{"id":"https://openalex.org/W7225658678","doi":"https://doi.org/10.14738/bjhr.1306.12336","title":"Molecular Detection of Selected Adhesion-Related Genes (fnbA and papC) in Proteus Species Isolated from Clinical Specimens at Federal Medical Centre, Yenagoa, Bayelsa State, Nigeria: A Preliminary Study","display_name":"Molecular Detection of Selected Adhesion-Related Genes (fnbA and papC) in Proteus Species Isolated from Clinical Specimens at Federal Medical Centre, Yenagoa, Bayelsa State, Nigeria: A Preliminary Study","publication_year":2026,"publication_date":"2026-11-09","ids":{"openalex":"https://openalex.org/W7225658678","doi":"https://doi.org/10.14738/bjhr.1306.12336"},"language":"en","primary_location":{"id":"doi:10.14738/bjhr.1306.12336","doi":"https://doi.org/10.14738/bjhr.1306.12336","is_oa":true,"landing_page_url":"https://doi.org/10.14738/bjhr.1306.12336","pdf_url":"https://scholarpublishing.org/journals/index.php/BJHR/article/download/12336/12510","source":{"id":"https://openalex.org/S4393919490","display_name":"British journal of healthcare and medical research","issn_l":"2753-7919","issn":["2753-7919"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Healthcare and Medical Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://scholarpublishing.org/journals/index.php/BJHR/article/download/12336/12510","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112895048","display_name":"Tolulope Alade","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I147765412","display_name":"Niger Delta University","ror":"https://ror.org/03pwcr767","country_code":"NG","type":"education","lineage":["https://openalex.org/I147765412"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"Tolulope Alade","raw_affiliation_strings":["Niger Delta University, Wilberforce Island, Amassoma, Bayelsa State, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Niger Delta University, Wilberforce Island, Amassoma, Bayelsa State, Nigeria","institution_ids":["https://openalex.org/I147765412"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161341671","display_name":"Ewaoche Sunday","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3132818693","display_name":"Baze University","ror":"https://ror.org/007tbc964","country_code":"NG","type":"education","lineage":["https://openalex.org/I3132818693"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"Ewaoche Sunday","raw_affiliation_strings":["Baze University, Abuja, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Baze University, Abuja, Nigeria","institution_ids":["https://openalex.org/I3132818693"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5161316874","display_name":"Gbenovie Lucky","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I147765412","display_name":"Niger Delta University","ror":"https://ror.org/03pwcr767","country_code":"NG","type":"education","lineage":["https://openalex.org/I147765412"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"Gbenovie Lucky","raw_affiliation_strings":["Niger Delta University, Wilberforce Island, Amassoma, Bayelsa State, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Niger Delta University, Wilberforce Island, Amassoma, Bayelsa State, Nigeria","institution_ids":["https://openalex.org/I147765412"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"13","issue":"06","first_page":"30","last_page":"37"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11232","display_name":"Urinary Tract Infections Management","score":0.25049999356269836,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11232","display_name":"Urinary Tract Infections Management","score":0.25049999356269836,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10943","display_name":"Escherichia coli research studies","score":0.14499999582767487,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12167","display_name":"Bacterial Identification and Susceptibility Testing","score":0.12809999287128448,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/proteus","display_name":"Proteus","score":0.9409999847412109},{"id":"https://openalex.org/keywords/fnba","display_name":"fnbA","score":0.75},{"id":"https://openalex.org/keywords/papc","display_name":"papC","score":0.9940000176429749},{"id":"https://openalex.org/keywords/urinary-tract-infection","display_name":"urinary tract infection","score":0.8410000205039978},{"id":"https://openalex.org/keywords/vaginitis","display_name":"vaginal infection","score":0.7639999985694885},{"id":"https://openalex.org/keywords/clinical-isolates","display_name":"clinical isolates","score":0.7900000214576721},{"id":"https://openalex.org/keywords/virulence-markers","display_name":"virulence