{"id":"https://openalex.org/W7225734061","doi":"https://doi.org/10.3390/medsci14070767","title":"Discordance Between TG/HDL Ratio and Waist-to-Height Ratio Phenotypes in Young Adults: A Cross-Sectional Study","display_name":"Discordance Between TG/HDL Ratio and Waist-to-Height Ratio Phenotypes in Young Adults: A Cross-Sectional Study","publication_year":2026,"publication_date":"2026-11-10","ids":{"openalex":"https://openalex.org/W7225734061","doi":"https://doi.org/10.3390/medsci14070767"},"language":"en","primary_location":{"id":"doi:10.3390/medsci14070767","doi":"https://doi.org/10.3390/medsci14070767","is_oa":true,"landing_page_url":"https://doi.org/10.3390/medsci14070767","pdf_url":null,"source":{"id":"https://openalex.org/S2739445098","display_name":"Medical Sciences","issn_l":"2076-3271","issn":["2076-3271"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","norway-1"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/medsci14070767","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112216729","display_name":"Autumn B. Gallegos","orcid":"https://orcid.org/0009-0005-2901-2595","observed_orcids":["https://orcid.org/0009-0005-2901-2595"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alberto Ram\u00edrez Gallegos","raw_affiliation_strings":["Balearic Islands Health Service, 07010 Palma, Spain"],"raw_orcid":"https://orcid.org/0009-0005-2901-2595","affiliations":[{"raw_affiliation_string":"Balearic Islands Health Service, 07010 Palma, Spain","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086730204","display_name":"Pedro Juan T\u00e1rraga L\u00f3pez","orcid":"https://orcid.org/0000-0002-5222-5784","observed_orcids":["https://orcid.org/0000-0002-5222-5784"]},"institutions":[{"id":"https://openalex.org/I79189158","display_name":"University of Castilla-La Mancha","ror":"https://ror.org/05r78ng12","country_code":"ES","type":"education","lineage":["https://openalex.org/I79189158"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Pedro Juan T\u00e1rraga-L\u00f3pez","raw_affiliation_strings":["Faculty of Medicine, University of Castilla La Mancha (UCLM), 02008 Albacete, Spain"],"raw_orcid":"https://orcid.org/0000-0002-5222-5784","affiliations":[{"raw_affiliation_string":"Faculty of Medicine, University of Castilla La Mancha (UCLM), 02008 Albacete, Spain","institution_ids":["https://openalex.org/I79189158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074357495","display_name":"M\u00f3nica Pi\u00f1a-D\u2019Abreu","orcid":"https://orcid.org/0000-0001-5450-8481","observed_orcids":["https://orcid.org/0000-0001-5450-8481"]},"institutions":[{"id":"https://openalex.org/I50441567","display_name":"Universitat de les Illes Balears","ror":"https://ror.org/03e10x626","country_code":"ES","type":"education","lineage":["https://openalex.org/I50441567"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"M\u00f3nica Silu Pi\u00f1a Dabreu","raw_affiliation_strings":["ADEMA-University School, University of the Balearic Islands, 07009 Palma, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ADEMA-University School, University of the Balearic Islands, 07009 Palma, Spain","institution_ids":["https://openalex.org/I50441567"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5128151445","display_name":"Lluis Rodas Ca\u00f1ellas","orcid":"https://orcid.org/0009-0006-3848-687X","observed_orcids":["https://orcid.org/0009-0006-3848-687X"]},"institutions":[{"id":"https://openalex.org/I50441567","display_name":"Universitat de les Illes Balears","ror":"https://ror.org/03e10x626","country_code":"ES","type":"education","lineage":["https://openalex.org/I50441567"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Lluis Rodas Ca\u00f1ellas","raw_affiliation_strings":["ADEMA-University School, University of the Balearic Islands, 07009 Palma, Spain"],"raw_orcid":"https://orcid.org/0009-0006-3848-687X","affiliations":[{"raw_affiliation_string":"ADEMA-University School, University of the Balearic Islands, 07009 Palma, Spain","institution_ids":["https://openalex.org/I50441567"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073357881","display_name":"\u00c1ngel Arturo L\u00f3pez\u2010Gonz\u00e1lez","orcid":"https://orcid.org/0000-0002-7439-8117","observed_orcids":["https://orcid.org/0000-0002-7439-8117"]},"institutions":[{"id":"https://openalex.org/I50441567","display_name":"Universitat de les Illes Balears","ror":"https://ror.org/03e10x626","country_code":"ES","type":"education","lineage":["https://openalex.org/I50441567"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"\u00c1ngel Arturo