{"id":"https://openalex.org/W7225646643","doi":"https://doi.org/10.1186/s12711-026-01101-5","title":"PedXylo: an integrated platform for autosomal and sex-linked pedigree analysis","display_name":"PedXylo: an integrated platform for autosomal and sex-linked pedigree analysis","publication_year":2026,"publication_date":"2026-11-09","ids":{"openalex":"https://openalex.org/W7225646643","doi":"https://doi.org/10.1186/s12711-026-01101-5","pmid":"https://pubmed.ncbi.nlm.nih.gov/43004177"},"language":"en","primary_location":{"id":"doi:10.1186/s12711-026-01101-5","doi":"https://doi.org/10.1186/s12711-026-01101-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12711-026-01101-5","pdf_url":"https://link.springer.com/content/pdf/10.1186/s12711-026-01101-5.pdf","source":{"id":"https://openalex.org/S184365670","display_name":"Genetics Selection Evolution","issn_l":"0999-193X","issn":["0999-193X","1297-9686"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","jufo-2","ki-jl-1","medline","norway-2","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genetics Selection Evolution","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://link.springer.com/content/pdf/10.1186/s12711-026-01101-5.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039353882","display_name":"Gy\u00f6rgy K\u00f6v\u00e9r","orcid":"https://orcid.org/0009-0002-8878-4163","observed_orcids":["https://orcid.org/0009-0002-8878-4163","https://orcid.org/0000-0003-1788-8213"]},"institutions":[{"id":"https://openalex.org/I1290523313","display_name":"Magyar Agr\u00e1r- \u00e9s \u00c9lettudom\u00e1nyi Egyetem","ror":"https://ror.org/01394d192","country_code":"HU","type":"education","lineage":["https://openalex.org/I1290523313"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"G. K\u00f6v\u00e9r","raw_affiliation_strings":["Hungarian University of Agriculture and Life Sciences - Institute of Animal Sciences (MATE), Kaposv\u00e1r, Hungary"],"raw_orcid":"https://orcid.org/0009-0002-8878-4163","affiliations":[{"raw_affiliation_string":"Hungarian University of Agriculture and Life Sciences - Institute of Animal Sciences (MATE), Kaposv\u00e1r, Hungary","institution_ids":["https://openalex.org/I1290523313"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007633471","display_name":"Istv\u00e1n Nagy","orcid":"https://orcid.org/0000-0003-0247-6638","observed_orcids":["https://orcid.org/0000-0003-0247-6638"]},"institutions":[{"id":"https://openalex.org/I1290523313","display_name":"Magyar Agr\u00e1r- \u00e9s \u00c9lettudom\u00e1nyi Egyetem","ror":"https://ror.org/01394d192","country_code":"HU","type":"education","lineage":["https://openalex.org/I1290523313"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"I. Nagy","raw_affiliation_strings":["Hungarian University of Agriculture and Life Sciences - Institute of Animal Sciences (MATE), Kaposv\u00e1r, Hungary"],"raw_orcid":"https://orcid.org/0000-0003-0247-6638","affiliations":[{"raw_affiliation_string":"Hungarian University of Agriculture and Life Sciences - Institute of Animal Sciences (MATE), Kaposv\u00e1r, Hungary","institution_ids":["https://openalex.org/I1290523313"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067771720","display_name":"Anh T. H. Nguyen","orcid":"https://orcid.org/0009-0007-4541-4302","observed_orcids":["https://orcid.org/0009-0007-4541-4302"]},"institutions":[{"id":"https://openalex.org/I1290523313","display_name":"Magyar Agr\u00e1r- \u00e9s \u00c9lettudom\u00e1nyi Egyetem","ror":"https://ror.org/01394d192","country_code":"HU","type":"education","lineage":["https://openalex.org/I1290523313"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"A. T. Nguyen","raw_affiliation_strings":["Hungarian University of Agriculture and Life Sciences - Institute of Animal Sciences (MATE), Kaposv\u00e1r, Hungary"],"raw_orcid":"https://orcid.org/0009-0007-4541-4302","affiliations":[{"raw_affiliation_string":"Hungarian University of Agriculture and Life Sciences - Institute of Animal Sciences (MATE), Kaposv\u00e1r, Hungary","institution_ids":["https://openalex.org/I1290523313"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042266021","display_name":"J. Farkas","orcid":"https://orcid.org/0000-0003-3999-1051","observed_orcids":["https://orcid.org/0000-0003-3999-1051","https://orcid.org/0000-0001-6794-854X"]},"institutions":[{"id":"https://openalex.org/I1290523313","display_name":"Magyar