org/I4405268911"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036830739","display_name":"Ashish Sharma","orcid":"https://orcid.org/0000-0001-9444-7046","observed_orcids":["https://orcid.org/0000-0001-9444-7046"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ashish Sharma","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA"],"raw_orcid":"https://orcid.org/0000-0001-9444-7046","affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074424857","display_name":"Guido Silvestri","orcid":"https://orcid.org/0000-0001-6602-2470","observed_orcids":["https://orcid.org/0000-0001-6602-2470","https://orcid.org/0000-0001-5505-7467"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I4392738091","display_name":"Emory National Primate Research Center","ror":"https://ror.org/038kr2d80","country_code":"US","type":"facility","lineage":["https://openalex.org/I150468666","https://openalex.org/I4392738091"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Guido Silvestri","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA","Emory National Primate Research Center, Emory University, Atlanta, GA, USA","Emory Vaccine Center, Emory University, Atlanta, GA, USA"],"raw_orcid":"https://orcid.org/0000-0001-6602-2470","affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Emory National Primate Research Center, Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666","https://openalex.org/I4392738091"]},{"raw_affiliation_string":"Emory Vaccine Center, Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075577675","display_name":"Ann Chahroudi","orcid":"https://orcid.org/0000-0001-7479-9546","observed_orcids":["https://orcid.org/0000-0001-7479-9546"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I4210146983","display_name":"Children's Healthcare of Atlanta","ror":"https://ror.org/050fhx250","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210146983"]},{"id":"https://openalex.org/I4392738091","display_name":"Emory National Primate Research Center","ror":"https://ror.org/038kr2d80","country_code":"US","type":"facility","lineage":["https://openalex.org/I150468666","https://openalex.org/I4392738091"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Ann Chahroudi","raw_affiliation_strings":["Center for Childhood Infections and Vaccines, Children\u2019s Heathcare of Atlanta and Emory University, Atlanta, GA, USA","Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA","Emory National Primate Research Center, Emory University, Atlanta, GA, USA","Emory Vaccine Center, Emory University, Atlanta, GA, USA"],"raw_orcid":"https://orcid.org/0000-0001-7479-9546","affiliations":[{"raw_affiliation_string":"Center for Childhood Infections and Vaccines, Children\u2019s Heathcare of Atlanta and Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666","https://openalex.org/I4210146983"]},{"raw_affiliation_string":"Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Emory National Primate Research Center, Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666","https://openalex.org/I4392738091"]},{"raw_affiliation_string":"Emory Vaccine Center, Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5074424857","https://openalex.org/A5075577675"],"corresponding_institution_ids":["https://openalex.org/I150468666","https://openalex.org/I4210146983","https://openalex.org/I4392738091"],"apc_list":{"value":12690,"currency":"USD","value_usd":12690},"apc_paid":{"value":12690,"currency":"USD","value_usd":12690},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11381","display_name":"Infectious Diseases and Tuberculosis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[],"concepts":[{"id":"https://openalex.org/C2777995582","wikidata":"https://www.wikidata.org/wiki/Q1890246","display_name":"Simian immunodeficiency virus","level":3,"score":0.8978999853134155},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.7279999852180481},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.6682999730110168},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.6298999786376953},{"id":"https://openalex.org/C82876162","wikidata":"https://www.wikidata.org/wiki/Q17096504","display_name":"Latency (audio)","level":2,"score":0.6227999925613403},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.6039999723434448},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5839999914169312},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5647000074386597},{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.5396999716758728},{"id":"https://openalex.org/C2779175743","wikidata":"https://www.wikidata.org/wiki/Q156606","display_name":"Rhesus