{"id":"https://openalex.org/W7225647199","doi":"https://doi.org/10.1080/14796694.2026.2760122","title":"Diagnostic performance of MRI, endorectal ultrasound, and FAPI PET/MRI for identifying pathological complete response after short-course radiotherapy and chemoimmunotherapy in locally advanced rectal cancer: a retrospective study","display_name":"Diagnostic performance of MRI, endorectal ultrasound, and FAPI PET/MRI for identifying pathological complete response after short-course radiotherapy and chemoimmunotherapy in locally advanced rectal cancer: a retrospective study","publication_year":2026,"publication_date":"2026-11-09","ids":{"openalex":"https://openalex.org/W7225647199","doi":"https://doi.org/10.1080/14796694.2026.2760122","pmid":"https://pubmed.ncbi.nlm.nih.gov/43001364"},"language":"en","primary_location":{"id":"doi:10.1080/14796694.2026.2760122","doi":"https://doi.org/10.1080/14796694.2026.2760122","is_oa":false,"landing_page_url":"https://doi.org/10.1080/14796694.2026.2760122","pdf_url":null,"source":{"id":"https://openalex.org/S174572715","display_name":"Future Oncology","issn_l":"1479-6694","issn":["1479-6694","1744-8301"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310321119","host_organization_name":"Future Medicine","host_organization_lineage":["https://openalex.org/P4310321119"],"host_organization_lineage_names":["Future Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Future Oncology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072998218","display_name":"Zhihao Hu","orcid":"https://orcid.org/0009-0005-0565-9052","observed_orcids":["https://orcid.org/0009-0005-0565-9052"]},"institutions":[{"id":"https://openalex.org/I151075929","display_name":"Army Medical University","ror":"https://ror.org/05w21nn13","country_code":"CN","type":"education","lineage":["https://openalex.org/I151075929"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhihao Hu","raw_affiliation_strings":["Army Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Army Medical University","institution_ids":["https://openalex.org/I151075929"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161305310","display_name":"Min Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I151075929","display_name":"Army Medical University","ror":"https://ror.org/05w21nn13","country_code":"CN","type":"education","lineage":["https://openalex.org/I151075929"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Min Chen","raw_affiliation_strings":["Army Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Army Medical University","institution_ids":["https://openalex.org/I151075929"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100344237","display_name":"Hua Li","orcid":"https://orcid.org/0000-0002-5204-7746","observed_orcids":["https://orcid.org/0000-0002-5204-7746"]},"institutions":[{"id":"https://openalex.org/I151075929","display_name":"Army Medical University","ror":"https://ror.org/05w21nn13","country_code":"CN","type":"education","lineage":["https://openalex.org/I151075929"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huan Li","raw_affiliation_strings":["Army Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Army Medical University","institution_ids":["https://openalex.org/I151075929"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5122762542","display_name":"Haode Shen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I151075929","display_name":"Army Medical University","ror":"https://ror.org/05w21nn13","country_code":"CN","type":"education","lineage":["https://openalex.org/I151075929"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haode Shen","raw_affiliation_strings":["Army Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Army Medical University","institution_ids":["https://openalex.org/I151075929"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161337610","display_name":"Kun Xu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I151075929","display_name":"Army Medical University","ror":"https://ror.org/05w21nn13","country_code":"CN","type":"education","lineage":["https://openalex.org/I151075929"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kun Xu","raw_affiliation_strings":["Army Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Army Medical University","institution_ids":["https://openalex.org/I151075929"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019500141","display_name":"Qin Pi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I151075929","display_name":"Army Medical University","ror":"https://ror.org/05w21nn13","country_code":"CN","type":"education","lineage":["https://openalex.org/I151075929"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qin Pi","raw_affiliation_strings":["Army Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Army Medical University","institution_ids":["https://openalex.org/I151075929"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161356930","display_name":"Zhaoyang Zhong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I151075929","display_name":"Army Medical University","ror":"https://ror.org/05w21nn13","country_code":"CN","type":"education","lineage":["https://openalex.org/I151075929"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhaoyang Zhong","raw_affiliation_strings":["Army Medical University","Chongqing University of Chinese Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Army Medical University","institution_ids":["https://openalex.org/I151075929"]},{"raw_affiliation_string":"Chongqing University of Chinese