Agr\u00e1r- \u00e9s \u00c9lettudom\u00e1nyi Egyetem","ror":"https://ror.org/01394d192","country_code":"HU","type":"education","lineage":["https://openalex.org/I1290523313"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"J. Farkas","raw_affiliation_strings":["Hungarian University of Agriculture and Life Sciences - Institute of Animal Sciences (MATE), Kaposv\u00e1r, Hungary"],"raw_orcid":"https://orcid.org/0000-0001-6794-854X","affiliations":[{"raw_affiliation_string":"Hungarian University of Agriculture and Life Sciences - Institute of Animal Sciences (MATE), Kaposv\u00e1r, Hungary","institution_ids":["https://openalex.org/I1290523313"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082341333","display_name":"Johann S\u00f6lkner","orcid":"https://orcid.org/0000-0002-1517-5829","observed_orcids":["https://orcid.org/0000-0002-1517-5829"]},"institutions":[{"id":"https://openalex.org/I92869138","display_name":"BOKU University","ror":"https://ror.org/057ff4y42","country_code":"AT","type":"education","lineage":["https://openalex.org/I92869138"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"J. S\u00f6lkner","raw_affiliation_strings":["BOKU University, Vienna, Austria"],"raw_orcid":"https://orcid.org/0000-0002-1517-5829","affiliations":[{"raw_affiliation_string":"BOKU University, Vienna, Austria","institution_ids":["https://openalex.org/I92869138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040606652","display_name":"Lubo\u0161 VOSTR\u00dd","orcid":"https://orcid.org/0000-0001-9778-980X","observed_orcids":["https://orcid.org/0000-0001-9778-980X"]},"institutions":[{"id":"https://openalex.org/I205984670","display_name":"Czech University of Life Sciences Prague","ror":"https://ror.org/0415vcw02","country_code":"CZ","type":"education","lineage":["https://openalex.org/I205984670"]}],"countries":["CZ"],"is_corresponding":false,"raw_author_name":"L. Vostry","raw_affiliation_strings":["Czech University of Life Science Prague, Prague, Czechia"],"raw_orcid":"https://orcid.org/0000-0001-9778-980X","affiliations":[{"raw_affiliation_string":"Czech University of Life Science Prague, Prague, Czechia","institution_ids":["https://openalex.org/I205984670"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041653609","display_name":"Ino \u010curik","orcid":"https://orcid.org/0000-0001-7090-1654","observed_orcids":["https://orcid.org/0000-0001-7090-1654"]},"institutions":[{"id":"https://openalex.org/I1290523313","display_name":"Magyar Agr\u00e1r- \u00e9s \u00c9lettudom\u00e1nyi Egyetem","ror":"https://ror.org/01394d192","country_code":"HU","type":"education","lineage":["https://openalex.org/I1290523313"]},{"id":"https://openalex.org/I181343428","display_name":"University of Zagreb","ror":"https://ror.org/00mv6sv71","country_code":"HR","type":"education","lineage":["https://openalex.org/I181343428"]}],"countries":["HR","HU"],"is_corresponding":false,"raw_author_name":"I. Curik","raw_affiliation_strings":["Faculty of Agriculture, University of Zagreb, Zagreb, Croatia","Hungarian University of Agriculture and Life Sciences - Institute of Animal Sciences (MATE), Kaposv\u00e1r, Hungary"],"raw_orcid":"https://orcid.org/0000-0001-7090-1654","affiliations":[{"raw_affiliation_string":"Faculty of Agriculture, University of Zagreb, Zagreb, Croatia","institution_ids":["https://openalex.org/I181343428"]},{"raw_affiliation_string":"Hungarian University of Agriculture and Life Sciences - Institute of Animal Sciences (MATE), Kaposv\u00e1r, Hungary","institution_ids":["https://openalex.org/I1290523313"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047418076","display_name":"Dalibor Hr\u0161ak","orcid":"https://orcid.org/0000-0002-1462-7424","observed_orcids":["https://orcid.org/0000-0002-1462-7424"]},"institutions":[{"id":"https://openalex.org/I4210123216","display_name":"Ru\u0111er Bo\u0161kovi\u0107 Institute","ror":"https://ror.org/02mw21745","country_code":"HR","type":"facility","lineage":["https://openalex.org/I4210123216"]}],"countries":["HR"],"is_corresponding":true,"raw_author_name":"D. Hr\u0161ak","raw_affiliation_strings":["Ru\u0111er Bo\u0161kovi\u0107 Institute, Zagreb, Croatia. dalibor.hrsak@irb.hr"],"raw_orcid":"https://orcid.org/0000-0002-1462-7424","affiliations":[{"raw_affiliation_string":"Ru\u0111er Bo\u0161kovi\u0107 