macaque","level":2,"score":0.4916999936103821},{"id":"https://openalex.org/C2779690655","wikidata":"https://www.wikidata.org/wiki/Q374232","display_name":"Lentivirus","level":4,"score":0.46369999647140503},{"id":"https://openalex.org/C2776178377","wikidata":"https://www.wikidata.org/wiki/Q188269","display_name":"Interferon","level":2,"score":0.4165000021457672},{"id":"https://openalex.org/C2776315342","wikidata":"https://www.wikidata.org/wiki/Q21105865","display_name":"SAMHD1","level":5,"score":0.3840000033378601},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.3765999972820282},{"id":"https://openalex.org/C2777607303","wikidata":"https://www.wikidata.org/wiki/Q641307","display_name":"Immunodeficiency","level":3,"score":0.36980000138282776},{"id":"https://openalex.org/C2778950215","wikidata":"https://www.wikidata.org/wiki/Q177601","display_name":"Macaque","level":2,"score":0.3598000109195709},{"id":"https://openalex.org/C2776488936","wikidata":"https://www.wikidata.org/wiki/Q5452918","display_name":"Simian","level":3,"score":0.3402000069618225},{"id":"https://openalex.org/C2780509455","wikidata":"https://www.wikidata.org/wiki/Q7380","display_name":"Primate","level":2,"score":0.33079999685287476},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.3260999917984009},{"id":"https://openalex.org/C140206745","wikidata":"https://www.wikidata.org/wiki/Q5308895","display_name":"Drug holiday","level":3,"score":0.3246000111103058},{"id":"https://openalex.org/C140704245","wikidata":"https://www.wikidata.org/wiki/Q3933202","display_name":"Viral replication","level":3,"score":0.32249999046325684},{"id":"https://openalex.org/C2780727368","wikidata":"https://www.wikidata.org/wiki/Q1928978","display_name":"Viral disease","level":3,"score":0.3100000023841858},{"id":"https://openalex.org/C2777761686","wikidata":"https://www.wikidata.org/wiki/Q715347","display_name":"Lymphocyte","level":2,"score":0.30660000443458557},{"id":"https://openalex.org/C58475186","wikidata":"https://www.wikidata.org/wiki/Q4118894","display_name":"Viral entry","level":4,"score":0.3046000003814697},{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.29660001397132874},{"id":"https://openalex.org/C2780879997","wikidata":"https://www.wikidata.org/wiki/Q952587","display_name":"Viral protein","level":3,"score":0.2964000105857849},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.2921999990940094},{"id":"https://openalex.org/C163864487","wikidata":"https://www.wikidata.org/wiki/Q6901461","display_name":"Monoclonal","level":4,"score":0.2890999913215637},{"id":"https://openalex.org/C2778852064","wikidata":"https://www.wikidata.org/wiki/Q4115619","display_name":"Virus latency","level":4,"score":0.28850001096725464},{"id":"https://openalex.org/C2993143319","wikidata":"https://www.wikidata.org/wiki/Q583050","display_name":"Antiretroviral therapy","level":4,"score":0.2858999967575073},{"id":"https://openalex.org/C2777470312","wikidata":"https://www.wikidata.org/wiki/Q82261","display_name":"Haplorhini","level":3,"score":0.2728999853134155},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.2727999985218048},{"id":"https://openalex.org/C2992881475","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T lymphocyte","level":3,"score":0.2703000009059906},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.26820001006126404},{"id":"https://openalex.org/C12914427","wikidata":"https://www.wikidata.org/wiki/Q7933612","display_name":"Viral shedding","level":3,"score":0.26179999113082886}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1038/s41564-026-02426-z","doi":"https://doi.org/10.1038/s41564-026-02426-z","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41564-026-02426-z","pdf_url":null,"source":{"id":"https://openalex.org/S2764926557","display_name":"Nature Microbiology","issn_l":"2058-5276","issn":["2058-5276"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Microbiology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1038/s41564-026-02426-z","doi":"https://doi.org/10.1038/s41564-026-02426-z","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41564-026-02426-z","pdf_url":null,"source":{"id":"https://openalex.org/S2764926557","display_name":"Nature