L\u00f3pez-Gonz\u00e1lez","raw_affiliation_strings":["ADEMA-University School, University of the Balearic Islands, 07009 Palma, Spain"],"raw_orcid":"https://orcid.org/0000-0002-7439-8117","affiliations":[{"raw_affiliation_string":"ADEMA-University School, University of the Balearic Islands, 07009 Palma, Spain","institution_ids":["https://openalex.org/I50441567"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024898763","display_name":"Jos\u00e9 Ignacio Ram\u00edrez\u2010Manent","orcid":"https://orcid.org/0000-0001-6887-4562","observed_orcids":["https://orcid.org/0000-0001-6887-4562"]},"institutions":[{"id":"https://openalex.org/I50441567","display_name":"Universitat de les Illes Balears","ror":"https://ror.org/03e10x626","country_code":"ES","type":"education","lineage":["https://openalex.org/I50441567"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Jos\u00e9 Ignacio Ram\u00edrez-Manent","raw_affiliation_strings":["ADEMA-University School, University of the Balearic Islands, 07009 Palma, Spain","Balearic Islands Health Service, 07010 Palma, Spain"],"raw_orcid":"https://orcid.org/0000-0001-6887-4562","affiliations":[{"raw_affiliation_string":"ADEMA-University School, University of the Balearic Islands, 07009 Palma, Spain","institution_ids":["https://openalex.org/I50441567"]},{"raw_affiliation_string":"Balearic Islands Health Service, 07010 Palma, Spain","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5073357881"],"corresponding_institution_ids":["https://openalex.org/I50441567"],"apc_list":{"value":1400,"currency":"CHF","value_usd":1689},"apc_paid":{"value":1400,"currency":"CHF","value_usd":1689},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"14","issue":"7","first_page":"767","last_page":"767"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12279","display_name":"Body Composition Measurement Techniques","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9093000292778015},{"id":"https://openalex.org/C61427482","wikidata":"https://www.wikidata.org/wiki/Q6656244","display_name":"Anthropometry","level":2,"score":0.6945000290870667},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.6061999797821045},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6044999957084656},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.6010000109672546},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.5544999837875366},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.44670000672340393},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.43799999356269836},{"id":"https://openalex.org/C3018380654","wikidata":"https://www.wikidata.org/wiki/Q5572348","display_name":"Fasting glucose","level":4,"score":0.4072999954223633},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.37869998812675476},{"id":"https://openalex.org/C2780578515","wikidata":"https://www.wikidata.org/wiki/Q657193","display_name":"Metabolic syndrome","level":3,"score":0.3776000142097473},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.34529998898506165},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.34130001068115234},{"id":"https://openalex.org/C205545832","wikidata":"https://www.wikidata.org/wiki/Q17156455","display_name":"Young adult","level":2,"score":0.30649998784065247},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.2897999882698059},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.2849999964237213},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.28279998898506165},{"id":"https://openalex.org/C41826966","wikidata":"https://www.wikidata.org/wiki/Q2540769","display_name":"Waist-to-height ratio","level":4,"score":0.28049999475479126},{"id":"https://openalex.org/C146304588","wikidata":"https://www.wikidata.org/wiki/Q961652","display_name":"Case-control study","level":2,"score":0.27379998564720154},{"id":"https://openalex.org/C48921125","wikidata":"https://www.wikidata.org/wiki/Q10861030","display_name":"Linear regression","level":2,"score":0.273499995470047},{"id":"https://openalex.org/C152877465","wikidata":"https://www.wikidata.org/wiki/Q208042","display_name":"Regression analysis","level":2,"score":0.26969999074935913},{"id":"https://openalex.org/C2780221984","wikidata":"https://www.wikidata.org/wiki/Q131191","display_name":"Body mass index","level":2,"score":0.2662999927997589}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.3390/medsci14070767","doi":"https://doi.org/10.3390/medsci14070767","is_oa":true,"landing_page_url":"https://doi.org/10.3390/medsci14070767","pdf_url":null,"source":{"id":"https://openalex.org/S2739445098","display_name":"Medical