Institute, Zagreb, Croatia. dalibor.hrsak@irb.hr","institution_ids":["https://openalex.org/I4210123216"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5047418076"],"corresponding_institution_ids":["https://openalex.org/I4210123216"],"apc_list":{"value":2390,"currency":"USD","value_usd":2390},"apc_paid":{"value":2390,"currency":"USD","value_usd":2390},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"58","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10594","display_name":"Genetic and phenotypic traits in livestock","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10594","display_name":"Genetic and phenotypic traits in livestock","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10012","display_name":"Genetic diversity and population structure","score":0.007899999618530273,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pedigree-analysis","display_name":"pedigree analysis","score":0.9150000214576721},{"id":"https://openalex.org/keywords/x-linked-inheritance","display_name":"X-linked inheritance","score":0.75},{"id":"https://openalex.org/keywords/inbreeding-coefficient","display_name":"inbreeding coefficient","score":0.9160000085830688},{"id":"https://openalex.org/keywords/effective-population-size","display_name":"effective population size","score":0.9470000267028809},{"id":"https://openalex.org/keywords/european-bison","display_name":"European bison","score":0.8289999961853027},{"id":"https://openalex.org/keywords/holstein-cattle","display_name":"Holstein cows","score":0.7409999966621399}],"concepts":[{"id":"https://openalex.org/C2777782036","wikidata":"https://www.wikidata.org/wiki/Q38978","display_name":"Inbreeding","level":3,"score":0.8504999876022339},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6829000115394592},{"id":"https://openalex.org/C134925867","wikidata":"https://www.wikidata.org/wiki/Q186380","display_name":"Autosome","level":4,"score":0.6018000245094299},{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.5608000159263611},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5163999795913696},{"id":"https://openalex.org/C2780902518","wikidata":"https://www.wikidata.org/wiki/Q6033780","display_name":"Inheritance (genetic algorithm)","level":3,"score":0.44839999079704285},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.423799991607666},{"id":"https://openalex.org/C2016182","wikidata":"https://www.wikidata.org/wiki/Q227675","display_name":"Animal breeding","level":2,"score":0.3952000141143799},{"id":"https://openalex.org/C48044578","wikidata":"https://www.wikidata.org/wiki/Q727490","display_name":"Scalability","level":2,"score":0.39480000734329224},{"id":"https://openalex.org/C22593422","wikidata":"https://www.wikidata.org/wiki/Q3242583","display_name":"Pedigree chart","level":3,"score":0.3610999882221222},{"id":"https://openalex.org/C81917197","wikidata":"https://www.wikidata.org/wiki/Q628760","display_name":"Selection (genetic algorithm)","level":2,"score":0.3610000014305115},{"id":"https://openalex.org/C2776817793","wikidata":"https://www.wikidata.org/wiki/Q6553369","display_name":"Lineage (genetic)","level":3,"score":0.3580000102519989},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.34220001101493835},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.3411000072956085},{"id":"https://openalex.org/C3641667","wikidata":"https://www.wikidata.org/wiki/Q1295959","display_name":"Effective population size","level":4,"score":0.3343999981880188},{"id":"https://openalex.org/C1244910","wikidata":"https://www.wikidata.org/wiki/Q1481109","display_name":"Inbreeding depression","level":4,"score":0.3147999942302704},{"id":"https://openalex.org/C2779530757","wikidata":"https://www.wikidata.org/wiki/Q1207505","display_name":"Quality (philosophy)","level":2,"score":0.3034000098705292},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.29019999504089355},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.28610000014305115},{"id":"https://openalex.org/C113174947","wikidata":"https://www.wikidata.org/wiki/Q2859736","display_name":"Tree (set theory)","level":2,"score":0.28119999170303345},{"id":"https://openalex.org/C81941488","wikidata":"https://www.wikidata.org/wiki/Q853421","display_name":"Quantitative trait