Microbiology","issn_l":"2058-5276","issn":["2058-5276"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Microbiology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":46,"referenced_works":["https://openalex.org/W1495576644","https://openalex.org/W2003227439","https://openalex.org/W2011626958","https://openalex.org/W2028518212","https://openalex.org/W2030844138","https://openalex.org/W2037524921","https://openalex.org/W2040777459","https://openalex.org/W2078055769","https://openalex.org/W2089176754","https://openalex.org/W2124969212","https://openalex.org/W2139250164","https://openalex.org/W2144882745","https://openalex.org/W2156075763","https://openalex.org/W2157886350","https://openalex.org/W2165744111","https://openalex.org/W2214074259","https://openalex.org/W2313610473","https://openalex.org/W2474614962","https://openalex.org/W2522854796","https://openalex.org/W2782696110","https://openalex.org/W2791079032","https://openalex.org/W2895775323","https://openalex.org/W2911228036","https://openalex.org/W2943244514","https://openalex.org/W2958952516","https://openalex.org/W2978699383","https://openalex.org/W3000922508","https://openalex.org/W3001801234","https://openalex.org/W3003228485","https://openalex.org/W3011184158","https://openalex.org/W3013758148","https://openalex.org/W3035959087","https://openalex.org/W3042229738","https://openalex.org/W3049524213","https://openalex.org/W3111997123","https://openalex.org/W3128581704","https://openalex.org/W3182124707","https://openalex.org/W3211402536","https://openalex.org/W4283015296","https://openalex.org/W4321370123","https://openalex.org/W4378212544","https://openalex.org/W4378781401","https://openalex.org/W4386609770","https://openalex.org/W4387252323","https://openalex.org/W4388233540","https://openalex.org/W7131263224"],"related_works":[],"abstract_inverted_index":{"Abstract":[0],"Viral":[1],"latency":[2,92],"reversal":[3,93],"was":[4,94,124,169],"observed":[5,171],"in":[6,38,97,102,121,126,172],"simian":[7],"immunodeficiency":[8,180],"virus":[9,40,181,194],"(SIV)-infected":[10],"rhesus":[11,52],"macaques":[12,68,104,143],"receiving":[13],"antiretroviral":[14],"therapy":[15],"(ART),":[16],"CD8\u03b1":[17],"lymphocyte":[18],"depletion":[19],"and":[20,34,129,131,155,159,203],"N-803":[21,88],"immunotherapy.":[22],"However,":[23,111],"this":[24,45],"therapeutic":[25],"approach":[26],"did":[27],"not":[28],"reduce":[29],"the":[30,62],"viral":[31,115,213],"reservoir":[32],"size":[33],"treatment":[35,109],"interruption":[36,202],"resulted":[37],"rapid":[39],"rebound.":[41],"Here,":[42],"to":[43,198,210],"address":[44],"shortfall,":[46],"we":[47],"used":[48],"four":[49],"anti-SIV":[50],"Env-specific":[51],"IgG1":[53],"monoclonal":[54],"antibodies":[55],"(RhmAbs)":[56],"that":[57,192],"recognize":[58],"unique":[59],"targets":[60],"on":[61],"SIV":[63,65,136,151],"envelope.":[64],"mac239":[66],"-infected":[67],"were":[69],"treated":[70],"with":[71,105,113,144,177,187],"ART":[72,76,82,154,201],"only":[73,95],"(group":[74,79,89],"1);":[75],"+":[77,83,85,87,139,174],"RhmAbs":[78,84],"2);":[80],"or":[81],"CD8\u03b1-depletion":[86],"3).":[90],"Robust":[91],"achieved":[96],"group":[98],"3.":[99],"Viraemia":[100],"rebounded":[101],"all":[103],"similar":[106],"kinetics":[107],"after":[108],"interruption.":[110],"compared":[112],"pre-ART":[114],"loads,":[116],"a":[117,205],"greater":[118],"fold":[119],"reduction":[120],"rebound":[122],"viraemia":[123],"seen":[125],"groups":[127],"2":[128],"3":[130],"post-treatment":[132],"control":[133],"(PTC)":[134],"required":[135],"RhmAbs.":[137],"CD4":[138,173],"T":[140,175],"cells":[141,176],"from":[142,184],"PTC":[145,199],"maintained":[146],"low":[147],"levels":[148],"of":[149],"intact":[150],"proviruses":[152],"off":[153],"expressed":[156],"increased":[157],"interferon":[158],"decreased":[160],"TGF-\u03b2":[161],"signalling":[162],"genes.":[163],"This":[164],"antiviral":[165],"gene":[166],"expression":[167],"profile":[168],"also":[170],"lower":[178],"human":[179],"(HIV)-DNA":[182],"content":[183],"ART-treated":[185],"people":[186],"HIV.":[188],"These":[189],"results":[190],"suggest":[191],"reduced":[193],"production":[195],"may":[196],"contribute":[197],"following":[200],"provide":[204],"target":[206],"for":[207],"immune-based":[208],"strategies":[209],"achieve":[211],"durable":[212],"control.":[214]},"counts_by_year":[],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2026-11-11T00:00:00"}