Medicine","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003415396","display_name":"Weidong Tong","orcid":"https://orcid.org/0000-0001-6150-9941","observed_orcids":["https://orcid.org/0000-0001-6150-9941"]},"institutions":[{"id":"https://openalex.org/I151075929","display_name":"Army Medical University","ror":"https://ror.org/05w21nn13","country_code":"CN","type":"education","lineage":["https://openalex.org/I151075929"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Weidong Tong","raw_affiliation_strings":["Army Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Army Medical University","institution_ids":["https://openalex.org/I151075929"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5161361898","display_name":"Fan Li","orcid":"https://orcid.org/0009-0005-2054-4309","observed_orcids":["https://orcid.org/0009-0005-2054-4309"]},"institutions":[{"id":"https://openalex.org/I151075929","display_name":"Army Medical University","ror":"https://ror.org/05w21nn13","country_code":"CN","type":"education","lineage":["https://openalex.org/I151075929"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Fan Li","raw_affiliation_strings":["Army Medical University"],"raw_orcid":"https://orcid.org/0009-0005-2054-4309","affiliations":[{"raw_affiliation_string":"Army Medical University","institution_ids":["https://openalex.org/I151075929"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5003415396","https://openalex.org/A5161361898"],"corresponding_institution_ids":["https://openalex.org/I151075929"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"10"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments","score":0.9297000169754028,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments","score":0.9297000169754028,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":0.029999999329447746,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.02070000022649765,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/locally-advanced-rectal-cancer","display_name":"locally advanced rectal cancer","score":0.9890000224113464},{"id":"https://openalex.org/keywords/pathological-complete-response","display_name":"pathological complete response","score":0.949999988079071},{"id":"https://openalex.org/keywords/endorectal-ultrasound","display_name":"endorectal ultrasound","score":0.953000009059906},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"magnetic resonance imaging","score":0.49300000071525574},{"id":"https://openalex.org/keywords/chemoimmunotherapy","display_name":"chemoimmunotherapy","score":0.9599999785423279},{"id":"https://openalex.org/keywords/mismatch-repair-deficiency","display_name":"mismatch repair deficiency","score":0.765999972820282},{"id":"https://openalex.org/keywords/tumor-response-assessment","display_name":"tumor response assessment","score":0.8069999814033508},{"id":"https://openalex.org/keywords/diagnostic-accuracy","display_name":"diagnostic accuracy","score":0.7870000004768372}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.939300000667572},{"id":"https://openalex.org/C2780790343","wikidata":"https://www.wikidata.org/wiki/Q5090610","display_name":"Chemoimmunotherapy","level":4,"score":0.8105000257492065},{"id":"https://openalex.org/C186282968","wikidata":"https://www.wikidata.org/wiki/Q1434261","display_name":"McNemar's test","level":2,"score":0.694100022315979},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.6274999976158142},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.6248000264167786},{"id":"https://openalex.org/C3019096185","wikidata":"https://www.wikidata.org/wiki/Q1340863","display_name":"Complete response","level":3,"score":0.5929999947547913},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.4961000084877014},{"id":"https://openalex.org/C2778292576","wikidata":"https://www.wikidata.org/wiki/Q6991934","display_name":"Neoadjuvant therapy","level":4,"score":0.4657999873161316},{"id":"https://openalex.org/C207886595","wikidata":"https://www.wikidata.org/wiki/Q1456138","display_name":"Pathological","level":2,"score":0.4124000072479248},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.38830000162124634},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.37049999833106995},{"id":"https://openalex.org/C3020132585","wikidata":"https://www.wikidata.org/wiki/Q2671652","display_name":"Diagnostic accuracy","level":2,"score":0.32339999079704285},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.32260000705718994},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.3043000102043152},{"id":"https://openalex.org/C198433322","wikidata":"https://www.wikidata.org/wiki/Q3910099","display_name":"Predictive value of tests","level":2,"score":0.2962000072002411},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.29589998722076416},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.29499998688697815},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.29440000653266907},{"id":"https://openalex.org/C2779984678","wikidata":"https://www.wikidata.org/wiki/Q2145898","display_name":"Response Evaluation Criteria in Solid Tumors","level":4,"score":0.29269999265670776},{"id":"https://openalex.org/C160798450","wikidata":"https://www.wikidata.org/wiki/Q4230870","display_name":"Concordance","level":2,"score":0.29109999537467957},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.28780001401901245},{"id":"https://openalex.org/C143753070","wikidata":"https://www.wikidata.org/wiki/Q162564","display_name":"Ultrasound","level":2,"score":0.28529998660087585},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.28450000286102295},{"id":"https://openalex.org/C2778424827","wikidata":"https://www.wikidata.org/wiki/Q5090613","display_name":"Chemoradiotherapy","level":3,"score":0.2770000100135803}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1080/14796694.2026.2760122","doi":"https://doi.org/10.1080/14796694.2026.2760122","is_oa":false,"landing_page_url":"https://doi.org/10.1080/14796694.2026.2760122","pdf_url":null,"source":{"id":"https://openalex.org/S174572715","display_name":"Future