locus","level":3,"score":0.2702000141143799},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.26269999146461487},{"id":"https://openalex.org/C2776116246","wikidata":"https://www.wikidata.org/wiki/Q21067469","display_name":"Runs of Homozygosity","level":5,"score":0.2614000141620636},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.26030001044273376},{"id":"https://openalex.org/C85721925","wikidata":"https://www.wikidata.org/wiki/Q31151","display_name":"Population genetics","level":3,"score":0.2599000036716461},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.25609999895095825},{"id":"https://openalex.org/C23085057","wikidata":"https://www.wikidata.org/wiki/Q5532877","display_name":"Genetic analysis","level":3,"score":0.2549000084400177}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007178","descriptor_name":"Inbreeding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010375","descriptor_name":"Pedigree","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014960","descriptor_name":"X Chromosome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1186/s12711-026-01101-5","doi":"https://doi.org/10.1186/s12711-026-01101-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12711-026-01101-5","pdf_url":"https://link.springer.com/content/pdf/10.1186/s12711-026-01101-5.pdf","source":{"id":"https://openalex.org/S184365670","display_name":"Genetics Selection Evolution","issn_l":"0999-193X","issn":["0999-193X","1297-9686"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","jufo-2","ki-jl-1","medline","norway-2","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genetics Selection Evolution","raw_type":"journal-article"},{"id":"pmid:43004177","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/43004177","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genetics, selection, evolution : GSE","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1186/s12711-026-01101-5","doi":"https://doi.org/10.1186/s12711-026-01101-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12711-026-01101-5","pdf_url":"https://link.springer.com/content/pdf/10.1186/s12711-026-01101-5.pdf","source":{"id":"https://openalex.org/S184365670","display_name":"Genetics Selection Evolution","issn_l":"0999-193X","issn":["0999-193X","1297-9686"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","jufo-2","ki-jl-1","medline","norway-2","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genetics Selection Evolution","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321006","display_name":"Grantov\u00e1 Agentura \u010cesk\u00e9 Republiky","ror":"https://ror.org/01pv73b02"},{"id":"https://openalex.org/F4320322674","display_name":"Hrvatska Zaklada za Znanost","ror":"https://ror.org/03n51vw80"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225646643.pdf","grobid_xml":"https://content.openalex.org/works/W7225646643.grobid-xml"},"referenced_works_count":53,"referenced_works":["https://openalex.org/W1501791679","https://openalex.org/W1519581284","https://openalex.org/W1548792873","https://openalex.org/W1577657159","https://openalex.org/W1967919799","https://openalex.org/W1969242230","https://openalex.org/W1975831721","https://openalex.org/W1980901426","https://openalex.org/W1984046516","https://openalex.org/W1997424334","https://openalex.org/W2000102987","https://openalex.org/W2002028392","https://openalex.org/W2002794144","https://openalex.org/W2014261842","https://openalex.org/W2025311319","https://openalex.org/W2039599917","https://openalex.org/W2041000916","https://openalex.org/W2048468713","https://openalex.org/W2071246992","https://openalex.org/W2076297801","https://openalex.org/W2076658681","https://openalex.org/W2076773226","https://openalex.org/W2087819223","https://openalex.org/W2102982283","https://openalex.org/W2112212216","https://openalex.org/W2113916812","https://openalex.org/W2115025364","https://openalex.org/W2119518325","https://openalex.org/W2134206074","https://openalex.org/W2137728213","https://openalex.org/W2138987732","https://openalex.org/W2152198622","https://openalex.org/W2158645924","https://openalex.org/W2164050502","https://openalex.org/W2169366247","https://openalex.org/W2322730851","https://openalex.org/W2331613197","https://openalex.org/W2513894064","https://openalex.org/W2530141774","https://openalex.org/W2800853838","https://openalex.org/W2973109820","https://openalex.org/W3017321895","https://openalex.org/W3033625615","https://openalex.org/W3042