Sciences","issn_l":"2076-3271","issn":["2076-3271"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","norway-1"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Sciences","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.3390/medsci14070767","doi":"https://doi.org/10.3390/medsci14070767","is_oa":true,"landing_page_url":"https://doi.org/10.3390/medsci14070767","pdf_url":null,"source":{"id":"https://openalex.org/S2739445098","display_name":"Medical Sciences","issn_l":"2076-3271","issn":["2076-3271"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","norway-1"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Sciences","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W1989400130","https://openalex.org/W2030795765","https://openalex.org/W2299929805","https://openalex.org/W2599076725","https://openalex.org/W2736294384","https://openalex.org/W2741982109","https://openalex.org/W2793368865","https://openalex.org/W2886865853","https://openalex.org/W2961683851","https://openalex.org/W3035157797","https://openalex.org/W4284890877","https://openalex.org/W4313224734","https://openalex.org/W4322774851","https://openalex.org/W4380894129","https://openalex.org/W4382793856","https://openalex.org/W4387330496","https://openalex.org/W4392096845","https://openalex.org/W4393535636","https://openalex.org/W4399043324","https://openalex.org/W4400485749","https://openalex.org/W4402066166","https://openalex.org/W4402356632","https://openalex.org/W4402385080","https://openalex.org/W4404622526","https://openalex.org/W4407243165","https://openalex.org/W4407421667","https://openalex.org/W4411042746","https://openalex.org/W4414195829"],"related_works":[],"abstract_inverted_index":{"Background:":[0],"Surrogate":[1],"indices":[2,78],"proposed":[3],"to":[4],"reflect":[5],"insulin":[6,227],"resistance-related":[7],"metabolic":[8],"characteristics,":[9,22],"together":[10],"with":[11,20,50,85,145,162,189,205],"anthropometric":[12],"markers":[13],"of":[14,130,143,198],"central":[15,137],"adiposity,":[16],"have":[17],"been":[18],"associated":[19,161,178],"cardiometabolic":[21,52],"although":[23],"their":[24,47],"distributions":[25],"may":[26],"differ":[27],"in":[28,141],"young":[29],"adults.":[30],"Objective:":[31],"To":[32],"describe":[33],"the":[34,149,206],"overlap":[35],"and":[36,41,45,73,82,88,100,119,128,155,192,213],"discordance":[37],"between":[38],"TG/HDL":[39,70,103,134,172,208,211],"ratio":[40,43,212],"waist-to-height":[42],"(WtHR)":[44],"examine":[46],"cross-sectional":[48,56,218],"associations":[49],"selected":[51,207],"variables.":[53],"Methods:":[54],"A":[55],"study":[57],"included":[58,79],"12,874":[59],"adults":[60],"aged":[61],"22\u201330":[62],"years.":[63],"Four":[64],"phenotypic":[65],"groups":[66,123],"were":[67,92,105],"defined":[68],"using":[69,94],">":[71,173],"2":[72,174],"WtHR":[74,122,157,214],"\u2265":[75,158],"0.5.":[76],"Additional":[77,187],"TyG,":[80],"METS-IR,":[81],"SPISE.":[83],"Associations":[84],"fasting":[86,164,190],"glucose":[87,165,191],"elevated":[89,113,120,163],"blood":[90,193],"pressure":[91,194],"examined":[93],"logistic":[95],"regression":[96],"adjusted":[97],"for":[98],"age":[99],"sex.":[101],"Alternative":[102],"thresholds":[104],"assessed":[106],"descriptively.":[107],"Results:":[108],"The":[109],"low":[110,116],"TG/HDL/low":[111,114],"WtHR,":[112,115,118,153],"TG/HDL/high":[117,121],"comprised":[124],"81.7%,":[125],"6.8%,":[126],"8.3%,":[127],"3.2%":[129],"participants,":[131],"respectively.":[132],"Elevated":[133],"without":[135],"increased":[136],"adiposity":[138],"was":[139,160,175],"observed":[140],"5.8%":[142],"participants":[144],"normal":[146],"BMI.":[147],"In":[148],"model":[150],"including":[151],"TG/HDL,":[152],"age,":[154],"sex,":[156],"0.5":[159],"(aOR":[166,179],"2.68;":[167],"95%":[168,181],"CI":[169,182],"2.14\u20133.34),":[170],"whereas":[171],"not":[176,223],"significantly":[177],"0.87;":[180],"0.64\u20131.17;":[183],"p":[184],"=":[185],"0.343).":[186],"comparisons":[188],"showed":[195],"differing":[196],"patterns":[197],"association":[199],"across":[200],"phenotypes.":[201,219],"Phenotype":[202],"frequencies":[203],"varied":[204],"threshold.":[209],"Conclusions:":[210],"identified":[215],"partially":[216],"discordant":[217],"These":[220],"findings":[221],"do":[222],"establish":[224],"clinically":[225],"confirmed":[226],"resistance,":[228],"independent":[229],"diagnostic":[230],"validity,":[231],"causal":[232],"effects,":[233],"or":[234],"temporal":[235],"relationships.":[236]},"counts_by_year":[],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2026-11-11T00:00:00"}