Oncology","issn_l":"1479-6694","issn":["1479-6694","1744-8301"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310321119","host_organization_name":"Future Medicine","host_organization_lineage":["https://openalex.org/P4310321119"],"host_organization_lineage_names":["Future Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Future Oncology","raw_type":"journal-article"},{"id":"pmid:43001364","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/43001364","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Future oncology (London, England)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W2006621367","https://openalex.org/W2012559570","https://openalex.org/W2051667674","https://openalex.org/W2078566526","https://openalex.org/W2173887102","https://openalex.org/W2194760470","https://openalex.org/W2312491311","https://openalex.org/W2465379206","https://openalex.org/W2758695930","https://openalex.org/W2790898414","https://openalex.org/W2809278331","https://openalex.org/W2811163192","https://openalex.org/W2916620496","https://openalex.org/W2921248694","https://openalex.org/W2996259783","https://openalex.org/W3033633386","https://openalex.org/W3092072056","https://openalex.org/W3208809668","https://openalex.org/W4224274396","https://openalex.org/W4306250770","https://openalex.org/W4311849871","https://openalex.org/W4313250877","https://openalex.org/W4320893511","https://openalex.org/W4379284138","https://openalex.org/W4392757196","https://openalex.org/W4394628304","https://openalex.org/W4400183110","https://openalex.org/W4400306888","https://openalex.org/W4402909493","https://openalex.org/W4403035486","https://openalex.org/W4406116315","https://openalex.org/W4406893677","https://openalex.org/W4409690276","https://openalex.org/W4410163586","https://openalex.org/W4411192693","https://openalex.org/W4411921608","https://openalex.org/W4412392749","https://openalex.org/W4413415050","https://openalex.org/W4415400891","https://openalex.org/W4415656019","https://openalex.org/W4416247600","https://openalex.org/W7128428708","https://openalex.org/W7139919722","https://openalex.org/W7154618791","https://openalex.org/W7164300360","https://openalex.org/W7165061723","https://openalex.org/W7172336174"],"related_works":["https://openalex.org/W4403035486","https://openalex.org/W4394628304","https://openalex.org/W3133549703","https://openalex.org/W4406116315","https://openalex.org/W4411682387","https://openalex.org/W2909604360","https://openalex.org/W4414012755","https://openalex.org/W7221666808","https://openalex.org/W7162627085","https://openalex.org/W2946938586"],"abstract_inverted_index":{"BACKGROUND:":[0],"Accurate":[1],"imaging-based":[2],"response":[3,37,75,115,182],"assessment":[4],"is":[5],"essential":[6],"for":[7,33,180],"proficient":[8],"mismatch":[9],"repair":[10],"(pMMR)":[11],"locally":[12],"advanced":[13],"rectal":[14],"cancer":[15],"(LARC).":[16],"This":[17,48],"study":[18,51],"aimed":[19],"to":[20],"evaluate":[21],"the":[22,172,178],"diagnostic":[23,152],"performance":[24,56],"of":[25,97,174],"MRI,":[26],"endorectal":[27],"ultrasound":[28],"(ERUS)":[29],"and":[30,62,77,84,95,100,104,106,109,139,162,177],"18F-FAPI":[31,148],"PET/MRI":[32,149],"identifying":[34],"pathological":[35],"complete":[36,74,114],"(pCR)":[38],"after":[39],"neoadjuvant":[40],"short-course":[41],"radiotherapy":[42],"(SCRT)":[43],"followed":[44,127],"by":[45,128],"chemoimmunotherapy.":[46],"METHODS:":[47],"single-center":[49],"retrospective":[50],"included":[52],"143":[53],"patients.":[54],"Diagnostic":[55],"was":[57],"assessed":[58,70],"using":[59],"sensitivity,":[60,93],"specificity,":[61,94],"accuracy":[63,96],"with":[64,119],"95%":[65],"confidence":[66],"intervals.":[67],"Cohen's":[68],"\u03ba":[69],"agreement":[71,118],"between":[72],"imaging-defined":[73],"(iCR)":[76],"pCR.":[78],"Paired":[79],"comparisons":[80],"used":[81],"Cochran's":[82],"Q":[83],"Holm-adjusted":[85],"exact":[86],"McNemar":[87],"tests.":[88],"RESULTS:":[89],"=":[90,122],"25)":[91],"achieved":[92,130],"4.76%,":[98],"98.18%,":[99],"48.31%;":[101],"30.95%,":[102],"87.18%,":[103],"58.02%;":[105],"60.0%,":[107],"100.0%,":[108],"84.0%,":[110],"respectively.":[111],"PET/MRI-assessed":[112],"imaging":[113,175],"showed":[116,141,150],"substantial":[117],"pCR":[120,132],"(\u03ba":[121],"0.643).":[123],"CONCLUSION:":[124],"Neoadjuvant":[125],"SCRT":[126],"chemoimmunotherapy":[129],"high":[131,146],"rates":[133],"in":[134,154],"pMMR":[135],"LARC.":[136],"Conventional":[137],"MRI":[138],"ERUS":[140],"limited":[142,163],"sensitivity":[143,161],"despite":[144],"relatively":[145],"specificity.":[147],"potential":[151],"utility":[153],"a":[155],"small":[156],"subgroup,":[157],"but":[158],"its":[159],"moderate":[160],"sample":[164],"size":[165],"warrant":[166],"further":[167],"validation.":[168],"These":[169],"findings":[170],"highlight":[171],"limitations":[173],"alone":[176],"need":[179],"comprehensive":[181],"assessment.":[183]},"counts_by_year":[],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2026-11-10T00:00:00"}