{"id":"https://openalex.org/W7225729496","doi":"https://doi.org/10.3390/antiox15111457","title":"Biomarkers of Premature Biological Aging in Hodgkin Lymphoma Survivors: Advanced Glycation End Products, Oxidative Stress, Inflammation and Cellular Senescence","display_name":"Biomarkers of Premature Biological Aging in Hodgkin Lymphoma Survivors: Advanced Glycation End Products, Oxidative Stress, Inflammation and Cellular Senescence","publication_year":2026,"publication_date":"2026-11-10","ids":{"openalex":"https://openalex.org/W7225729496","doi":"https://doi.org/10.3390/antiox15111457"},"language":"en","primary_location":{"id":"doi:10.3390/antiox15111457","doi":"https://doi.org/10.3390/antiox15111457","is_oa":true,"landing_page_url":"https://doi.org/10.3390/antiox15111457","pdf_url":null,"source":{"id":"https://openalex.org/S2737566431","display_name":"Antioxidants","issn_l":"2076-3921","issn":["2076-3921"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antioxidants","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/antiox15111457","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040604270","display_name":"Eleonora Aimaretti","orcid":"https://orcid.org/0000-0001-6336-1442","observed_orcids":["https://orcid.org/0000-0001-6336-1442"]},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Eleonora Aimaretti","raw_affiliation_strings":["Department of Clinical and Biological Sciences, University of Turin, Corso Raffaello 30, 10125 Turin, Italy"],"raw_orcid":"https://orcid.org/0000-0001-6336-1442","affiliations":[{"raw_affiliation_string":"Department of Clinical and Biological Sciences, University of Turin, Corso Raffaello 30, 10125 Turin, Italy","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018914689","display_name":"Chiara Rubeo","orcid":"https://orcid.org/0000-0001-8588-851X","observed_orcids":["https://orcid.org/0000-0001-8588-851X"]},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Chiara Rubeo","raw_affiliation_strings":["Department of Clinical and Biological Sciences, University of Turin, Corso Raffaello 30, 10125 Turin, Italy"],"raw_orcid":"https://orcid.org/0000-0001-8588-851X","affiliations":[{"raw_affiliation_string":"Department of Clinical and Biological Sciences, University of Turin, Corso Raffaello 30, 10125 Turin, Italy","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072297631","display_name":"Mario Levis","orcid":"https://orcid.org/0000-0002-7668-3296","observed_orcids":["https://orcid.org/0000-0002-7668-3296"]},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Mario Levis","raw_affiliation_strings":["Department of Oncology, University of Turin, Via Genova 3, 10126 Torino, Italy"],"raw_orcid":"https://orcid.org/0000-0002-7668-3296","affiliations":[{"raw_affiliation_string":"Department of Oncology, University of Turin, Via Genova 3, 10126 Torino, Italy","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070003191","display_name":"Barbara Botto","orcid":"https://orcid.org/0009-0005-7514-6172","observed_orcids":["https://orcid.org/0009-0005-7514-6172"]},"institutions":[{"id":"https://openalex.org/I4210086903","display_name":"Azienda Ospedaliera Citta' della Salute e della Scienza di Torino","ror":"https://ror.org/001f7a930","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210086903"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Barbara Botto","raw_affiliation_strings":["Division of Hematology and Allogeneic Stem Cell Transplant Unit, A.O.U. Citt\u00e0 della Salute e della Scienza di Torino, C.so Bramante 88, 10126 Turin, Italy"],"raw_orcid":"https://orcid.org/0009-0005-7514-6172","affiliations":[{"raw_affiliation_string":"Division of Hematology and Allogeneic Stem Cell Transplant Unit, A.O.U. Citt\u00e0 della Salute e della Scienza di Torino, C.so Bramante 88, 10126 Turin, Italy","institution_ids":["https://openalex.org/I4210086903"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001532055","display_name":"Federica Cavallo","orcid":"https://orcid.org/0000-0003-4571-1060","observed_orcids":["https://orcid.org/0000-0003-4571-1060","https://orcid.org/0000-0003-2047-1099"]},"institutions":[{"id":"https://openalex.org/I4210086903","display_name":"Azienda