markers","score":0.652999997138977},{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.7590000033378601},{"id":"https://openalex.org/keywords/nosocomial-infections","display_name":"nosocomial infections","score":0.3970000147819519},{"id":"https://openalex.org/keywords/bayelsa-state","display_name":"Bayelsa State","score":0.6970000267028809}],"concepts":[{"id":"https://openalex.org/C2779464495","wikidata":"https://www.wikidata.org/wiki/Q132229","display_name":"Proteus","level":4,"score":0.8069000244140625},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7791000008583069},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.7106000185012817},{"id":"https://openalex.org/C8185291","wikidata":"https://www.wikidata.org/wiki/Q2844457","display_name":"Amplicon","level":4,"score":0.6173999905586243},{"id":"https://openalex.org/C2780662933","wikidata":"https://www.wikidata.org/wiki/Q2701588","display_name":"Proteus vulgaris","level":4,"score":0.5260000228881836},{"id":"https://openalex.org/C2778039505","wikidata":"https://www.wikidata.org/wiki/Q311273","display_name":"Proteus mirabilis","level":4,"score":0.4593000113964081},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.44369998574256897},{"id":"https://openalex.org/C2909657710","wikidata":"https://www.wikidata.org/wiki/Q132229","display_name":"Proteus Infections","level":5,"score":0.42989999055862427},{"id":"https://openalex.org/C205501099","wikidata":"https://www.wikidata.org/wiki/Q188990","display_name":"Gram staining","level":3,"score":0.4262000024318695},{"id":"https://openalex.org/C2776870249","wikidata":"https://www.wikidata.org/wiki/Q149128","display_name":"Bacilli","level":3,"score":0.37540000677108765},{"id":"https://openalex.org/C78063203","wikidata":"https://www.wikidata.org/wiki/Q3062596","display_name":"DNA extraction","level":4,"score":0.3671000003814697},{"id":"https://openalex.org/C2778910516","wikidata":"https://www.wikidata.org/wiki/Q380136","display_name":"Enterobacteriaceae","level":4,"score":0.3569999933242798},{"id":"https://openalex.org/C2779116282","wikidata":"https://www.wikidata.org/wiki/Q131854","display_name":"Klebsiella","level":4,"score":0.35440000891685486},{"id":"https://openalex.org/C2777637488","wikidata":"https://www.wikidata.org/wiki/Q31856","display_name":"Pseudomonas aeruginosa","level":3,"score":0.35030001401901245},{"id":"https://openalex.org/C2777058267","wikidata":"https://www.wikidata.org/wiki/Q132592","display_name":"Klebsiella pneumoniae","level":4,"score":0.34200000762939453},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.3398999869823456},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.3239000141620636},{"id":"https://openalex.org/C84623179","wikidata":"https://www.wikidata.org/wiki/Q102036119","display_name":"RAPD","level":4,"score":0.32269999384880066},{"id":"https://openalex.org/C105878827","wikidata":"https://www.wikidata.org/wiki/Q2041929","display_name":"Colonisation","level":3,"score":0.3158000111579895},{"id":"https://openalex.org/C2775965595","wikidata":"https://www.wikidata.org/wiki/Q1365581","display_name":"Micrococcaceae","level":4,"score":0.30329999327659607},{"id":"https://openalex.org/C2779288629","wikidata":"https://www.wikidata.org/wiki/Q199695","display_name":"Staphylococcus","level":4,"score":0.2953000068664551},{"id":"https://openalex.org/C2778271344","wikidata":"https://www.wikidata.org/wiki/Q903395","display_name":"Agarose gel electrophoresis","level":3,"score":0.27889999747276306},{"id":"https://openalex.org/C49105822","wikidata":"https://www.wikidata.org/wiki/Q176996","display_name":"Polymerase chain reaction","level":3,"score":0.27790001034736633},{"id":"https://openalex.org/C77411442","wikidata":"https://www.wikidata.org/wiki/Q181100","display_name":"Urinary system","level":2,"score":0.2750000059604645},{"id":"https://openalex.org/C168007829","wikidata":"https://www.wikidata.org/wiki/Q857299","display_name":"Restriction fragment length polymorphism","level":4,"score":0.2727999985218048},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2556000053882599},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.2500999867916107}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.14738/bjhr.1306.12336","doi":"https://doi.org/10.14738/bjhr.1306.12336","is_oa":true,"landing_page_url":"https://doi.org/10.14738/bjhr.1306.12336","pdf_url":"https://scholarpublishing.org/journals/index.php/BJHR/article/download/12336/12510","source":{"id":"https://openalex.org/S4393919490","display_name":"British journal of healthcare and medical research","issn_l":"2753-7919","issn":["2753-7919"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Healthcare and Medical