318275","https://openalex.org/W3097600806","https://openalex.org/W3159607762","https://openalex.org/W3199197691","https://openalex.org/W4235071074","https://openalex.org/W4308914134","https://openalex.org/W4399887400","https://openalex.org/W4414945384","https://openalex.org/W4416156118","https://openalex.org/W7155054284"],"related_works":["https://openalex.org/W1997424334","https://openalex.org/W327390192","https://openalex.org/W4409534359","https://openalex.org/W2129518880","https://openalex.org/W3042307767","https://openalex.org/W2126547191","https://openalex.org/W7171719337","https://openalex.org/W4231317119","https://openalex.org/W2139810621","https://openalex.org/W2274452415"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"Pedigree-based":[2],"inference":[3,239],"remains":[4],"central":[5],"to":[6,10,37,249],"animal":[7,245],"breeding":[8,246],"and":[9,13,34,52,67,79,93,97,127,141,143,150,180,184,193,205,212,247,255,267,291],"conservation,":[11,253],"evolutionary,":[12,254],"human-isolate":[14,256],"research.":[15,257],"However,":[16],"existing":[17],"pedigree":[18,63,138,145,211,219,282],"software":[19,49,285],"offers":[20],"no":[21,30],"integrated":[22,62],"support":[23],"for":[24,50,190,237,241],"X-linked":[25],"analysis,":[26,261],"limited":[27,35],"partial-decomposition":[28],"functionality,":[29],"standardised":[31],"pedigree-quality":[32,269],"framework,":[33],"scalability":[36,214],"industry-sized":[38],"pedigrees.":[39],"Results":[40],"We":[41,197],"developed":[42],"PedXylo,":[43],"which":[44],"extends":[45],"previously":[46,277],"published":[47],"gene-dropping":[48],"ancestral":[51,80,265],"partial":[53,262],"inbreeding":[54,88,178],"analysis":[55],"into":[56],"a":[57,111,206,216,226,233],"comprehensive":[58],"pedigree-analysis":[59],"platform":[60],"with":[61,156,280,289],"management,":[64],"quality":[65,121],"assessment,":[66],"effective-population-size":[68],"estimation.":[69],"PedXylo":[70,231],"computes":[71],"classical":[72],"(F),":[73],"Kalinowski\u2019s":[74],"new":[75,134,268],"(F":[76,81],"N":[77],"),":[78],"aB":[82],",":[83,86],"F":[84],"aK":[85],"AHC)":[87],"coefficients":[89],"on":[90,215,225],"both":[91,108,191],"autosomes":[92,192],"the":[94,136,144,159,194,202],"X":[95,182,195],"chromosome":[96],"provides":[98,232],"ancestor-resolved":[99],"(partial)":[100],"decomposition":[101,263],"of":[102,177,264],"all":[103],"five":[104],"coefficient":[105],"families":[106],"in":[107,116,158,221,244,252],"inheritance":[109],"modes,":[110],"combination":[112],"not":[113,169,276],"currently":[114],"available":[115,281,288],"any":[117],"other":[118],"tool.":[119],"Pedigree":[120],"is":[122,286],"summarised":[123],"through":[124],"complete":[125],"(CGE)":[126],"discrete":[128],"(DGE)":[129],"generation":[130],"equivalents":[131,139],"alongside":[132],"two":[133],"metrics:":[135],"asymmetrical":[137],"(cAPE":[140],"mAPE)":[142],"tree":[146],"imbalance":[147],"(PTI).":[148],"cAPE":[149],"mAPE":[151],"were":[152],"only":[153],"weakly":[154],"correlated":[155],"CGE":[157],"European":[160,209],"bison":[161,210],"reference":[162],"population,":[163],"indicating":[164],"that":[165,274],"they":[166],"capture":[167],"information":[168],"represented":[170],"by":[171],"depth-based":[172],"metrics":[173],"alone.":[174],"Per-individual":[175],"rates":[176],"(\u0394F":[179],"\u0394F":[181],")":[183],"effective":[185],"population":[186],"sizes":[187],"are":[188],"estimated":[189],"chromosome.":[196],"illustrate":[198],"these":[199],"analyses":[200],"using":[201],"Habsburg":[203],"lineage":[204],"long-term":[207],"captive":[208],"demonstrate":[213],"23.2-million-individual":[217],"Holstein":[218],"analysed":[220],"approximately":[222],"18":[223],"h":[224],"single":[227],"40-thread":[228],"workstation.":[229],"Conclusions":[230],"unified,":[234],"scalable":[235],"framework":[236],"pedigree-based":[238],"suitable":[240],"routine":[242],"application":[243],"applicable":[248],"wide":[250],"use":[251],"By":[258],"integrating":[259],"sex-linked":[260],"coefficients,":[266],"metrics,":[270],"it":[271],"enables":[272],"hypotheses":[273],"could":[275],"be":[278],"tested":[279],"software.":[283],"The":[284],"freely":[287],"documentation":[290],"worked":[292],"examples.":[293]},"counts_by_year":[],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2026-11-10T00:00:00"}