Ospedaliera Citta' della Salute e della Scienza di Torino","ror":"https://ror.org/001f7a930","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210086903"]},{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Federica Cavallo","raw_affiliation_strings":["Division of Hematology, Department of Molecular Biotechnology and Health Sciences, University of Torino, A.O.U Citt\u00e0 della Salute e della Scienza di Torino, C.so Bramante 88/90, 10126 Turin, Italy"],"raw_orcid":"https://orcid.org/0000-0003-2047-1099","affiliations":[{"raw_affiliation_string":"Division of Hematology, Department of Molecular Biotechnology and Health Sciences, University of Torino, A.O.U Citt\u00e0 della Salute e della Scienza di Torino, C.so Bramante 88/90, 10126 Turin, Italy","institution_ids":["https://openalex.org/I4210086903","https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114215212","display_name":"Michela Presti","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210086903","display_name":"Azienda Ospedaliera Citta' della Salute e della Scienza di Torino","ror":"https://ror.org/001f7a930","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210086903"]},{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Michela Presti","raw_affiliation_strings":["Department of Medical Sciences, University of Turin, via Genova, 3, 10126 Torino, Italy","Division of Oncological Endocrinology, A.O.U Citt\u00e0 della Salute e della Scienza di Torino, 10126 Turin, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Sciences, University of Turin, via Genova, 3, 10126 Torino, Italy","institution_ids":["https://openalex.org/I55143463"]},{"raw_affiliation_string":"Division of Oncological Endocrinology, A.O.U Citt\u00e0 della Salute e della Scienza di Torino, 10126 Turin, Italy","institution_ids":["https://openalex.org/I4210086903"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114883900","display_name":"Elisa Pettineo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Elisa Pettineo","raw_affiliation_strings":["Department of Clinical and Biological Sciences, University of Turin, Corso Raffaello 30, 10125 Turin, Italy"],"raw_orcid":"https://orcid.org/0009-0006-0758-7328","affiliations":[{"raw_affiliation_string":"Department of Clinical and Biological Sciences, University of Turin, Corso Raffaello 30, 10125 Turin, Italy","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011220231","display_name":"Gustavo Ferreira Alves","orcid":"https://orcid.org/0000-0003-2529-2006","observed_orcids":["https://orcid.org/0000-0003-2529-2006"]},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Gustavo Ferreira Alves","raw_affiliation_strings":["Department of Neurosciences \u201cRita Levi Montalcini\u201d, University of Turin, Corso Raffaello 30, 10125 Turin, Italy"],"raw_orcid":"https://orcid.org/0000-0003-2529-2006","affiliations":[{"raw_affiliation_string":"Department of Neurosciences \u201cRita Levi Montalcini\u201d, University of Turin, Corso Raffaello 30, 10125 Turin, Italy","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041658752","display_name":"Federica Dal Bello","orcid":"https://orcid.org/0000-0003-0726-3025","observed_orcids":["https://orcid.org/0000-0003-0726-3025"]},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Federica Dal Bello","raw_affiliation_strings":["Department of Molecular Biotechnology and Health Science, University of Turin, Via Nizza 52, 10126 Turin, Italy"],"raw_orcid":"https://orcid.org/0000-0003-0726-3025","affiliations":[{"raw_affiliation_string":"Department of Molecular Biotechnology and Health Science, University of Turin, Via Nizza 52, 10126 Turin, Italy","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081309794","display_name":"Alessandro Godono","orcid":"https://orcid.org/0000-0001-8095-5461","observed_orcids":["https://orcid.org/0000-0001-8095-5461"]},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alessandro Godono","raw_affiliation_strings":["Department of Public Health and