Research","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.14738/bjhr.1306.12336","doi":"https://doi.org/10.14738/bjhr.1306.12336","is_oa":true,"landing_page_url":"https://doi.org/10.14738/bjhr.1306.12336","pdf_url":"https://scholarpublishing.org/journals/index.php/BJHR/article/download/12336/12510","source":{"id":"https://openalex.org/S4393919490","display_name":"British journal of healthcare and medical research","issn_l":"2753-7919","issn":["2753-7919"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Healthcare and Medical Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225658678.pdf","grobid_xml":"https://content.openalex.org/works/W7225658678.grobid-xml"},"referenced_works_count":1,"referenced_works":["https://openalex.org/W2789184906"],"related_works":["https://openalex.org/W4399738753","https://openalex.org/W4391038279","https://openalex.org/W2623845187","https://openalex.org/W3154944685","https://openalex.org/W4386642371","https://openalex.org/W4285314395","https://openalex.org/W4211167074","https://openalex.org/W2342162879","https://openalex.org/W2339525855","https://openalex.org/W2086538363"],"abstract_inverted_index":{"Background:":[0],"Proteus":[1,39,52,113,153,174,233],"species":[2,53,225,234],"are":[3,267],"opportunistic":[4],"Gram-negative":[5],"bacilli":[6],"frequently":[7,178],"implicated":[8],"in":[9,34,37,78],"urinary":[10],"and":[11,20,30,63,75,91,109,122,127,140,170,183,226,243,265,281,297,301],"genital":[12],"tract":[13],"infections.":[14],"Adhesion-related":[15],"genes":[16,26,292],"contribute":[17],"to":[18,64],"colonisation":[19],"persistence;":[21],"however,":[22],"the":[23,49,71,185,190,203,274],"relevance":[24],"of":[25,51,73,81,86,239,272,276],"such":[27],"as":[28],"fnbA":[29,74,126,264],"papC":[31,76,266],"(classically":[32],"described":[33],"other":[35],"genera)":[36],"clinical":[38,55,88],"isolates":[40,114,154,159,192,240,277],"from":[41,179,184,241],"Nigeria":[42],"remains":[43],"poorly":[44],"documented.":[45],"Objective:":[46],"To":[47],"determine":[48],"distribution":[50,139],"among":[54,253],"specimens":[56,89],"at":[57,247],"Federal":[58],"Medical":[59],"Centre":[60],"(FMC)":[61],"Yenagoa":[62],"perform":[65],"a":[66,79],"preliminary":[67,258],"molecular":[68,259],"screen":[69],"for":[70,117,206],"presence":[72],"sequences":[77],"subset":[80],"isolates.":[82],"Methods:":[83],"A":[84],"total":[85],"196":[87],"(urine":[90],"high":[92,244],"vaginal":[93,245],"swabs)":[94],"were":[95,102,115,130,143,156,283],"processed":[96],"using":[97],"standard":[98],"bacteriological":[99],"methods.":[100],"Isolates":[101],"identified":[103],"by":[104,132,145,194],"colonial":[105],"morphology,":[106],"Gram":[107],"staining":[108],"biochemical":[110],"tests.":[111],"Eight":[112],"selected":[116],"DNA":[118],"extraction":[119],"(boiling":[120],"method)":[121],"conventional":[123],"PCR":[124],"targeting":[125],"papC.":[128,216],"Amplicons":[129],"visualised":[131],"agarose":[133],"gel":[134],"electrophoresis.":[135],"Associations":[136],"between":[137,223],"isolate":[138],"specimen":[141,227],"source":[142,228],"examined":[144],"chi-square":[146],"test":[147],"(\u03b1":[148],"=":[149,230],"0.05).":[150],"Results:":[151],"Twenty-five":[152],"(12.8%)":[155],"recovered.":[157],"Other":[158],"included":[160],"Escherichia":[161],"coli":[162],"(23.0%),":[163,166],"Staphylococcus":[164],"aureus":[165],"Pseudomonas":[167],"aeruginosa":[168],"(21.4%)":[169],"Klebsiella":[171],"pneumoniae":[172],"(19.9%).":[173],"was":[175,221,279],"recovered":[176],"more":[177],"female":[180],"patients":[181],"(64%)":[182],"21\u201330-year":[186],"age":[187],"group.":[188],"Of":[189],"eight":[191],"tested":[193,278],"PCR,":[195],"all":[196],"(100%)":[197],"yielded":[198,211],"an":[199,212,236],"amplicon":[200,213],"consistent":[201,214],"with":[202,215,250],"expected":[204],"size":[205],"fnbA,":[207],"while":[208],"four":[209],"(50%)":[210],"No":[217],"statistically":[218],"significant":[219],"association":[220],"observed":[222],"bacterial":[224],"(p":[229],"0.456).":[231],"Conclusions:":[232],"constitute":[235],"important":[237],"proportion":[238],"urine":[242],"swabs":[246],"FMC":[248],"Yenagoa,":[249],"higher":[251],"recovery":[252],"young":[254],"adult":[255],"females.":[256],"The":[257],"findings":[260],"require":[261],"cautious":[262],"interpretation:":[263],"not":[268,284],"established":[269],"virulence":[270],"markers":[271],"Proteus,":[273],"number":[275],"small,":[280],"amplicons":[282],"sequenced.":[285],"Future":[286],"work":[287],"should":[288],"target":[289],"Proteus-specific":[290],"adhesin":[291],"(e.g.,":[293],"mrpA,":[294],"ucaA,":[295],"pmfA)":[296],"include":[298],"species-level":[299],"identification":[300],"sequence":[302],"confirmation.":[303]},"counts_by_year":[],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2026-11-10T00:00:00"}