Paediatric Sciences, University of Turin, Via Zuretti 29, 10126 Turin, Italy"],"raw_orcid":"https://orcid.org/0000-0001-8095-5461","affiliations":[{"raw_affiliation_string":"Department of Public Health and Paediatric Sciences, University of Turin, Via Zuretti 29, 10126 Turin, Italy","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016751546","display_name":"Roberto Freilone","orcid":"https://orcid.org/0000-0002-6003-3328","observed_orcids":["https://orcid.org/0000-0002-6003-3328"]},"institutions":[{"id":"https://openalex.org/I4210086903","display_name":"Azienda Ospedaliera Citta' della Salute e della Scienza di Torino","ror":"https://ror.org/001f7a930","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210086903"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Roberto Freilone","raw_affiliation_strings":["Division of Hematology and Allogeneic Stem Cell Transplant Unit, A.O.U. Citt\u00e0 della Salute e della Scienza di Torino, C.so Bramante 88, 10126 Turin, Italy"],"raw_orcid":"https://orcid.org/0000-0002-6003-3328","affiliations":[{"raw_affiliation_string":"Division of Hematology and Allogeneic Stem Cell Transplant Unit, A.O.U. Citt\u00e0 della Salute e della Scienza di Torino, C.so Bramante 88, 10126 Turin, Italy","institution_ids":["https://openalex.org/I4210086903"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038143009","display_name":"Benedetto Bruno","orcid":"https://orcid.org/0000-0002-7299-6770","observed_orcids":["https://orcid.org/0000-0002-7299-6770"]},"institutions":[{"id":"https://openalex.org/I4210086903","display_name":"Azienda Ospedaliera Citta' della Salute e della Scienza di Torino","ror":"https://ror.org/001f7a930","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210086903"]},{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Benedetto Bruno","raw_affiliation_strings":["Division of Hematology, Department of Molecular Biotechnology and Health Sciences, University of Torino, A.O.U Citt\u00e0 della Salute e della Scienza di Torino, C.so Bramante 88/90, 10126 Turin, Italy"],"raw_orcid":"https://orcid.org/0000-0002-7299-6770","affiliations":[{"raw_affiliation_string":"Division of Hematology, Department of Molecular Biotechnology and Health Sciences, University of Torino, A.O.U Citt\u00e0 della Salute e della Scienza di Torino, C.so Bramante 88/90, 10126 Turin, Italy","institution_ids":["https://openalex.org/I4210086903","https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112053008","display_name":"Umberto Ricardi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Umberto Ricardi","raw_affiliation_strings":["Department of Oncology, University of Turin, Via Genova 3, 10126 Torino, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, University of Turin, Via Genova 3, 10126 Torino, Italy","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000989087","display_name":"Emanuela Arvat","orcid":"https://orcid.org/0000-0001-5689-4400","observed_orcids":["https://orcid.org/0000-0001-5689-4400"]},"institutions":[{"id":"https://openalex.org/I4210086903","display_name":"Azienda Ospedaliera Citta' della Salute e della Scienza di Torino","ror":"https://ror.org/001f7a930","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210086903"]},{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Emanuela Arvat","raw_affiliation_strings":["Department of Medical Sciences, University of Turin, via Genova, 3, 10126 Torino, Italy","Division of Oncological Endocrinology, A.O.U Citt\u00e0 della Salute e della Scienza di Torino, 10126 Turin, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Sciences, University of Turin, via Genova, 3, 10126 Torino, Italy","institution_ids":["https://openalex.org/I55143463"]},{"raw_affiliation_string":"Division of Oncological Endocrinology, A.O.U Citt\u00e0 della Salute e della Scienza di Torino, 10126 Turin, Italy","institution_ids":["https://openalex.org/I4210086903"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043387826","display_name":"Stefania Pizzimenti","orcid":"https://orcid.org/0000-0001-6937-8632","observed_orcids":["https://orcid.org/0000-0001-6937-8632"]},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Stefania Pizzimenti","raw_affiliation_strings":["Department of Clinical and Biological Sciences, University of Turin, Corso Raffaello 30, 10125 Turin, Italy"],"raw_orcid":"https://orcid.org/0000-0001-6937-8632","affiliations":[{"raw_affiliation_string":"Department of Clinical and Biological Sciences, University of Turin, Corso Raffaello 30, 10125 Turin, Italy","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014865083","display_name":"Manuela Aragno","orcid":"https://orcid.org/0000-0002-0453-5235","observed_orcids":["https://orcid.org/0000-0002-0453-5235"]},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Manuela Aragno","raw_affiliation_strings":["Department of Clinical and Biological Sciences, University of Turin, Corso Raffaello 30, 10125 Turin, Italy"],"raw_orcid":"https://orcid.org/0000-0002-0453-5235","affiliations":[{"raw_affiliation_string":"Department of Clinical and Biological Sciences, University of Turin, Corso Raffaello 30, 10125 Turin, Italy","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077841299","display_name":"Massimo Collino","orcid":"https://orcid.org/0000-0001-8782-3496","observed_orcids":["https://orcid.org/0000-0001-8782-3496"]},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Massimo Collino","raw_affiliation_strings":["Department of Neurosciences \u201cRita Levi Montalcini\u201d, University of Turin, Corso Raffaello 30, 10125 Turin, Italy"],"raw_orcid":"https://orcid.org/0000-0001-8782-3496","affiliations":[{"raw_affiliation_string":"Department of Neurosciences \u201cRita Levi Montalcini\u201d, University of Turin, Corso Raffaello 30, 10125 Turin, Italy","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076643968","display_name":"Francesco Felicetti","orcid":"https://orcid.org/0000-0002-6642-8750","observed_orcids":["https://orcid.org/0000-0002-6642-8750"]},"institutions":[{"id":"https://openalex.org/I4210086903","display_name":"Azienda Ospedaliera Citta' della Salute e della Scienza di Torino","ror":"https://ror.org/001f7a930","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210086903"]},{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Francesco Carlo Felicetti","raw_affiliation_strings":["Department of Medical Sciences, University of Turin, via Genova, 3, 10126 Torino, Italy","Division of Oncological Endocrinology, A.O.U Citt\u00e0 della Salute e della Scienza di Torino, 10126 Turin, Italy"],"raw_orcid":"https://orcid.org/0000-0002-6642-8750","affiliations":[{"raw_affiliation_string":"Department of Medical Sciences, University of Turin, via Genova, 3, 10126 Torino, Italy","institution_ids":["https://openalex.org/I55143463"]},{"raw_affiliation_string":"Division of Oncological Endocrinology, A.O.U Citt\u00e0 della Salute e della Scienza di Torino, 10126 Turin, Italy","institution_ids":["https://openalex.org/I4210086903"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5043387826","https://openalex.org/A5076643968"],"corresponding_institution_ids":["https://openalex.org/I4210086903","https://openalex.org/I55143463"],"apc_list":{"value":2900,"currency":"CHF","value_usd":3499},"apc_paid":{"value":2900,"currency":"CHF","value_usd":3499},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"15","issue":"11","first_page":"1457","last_page":"1457"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11142","display_name":"Advanced Glycation End Products research","score":0.9628999829292297,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11142","display_name":"Advanced Glycation End Products research","score":0.9628999829292297,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11141","display_name":"Childhood Cancer Survivors' Quality of Life","score":0.011900000274181366,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10937","display_name":"Telomeres, Telomerase, and Senescence","score":0.00570000009611249,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[],"concepts":[{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.829800009727478},{"id":"https://openalex.org/C147990577","wikidata":"https://www.wikidata.org/wiki/Q25790","display_name":"Glycation","level":3,"score":0.8037999868392944},{"id":"https://openalex.org/C2778857457","wikidata":"https://www.wikidata.org/wiki/Q153641","display_name":"Rage (emotion)","level":2,"score":0.6754000186920166},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.6553999781608582},{"id":"https://openalex.org/C2909947164","wikidata":"https://www.wikidata.org/wiki/Q6139748","display_name":"Premature aging","level":2,"score":0.6466000080108643},{"id":"https://openalex.org/C203522944","wikidata":"https://www.wikidata.org/wiki/Q288322","display_name":"Autophagy","level":3,"score":0.5547000169754028},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5529000163078308},{"id":"https://openalex.org/C522857546","wikidata":"https://www.wikidata.org/wiki/Q2070979","display_name":"Senescence","level":2,"score":0.5317999720573425},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.47200000286102295},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4383000135421753},{"id":"https://openalex.org/C2776997535","wikidata":"https://www.wikidata.org/wiki/Q2556837","display_name":"Advanced glycation end-product","level":4,"score":0.4350999891757965},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4311999976634979},{"id":"https://openalex.org/C57600042","wikidata":"https://www.wikidata.org/wiki/Q227564","display_name":"Oxidative phosphorylation","level":2,"score":0.41040000319480896},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.40880000591278076},{"id":"https://openalex.org/C2992779791","wikidata":"https://www.wikidata.org/wiki/Q209369","display_name":"Hodgkin lymphoma","level":3,"score":0.3903000056743622},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.3792000114917755},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.37630000710487366},{"id":"https://openalex.org/C2775997469","wikidata":"https://www.wikidata.org/wiki/Q18029196","display_name":"MMP9","level":4,"score":0.35899999737739563},{"id":"https://openalex.org/C2779338263","wikidata":"https://www.wikidata.org/wiki/Q208414","display_name":"Lymphoma","level":2,"score":0.35339999198913574},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.3393000066280365},{"id":"https://openalex.org/C2780545709","wikidata":"https://www.wikidata.org/wiki/Q21130552","display_name":"HMGB1","level":3,"score":0.33500000834465027},{"id":"https://openalex.org/C55728118","wikidata":"https://www.wikidata.org/wiki/Q425402","display_name":"Metalloproteinase","level":3,"score":0.31869998574256897},{"id":"https://openalex.org/C500499127","wikidata":"https://www.wikidata.org/wiki/Q332154","display_name":"Ageing","level":2,"score":0.31049999594688416},{"id":"https://openalex.org/C2776252253","wikidata":"https://www.wikidata.org/wiki/Q7663815","display_name":"Systemic inflammation","level":3,"score":0.2777999937534332},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2766000032424927},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.2540000081062317}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.3390/antiox15111457","doi":"https://doi.org/10.3390/antiox15111457","is_oa":true,"landing_page_url":"https://doi.org/10.3390/antiox15111457","pdf_url":null,"source":{"id":"https://openalex.org/S2737566431","display_name":"Antioxidants","issn_l":"2076-3921","issn":["2076-3921"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antioxidants","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.3390/antiox15111457","doi":"https://doi.org/10.3390/antiox15111457","is_oa":true,"landing_page_url":"https://doi.org/10.3390/antiox15111457","pdf_url":null,"source":{"id":"https://openalex.org/S2737566431","display_name":"Antioxidants","issn_l":"2076-3921","issn":["2076-3921"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antioxidants","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":46,"referenced_works":["https://openalex.org/W1973255904","https://openalex.org/W1988228415","https://openalex.org/W2015758016","https://openalex.org/W2029275609","https://openalex.org/W2038998835","https://openalex.org/W2102761280","https://openalex.org/W2107277218","https://openalex.org/W2126005596","https://openalex.org/W2126729859","https://openalex.org/W2136497849","https://openalex.org/W2138402374","https://openalex.org/W2165194767","https://openalex.org/W2296184960","https://openalex.org/W2342734591","https://openalex.org/W2409710963","https://openalex.org/W2561396377","https://openalex.org/W2732089561","https://openalex.org/W2752414510","https://openalex.org/W2768762801","https://openalex.org/W2885738092","https://openalex.org/W2912422018","https://openalex.org/W2983106163","https://openalex.org/W2995333915","https://openalex.org/W3024177706","https://openalex.org/W3028663147","https://openalex.org/W3085341153","https://openalex.org/W3129930642","https://openalex.org/W3173719719","https://openalex.org/W3203461521","https://openalex.org/W3203834151","https://openalex.org/W3215038320","https://openalex.org/W4213157453","https://openalex.org/W4223542076","https://openalex.org/W4224221837","https://openalex.org/W4280626694","https://openalex.org/W4288693269","https://openalex.org/W4312066302","https://openalex.org/W4313522989","https://openalex.org/W4319073289","https://openalex.org/W4366602564","https://openalex.org/W4386790678","https://openalex.org/W4389166615","https://openalex.org/W4399285708","https://openalex.org/W4399609630","https://openalex.org/W4399755833","https://openalex.org/W4403381422"],"related_works":[],"abstract_inverted_index":{"Childhood,":[0],"adolescent,":[1],"and":[2,24,41,69,89,114,137,144,153,192],"young":[3],"adult":[4],"cancer":[5],"survivors":[6,78,113,124,136],"(CAYACS)":[7],"are":[8,206],"at":[9],"increased":[10],"risk":[11],"of":[12,65,81,85,93,104,129,200,213,220],"late":[13],"morbidity,":[14],"potentially":[15],"reflecting":[16],"premature":[17,172],"biological":[18,61,168,215],"aging.":[19],"Cellular":[20],"senescence,":[21,174],"oxidative":[22,120,189],"stress,":[23],"chronic":[25,193],"inflammation":[26,194],"may":[27,195],"contribute":[28],"via":[29],"interconnected":[30],"pathways,":[31,191],"including":[32],"signaling":[33,106],"mediated":[34],"by":[35],"advanced":[36],"glycation":[37],"end":[38],"products":[39],"(AGEs)":[40],"their":[42,60,86],"receptor,":[43],"RAGE.":[44],"This":[45],"study":[46],"investigated":[47],"biomarkers":[48],"related":[49],"to":[50,97,197,208],"these":[51,214],"pathways":[52],"in":[53,109,142,181,186,217],"CAYACS-treated":[54],"Hodgkin":[55],"lymphoma":[56],"(HL)":[57],"patients,":[58],"comparing":[59],"profile":[62,103,169],"with":[63,171,175],"that":[64,164],"age-matched":[66,98,132,159],"(Controls":[67,75],"1)":[68],"older":[70,182],"(aged":[71],"50\u201365)":[72],"healthy":[73,183],"controls":[74],"2).":[76],"HL":[77,112,123,135],"exhibited":[79],"accumulation":[80],"AGEs,":[82],"higher":[83,126,149,154],"expression":[84],"receptor":[87],"RAGE":[88,95],"lower":[90],"circulating":[91],"levels":[92,128,152,157],"soluble":[94],"compared":[96],"Controls":[99,110,115,138,160],"1.":[100,161],"A":[101],"similar":[102],"AGE-RAGE":[105,187],"was":[107],"observed":[108,180],"2.":[111],"2":[116,139],"showed":[117,140],"an":[118],"altered":[119],"status.":[121],"Moreover,":[122],"reported":[125],"plasma":[127,150],"IL-6":[130],"than":[131,158],"controls.":[133],"Furthermore,":[134],"alterations":[141,216],"autophagy":[143],"mitophagy.":[145],"Finally,":[146],"CAYACS":[147,165],"had":[148],"MMP9":[151],"p16":[155],"mRNA":[156],"Data":[162],"show":[163],"exhibit":[166],"a":[167],"consistent":[170],"cellular":[173],"several":[176],"features":[177],"resembling":[178],"those":[179],"individuals.":[184],"Alterations":[185],"signaling,":[188],"stress-related":[190],"lead":[196],"the":[198,210,218],"onset":[199],"this":[201],"phenotype.":[202],"Further":[203],"longitudinal":[204],"studies":[205],"needed":[207],"clarify":[209],"potential":[211],"role":[212],"development":[219],"long-term":[221],"treatment-related":[222],"complications.":[223]},"counts_by_year":[],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2026-11-11T00:00:00"}